Structure and expression of conserved Wnt pathway components in the demosponge Amphimedon queenslandica

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Evolution & Development

• Publication date

  2010-09-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1111/j.1525-142X.2010.00435.xPMID 20883218
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The Amphimedon queenslandica genome and the evolution of animal complexity

  2010cited by this paper
• Wnt signaling and induction in the sponge aquiferous system: evidence for an ancient origin of the organizer

  2010cited by this paper
• Phylogenomics revives traditional views on deep animal relationships.

  2009cited by this paper
• Assessing the root of bilaterian animals with scalable phylogenomic methods

  2009cited by this paper
• The dawn of developmental signaling in the metazoa.

  2009cited by this paper
• WNT/β-Catenin Signalling and Epithelial Patterning in the Homoscleromorph Sponge Oscarella

  2009cited by this paper
• Wnt/beta-catenin signaling: components, mechanisms, and diseases.

  2009cited by this paper
• The genome of the choanoflagellate Monosiga brevicollis and the origin of metazoans

  2008cited by this paper
• The transcription factor NF-κB in the demosponge Amphimedon queenslandica: insights on the evolutionary origin of the Rel homology domain

  2008cited by this paper
• A maternally localised Wnt ligand required for axial patterning in the cnidarian Clytia hemisphaerica

  2008cited by this paper
• Analysis of cell movement in amphimedon embryos by injection of fluorescent tracers.

  2008cited by this paper
• Wnt Signal Amplification via Activity, Cooperativity, and Regulation of Multiple Intracellular PPPSP Motifs in the Wnt Co-receptor LRP6*

  2008cited by this paper
• Planar cell polarity signaling: from fly development to human disease.

  2008cited by this paper
• Unexpectedly robust assembly of the Axin destruction complex regulates Wnt/Wg signaling in Drosophila as revealed by analysis in vivo.

  2008influential reference
• Whole-mount in situ hybridization in amphimedon.

  2008cited by this paper
• Genesis and expansion of metazoan transcription factor gene classes.

  2008cited by this paper
• Two functionally distinct Axin-like proteins regulate canonical Wnt signaling in C. elegans.

  2007cited by this paper
• SnapShot: Noncanonical Wnt Signaling Pathways.

  2007cited by this paper
• Sea Anemone Genome Reveals Ancestral Eumetazoan Gene Repertoire and Genomic Organization

  2007cited by this paper
• Wnt and TGF-β Expression in the Sponge Amphimedon queenslandica and the Origin of Metazoan Embryonic Patterning

  2007cited by this paper
• Adenomatous polyposis coli (APC) plays multiple roles in the intestinal and colorectal epithelia

  2007cited by this paper
• Asymmetric developmental potential along the animal-vegetal axis in the anthozoan cnidarian, Nematostella vectensis, is mediated by Dishevelled.

  2007cited by this paper
• Functional redundancy of GSK-3alpha and GSK-3beta in Wnt/beta-catenin signaling shown by using an allelic series of embryonic stem cell lines.

  2007cited by this paper
• Analysis of dishevelled localization and function in the early sea urchin embryo.

  2007cited by this paper
• The 'Marx' of Groucho on development and disease.

  2007cited by this paper
• Isolation and characterization of Wnt pathway‐related genes from Porifera

  2007influential reference
• Planar cell polarity signaling in vertebrates

  2007cited by this paper
• Wnt signaling in ovarian tumorigenesis

  2007cited by this paper
• Functional redundancy of GSK-3α and GSK-3β in wnt/β-catenin signaling shown by using an allelic series of embryonic stem cell lines

  2007cited by this paper
• The Wnt/beta-catenin signaling pathway as a target in drug discovery.

  2007cited by this paper
• The Wnt/β-Catenin Signaling Pathway as a Target in Drug Discovery

  2007cited by this paper
• Two Oppositely Localised Frizzled RNAs as Axis Determinants in a Cnidarian Embryo

  2007influential reference
• Wnt11/β-catenin signaling in both oocytes and early embryos acts through LRP6-mediated regulation of axin

  2006cited by this paper
• Wnt/beta-catenin signaling in development and disease.

  2006cited by this paper
• Wnts as ligands: processing, secretion and reception

  2006cited by this paper
• Wnt signaling: complexity at the surface

  2006cited by this paper
• The Genome of the Sea Urchin Strongylocentrotus purpuratus

  2006cited by this paper
• The canonical Wnt pathway in embryonic axis polarity.

