METABOLIC EFFECTS OF ALCOHOL ON THE LIVER.

No abstract is available for this paper.

• Publication year

  1964

• Venue

  New England Journal of Medicine

• Publication date

  1964-02-13

• Fields of study

  Medicine

• Identifiers
  DOI 10.1056/NEJM196402132700707PMID 14090958
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Studies on the alcohol's metabolism in patients with atrophic liver cirrhosis.

  2009cited by this paper
• Correlation of folate deficiency with alcoholism and associated macrocytosis, anemia, and liver disease.

  1963cited by this paper
• THE PREVENTION BY ADENOSINE TRIPHOSPHATE OF THE FATTY LIVER INDUCED BY ETHIONINE.

  1963cited by this paper
• The effect of prolonged alcohol treatment on the respiration of liver and brain mitochondria from male and female rats.

  1963cited by this paper
• Effect of triiodothyronine on rate of alcohol oxidation in dogs.

  1963cited by this paper
• Studies on the mechanism of ethanol-induced hypoglycemia.

  1963cited by this paper
• RECURRENT HYPOGLYCEMIA ASSOCIATED WITH ACUTE ALCOHOLISM.

  1963cited by this paper
• Ketone formation and inhibition of liver lipid synthesis by chylomicrons.

  1963cited by this paper
• ALTERATIONS IN HEPATIC LIPID BIOSYNTHETIC PATHWAYS AFTER ETHANOL, ETHIONINE AND CARBON TETRACHLORIDE.

  1963cited by this paper
• MECHANISM OF DEHYDRATION FOLLOWING ALCOHOL INGESTION.

  1963cited by this paper
• Hydrogen transfer in fatty acid synthesis by rat liver and mammarygland cell-free preparations studied with tritum-labeled pyridine nucleotides and glucose.

  1963cited by this paper
• Fatty Acid Ethyl Ester Formation During Ethanol Metabolism in vivo.

  1963cited by this paper
• The role of adenosine triphosphate deficiency in ethionine-induced inhibition of protein synthesis.

  1963cited by this paper
• LIVER DISEASE, HEPATIC ALCOHOL DEHYDROGENASE ACTIVITY, AND ALCOHOL METABOLISM IN THE HUMAN.

  1963cited by this paper
• ON THE BIOSYNTHESIS OF DIENOIC FATTY ACID BY ANIMAL TISSUES.

  1963cited by this paper
• ALCOHOL HYPOGLYCEMIA. I. CARBOHYDRATE METABOLISM OF PATIENTS WITH CLINICAL ALCOHOL HYPOGLYCEMIA AND THE EXPERIMENTAL REPRODUCTION OF THE SYNDROME WITH PURE ETHANOL.

  1963cited by this paper
• IN VITRO ASSAY FOR HUMAN INTRINSIC FACTOR.

  1963cited by this paper
• Increased susceptibility to pyelonephritis during acute hypertension by angiotensin II and norepinephrine.

  1963cited by this paper
• The utilization of ethanol. II. The alcohol-acetaldehyde dehydrogenase systems in the livers of alcohol-treated rats.

  1963cited by this paper
• Blood sugar and alcohol intoxication in the rat.

  1962cited by this paper
• Alterations of liver alcohol dehydrogenase and other hepatic enzymes in alcoholic cirrhosis.

  1962cited by this paper
• The development in the rat of fatty livers associated with reduced plasma-lipoprotein synthesis.

  1962cited by this paper
• Evaluation of tri-iodothyronine in the treatment of acute alcoholic intoxication.

  1962cited by this paper
• Ethanol induced hypoglycemia in oxythiamine treated animals.

  1962cited by this paper
• Hypomagnesaemia in chronic alcoholism.

  1962cited by this paper
• AN INTRACELLULAR DEFECT IN PROTEIN SYNTHESIS INDUCED BY CARBON TETRACHLORIDE

  1962cited by this paper
• Interrelation of uric acid and ethanol metabolism in man.

  1962cited by this paper
• Thyroid function in chronic alcoholism.

  1962cited by this paper
• Tryptophan and nicotinic acid metabolism in patients with cirrhosis of the liver.

