Evaluation of the immune benefits of two probiotic strains Bifidobacterium animalis ssp. lactis, BB-12® and Lactobacillus paracasei ssp. paracasei, L. casei 431® in an influenza vaccination model: a randomised, double-blind, placebo-controlled study.

No abstract is available for this paper.

• Publication year

  2012

• Venue

  British Journal of Nutrition

• Publication date

  2012-03-28

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1017/S000711451100420XPMID 21899798
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Randomised, double-blind and placebo-controlled study using new probiotic lactobacilli for strengthening the body immune defence against viral infections

  2011cited by this paper
• Probiotics-host communication

  2010cited by this paper
• Use of a fermented dairy probiotic drink containing Lactobacillus casei (DN-114 001) to decrease the rate of illness in kids: the DRINK study A patient-oriented, double-blind, cluster-randomized, placebo-controlled, clinical trial

  2010cited by this paper
• Plasmids encoding the mucosal chemokines CCL27 and CCL28 are effective adjuvants in eliciting antigen-specific immunity in vivo

  2010cited by this paper
• Guidance for substantiating the evidence for beneficial effects of probiotics: current status and recommendations for future research.

  2010cited by this paper
• The study to investigate the potential benefits of probiotics in yogurt, a patient-oriented, double-blind, cluster-randomised, placebo-controlled, clinical trial

  2010cited by this paper
• Lactobacillus GG in the prevention of gastrointestinal and respiratory tract infections in children who attend day care centers: a randomized, double-blind, placebo-controlled trial.

  2010cited by this paper
• Probiotic Effects on Cold and Influenza-Like Symptom Incidence and Duration in Children

  2009cited by this paper
• Use of probiotic bacteria as an adjuvant for an influenza vaccine.

  2009cited by this paper
• Probiotics, immune function, infection and inflammation: a review of the evidence from studies conducted in humans.

  2009cited by this paper
• Consumption of a fermented dairy product containing the probiotic Lactobacillus casei DN-114 001 reduces the duration of respiratory infections in the elderly in a randomised controlled trial

  2009cited by this paper
• A probiotic fermented dairy drink improves antibody response to influenza vaccination in the elderly in two randomised controlled trials.

  2009influential reference
• Challenging homeostasis to define biomarkers for nutrition related health.

  2009cited by this paper
• Oral administration of the probiotic Lactobacillus fermentum VRI-003 and mucosal immunity in endurance athletes

  2008cited by this paper
• Probiotic intervention has strain-specific anti-inflammatory effects in healthy adults.

  2008cited by this paper
• Salivary IgA as a risk factor for upper respiratory infections in elite professional athletes.

  2008cited by this paper
• Influenza virus host resistance model.

  2007cited by this paper
• Immunological parameters: what do they mean?

  2007cited by this paper
• Oral intake of Lactobacillus fermentum CECT5716 enhances the effects of influenza vaccination.

  2007influential reference
• Differentiation of memory B and T cells.

  2006cited by this paper
• Probiotic bacteria reduced duration and severity but not the incidence of common cold episodes in a double blind, randomized, controlled trial.

  2006cited by this paper
• Specific Probiotics in Enhancing Maturation of IgA Responses in Formula-Fed Infants

  2006cited by this paper
• Combined effect of different lactic acid bacteria strains on the mode of cytokines pattern expression in human peripheral blood mononuclear cells.

  2006cited by this paper
• Probiotic bacteria stimulate virus–specific neutralizing antibodies following a booster polio vaccination

  2005cited by this paper
• Increasing work-place healthiness with the probiotic Lactobacillus reuteri: A randomised, double-blind placebo-controlled study

  2005cited by this paper
• Markers to measure immunomodulation in human nutrition intervention studies

  2005cited by this paper
• Lactobacillus casei improves resistance to pneumococcal respiratory infection in malnourished mice.

  2005cited by this paper
• Influenza Virus: Immunity and Vaccination Strategies. Comparison of the Immune Response to Inactivated and Live, Attenuated Influenza Vaccines

  2004cited by this paper
• PASSCLAIM1—Gut health and immunity

  2004cited by this paper
• The humoral response to live and inactivated influenza vaccines administered alone and in combination to young adults and elderly.

  2002cited by this paper
• Effect of long term consumption of probiotic milk on infections in children attending day care centres: double blind, randomised trial

  2001cited by this paper
• Mucosal immune responses and risk of respiratory illness in elite athletes.

  2000cited by this paper
• Effect of a probiotic formula on intestinal immunoglobulin A production in healthy children.

  1998cited by this paper
• A rapid evaluation of phagocytosis and killing of Candida albicans by CD13+ leukocytes.

  1997cited by this paper
• Pneumococcal antibody responses in elite swimmers

  1996cited by this paper
• Immunomodulation of human blood cells following the ingestion of lactic acid bacteria.

