Three-Dimensional Structure of Herpes Simplex Virus from Cryo-Electron Tomography

No abstract is available for this paper.

• Publication year

  2003

• Venue

  Science

• Publication date

  2003-11-21

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1126/SCIENCE.1090284PMID 14631040
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• A Subpopulation of Tegument Protein vhs Localizes to Detergent-Insoluble Lipid Rafts in Herpes Simplex Virus-Infected Cells

  2003cited by this paper
• Prospects of electron cryotomography to visualize macromolecular complexes inside cellular compartments: implications of crowding.

  2002cited by this paper
• Break ins and break outs: viral interactions with the cytoskeleton of Mammalian cells.

  2002cited by this paper
• Herpesvirus Assembly and Egress

  2002cited by this paper
• Macromolecular Architecture in Eukaryotic Cells Visualized by Cryoelectron Tomography

  2002cited by this paper
• Egress of Alphaherpesviruses: Comparative Ultrastructural Study

  2001cited by this paper
• Noise reduction in electron tomographic reconstructions using nonlinear anisotropic diffusion.

  2001cited by this paper
• The UL6 Gene Product Forms the Portal for Entry of DNA into the Herpes Simplex Virus Capsid

  2001cited by this paper
• Electron Microscopy of Cells

  2001cited by this paper
• Herpes simplex virus glycoprotein D bound to the human receptor HveA.

  2001cited by this paper
• Herpes Simplex Virus Nucleocapsids Mature to Progeny Virions by an Envelopment → Deenvelopment → Reenvelopment Pathway

  2001cited by this paper
• Seeing the herpesvirus capsid at 8.5 A.

  2000cited by this paper
• Paxillin and focal adhesion signalling

  2000cited by this paper
• Three-dimensional structure of poliovirus receptor bound to poliovirus.

  2000cited by this paper
• Three classes of cell surface receptors for alphaherpesvirus entry.

  2000cited by this paper
• Isolation of Herpes Simplex Virus Procapsids from Cells Infected with a Protease-Deficient Mutant Virus

  2000cited by this paper
• Capsid Structure of Simian Cytomegalovirus from Cryoelectron Microscopy: Evidence for Tegument Attachment Sites

  1999cited by this paper
• Capsid Structure of Simian Cytomegalovirus from Cryoelectron Microscopy: Evidence for Tegument Attachment Sites

  1999cited by this paper
• Visualization of Tegument-Capsid Interactions and DNA in Intact Herpes Simplex Virus Type 1 Virions

  1999cited by this paper
• Structural biology of viruses

  1997cited by this paper
• Signaling through scaffold, anchoring, and adaptor proteins.

  1997cited by this paper
• Structure of the herpes simplex virus capsid. Molecular composition of the pentons and the triplexes.

  1993cited by this paper
• Liquid-crystalline, phage-like packing of encapsidated DNA in herpes simplex virus.

  1991cited by this paper
• Herpes simplex virus glycoproteins associated with different morphological entities projecting from the virion envelope.

  1987cited by this paper
• The Replication of Herpesviruses

  1974cited by this paper

• Cryogenic electron tomography reveals herpesvirus capsid assembly intermediates inside the cell nucleus.

  2026cites this paper
• Landscape expansion microscopy reveals interactions between membrane and phase-separated organelles

  2026cites this paper
• Development of Cancer Treatment Strategies Based on Virus‐Mimicking Nanoparticles

  2026cites this paper
• Bridging technical innovation and computational advances in studies of RNA-protein assemblies.

  2026cites this paper
• Cryoprotectants-assisted plunge freezing of thick brain tissue specimens for targeted physiologically relevant cryo-imaging in situ

  2025cites this paper
• The loss of both pUL16 and pUL21 in HSV-1-infected cells alters capsid–tegument composition, nuclear membrane architecture, cytoplasmic maturation and cell-to-cell spread

  2025cites this paper
• Applying 3D correlative structured illumination microscopy and X-ray tomography to characterise herpes simplex virus-1 morphogenesis

  2025cites this paper
• Landscape Expansion Microscopy Reveals Interactions between Membrane and Phase-Separated Organelles

  2025cites this paper
• Beyond Processing: Furin as a Central Hub in Viral Pathogenesis and Genetic Susceptibility

  2025cites this paper
• Deltaviruses spread through a viral Trojan Horse

  2025cites this paper
• Advances in viral vector-based delivery systems for gene therapy: a comprehensive review

  2025cites this paper
• Unique long 11 and 16 protein act as a bridge for the unique long 11, 16, 21 protein and glycoprotein E interaction in duck plague virus replication.

  2025cites this paper
• Discovery of Phloroglucinol Derivatives as a New Type of Nonnucleoside Inhibitors with Anti-herpes Simplex Virus Type 1 Activity.