  1962cited by this paper
• Effect of ethanol on plasma free fatty acids in man.

  1962cited by this paper
• Interference with secretion of triglycerides by the liver as a common factor in toxic liver injury with some observations on choline deficiency fatty liver.

  1962cited by this paper
• Ethanol metabolism and production of free acetate in the human liver.

  1962cited by this paper
• Studies on the pathogenesis of the ethanol-induced fatty liver. I. Synthesis and oxidation of fatty acids by the liver.

  1961cited by this paper
• Effect of ethanol and hydration on the urinary excretion of adrenaline and noradrenaline and on the blood sugar of rats.

  1961cited by this paper
• Alcohol and its relation to liver damage.

  1961cited by this paper
• Studies of biochemical changes in subcellular particles of rat liver and their relationship to a new hypothesis regarding the pathogenesis of carbon tetrachloride fat accumulation.

  1961cited by this paper
• The effect of ethanol on fatty acid metabolism; stimulation of hepatic fatty acid synthesis in vitro.

  1961cited by this paper
• Studies on the mechanism of the inhibition of galactose oxidation by ethanol.

  1961cited by this paper
• Production of hypoglycemia by Solox and by ethanol.

  1961cited by this paper
• Postalcoholic hypoglycemia and toxic hepatitis.

  1961cited by this paper
• Hypoglycemia and convulsions in children following alcohol ingestion.

  1961cited by this paper
• Alterations and mobilization of lipids in acute ethanol-treated rats.

  1961cited by this paper
• Observations on the effect of ethanol on the urinary excretion of histamine, 5-hydroxyindole acetic acid, catecholamines and 17-hydroxycorticosteroids in man.

  1961cited by this paper
• Ethionine administration in the rat. 1. Effects on the liver and plasma lipids and on the disposal of dietary fat.

  1961cited by this paper
• Characterization of Endogenous Ethanol in the Mammal

  1960cited by this paper
• A New Insight into Pathogenesis of Carbon Tetrachloride Fat Infiltration.∗

  1960cited by this paper
• Evidence for a defect in tryptophan metabolism in chronic alcoholism.

  1960cited by this paper
• Metabolites produced in the liver during alcohol oxidation.

  1960cited by this paper
• Depot fat as source of increased liver triglycerides after ethanol.

  1960cited by this paper
• Inhibitory Influence of Ethanol on Serotonin Metabolism

  1960cited by this paper
• A pilot study comparing the effects of pineal extract and a placebo in patients with chronic schizophrenia.

  1960cited by this paper
• Electrolyte disturbance in acute alcoholism: with particular reference to magnesium.

  1959cited by this paper
• Studies on severe alcohol intoxication in dogs. III. Effect of adrenalectomy.

  1959cited by this paper
• The rate of ethanol metabolism in fed and fasting animals.

  1959cited by this paper
• Disturbances of digestive physiology following acute drinking episodes in "skid-row" alcoholics.

  1959cited by this paper
• Metabolism and caloric value of alcohol.

  1959cited by this paper
• Glutamic dehydrogenase. II. The effect of various nucleotides on the association-dissociation and kinetic properties.

  1959cited by this paper
• Jaundice, hyperlipemia and hemolytic anemia: a heretofore unrecognized syndrome associated with alcoholic fatty liver and cirrhosis.

  1958cited by this paper
• Effect of acute ethanol intoxication on liver and plasma lipid fractions of the rat.

  1958cited by this paper
• The effect of ethyl alcohol on the secretion from the adrenal medulla in man.

  1958cited by this paper
• Effect of Acute Ethanol Intoxication on Liver and Plasma Lipid Fractions of the Rat

  1958cited by this paper
• Transport of fatty acids.

  1958cited by this paper
• Urinary epinephrine and levarterenol excretion during acute sublethal alcohol intoxication in dogs.

  1957cited by this paper
• Effect of adrenalectomy on ethanol and fat metabolism in the rat.

  1957cited by this paper
• Lactescence of serum following episodes of acute alcoholism and its probable relationship to acute pancreatitis.

  1957cited by this paper
• Rate of metabolism of ethanol in the mouse.