  1995cited by this paper
• Progress in enzyme immunoassays: production of reagents, experimental design, and interpretation.

  1985cited by this paper
• A Simple Sequentially Rejective Multiple Test Procedure

  1979cited by this paper

• Heat-Killed Enterococcus faecalis EF-2001 Promotes Systemic Th1-Skewed Immune Activation Without Detectable Reduction of Influenza Viral Load in Mice.

  2026cites this paper
• Health benefits of Bifidobacterium animalis subsp. lactis BB-12 in infants and children: a mini-review.

  2026cites this paper
• Study protocol for a randomised controlled trial evaluating the efficacy of dietary modulation of probiotics on nutritional status and antibody response to SARS-CoV-2 in Indonesian adolescents: gut-lung axis (DIVINE)

  2025cites this paper
• Bifidobacterium animalis subsp. lactis modulates early‐life immune response and gut metabolism

  2025cites this paper
• Recent insights and advances in gut microbiota's influence on host antiviral immunity

  2025cites this paper
• Comparative effectiveness of oral nutritional supplements in preventing respiratory tract infections among adults: a systematic review and network meta-analysis

  2025cites this paper
• The resident gut microbiome modulates the effect of synbiotics on the immunogenicity after SARS-COV-2 vaccination in elderly and diabetes patients

  2025cites this paper
• The emerging role of the gut microbiota in vaccination responses

  2025cites this paper
• Tapioca-Resistant Maltodextrin Enhances Probiotic Survival More Effectively Than Commercial Prebiotics Under Simulated Gastrointestinal Conditions

  2025cites this paper
• Diet, microbiome, and probiotics establish a crucial link in vaccine efficacy

  2025cites this paper
• Comparative Genomics Analysis Combined with Homologous Overexpression Reveals the Mechanism of Species-Specific Acid Stress Resistance in Bifidobacterium animalis

  2025cites this paper
• Understanding the probiotic health benefits of Bifidobacterium animalis subsp. lactis, BB-12™

  2025cites this paper
• Subphenotypes of Long COVID and the clinical applications of probiotics.

  2025cites this paper
• Sustainable probiotic production via AI: medium optimization and metabolic mechanisms in Bifidobacterium animalis ssp. lactis BB-12 using agricultural waste.

  2025cites this paper
• Ascertaining the claims and reality of probiotic usage as an adjuvant therapy against virus-induced respiratory tract infections

  2025cites this paper
• Immunomodulatory Role of Milk on Gut Microbiota: Implications for Enhancing Oral Vaccine Efficacy.

  2025cites this paper
• Comparative effects of non-fermented and Lacticaseibacillus paracasei-fermented pomelo juice on gut microbiota composition and short-chain fatty acid production: An in vitro colonic model

  2024cites this paper
• Effect of probiotic administration to breastfeeding mothers with very low birthweight neonates on some neonatal and maternal outcomes: study protocol for a randomised, double-blind, placebo-controlled trial

  2024cites this paper
• Beer for live microbe delivery

  2024cites this paper
• Guía colombiana para el uso de probióticos en patologías pediátricas

  2024cites this paper
• The Influence of Probiotic Lactobacilli on COVID-19 and the Microbiota

  2024cites this paper
• Probiotic Potential and Enhanced Adhesion of Fermented Foods-Isolated Lactic Acid Bacteria to Intestinal Epithelial Caco-2 and HT-29 Cells

  2024cites this paper
• Exploring the associations between gut microbiota composition and SARS-CoV-2 inactivated vaccine response in mice with type 2 diabetes mellitus

  2024cites this paper
• Probiotics-Loaded Microspheres for Cosmetic Applications

  2024cites this paper
• Pediococcus pentosaceus MIANGUAN Enhances the Immune Response to Vaccination in Mice

  2024cites this paper
• The Prevention of Viral Infections: The Role of Intestinal Microbiota and Nutritional Factors

  2024cites this paper
• Ameliorating effects of Lactobacillus probiotics on cadmium-induced hepatotoxicity, inflammation, and oxidative stress in Wistar rats

  2024cites this paper
• The Trajectory of Successful Aging: Insights from Metagenome and Cytokine Profiling

  2024cites this paper
• The Effects of Dairy Consumption on Vaccine Immune Response and Immunoglobulins: A Systematic Literature Review

  2024cites this paper
• Lactobacilli in COVID-19: A Systematic Review Based on Next-Generation Sequencing Studies

  2024cites this paper
• Intestinal Microbiota and Its Effect on Vaccine-Induced Immune Amplification and Tolerance

  2024cites this paper
• Lactobacillus plantarum GUANKE modulate anti-viral function of dendritic cells in mice.

