Structural and functional plasticity of the human brain in posttraumatic stress disorder.

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Progress in Brain Research

• Publication date

  Unknown publication date

• Fields of study

  Medicine, Psychology

• Identifiers
  DOI 10.1016/S0079-6123(07)67012-5PMID 18037014PMCID PMC3226705
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Functional neuroanatomical correlates of traumatic stress revisited 7 years later, this time with data.

  2025cited by this paper
• Cortisol, Dehydroepiandrosterone, and Estradiol Measured Over 24 Hours in Women With Childhood Sexual Abuse-Related Posttraumatic Stress Disorder

  2007influential reference
• Alterations in Stress Reactivity After Long‐Term Treatment with Paroxetine in Women with Posttraumatic Stress Disorder

  2006influential reference
• Hippocampal volume in chronic posttraumatic stress disorder (PTSD): MRI study using two different evaluation methods.

  2006cited by this paper
• Treatment of patients with substance use disorders

  2006cited by this paper
• Endogenous cortisol elevations are related to memory facilitation only in individuals who are emotionally aroused.

  2006cited by this paper
• Neuropsychological outcomes of army personnel following deployment to the Iraq war.

  2006cited by this paper
• The impact of the 1991 Gulf War on the mind and brain: findings from neuropsychological and neuroimaging research

  2006cited by this paper
• Hippocampal and amygdalar volumes in dissociative identity disorder.

  2006influential reference
• Prefrontal mechanisms in extinction of conditioned fear.

  2006cited by this paper
• Stress-induced cortisol elevations are associated with impaired delayed, but not immediate recall.

  2005cited by this paper
• Magnetic resonance imaging (MRI) measurement of hippocampal volume in posttraumatic stress disorder: a meta-analysis.

  2005cited by this paper
• Effects of phenytoin on memory, cognition and brain structure in post-traumatic stress disorder: a pilot study

  2005cited by this paper
• Bilateral hippocampal volume reduction in adults with post‐traumatic stress disorder: A meta‐analysis of structural MRI studies

  2005cited by this paper
• Smaller head of the hippocampus in Gulf War-related posttraumatic stress disorder.

  2005cited by this paper
• Cortisol-induced impairments of working memory require acute sympathetic activation.

  2005cited by this paper
• Saliva cortisol in posttraumatic stress disorder: a community epidemiologic study.

  2004cited by this paper
• Smaller hippocampal volume in Dutch police officers with posttraumatic stress disorder.

  2004cited by this paper
• Treatment of posttraumatic stress disorder with phenytoin: an open-label pilot study.

  2004influential reference
• Neural correlates of the classic color and emotional stroop in women with abuse-related posttraumatic stress disorder.

  2004influential reference
• Effects of glucocorticoids on declarative memory function in major depression.

  2004influential reference
• Deficits in Verbal Declarative Memory Function in Women With Childhood Sexual Abuse-Related Posttraumatic Stress Disorder

  2004influential reference
• Cortisol and catecholamines in posttraumatic stress disorder: an epidemiologic community study.

  2004cited by this paper
• Depression: a case of neuronal life and death?

  2004cited by this paper
• Positron emission tomographic imaging of neural correlates of a fear acquisition and extinction paradigm in women with childhood sexual-abuse-related post-traumatic stress disorder

  2004cited by this paper
• Hippocampal function in posttraumatic stress disorder

  2004cited by this paper
• Effects of dexamethasone on declarative memory function in posttraumatic stress disorder.

  2004cited by this paper
• Requirement of Hippocampal Neurogenesis for the Behavioral Effects of Antidepressants

  2003cited by this paper
• Does Stress Damage the Brain? Understanding Trauma-Related Disorders From a Mind-Body Perspective

  2003cited by this paper
• Long-term treatment with paroxetine increases verbal declarative memory and hippocampal volume in posttraumatic stress disorder.

  2003cited by this paper
• Magnetic resonance imaging of hippocampal and amygdala volume in women with childhood abuse and borderline personality disorder.

  2003influential reference
• Cortisol response to a cognitive stress challenge in posttraumatic stress disorder (PTSD) related to childhood abuse.

  2003influential reference
• Higher Cortisol Levels Following Exposure to Traumatic Reminders in Abuse-Related PTSD

  2003influential reference
• Neural correlates of declarative memory for emotionally valenced words in women with posttraumatic stress disorder related to early childhood sexual abuse.

  2003influential reference
• MRI and PET study of deficits in hippocampal structure and function in women with childhood sexual abuse and posttraumatic stress disorder.

