Partial characterization of human C5a anaphylatoxin. I. Chemical description of the carbohydrate and polypeptide prtions of human C5a.

No abstract is available for this paper.

• Publication year

  1976

• Venue

  Journal of Immunology

• Publication date

  1976-11-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  PMID 1002996
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Formation of anaphylatoxin in human serum

  2005cited by this paper
• Release of histamine from rat mast cells by the complement peptides C3a and C5a.

  1975cited by this paper
• Purification and partial characterization of human and porcine C3a anaphylatoxin.

  1975cited by this paper
• Regeneration of amino acids from thiazolinones formed in the Edman degradation.

  1975cited by this paper
• Circular dichroism of C3a anaphylatoxin. Effects of pH, heat, guanidinium chloride, and mercaptoethanol on conformation and function.

  1975cited by this paper
• Circular dichroism of C5a anaphylatoxin of porcine complement.

  1974cited by this paper
• A high resolution PAS stain for polyacrylamide gel electrophoresis.

  1973cited by this paper
• FORMATION OF C3a AND C5a ANAPHYLATOXINS IN WHOLE HUMAN SERUM AFTER INHIBITION OF THE ANAPHYLATOXIN INACTIVATOR

  1973cited by this paper
• Determination of the tryptophan content of proteins by ion exchange chromatography of alkaline hydrolysates.

  1972cited by this paper
• Chemistry and biology of the anaphylatoxin related serum peptide system. I. Purification, crystallization and properties of classical anaphylatoxin from rat serum

  1972cited by this paper
• Structural elements of anaphylatoxin obtained by contact activation of hog serum.

  1972cited by this paper
• Human erythrocyte membrane glycoprotein: a re-evaluation of the molecular weight as determined by SDS polyacrylamide gel electrophoresis.

  1971cited by this paper
• An assessment of methanolysis and other factors used in the analysis of carbohydrate-containing materials.

  1971cited by this paper
• Amino acid analysis of stained bands from polyacrylamide gels.

  1971cited by this paper
• The reliability of molecular weight determinations by dodecyl sulfate-polyacrylamide gel electrophoresis.

  1969cited by this paper
• A neutrophil chemotactic factor from human C'5.

  1969cited by this paper
• Analysis of amino acid phenylthiohydantoins by gas chromatography.

  1969cited by this paper
• THE DERIVATION OF TWO DISTINCT ANAPHYLATOXIN ACTIVITIES FROM THE THIRD AND FIFTH COMPONENTS OF HUMAN COMPLEMENT

  1968cited by this paper
• Preparation and some properties of anaphylatoxin from hog serum.

  1968cited by this paper
• Anaphylatoxin in Its Relation to the Complement System

  1967cited by this paper
• A protein sequenator.

  1967cited by this paper
• The gel-filtration behaviour of proteins related to their molecular weights over a wide range.

  1965cited by this paper
• [ON THE CHEMISTRY OF ANAPHYLATOXIN].

  1965cited by this paper
• The preparation and enzymatic hydrolysis of reduced and S-carboxymethylated proteins.

  1963cited by this paper
• Disk Electrophoresis of Basic Proteins and Peptides on Polyacrylamide Gels

  1962cited by this paper
• The determination of sugar in blood and spinal fluid with anthrone reagent.

  1955cited by this paper

• A naturally hypersensitive porcine model may help understand the mechanism of COVID-19 mRNA vaccine-induced rare (pseudo) allergic reactions: complement activation as a possible contributing factor

  2022cites this paper
• Mechanism of nanoparticle-induced hypersensitivity in pigs: complement or not complement?