  2006cited by this paper
• Wnt signaling in stem cells and lung cancer.

  2006cited by this paper
• Wnt signaling in hydroid development: formation of the primary body axis in embryogenesis and its subsequent patterning.

  2006cited by this paper
• Wnt Signaling: Multiple Pathways, Multiple Receptors, and Multiple Transcription Factors*

  2006cited by this paper
• Early evolution of animal cell signaling and adhesion genes

  2006influential reference
• A WNT of things to come: evolution of Wnt signaling and polarity in cnidarians.

  2006cited by this paper
• Developmental expression of transcription factor genes in a demosponge: insights into the origin of metazoan multicellularity

  2006cited by this paper
• Flying at the head of the pack: Wnt biology in Drosophila

  2006cited by this paper
• The Dictyostelium repertoire of seven transmembrane domain receptors.

  2006influential reference
• A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation

  2005cited by this paper
• Nuclear β‐catenin promotes non‐neural ectoderm and posterior cell fates in amphioxus embryos

  2005influential reference
• Casein kinase 1 γ couples Wnt receptor activation to cytoplasmic signal transduction

  2005cited by this paper
• The genome of the social amoeba Dictyostelium discoideum

  2005cited by this paper
• Unexpected complexity of the Wnt gene family in a sea anemone

  2005cited by this paper
• Embryogenesis and metamorphosis in a haplosclerid demosponge: gastrulation and transdifferentiation of larval ciliated cells to choanocytes

  2005cited by this paper
• Cell biology: Relays at the membrane

  2005influential reference
• Maternal wnt11 activates the canonical wnt signaling pathway required for axis formation in Xenopus embryos.

  2005cited by this paper
• Sponge Development and Antiquity of Animal Pattern Formation1

  2005cited by this paper
• The developmental biology of Dishevelled: an enigmatic protein governing cell fate and cell polarity

  2005cited by this paper
• ProtTest: selection of best-fit models of protein evolution

  2005influential reference
• Casein kinase 1 gamma couples Wnt receptor activation to cytoplasmic signal transduction.

  2005cited by this paper
• The evolution of metazoan axial properties

  2005cited by this paper
• β-catenin directly displaces Groucho/TLE repressors from Tcf/Lef in Wnt-mediated transcription activation

  2005cited by this paper
• Wnt and calcium signaling: beta-catenin-independent pathways.

  2005cited by this paper
• Plasmodium falciparum glycogen synthase kinase-3: molecular model, expression, intracellular localisation and selective inhibitors.

  2004cited by this paper
• PHYLIP (Phylogeny Inference Package)

  2004influential reference
• The Frizzled family: receptors for multiple signal transduction pathways

  2004cited by this paper
• The DIX Domain Protein Coiled-coil-DIX1 Inhibits c-Jun N-terminal Kinase Activation by Axin and Dishevelled through Distinct Mechanisms*

  2004cited by this paper
• A mechanism for Wnt coreceptor activation.

  2004cited by this paper
• Mechanism of phosphorylation-dependent binding of APC to beta-catenin and its role in beta-catenin degradation.

  2004influential reference
• Nuclear-cytoplasmic shuttling of Axin regulates subcellular localization of beta-catenin.

  2004influential reference
• Crystal structure of a beta-catenin/APC complex reveals a critical role for APC phosphorylation in APC function.

  2004cited by this paper
• The Wnt signaling pathway in development and disease.

  2004cited by this paper
• Wnt signals across the plasma membrane to activate the β-catenin pathway by forming oligomers containing its receptors, Frizzled and LRP

  2004cited by this paper
• WNT and beta-catenin signalling: diseases and therapies.

  2004cited by this paper
• Polarity factor ‘Frizzled’ in the demosponge Suberites domuncula: identification, expression and localization of the receptor in the epithelium/pinacoderm 1

  2003cited by this paper
• An ancient role for nuclear β-catenin in the evolution of axial polarity and germ layer segregation

  2003cited by this paper
• You Wnt some, you lose some: oncogenes in the Wnt signaling pathway.

  2003cited by this paper
• Frizzled signalling and cell polarisation in Drosophila and vertebrates

  2003cited by this paper
• Armadillo repeat proteins: beyond the animal kingdom.

  2003cited by this paper
• Wg/Wnt signal can be transmitted through arrow/LRP5,6 and Axin independently of Zw3/Gsk3beta activity.