  2003influential reference
• HPA axis and memory.

  2003cited by this paper
• Elevation of the cortisol-dehydroepiandrosterone ratio in drug-free depressed patients.

  2002cited by this paper
• Uses of DHEA in aging and other disease states.

  2002cited by this paper
• Attention, learning, and memory performances and intellectual resources in Vietnam veterans: PTSD and no disorder comparisons.

  2002cited by this paper
• Are the neural substrates of memory the final common pathway in posttraumatic stress disorder (PTSD)?

  2002cited by this paper
• Reduced hippocampal volume and total white matter volume in posttraumatic stress disorder.

  2002cited by this paper
• Acute modulation of aged human memory by pharmacological manipulation of glucocorticoids.

  2002cited by this paper
• Memory for extinction of conditioned fear is long-lasting and persists following spontaneous recovery.

  2002cited by this paper
• Childhood trauma associated with smaller hippocampal volume in women with major depression.

  2002cited by this paper
• Relationship of enhanced norepinephrine activity during memory consolidation to enhanced long-term memory in humans.

  2002cited by this paper
• Long-term, progressive hippocampal cell loss and dysfunction induced by early-life administration of corticotropin-releasing hormone reproduce the effects of early-life stress

  2001cited by this paper
• Attenuation of frontal asymmetry in pediatric posttraumatic stress disorder.

  2001cited by this paper
• The relationship between stress induced cortisol levels and memory differs between men and women.

  2001cited by this paper
• Efficacy and safety of paroxetine treatment for chronic PTSD: a fixed-dose, placebo-controlled study.

  2001cited by this paper
• Decreased hippocampal N-acetylaspartate in the absence of atrophy in posttraumatic stress disorder.

  2001cited by this paper
• A pilot longitudinal study of hippocampal volumes in pediatric maltreatment-related posttraumatic stress disorder.

  2001cited by this paper
• Regulation of adult neurogenesis by psychotropic drugs and stress.

  2001cited by this paper
• Paroxetine in the treatment of chronic posttraumatic stress disorder: results of a placebo-controlled, flexible-dosage trial.

  2001cited by this paper
• Glucocorticoid feedback sensitivity and adrenocortical responsiveness in posttraumatic stress disorder.

  2001cited by this paper
• Magnetic resonance imaging volumes of the hippocampus and the amygdala in women with borderline personality disorder and early traumatization.

  2000influential reference
• Elevated circulatory level of GABAA – antagonistic neurosteroids in patients with combat-related post-traumatic stress disorder

  2000cited by this paper
• Altered salivary dehydroepiandrosterone levels in major depression in adults.

  2000cited by this paper
• Acute cortisone administration impairs retrieval of long-term declarative memory in humans

  2000cited by this paper
• Pituitary-adrenal and autonomic responses to stress in women after sexual and physical abuse in childhood.

  2000cited by this paper
• Chronic Antidepressant Treatment Increases Neurogenesis in Adult Rat Hippocampus

  2000cited by this paper
• Glucocorticoids and the regulation of memory consolidation

  2000cited by this paper
• Development and preliminary psychometric properties of an instrument for the measurement of childhood trauma: The early trauma inventory

  2000cited by this paper
• Dehydroepiandrosterone sulfate (DHEAS) counteracts decremental effects of corticosterone on dentate gyrus LTP. Implications for depression.

  2000cited by this paper
• 1999 Curt P. Richter award. Glucocorticoids and the regulation of memory consolidation.

  2000cited by this paper
• Memory--a century of consolidation.

  2000cited by this paper
• Neural correlates of exposure to traumatic pictures and sound in Vietnam combat veterans with and without posttraumatic stress disorder: a positron emission tomography study.

  1999cited by this paper
• Dehydroepiandrosterone replacement in aging humans.

  1999cited by this paper
• Stress and cognition: are corticosteroids good or bad guys?

  1999cited by this paper
• Decreased memory performance in healthy humans induced by stress-level cortisol treatment.

  1999cited by this paper
• Glutamate and post-traumatic stress disorder: toward a psychobiology of dissociation.

  1999cited by this paper
• A.E. Bennett Research Award. Developmental traumatology. Part II: Brain development.

  1999cited by this paper
• The role of corticotropin-releasing factor in depression and anxiety disorders.

  1999cited by this paper
• Neural correlates of memories of childhood sexual abuse in women with and without posttraumatic stress disorder.