  2024cites this paper
• The Potential of Probiotics as Ingestible Adjuvants and Immune Modulators for Antiviral Immunity and Management of SARS-CoV-2 Infection and COVID-19

  2023cites this paper
• Overview of anti-viral effects of probiotics via immune cells in pre-, mid- and post-SARS-CoV2 era

  2023cites this paper
• Development of a novel multi-epitope oral DNA vaccine for rabies based on a food-borne microbial vector.

  2023cites this paper
• Effects of Glucosinolate-Enriched Red Radish (Raphanus sativus) on In Vitro Models of Intestinal Microbiota and Metabolic Syndrome-Related Functionalities

  2023cites this paper
• Nutraceuticals Prepared with Specific Strains of Probiotics for Supplementing Gut Microbiota in Hosts Allergic to Certain Foods or Their Additives

  2023cites this paper
• Dietary intervention with functional foods modulating gut microbiota for improving the efficacy of COVID-19 vaccines

  2023cites this paper
• Influence of Microbiota on Vaccine Effectiveness: “Is the Microbiota the Key to Vaccine-induced Responses?”

  2023cites this paper
• Antiobesity Effects of Lactobacillus paracasei Subsp. paracasei, L. casei 431 on High-Fat Diet-Induced Obese Rats

  2023cites this paper
• Healthy adults supplemented with a nutraceutical formulation containing Aloe vera gel, rosemary and Poria cocos enhances the effect of influenza vaccination in a randomized, triple-blind, placebo-controlled trial

  2023cites this paper
• Sheep’s Butter and Correspondent Buttermilk Produced with Sweet Cream and Cream Fermented by Aromatic Starter, Kefir and Probiotic Culture

  2023cites this paper
• Efficacy of Bifidobacterium longum alone or in multi-strain probiotic formulations during early life and beyond

  2023cites this paper
• Influence of biotic interventions on the immune response to vaccines in young and older adults.

  2023cites this paper
• Probiotic therapy, African fermented foods and food-derived bioactive peptides in the management of SARS-CoV-2 cases and other viral infections

  2023cites this paper
• Limosilactobacillus reuteri DSM 17938 supplementation and SARS-CoV-2 specific antibody response in healthy adults: a randomized, triple-blinded, placebo-controlled trial

  2023cites this paper
• Immunomodulatory Activity of Probiotics in Models of Bacterial Infections

  2023cites this paper
• Consumption of yogurt fermented with Lactobacillus delbrueckii ssp. bulgaricus OLL1073R-1 augments serum antibody titers against seasonal influenza vaccine in healthy adults

  2022cites this paper
• Role of Acacia catechu and Scutellaria baicalensis in Enhancing Immune Function Following Influenza Vaccination of Healthy Adults: A Randomized, Triple-Blind, Placebo-Controlled Clinical Trial.

  2022cites this paper
• Probiotics as multifaceted oral vaccines against colon cancer: A review

  2022cites this paper
• Impact of oral administration of single strain Lactococcus lactis spp. cremoris on immune responses to keyhole limpet hemocyanin immunization and gut microbiota: A randomized placebo-controlled trial in healthy volunteers

  2022cites this paper
• Probiotics and probiotic-based vaccines: A novel approach for improving vaccine efficacy

  2022cites this paper
• Bifidobacterium animalis subsp. lactis BB-12 Has Effect Against Obesity by Regulating Gut Microbiota in Two Phases in Human Microbiota-Associated Rats

  2022cites this paper
• Fermented food/beverage and health: current perspectives

  2022cites this paper
• Microbiota and the Response to Vaccines Against Respiratory Virus

  2022cites this paper
• Vaccines, adjuvants and key factors for mucosal immune response

  2022cites this paper
• Probiotics as a biotherapeutics for the management and prevention of respiratory tract diseases

  2022cites this paper
• Association between Recent Usage of Antibiotics and Immunogenicity within Six Months after COVID-19 Vaccination

  2022cites this paper
• A Combined Supplement of Probiotic Strains AP-32, bv-77, and CP-9 Increased Akkermansia mucinphila and Reduced Non-Esterified Fatty Acids and Energy Metabolism in HFD-Induced Obese Rats

  2022cites this paper
• Gut microbiota‐derived synbiotic formula (SIM01) as a novel adjuvant therapy for COVID‐19: An open‐label pilot study

  2022cites this paper
• Vaccines, Microbiota and Immunonutrition: Food for Thought

  2022cites this paper
• Gut microbiome and dietary fibre intake strongly associate with IgG function and maturation following SARS-CoV-2 mRNA vaccination

  2022cites this paper
• Pharmacological Efficacy of Probiotics in Respiratory Viral Infections: A Comprehensive Review

  2022cites this paper
• Oligosaccharide equine feed supplement, Immulix, has minor impact on vaccine responses in mice

  2022cites this paper
• Bifidobacterium spp. as functional foods: A review of current status, challenges, and strategies

  2022cites this paper
• Probiotic Bacteria as a Functional Delivery Vehicle for the Development of Live Oral Vaccines

  2021cites this paper
• Viral Infections, the Microbiome, and Probiotics

  2021cites this paper
• Updated Genome Sequence for the Probiotic Bacterium Bifidobacterium animalis subsp. lactis BB-12

  2021cites this paper
• Accomplishment of probiotics in human health pertaining to immunoregulation and disease control.

