Deletion of the human beta-globin LCR 5'HS4 or 5'HS1 differentially affects beta-like globin gene expression in beta-YAC transgenic mice.

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Blood Cells, Molecules & Diseases

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 17433733PMCID PMC1934938
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Deletion of the core region of 5' HS2 of the mouse beta-globin locus control region reveals a distinct effect in comparison with human beta-globin transgenes.

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  2003cited by this paper
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  2003cited by this paper
• Looping and interaction between hypersensitive sites in the active beta-globin locus.

  2002cited by this paper
• Activation of the beta-like globin genes in transgenic mice is dependent on the presence of the beta-locus control region.

  2002cited by this paper
• Sensitive ribonuclease protection assay employing glycogen as a carrier and a single inactivation/precipitation step.

  2001cited by this paper
• The 5'HS4 core element of the human beta-globin locus control region is required for high-level globin gene expression in definitive but not in primitive erythropoiesis.

  2001cited by this paper
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  2001cited by this paper
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  2000cited by this paper
• The polyoma virus enhancer cannot substitute for DNase I core hypersensitive sites 2-4 in the human beta-globin LCR.

  1999cited by this paper
• Hypersensitive Site 2 Specifies a Unique Function within the Human β-Globin Locus Control Region To Stimulate Globin Gene Transcription

  1999cited by this paper
• Correct function of the locus control region may require passage through a nonerythroid cellular environment.

  1999cited by this paper
• Description and targeted deletion of 5' hypersensitive site 5 and 6 of the mouse beta-globin locus control region.

  1998cited by this paper
• Developmental Specificity of the Interaction between the Locus Control Region and Embryonic or Fetal Globin Genes in Transgenic Mice with an HS3 Core Deletion

  1998cited by this paper
• LCR-dependent gene expression in beta-globin YAC transgenics: detailed structural studies validate functional analysis even in the presence of fragmented YACs.

  1998cited by this paper
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  1998cited by this paper
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  1997cited by this paper
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  1996cited by this paper
• Heterochromatin effects on the frequency and duration of LCR-mediated gene transcription.

  1996cited by this paper
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  1995cited by this paper
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  1995cited by this paper
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  1995cited by this paper
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  1993cited by this paper
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  1993cited by this paper
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  1992cited by this paper
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  1992cited by this paper
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  1990cited by this paper
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  1990cited by this paper
• Detailed analysis of the site 3 region of the human beta‐globin dominant control region.

  1990cited by this paper
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  1990cited by this paper
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  1989cited by this paper
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  1989cited by this paper
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  1987cited by this paper
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• Identification of regulatory elements of human beta-like globin genes.

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• The "beta-like-globin" gene domain in human erythroid cells.

  1985cited by this paper
• Developmental regulation of a cloned adult beta-globin gene in transgenic mice.

  1985cited by this paper
• Erythroid‐specific expression of human beta‐globin genes in transgenic mice.

  1985cited by this paper

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