  2018cites this paper
• Trends in current studies of phagocyte chemotaxis

  2014cites this paper
• EXPLORING THE POSSIBLE ROLE OF C3aR LIGATION ON INTESTINAL EPITHELIAL CELLS

  2014cites this paper
• Caracterização biológica e imunoquímica da peçonha da lagarta de Premolis semirufa, agente etiológico da pararamose, doença ocupacional dos seringueiros da Amazônia

  2013cites this paper
• Study of the capacity of Toll-like receptors to modulate pro-inflammatory responses mediated by receptors for the complement anaphylatoxin C5a

  2013cites this paper
• Anaphylatoxins: From Supposed Toxin Anaphylactics to Effective Mediators of the Early Events of Inflammation *

  2012cites this paper
• Neutrophil–Endothelial Cell Interactions

  2010cites this paper
• Decreased Survival of Human Breast Cancer Cells Expressing HER2/neu on In vitro Incubation with an Anti-HER2/neu Antibody Fused to C5a or C5adesArg

  2010cites this paper
• reased Survival of Human Breast Cancer Cells Expressing 2/neu on In vitro Incubation with an Anti-HER2/neu

  2010cites this paper
• Model for substrate interactions in C5a peptidase from Streptococcus pyogenes: A 1.9 A crystal structure of the active form of ScpA.

  2009cites this paper
• The role of the anaphylatoxins in health and disease.

  2009cites this paper
• Monocyte chemotaxis: a method for routine in vitro investigation using lactic dehydrogenase as a marker enzyme.

  2009cites this paper
• Transendothelial cell diapedesis of neutrophils in inflamed human skin

  2004cites this paper
• 15-Hydroxyeicosatetraenoic acid (15-HETE) specifically inhibits the LTB4-induced skin response

  2004cites this paper
• WETSEL AND KOLB

  2003cites this paper
• Innate Immunity in Viral Encephalitis: Role of C5

  2002cites this paper
• Bibliography Articles Cited in Commentaries

  2000cites this paper
• C5a receptor antagonists.

  1999cites this paper
• Age-dependent neutrophil and blood flow responsiveness in acute pulmonary inflammation in rabbits.

  1997cites this paper
• A selection system to study C5a-C5a-receptor interactions: phage display of a novel C5a anaphylatoxin, Fos-C5aAla27.

  1997cites this paper
• Nucleotide and corrected amino acid sequence of the functional recombinant rat anaphylatoxin C5a.

  1997cites this paper
• Epitope mapping of a C5a neutralizing mAb using a combined approach of phage display, synthetic peptides and site-directed mutagenesis.

  1996cites this paper
• A new biologic role for C3a and C3a desArg: regulation of TNF-alpha and IL-1 beta synthesis.

  1996cites this paper
• The Molecular Basis for Neutrophil Dysfunction in Early-Onset Periodontitis.

  1996cites this paper
• Inhibition of neutrophil chemotaxis by plasma of burned patients: effect of blood transfusion practice.

  1995cites this paper
• The extracellular neutral cysteine proteinase of Entamoeba histolytica degrades anaphylatoxins C3a and C5a.

  1995cites this paper
• C5a- and tumor necrosis factor-alpha-induced leukocytosis occurs independently of beta 2 integrins and L-selectin: differential effects on neutrophil adhesion molecule expression in vivo.

  1995cites this paper
• [Chemico-enzymatic synthesis, cloning and expression of a gene for an analog of human anaphylatoxin C5a].

  1995cites this paper
• Isolation of neutralizing anti-C5a monoclonal antibodies from a filamentous phage monovalent Fab display library.

  1994cites this paper
• Identification of a receptor-binding region in the core segment of the human anaphylatoxin C5a.

  1994cites this paper
• Human monocyte chemotaxis to complement‐derived chemotaxins is enhanced by Gc‐globulin

  1994cites this paper
• Primary structure and functional characterization of rat C5a: An anaphylatoxin with unusually high potency

  1994cites this paper
• Novel function of C4a anaphylatoxin. Release from monocytes of protein which inhibits monocyte chemotaxis.

  1993cites this paper
• The role of complement in pregnancy‐induced hypertensive disease

  1993cites this paper
• Inhibition of human monocyte functions by anthralin

  1992cites this paper
• Biologic activity of synthetic analogues of C5a anaphylatoxin.

  1992cites this paper
• Factor XIII-dependent generation of 5th complement component(C5)-derived monocyte chemotactic factor coinciding with plasma clotting.

  1992cites this paper
• Improvements in the minimum binding sequence of C5a: examination of His-67.

  1992cites this paper
• Neutrophil chemotactic factors promote leukocytosis. A common mechanism for cellular recruitment from bone marrow.