  1999cited by this paper
• Serial CSF corticotropin-releasing hormone levels and adrenocortical activity in combat veterans with posttraumatic stress disorder.

  1999cited by this paper
• Working memory is more sensitive than declarative memory to the acute effects of corticosteroids: a dose-response study in humans.

  1999cited by this paper
• In vivo proton magnetic resonance spectroscopy of the medial temporal lobes of subjects with combat‐related posttraumatic stress disorder

  1998cited by this paper
• Increased diurnal plasma concentrations of dehydroepiandrosterone in depressed patients.

  1998cited by this paper
• Stress hormones and brain aging: adding injury to insult?

  1998cited by this paper
• Measurement of Dissociative States with the Clinician-Administered Dissociative States Scale (CADSS)

  1998influential reference
• Experience-Induced Neurogenesis in the Senescent Dentate Gyrus

  1998cited by this paper
• The effects of stress on memory and the hippocampus throughout the life cycle: Implications for childhood development and aging

  1998cited by this paper
• Dehydroepiandrosterone (DHEA) and DHEA-sulfate (DHEAS) protect hippocampal neurons against excitatory amino acid-induced neurotoxicity.

  1998cited by this paper
• More hippocampal neurons in adult mice living in an enriched environment

  1997cited by this paper
• Stress-induced declarative memory impairment in healthy elderly subjects: relationship to cortisol reactivity.

  1997cited by this paper
• Dehydroepiandrosterone decreases behavioral despair in high- but not low-anxiety rats.

  1997cited by this paper
• Magnetic resonance imaging-based measurement of hippocampal volume in posttraumatic stress disorder related to childhood physical and sexual abuse--a preliminary report.

  1997cited by this paper
• Hippocampal volume in women victimized by childhood sexual abuse

  1997cited by this paper
• A molecular and cellular theory of depression.

  1997cited by this paper
• Activation of Glutamatergic Neurotransmission by Ketamine: A Novel Step in the Pathway from NMDA Receptor Blockade to Dopaminergic and Cognitive Disruptions Associated with the Prefrontal Cortex

  1997cited by this paper
• Elevated CSF corticotropin-releasing factor concentrations in posttraumatic stress disorder.

  1997cited by this paper
• Clinical characteristics of women with a history of childhood abuse: unhealed wounds.

  1997cited by this paper
• Handbook of dissociation: Theoretical, empirical, and clinical perspectives.

  1996cited by this paper
• Recent Developments in the Neurobiology of Dissociation

  1996cited by this paper
• Adrenal secretion during major depression in 8- to 16-year-olds, I. Altered diurnal rhythms in salivary cortisol and dehydroepiandrosterone (DHEA) at presentation

  1996cited by this paper
• Adrenal secretion and major depression in 8- to 16-year-olds, II. Influence of co-morbidity at presentation

  1996cited by this paper
• Why Stress Is Bad for Your Brain

  1996cited by this paper
• Searching for memory: The brain, the mind, and the past.

  1996cited by this paper
• Stress- and treatment-induced elevations of cortisol levels associated with impaired declarative memory in healthy adults.

  1996cited by this paper
• Cortisol regulation in posttraumatic stress disorder and major depression: a chronobiological analysis.

  1996cited by this paper
• Etiological factors in the development of posttraumatic stress disorder.

  1995cited by this paper

• Efficacy and Safety of the Neuroplastogen TSND-201 for the Treatment of PTSD: A Randomized Clinical Trial.

  2026cites this paper
• Everyday stress-induced neurobehavioral dysregulation: therapeutic targets for management with Neurexan

  2025cites this paper
• Functional Anatomy of the Structures of the Limbic System Involved in the Development of Neuropsychiatric Disorders: A Review

  2025cites this paper
• Emotion generation and regulation in premenstrual dysphoric disorder: dysregulation of large-scale brain networks across the menstrual cycle.

  2025cites this paper
• Hippocampal subfield and amygdala volumes are associated with difficulties in emotion regulation of depressed patients with a history of childhood maltreatment

  2025cites this paper
• Impact of Post-Traumatic Stress Disorder Duration on Volumetric and Microstructural Parameters of the Hippo-Campus, Amygdala, and Prefrontal Cortex: A Multiparametric Magnetic Resonance Imaging Study with Correlation Analysis

  2025cites this paper
• Trauma Burden Affected People with Multiple Sclerosis During SARS-CoV-2 Pandemic

  2025cites this paper
• Post-Stroke PTSD: The Protective Role of CCR5-Δ32 Polymorphism

  2025cites this paper
• PHYSIOLOGICAL MECHANISMS OF STRESS AND POST-TRAUMATIC STRESS DISORDER

  2024cites this paper
• Widowhood Shock, Family Reconstruction, and Mild Cognitive Impairment Among Older Adults: A Prospective Cohort Study

  2024cites this paper
• Physiological and genomic signatures of war and displacement: A comprehensive literature review and future directions.