  1957cited by this paper
• Effect of Increased Diphosphopyridine Nucleotide Levels on Rate of Ethanol Metabolism in the Mouse

  1957cited by this paper
• Catalase Activity and Ethanol Metabolism in the Rat.∗

  1956cited by this paper
• The distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum.

  1955cited by this paper
• Effect of Chronic Ethanol Intoxication on Liver Lipid Content of Rats.∗

  1955cited by this paper
• Mechanism of Alcoholic Stimulation of Gastric Secretion.∗

  1955cited by this paper
• THE EFFECT OF ALCOHOL ON THE CHOLINE REQUIREMENT

  1954cited by this paper
• Alcohol diuresis.

  1951cited by this paper
• The effect of alcohol on the renal excretion of water and electrolyte.

  1950cited by this paper
• SPONTANEOUS HYPOGLYCEMIA IN SMOKE DRINKERS

  1941cited by this paper

• Current Understanding of Pathogenic Mechanisms and Disease Models of Citrin Deficiency

  2025cites this paper
• Magnesium Deficiency: The Insidious Executor of the Liver Disease.

  2024cites this paper
• Pioglitazone reverses alcohol-induced alterations in alveolar macrophage mitochondrial phenotype.

  2024cites this paper
• A critical review of recent knowledge of alcohol's effects on the immunological response in different tissues.

  2022cites this paper
• Spatiotemporal compartmentalization of hepatic NADH and NADPH metabolism

  2018cites this paper
• Advances in alcoholic liver disease: An update on alcoholic hepatitis.

  2015cites this paper
• Lomitapide and mipomersen: two first-in-class drugs for reducing low-density lipoprotein cholesterol in patients with homozygous familial hypercholesterolemia.

  2014cites this paper
• Modification of metabolic effects of ethanol by fructose.

  2009cites this paper
• Biodistribution of Radiolabeled Ethanol in Rodents

  2008cites this paper
• Hepatic Thyroid Hormone Levels Following Chronic Alcohol Consumption: Direct Experimental Evidence in Rats Against the Existence of a Hyperthyroid Hepatic State

  2007cites this paper
• Alcohol , malnutrition , and alcoholic cirrhosis 1

  2005cites this paper
• Cardiac Metabolism : Its Contributions to Alcoholic Heart Disease and Myocardial Failure

  2005cites this paper
• Alcoholic Heart Disease and Myocardial Failure

  2005cites this paper
• Changes in intestinal absorption of glucose in rats treated with ethanol

  2005cites this paper
• Cardiac Metabolism : Its Contributions to Alcoholic Heart Disease and Myocardial Failure

  2005cites this paper
• Effects of acute ethanol intoxication, chronic ethanol intoxication, and ethanol withdrawal on magnesium and calcium metabolism in the rat

  2004cites this paper
• 40 – Alcoholic Ketoacidosis

  2004cites this paper
• 39 – Alcohol Consumption and Diabetes Mellitus

  2004cites this paper
• Comparative analysis of hepatic ethanol metabolism in Fawn-Hooded and Wistar-Kyoto rats.

  2003cites this paper
• Universidade Federal do Rio Grande do Sul Faculdade de Odontologia Programa de Pós-Graduação em Odontologia QUANTIFICAÇÃO DAS AgNORs EM EPITÉLIO LINGUAL DE CAMUNDONGOS SUBMETIDOS À APLICAÇÃO TÓPICA E INGESTÃO DE ETANOL A 40° GL

  2003cites this paper
• Mitochondrial oxidative injury and energy metabolism alteration in rat fatty liver: Effect of the nutritional status

  2001cites this paper
• Behavior and drug measurements in Long-Evans and Sprague-Dawley rats after ethanol-cocaine exposure.

  1999cites this paper
• Rat hepatocytes isolated from alcohol‐induced fatty liver have an increased sensitivity to anoxic injury

  1997cites this paper
• Alcohols: Ethanol and Methanol

  1997cites this paper
• Advances in understanding mechanisms of birth defects : mechanistic understanding of human developmental toxicants

  1997cites this paper
• A perspective on acetaldehyde concentrations and toxicity in man and animals.

  1997cites this paper
• A Problem of Physical/Chemical Synthesis of Food Products on Planetary Bases

  1996cites this paper
• Alterations in glucose transporter proteins in alcoholic liver disease in the rat.