  2025cites this paper
• The Triplex-Centric Assembly and Maturation of the Herpesvirus Procapsid

  2025cites this paper
• Investigation of the inhibitory activity of extracts, fractions and secondary metabolites of Silene spp. (Caryophylaceae) and Serratula cupuliformis (Asteraceae) on the «entry» of herpes simplex type 2 into sensitive cells of the Vero line

  2024cites this paper
• The loss of both pUL16 and pUL21 in HSV-1 infected cells abolishes cytoplasmic envelopment

  2024cites this paper
• ZMapp reduces diffusion of Ebola viral particles in fresh human cervicovaginal mucus

  2024cites this paper
• The incredible bulk: Human cytomegalovirus tegument architectures uncovered by AI-empowered cryo-EM

  2024cites this paper
• Optimizing encephalomyocarditis virus VP1 protein assembly on pseudorabies virus envelope via US9 protein anchoring

  2024cites this paper
• A Hitchhiker's Guide Through the Cell: The World According to the Capsids of Alphaherpesviruses.

  2024cites this paper
• Visualizing intermediate stages of viral membrane fusion by cryo-electron tomography.

  2024cites this paper
• Identification of a novel neurovirulence factor encoded by the cryptic orphan gene UL31.6 of herpes simplex virus 1

  2024cites this paper
• Structures of Epstein-Barr virus and Kaposi’s sarcoma-associated herpesvirus virions reveal species-specific tegument and envelope features

  2024cites this paper
• Bioinspired and bioengineered nucleic acid drug carriers

  2024cites this paper
• Architecture and Assembly of Structurally Complex Viruses.

  2024cites this paper
• A comprehensive overview on the crosstalk between microRNAs and viral pathogenesis and infection

  2024cites this paper
• Integrative Approaches to Study Virus Structures.

  2024cites this paper
• TomoNet: A streamlined cryogenic electron tomography software pipeline with automatic particle picking on flexible lattices

  2024cites this paper
• Cellular Processes Induced by HSV-1 Infections in Vestibular Neuritis

  2023cites this paper
• Cryo-electron tomography to study viral infection

  2023cites this paper
• Broadly neutralizing antibodies consistently trap HIV-1 in fresh cervicovaginal mucus from select individuals.

  2023cites this paper
• The role of nuclear pores and importins for herpes simplex virus infection.

  2023cites this paper
• Epstein‒Barr virus-associated cellular immunotherapy.

  2023cites this paper
• Cryo-electron tomography of viral infection - from applications to biosafety.

  2023cites this paper
• Three-dimensional nanoscale reduced-angle ptycho-tomographic imaging with deep learning (RAPID)

  2023cites this paper
• From the beginnings to multidimensional light and electron microscopy of virus morphogenesis.

  2023cites this paper
• When herpes simplex virus encephalitis meets antiviral innate immunity

  2023cites this paper
• In-vitro reconstitution of Herpes Simplex Virus 1 fusion identifies low pH as a fusion co-trigger

  2023cites this paper
• In Situ Imaging of Virus-Infected Cells by Cryo-Electron Tomography: An Overview.

  2023cites this paper
• In vitro reconstitution of herpes simplex virus 1 fusion identifies low pH as a fusion co-trigger

  2023cites this paper
• Electron Microscopy Studies of Soft Nanomaterials.

  2023cites this paper
• An intrinsic network of polar interactions is responsible for binding of UL49.5 C‐degron by the CRL2KLHDC3 ubiquitin ligase

  2023cites this paper
• Household dishwashing detergents efficiently inactivate HSV-1, but not the non-enveloped viruses HAV and MNV, while all viruses were removed from glass by manual scrubbing.

  2023cites this paper
• Novel inhibitors of HSV-1 protease effective in vitro and in vivo.

  2023cites this paper
• Towards application of CRISPR-Cas12a in the design of modern viral DNA detection tools (Review)

  2022cites this paper
• Hydrodynamics of spike proteins dictate a transport-affinity competition for SARS-CoV-2 and other enveloped viruses

  2022cites this paper
• Soft X-ray Tomography Reveals HSV-1-Induced Remodeling of Human B Cells

  2022cites this paper
• Three-dimensional insights into human enveloped viruses in vitro and in situ

  2022cites this paper
• Self-supervised learning for macromolecular structure classification based on cryo-electron tomograms

  2022cites this paper
• Cryo-electron tomography: The power of seeing the whole picture.

  2022cites this paper
• Cellular Chondroitin Sulfate and the Mucin-like Domain of Viral Glycoprotein C Promote Diffusion of Herpes Simplex Virus 1 While Heparan Sulfate Restricts Mobility

  2022cites this paper
• Herpesvirus‐Mimicking DNAzyme‐Loaded Nanoparticles as a Mitochondrial DNA Stress Inducer to Activate Innate Immunity for Tumor Therapy

  2022cites this paper
• Cryo-electron Tomography Remote Data Collection and Subtomogram Averaging.