  2024cites this paper
• [Effects of electroacupuncture at auricular points on excitability of glutamatergic neurons in the anterior cingulate cortex of posttraumatic stress disorder mice].

  2024cites this paper
• A Neuroanatomic and Pathophysiologic Framework for Novel Pharmacological Approaches to the Treatment of Post-traumatic Stress Disorder

  2024cites this paper
• Interpreting the meaning of changes in hippocampal volume associated with vestibular loss

  2023cites this paper
• Adaptive Reorganization of Neural Pathways for Continual Learning with Spiking Neural Networks

  2023cites this paper
• A prolonged stress rat model recapitulates some PTSD-like changes in sleep and neuronal connectivity

  2023cites this paper
• Detecting microstructural alterations of cerebral white matter associated with breast cancer and chemotherapy revealed by generalized q-sampling MRI

  2023cites this paper
• A First Exploration: Can Eye Movement Desensitization and Reprocessing Improve Cognition in Older Adults With Posttraumatic Stress Disorder?

  2023cites this paper
• Diverse therapeutic developments for post-traumatic stress disorder (PTSD) indicate common mechanisms of memory modulation.

  2022cites this paper
• Acute-stress-induced change in salience network coupling prospectively predicts post-trauma symptom development

  2022cites this paper
• Autonomic regulation during sleep in PTSD

  2022cites this paper
• Neural correlates of stress and leucocyte telomere length in patients with coronary artery disease.

  2022cites this paper
• Distinct neural activations correlate with maximization of reward magnitude versus frequency.

  2022cites this paper
• Activated cell-cycle CDK4/CyclinD1-pRB-E2F1 signaling pathway is involved in the apoptosis of dorsal raphe nucleus in the rat model of PTSD.

  2022cites this paper
• Post-traumatic Stress Disorder amongst Surgical Residents of Lahore

  2022cites this paper
• Structural brain features signaling trauma, PTSD, or resilience? A systematic exploration

  2022cites this paper
• Sleep deprivation altered encoding of basolateral amygdala on fear acquisition.

  2022cites this paper
• Prefrontal cortical circuits in anxiety and fear: an overview

  2022cites this paper
• The Role of Social Support in Coping with Psychological Trauma: An Integrated Biopsychosocial Model for Posttraumatic Stress Recovery

  2022cites this paper
• Astrocytes in Post-traumatic Stress Disorder

  2022cites this paper
• Impact of Music in Males and Females for Relief from Neurodegenerative Disorder Stress

  2022cites this paper
• Neurological disorders in an elderly cohort that experienced past stressful events: a retrospective-prospective study.

  2022cites this paper
• How Memory Switches Brain Responses of Patients with Post-traumatic Stress Disorder

  2021cites this paper
• RETRACTED: Exploration on the structure of college students’ optimism and development of questionnaire

  2021cites this paper
• Social support, neurocognition, and posttraumatic stress disorder: Findings from the Canadian Longitudinal Study on Aging

  2021cites this paper
• Physical Exercise as Treatment for PTSD: A Systematic Review and Meta-Analysis.

  2021cites this paper
• The influence of major depressive disorders on neurocognitive function among adults living with HIV/AIDS in a regional referral hospital in Dodoma, Tanzania

  2021cites this paper
• Impact of Stress on Human Body: A Review

  2021cites this paper
• Predisposing Variations in Fear-Related Brain Networks Prospectively Predict Fearful Feelings during the 2019 Coronavirus (COVID-19) Pandemic.

  2021cites this paper
• The Association between Widowhood and Cognitive Function among Chinese Elderly People: Do Gender and Widowhood Duration Make a Difference?

  2021cites this paper
• A unifying translational framework to advance treatment research for comorbid PTSD and substance use disorders.