  1995cites this paper
• Ethanol inhibits asialoglycoprotein receptor synthesis but augments its mRNA expression in a human hepatoma cell line

  1994cites this paper
• Alcohol, glucose metabolism and diabetes.

  1993cites this paper
• Alcohol and the Liver

  1992cites this paper
• Kronik Alkoliklerde Serum ATP-Sitrat Liyaz Aktivitesi

  1992cites this paper
• Effect of ethanol administration on plasma glycerol levels in the rat.

  1992cites this paper
• Protracted metabolic acidosis: the impact of acute ethanol in hemorrhagic shock.

  1992cites this paper
• The effect of ethanol infusion on the altered glucose turnover during bacterial infection.

  1990cites this paper
• Metabolism Through Alcohol Dehydrogenase is Not a Prerequisite for Fatty Liver Induction by Alcohols

  1989cites this paper
• Ethanol administration diminishes the endotoxin-induced increase in glucose metabolism.

  1989cites this paper
• Alcoholic Ketoacidosis: A Case Report

  1987cites this paper
• ETHANOL AND LIVER INJURY: ASPECTS RELATING TO HEPATIC PROTEIN SYNTHESIS

  1987cites this paper
• Acute inhibition of hepatic lipase and increase in plasma lipoproteins after alcohol intake.

  1984cites this paper
• Dual defect in metabolism of very-low-density lipoprotein triglycerides. Patients with type 5 hyperlipoproteinemia.

  1984cites this paper
• Metabolic effects of moderate alcohol intake with meals in insulin-dependent diabetics controlled by artificial endocrine pancreas (AEP) and in normal subjects.

  1983cites this paper
• Metabolic tolerance as related to initial rates of ethanol metabolism.

  1982cites this paper
• Hepatic lipogenesis and mobilization of peripheral fats in the formation of alcoholic fatty liver.

  1981cites this paper
• Acute effects of ethanol intake on albumin and total protein synthesis in free and membrane-bound polyribosomes of rat liver.

  1981cites this paper
• Neurochemical Studies on the Metabolism and Effects of Catecholic Isoquinolines

  1981cites this paper
• Metabolism and Metabolic Effects of Ethanol

  1981cites this paper
• Lipid and Lipoprotein Abnormalities in Alcoholic Liver Disease

  1981cites this paper
• Cerebral Metabolic State During the Ethanol Withdrawal Reaction in the Rat

  1980cites this paper
• Lipid Metabolism and Its Disorders

  1980cites this paper
• Delirium tremens: Some clinico‐chemical features A STUDY OF ALANINE‐AMINOTRANSFERASE, ALCALINE PHOSPHATASE, PROTHROMBINE AND ENOLASE

  1980cites this paper
• Hazardous alcohol consumption and diseases of the circulatory system.

  1980cites this paper
• CEREBRAL BLOOD FLOW AND CEREBRAL METABLOLICSTATE DURING ABSTINENCE FOLLOOWING ETHANOL INTOXICATION IN RAT

  1980cites this paper
• Effects of chronic ethanol ingestion on glucose homeostasis in males and females.

  1980cites this paper
• 19 – EFFECTS OF ALCOHOL ON GASTROINTESTINAL AND PANCREATIC FUNCTION IN ALCOHOLICS

  1979cites this paper
• Drug Interactions With Alcohol

  1979cites this paper
• Alcoholism and cerebrovascular thrombosis in the young

  1979cites this paper
• Drugs, alcohol and malabsorption.

  1979cites this paper
• Amino Acids and Ethanol

  1979cites this paper
• Alcoholic ketoacidosis in a pregnant woman.

  1979cites this paper
• Alcohol, malnutrition, and alcoholic cirrhosis.

  1979cites this paper
• Effect of ethanol on lactic acid production by exercised normal muscle

  1978cites this paper
• Effect of drugs affecting microsomal enzymes on serum protein pattern and fat content of the liver

  1978cites this paper
• Alcohol and Human Behavior

  1978cites this paper
• Abnormal plasma lipoproteins and lecithin-cholesterol acyltransferase deficiency in alcoholic liver disease.