  2021cites this paper
• The Impact of Gut Microbiota on the Immune Response to Vaccination

  2021cites this paper
• The effect of probiotics on respiratory tract infection with special emphasis on COVID-19: Systemic review 2010–20

  2021cites this paper
• Brewer’s Spent Grain Enhanced the Recovery of Potential Probiotic Strains in Fermented Milk After Exposure to In Vitro-Simulated Gastrointestinal Conditions

  2021cites this paper
• Selection of Probiotics in the Prevention of Respiratory Tract Infections and Their Impact on Occupational Health: Scoping Review

  2021influential citation
• Bioactive compounds and probiotics–a ray of hope in COVID-19 management

  2021cites this paper
• Probiotic Effects against Virus Infections: New Weapons for an Old War

  2021influential citation
• Fructans with Varying Degree of Polymerization Enhance the Selective Growth of Bifidobacterium animalis subsp. lactis BB-12 in the Human Gut Microbiome In Vitro

  2021cites this paper
• The intestinal microbiota: determinants of resiliency?

  2021cites this paper
• Regulation divergences of Lactobacillus fermentum PCC and Lactobacillus paracasei 431 on penicillin-induced upper respiratory tract microbial dysbiosis in BALB/c mice.

  2021cites this paper
• The efficacy of probiotics on virus titres and antibody production in virus diseases: A systematic review on recent evidence for COVID-19 treatment

  2021cites this paper
• Single Strain Probiotic Bifidobacteria Approach in Health and Non-Health Fields

  2021cites this paper
• Immunomodulation by the Commensal Microbiome During Immune-Targeted Interventions: Focus on Cancer Immune Checkpoint Inhibitor Therapy and Vaccination

  2021cites this paper
• The in vitro antiviral activity of Lacticaseibacillus casei MCJ protein-based metabolites on bovine viral diarrhea virus

  2021cites this paper
• Influence of Different Prebiotics on Viability of Lactobacillus casei, Lactobacillus plantarum and Lactobacillus rhamnosus Encapsulated in Alginate Microcapsules

  2021cites this paper
• Probiotic infant cereal improves children's gut microbiota: Insights using the Simulator of Human Intestinal Microbial Ecosystem (SHIME®).

  2021cites this paper
• From the Role of Microbiota in Gut-Lung Axis to SARS-CoV-2 Pathogenesis

  2021cites this paper
• Obesidad, inmunidad y vacunación

  2021cites this paper
• Obesity, immunity and vaccination

  2021cites this paper
• In the Age of Viral Pandemic, Can Ingredients Inspired by Human Milk and Infant Nutrition Be Repurposed to Support the Immune System?

  2021cites this paper
• Gut Microbiota-targeted Interventions for Reducing the Incidence, Duration, and Severity of Respiratory Tract Infections in Healthy Non-elderly Adults

  2020cites this paper
• Effects of non-pharmacological interventions as vaccine adjuvants in humans: a systematic review and network meta-analysis

  2020cites this paper
• Effects of probiotics on salivary cytokines and immunoglobulines: a systematic review and meta-analysis on clinical trials

  2020cites this paper
• Potential Immunomodulatory Activity of a Selected Strain Bifidobacterium bifidum H3-R2 as Evidenced in vitro and in Immunosuppressed Mice

  2020cites this paper
• Nutrition, immunity and COVID-19

  2020cites this paper
• A Rapid Advice Guideline for the Prevention of Novel Coronavirus Through Nutritional Intervention

  2020cites this paper
• Bifidobacterium animalis subsp lactis HN019 presents antimicrobial potential against periodontopathogens and modulates the immunological response of oral mucosa in periodontitis patients

  2020cites this paper
• Preventive and Tumor-Suppressive Effects of Lactobacillus Paracasei X12 in Rat Model of Colorectal Cancer

  2020cites this paper
• Immune modulatory capacity of probiotic lactic acid bacteria and applications in vaccine development.

  2020cites this paper
• The probiotic Bifidobacterium in the management of Coronavirus: A theoretical basis

  2020cites this paper
• A Survey on the survival of Lactobacillus paracasei in fermented and non-fermented frozen soy dessert

  2019cites this paper
• Commercial Strains of Lactic Acid Bacteria with Health Benefits

  2019cites this paper