  2022cites this paper
• Compressed sensing for electron cryotomography and high-resolution subtomogram averaging of biological specimens

  2022cites this paper
• Aspects of Biological Replication and Evolution Independent of the Central Dogma: Insights from Protein-Free Vesicular Transformations and Protein-Mediated Membrane Remodeling

  2022cites this paper
• Absence of the lectin-like domain of thrombomodulin reduces HSV-1 lethality of mice with increased microglia responses

  2022cites this paper
• Getting on the right track: Interactions between viruses and the cytoskeletal motor proteins

  2022cites this paper
• Mapping molecular complexes with super-resolution microscopy and single-particle analysis

  2022cites this paper
• Cryo-electron tomography: A long journey to the inner space of cells.

  2022cites this paper
• Virus-inspired nanosystems for drug delivery.

  2021cites this paper
• Nature-inspired dynamic gene-loaded nanoassemblies for the treatment of brain diseases.

  2021cites this paper
• Prophylactic and Therapeutic EBV Vaccines: Major Scientific Obstacles, Historical Progress, and Future Direction

  2021cites this paper
• Silver Nanoparticles as Potential Antiviral Agents

  2021cites this paper
• ICTV Virus Taxonomy Profile: Herpesviridae 2021

  2021cites this paper
• Domain Formation in Charged Polymer Vesicles

  2021cites this paper
• Challenges and triumphs in cryo-electron tomography

  2021cites this paper
• Physicochemical tools for studying virus interactions with targeted cell membranes in a molecular and spatiotemporally resolved context

  2021cites this paper
• The Hippocampal Vulnerability to Herpes Simplex Virus Type I Infection: Relevance to Alzheimer’s Disease and Memory Impairment

  2021cites this paper
• Ponderomotive forces in the system of two nanoparticles

  2021cites this paper
• Visualizing Trace Pollutants in Solids at Nanoscale via Electron Tomography.

  2021cites this paper
• Near-native state imaging by cryo-soft-X-ray tomography reveals remodelling of multiple cellular organelles during HSV-1 infection

  2021cites this paper
• Nanoparticles-Mediated Interventions to Prevent Herpes Simplex Virus (HSV) Entry into Susceptible Hosts

  2021cites this paper
• Stunning symmetries involved in the self-assembly of the HSV-1 capsid

  2021cites this paper
• Dot1l Aggravates Keratitis Induced by Herpes Simplex Virus Type 1 in Mice via p38 MAPK-Mediated Oxidative Stress

  2021cites this paper
• Physics of viral dynamics

  2021cites this paper
• Herpes Simplex Virus and Pattern Recognition Receptors: An Arms Race

  2021cites this paper
• A highly homogeneous polymer composed of tetrahedron-like monomers for high-isotropy expansion microscopy

  2021cites this paper
• Novel Cationic Meso-Arylporphyrins and Their Antiviral Activity against HSV-1

  2021cites this paper
• The Viral Capsid: A Master Key to Access the Host Nucleus

  2021cites this paper
• Herpes Simplex Viruses Type 1 and Type 2 Infection and Immunity

  2021cites this paper
• Assembly of infectious Kaposi’s sarcoma-associated herpesvirus progeny requires formation of a pORF19 pentamer

  2021cites this paper
• The promise and the challenges of cryo‐electron tomography

  2020cites this paper
• In situ structure of virus capsids within cell nuclei by correlative light and cryo-electron tomography

  2020cites this paper
• Structure of Epstein-Barr virus tegument protein complex BBRF2-BSRF1 reveals its potential role in viral envelopment

  2020cites this paper
• High resolution electron tomography and segmentation‐by‐modeling interpretation in Bsoft

  2020cites this paper
• Near-atomic cryo-electron microscopy structures of varicella-zoster virus capsids

  2020cites this paper
• Characterization of Nucleocytoplasmic Shuttling of Pseudorabies Virus Protein UL46

  2020cites this paper
• CryoEM structure of the tegumented capsid of Epstein-Barr virus

  2020cites this paper
• Biphasic exocytosis of herpesvirus from hippocampal neurons and mechanistic implication to membrane fusion

  2020cites this paper
• Role of Epstein-Barr Virus and Human Papillomavirus Coinfection in Cervical Cancer: Epidemiology, Mechanisms and Perspectives

  2020cites this paper
• Morphological and constituent viral-mimicking self-assembled nanoparticles promote cellular uptake and improve cancer therapeutic efficiency in vivo

  2020cites this paper
• The Interplay between Adeno-Associated Virus and Its Helper Viruses

  2020cites this paper
• Towards high-throughput in situ structural biology using electron cryotomography.

  2020cites this paper
• CryoEM structure of the tegumented capsid of Epstein-Barr virus

  2020cites this paper
• Cellular Electron Cryo-Tomography to Study Virus-Host Interactions.

  2020cites this paper
• The significance of gE domains of bovine herpes virus type 1 as revealed by high resolution electron microscopy

  2020cites this paper
• Caracterización molecular de las variantes del virus de Epstein-Barr detectadas en la cavidad oral de adolescentes de Cali, Colombia

  2020cites this paper
• Entry of Alphaherpesviruses.

  2020cites this paper
• Three‐dimensional organization of the cytoskeleton: A cryo‐electron tomography perspective

  2020cites this paper
• Simple, General Criterion for Onset of Disclination Disorder on Curved Surfaces.

  2020cites this paper