  1992cites this paper
• Activation of complement components C3 and C5 by a cysteine proteinase (gingipain-1) from Porphyromonas (Bacteroides) gingivalis.

  1992cites this paper
• Probucol pretreatment enhances the chemotaxis of mouse peritoneal macrophages.

  1992cites this paper
• Platelet activating factor stimulates intracellular calcium transients in human neutrophils: involvement of endogenous 5‐lipoxygenase products

  1992cites this paper
• Biochemical and biological characterization of NAP-1/IL-8-related cytokines in lesional psoriatic scale.

  1991cites this paper
• Identification and synthesis of a receptor binding site of human anaphylatoxin C5a.

  1991cites this paper
• Characterization of the C5a receptor on guinea pig platelets.

  1991cites this paper
• Complement C4-derived monocyte-directed chemotaxis-inhibitory factor. A molecular mechanism to cause polymorphonuclear leukocyte-predominant infiltration in rheumatoid arthritis synovial cavities.

  1991cites this paper
• Quantitative monitoring of acute experimental cutaneous pain and inflammatory vascular reactions. Effect of local analgesics, capsaicin and antihistamines.

  1991cites this paper
• Role of granulocytes and C5a in myocardial response to zymosan-activated serum.

  1991cites this paper
• The Short and Happy Life of Neutrophil Activation

  1990cites this paper
• Human C-reactive protein inhibits neutrophil chemotaxis in vitro: possible implications for the adult respiratory distress syndrome.

  1990cites this paper
• Chapter 2 Chemoattractant Receptors as Regulators of Phagocytic Cell Function

  1990cites this paper
• Chemotactic competence of neutrophils from neonatal calves

  1990cites this paper
• Fibronectin fragments containing the RGDS cell-binding domain mediate monocyte migration into the rabbit lung. A potential mechanism for C5 fragment-induced monocyte lung accumulation.

  1990cites this paper
• C5a-induced neutrophilia. A primary humoral mechanism for recruitment of neutrophils.

  1990cites this paper
• The tumor necrosis factor receptor and human neutrophil function. Deactivation and cross-deactivation of tumor necrosis factor-induced neutrophil responses by receptor down-regulation.

  1990cites this paper
• Interaction between chemoattractants and bacterial lipopolysaccharide in the induction and enhancement of neutrophil adhesion.

  1990cites this paper
• Recombinant Human Tumour Necrosis Factor β (Lymphotoxin) Lacks Chemotactic Activity for Human Peripheral Blood Neutrophils, Monocytes, and T Cells

  1989cites this paper
• Complement receptor expression on neutrophils at an inflammatory site, the Pseudomonas-infected lung in cystic fibrosis.

  1989cites this paper
• Role of complement-derived peptides in thrombocytopenia elicited by soluble aggregates of immunoglobulin G in the rat.

  1989cites this paper
• Effects of anti-C5a antibodies on human polymorphonuclear leukocyte function: chemotaxis, chemiluminescence, and lysosomal enzyme release.

  1989cites this paper
• Cessation of neutrophil influx in C5a-induced acute experimental arthritis is associated with loss of chemoattractant activity from the joint space.

  1989cites this paper
• Interleukin 1 and tumor necrosis factor stimulate human vascular endothelial cells to promote transendothelial neutrophil passage.

  1989cites this paper
• Adherence of neutrophils to cultured human microvascular endothelial cells. Stimulation by chemotactic peptides and lipid mediators and dependence upon the Mac-1, LFA-1, p150,95 glycoprotein family.

  1989cites this paper
• Secretion of novel and homologous neutrophil-activating peptides by LPS-stimulated human endothelial cells.

  1989cites this paper
• Absence of induction of IL-1 production in human monocytes by complement fragments.

  1989cites this paper
• Chemotactic Factor for Polymorphonuclear Leukocytes Derived from Human Lung Giant Cell Carcinoma Lu65 Cells

  1989cites this paper
• Identification of different charged species of a human monocyte derived neutrophil activating peptide (MONAP).