  1977cites this paper
• Effect of repeated doses of ATP on serum protein pattern and fat content of the liver in experimental diabetes

  1977cites this paper
• Effect of ethanol intake on the incorporation of labelled amino acids into liver protein.

  1976cites this paper
• The actions of avenaciolide and ethanol on glucose metabolism and on related enzyme activities in the isolated perfused rat liver.

  1976cites this paper
• Cardiovascular effects of severe liver disease

  1976cites this paper
• Multidisciplinary Conferences in Gastroenterology. Cardiovascular effects of severe liver disease.

  1976cites this paper
• Verhalten der Triglycerid-Fettsäuren bei fastenden und isokalorisch ernährten Versuchspersonen unter akuter Äthanolbelastung. Einfluß der Lipolysehemmung durch Nikotinsäure und Glucose

  1976cites this paper
• EFFECT OF MATERNAL ETHANOL CONSUMPTION ON FETAL HEPATIC METABOLISM IN THE RAT *

  1976cites this paper
• 23 – DRUG DEPENDENCE IN HOSPITALIZED PATIENTS

  1976cites this paper
• Turnover of Plasma Proteins

  1976cites this paper
• Hyperlipoproteinämie Typ IV

  1976cites this paper
• Mammalian liver alcohol dehydrogenases.

  1975cites this paper
• Effect of long-term administration of ethanol to the rat: lipids, collagen and other proteins, and Mallory bodies in the liver.

  1975cites this paper
• INTESTINAL FUNCTION IN CHRONIC ALCOHOLISM *

  1975cites this paper
• Alcohol and dietary factors in cirrhosis. An epidemiological study of 304 alcoholic patients.

  1975cites this paper
• Therapy of Alcoholic Liver Disease**Supported in part by the Stratfield Fund.

  1975cites this paper
• Incorporation of labelled amino acids into liver protein after acute ethanol administration.

  1975cites this paper
• The Effect of Ethanol on Albumin and Fibrinogen Synthesis In Vivo and in Hepatocyte Suspensions

  1975cites this paper
• Effects of a choline-deficient diet on the induction of drug- and ethanol-metabolizing enzymes and on the alteration of rates of ethanol degradation by ethanol and phenobarbital.

  1975cites this paper
• Studies in type I glycogenosis: the paradoxical effect of ethanol on lactate.

  1975cites this paper
• Immunosuppressive and cytotoxic drugs in dermatology.

  1974cites this paper
• The effect of acute ethanol ingestion on in vitro metabolism of choline and ethanol derivatives in rat liver.

  1974cites this paper
• Hyperlipidaemia as a complication of rifampicin treatment.

  1974cites this paper
• EFFECT OF ETHANOL ON THE OXIDATIVE METABOLISM OF TRYPTAMINE BY RAT LIVER HOMOGENATE

  1974cites this paper
• Acute pancreatitis with hyperlipemia. Evidence for a persistent defect in lipid metabolism.

  1974cites this paper
• The Effects of Halothane and Methoxyflurane Metabolites on Lipolysis In Vitro

  1974cites this paper
• The influence of force-feeding on the transport of plasma lipids in the chicken (Gallus gallus L.)

  1974cites this paper
• Hyperlipidemia and coronary artery disease. Prinicples of diet and drug treatment.

  1974cites this paper
• In vitro inhibition of protein synthesis in rat liver as a consequence of ethanol metabolism.

  1974cites this paper
• Psoriasis-liver-methotrexate interactions.

  1973cites this paper
• Effects of Ethanol on Liver Metabolism

  1973cites this paper
• The complications of alcoholism : an epidemiological, statistical and nutritional study on alcoholics admitted to a general hospital psychiatric unit

  1973cites this paper
• Changes in fatty acid composition of myocardial triglyceride following a single administration of ethanol to rabbits.

  1973cites this paper
• Pharmacokinetics of trichloroethanol and metabolites and interconversions among variously referenced pharmacokinetic parameters.

  1973cites this paper
• Type IV hyperlipoproteinaemia.

  1973cites this paper
• Central noradrenergic mechanism of acute and chronic ethanol with observations on the role of acetaldehyde

  1973cites this paper