  2003cited by this paper
• Crystal structure of a beta-catenin/axin complex suggests a mechanism for the beta-catenin destruction complex.

  2003cited by this paper
• Direct binding of the PDZ domain of Dishevelled to a conserved internal sequence in the C-terminal region of Frizzled.

  2003cited by this paper
• Wnt/Wingless signaling through β-catenin requires the function of both LRP/Arrow and frizzled classes of receptors

  2003cited by this paper
• MrBayes 3: Bayesian phylogenetic inference under mixed models

  2003influential reference
• Drosophila Apc1 and Apc2 regulate Wingless transduction throughout development.

  2002cited by this paper
• Control of -Catenin Phosphorylation/Degradation by a Dual-Kinase Mechanism

  2002influential reference
• Receptor-dependent and tyrosine phosphatase-mediated inhibition of GSK3 regulates cell fate choice.

  2002cited by this paper
• Asymmetric localization of frizzled and the determination of notch-dependent cell fate in the Drosophila eye.

  2002cited by this paper
• Loss of the β-catenin homologue aardvark causes ectopic stalk formation in Dictyostelium

  2002cited by this paper
• TCF: Lady Justice Casting the Final Verdict on the Outcome of Wnt Signalling

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• In vivo developmental stages in murine natural killer cell maturation

  2002cited by this paper
• The Axin-like protein PRY-1 is a negative regulator of a canonical Wnt pathway in C. elegans.

  2002cited by this paper
• Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism.

  2002cited by this paper
• Direct interaction of Frizzled‐1, ‐2, ‐4, and ‐7 with PDZ domains of PSD‐95

  2002cited by this paper
• Planar cell polarization: do the same mechanisms regulate Drosophila tissue polarity and vertebrate gastrulation?

  2002cited by this paper
• All Tcf HMG box transcription factors interact with Groucho-related co-repressors.

  2001influential reference
• Cytological Basis of Photoresponsive Behavior in a Sponge Larva

  2001cited by this paper
• The Wnts

  2001cited by this paper
• The divergent Caenorhabditis elegans beta-catenin proteins BAR-1, WRM-1 and HMP-2 make distinct protein interactions but retain functional redundancy in vivo.

  2001cited by this paper
• Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway.

  2001cited by this paper
• Molecular mechanisms of β‐catenin recognition by adenomatous polyposis coli revealed by the structure of an APC–β‐catenin complex

  2001cited by this paper
• LDL-receptor-related proteins in Wnt signal transduction

  2000cited by this paper

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• Evolutionary and Structural Assessment of the Human Secreted Frizzled-Related Protein (SFRP) Family

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• Targeting Wnt-driven metabolic adaptations in cancer: integrating glycolysis, glutaminolysis, IDO1-mediated immune evasion, and therapeutic delivery strategies

  2025cites this paper
• The origin and evolution of Wnt signalling

  2024cites this paper
• Combinatorial Wnt signaling landscape during brachiopod anteroposterior patterning

  2024cites this paper
• The logistics of Wnt production and delivery.

  2023cites this paper
• Characterization and expression analysis of β-catenin from Exopalaemon carinicauda (Holthuis, 1950) (Caridea, Palaemonidae) in embryonic development and immune response to bacteria

  2023cites this paper
• Cell polarity signalling at the birth of multicellularity: What can we learn from the first animals

  2022cites this paper
• Gene activation of metazoan Fox transcription factors at the onset of metamorphosis in the marine demosponge Amphimedon queenslandica

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• Sea anemone Frizzled receptors play partially redundant roles in oral-aboral axis patterning

  2022cites this paper
• The role of cnidarian developmental biology in unraveling axis formation and Wnt signaling.

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  2022cites this paper
• Distinct Frizzled receptors independently mediate endomesoderm specification and primary archenteron invagination during gastrulation in Nematostella.

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• Expression of Wnt and TGF-Beta Pathway Components during Whole-Body Regeneration from Cell Aggregates in Demosponge Halisarca dujardinii

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• The significance of sponges for comparative studies of developmental evolution

  2020cites this paper
• Are there systematic biases in RNA-seq data analysis? A case study for Amphimedon queenslandica sponge as a model object

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  2019cites this paper
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• Molecular signature of an ancient organizer regulated by Wnt/β-catenin signalling during primary body axis patterning in Hydra

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• Establishment of the Axial Polarity and Cell Fate in Metazoa via Canonical Wnt Signaling: New Insights from Sponges and Annelids

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  2015cites this paper
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