  1988cites this paper
• Tumor necrosis factor/cachectin. Induction of hemorrhagic necrosis in normal tissue requires the fifth component of complement (C5)

  1988cites this paper
• Complement and Complement Reactions

  1988cites this paper
• Biological properties of human C5a: selected in vitro and in vivo studies.

  1988cites this paper
• Monocyte retention and migration in pulmonary inflammation. Requirement for neutrophils.

  1988cites this paper
• Effects of cyclosporine A treatment on psoriasis. I: Influence of low-dose cyclosporine on human monocyte function in vitro.

  1988cites this paper
• Comparison of model and nuclear magnetic resonance structures for the human inflammatory protein C5a

  1988cites this paper
• Leukocyte chemoattractant receptors.

  1988cites this paper
• Human C5a anaphylatoxin: gene synthesis, expression, and recovery of biologically active material from Escherichia coli.

  1988cites this paper
• Enhancement of pulmonary inflammation by PGE2: evidence for a vasodilator effect.

  1988cites this paper
• Atopic dermatitis: influence of bacterial infections on human monocyte and neutrophil granulocyte functional activities.

  1988cites this paper
• Bacterial Lipopolysaccharide Enhances Chemoattractant‐Induced Elastase Secretion by Human Neutrophils

  1988cites this paper
• Gc-globulin (vitamin D-binding protein) enhances the neutrophil chemotactic activity of C5a and C5a des Arg.

  1988cites this paper
• Rapid and simple measurement of human C5a-des-Arg level in plasma or serum using monoclonal antibodies.

  1987cites this paper
• Methotrexate inhibits the human C5a-induced skin response in patients with psoriasis.

  1987cites this paper
• Polymorphonuclear leukocyte chemotaxis in systemic lupus erythematosus.

  1987cites this paper
• Determination of lysozyme activity by fluorescence polarization in rheumatoid synovial fluids and release of lysozyme from polymorphonuclear leukocytes by chemotactic factors.

  1987cites this paper
• A COMPARATIVE MOLECULAR STRUCTURAL STUDY OF THE THIRD COMPONENT OF COMPLEMENT AND ALPHA-2-MACROGLOBULIN: STRUCTURES OF THE PEPTIDE SEGMENTS THAT ARE SUSCEPTIBLE TO THE ATTACK BY ENDOPROTEINASES

  1987cites this paper
• Solution conformation of carboxy-terminal fragments of the third component of human complement C3: proton nuclear magnetic resonance study of C3a, des-Arg-C3a, and C3a Arg69.

  1987cites this paper
• Human monocyte adherence: a primary effect of chemotactic factors on the monocyte to stimulate adherence to human endothelium.

  1987cites this paper
• Neutrophil-mediated tumor cell destruction in cancer ascites. II. A OK-432 attracts killer neutrophils through activation of complement C5.

  1987cites this paper
• Surface receptor mobilization in complement-mediated neutrophil activation: characterization and effects of methylprednisolone.

  1987cites this paper
• Effect of low dose methotrexate on neutrophil chemotaxis induced by leukotriene B4 and complement C5a.

  1987cites this paper
• C5a-specific modulation of phagocyte functions in patients with localized bacterial infections.

  1987cites this paper
• Preparation and characterization of monoclonal antibodies against the fifth component of rabbit complement (C5).

  1987cites this paper
• Neutrophil-mediated pulmonary vascular injury. Synergistic effect of trace amounts of lipopolysaccharide and neutrophil stimuli on vascular permeability and neutrophil sequestration in the lung.

  1987cites this paper
• Failure of guinea pig plasma kallikrein to cause neutrophil migration

  1986cites this paper
• Neutrophil-mediated injury to endothelial cells. Enhancement by endotoxin and essential role of neutrophil elastase.

  1986cites this paper
• Mechanisms of inflammation and leukocyte chemotaxis in the rheumatic diseases.

  1986cites this paper
• Production of C5a antagonist by synovial and peritoneal tissue fibroblasts

  1986cites this paper
• Defects in monocyte chemotaxis in patients with neoplastic disease.

  1986cites this paper
• A simplified method for purification of human C5a from citrated plasma.

  1986cites this paper
• Airways hyperreactivity and inflammation produced by aerosolization of human C5A des arg.

  1986cites this paper