  2021cites this paper
• TGF-β/Smad Signalling in Neurogenesis: Implications for Neuropsychiatric Diseases

  2021cites this paper
• Reduction of DNMT3a and RORA in the nucleus accumbens plays a causal role in post-traumatic stress disorder-like behavior: reversal by combinatorial epigenetic therapy

  2021cites this paper
• Rat models for low and high adaptive response to exercise differ for stress‐related memory and anxiety

  2021cites this paper
• Exposure Therapy for Post-Traumatic Stress Disorder: Factors of Limited Success and Possible Alternative Treatment

  2020cites this paper
• Proactive Interference in Posttraumatic Stress Disorder.

  2020cites this paper
• mRNA and microRNA profiles in the amygdala are relevant to Susceptible and Resilient mice induced by psychological stress

  2020cites this paper
• Multi-domain potential biomarkers for post-traumatic stress disorder (PTSD) severity in recent trauma survivors

  2020cites this paper
• Beneficial Effects of Yoga on Memory and Cognition Associated to Stress

  2020influential citation
• Sleep, a Governor of Morbidity in PTSD: A Systematic Review of Biological Markers in PTSD-Related Sleep Disturbances

  2020cites this paper
• Seven Properties of Self-Organization in the Human Brain

  2020cites this paper
• mRNA and microRNA Profiles in the Amygdala Are Relevant to Susceptibility and Resilience to Psychological Stress Induced in Mice

  2020cites this paper
• MRS Shows Regionally Increased Glutamate Levels among Patients with Exhaustion Syndrome Due to Occupational Stress.

  2020cites this paper
• What About the Camp Followers – and their Children?

  2020cites this paper
• mRNA and microRNA Profiles in the Amygdala Are Relevant to Susceptibility and Resilience to Psychological Stress Induced in Mice

  2020cites this paper
• Sex differences in the brains of capuchin monkeys (Sapajus [Cebus] apella)

  2020cites this paper
• NSS_A_260734 545..562

  2020cites this paper
• Dysregulation of inflammation, neurobiology, and cognitive function in PTSD: an integrative review

  2020cites this paper
• miR-132 Regulates PTSD-like Behaviors in Rats Following Single-Prolonged Stress Through Fragile X-Related Protein 1

  2020cites this paper
• Genomics and proteomics in brain complexity in relation to chemically induced posttraumatic stress disorder

  2020cites this paper
• Structural plasticity and molecular markers in hippocampus of male rats after acute stress.

  2020cites this paper
• Investigating the role of the amygdala orexin receptor 1 in memory acquisition and extinction in a rat model of PTSD.

  2020cites this paper
• Mast Cells in Gut and Brain and Their Potential Role as an Emerging Therapeutic Target for Neural Diseases

  2019cites this paper
• Theoretical Foundations to Guide Mindfulness Meditation: A Path to Wisdom

  2019cites this paper
• Neurobiología del trastorno de estrés postraumático

  2019cites this paper
• Multi-Domain Potential Biomarkers for Post Traumatic Stress Disorder (PTSD) Severity in Recent Trauma Survivors

  2019cites this paper
• Microglial cell hyper-ramification and neuronal dendritic spine loss in the hippocampus and medial prefrontal cortex in a mouse model of PTSD.

  2019cites this paper
• Dysregulation of miR‐142 results in anxiety‐like behaviors following single prolonged stress

  2019cites this paper
• Sexual Assault and Memory

  2019cites this paper
• Introductory Chapter: Psychological Trauma

  2019cites this paper
• Impacts of Gender-Based Violence and Harassment on Graduate Student Academic Functioning

  2019cites this paper
• Pulsed electromagnetic field attenuated PTSD-induced failure of conditioned fear extinction

  2019cites this paper
• Neurobehavioral moderators of post-traumatic stress disorder (PTSD) trajectories: study protocol of a prospective MRI study of recent trauma survivors

  2019cites this paper
• Inflammation and post‐traumatic stress disorder

  2019cites this paper
• Mathematical Modeling of Neurostimulation for Post-traumatic Stress Disorder: A Migration Towards Multiscale Modeling to Assess Neural Response to Transcranial Direct Current Stimulation Treatments

  2019cites this paper
• A model of amygdala function following plastic changes at specific synapses during extinction

  2019cites this paper
• Intimate partner violence, trauma, and mental health need among female community college students

  2018cites this paper
• Alter spontaneous activity in amygdala and vmPFC during fear consolidation following 24 h sleep deprivation

  2018cites this paper
• Functioning of the Core Neural Network in Fear and Extinction

  2018cites this paper
• Impact of Common Mental Health Disorders on Cognition: Depression and Posttraumatic Stress Disorder in Forensic Neuropsychology Context

  2018cites this paper
• Cognitive Flexibility Predicts PTSD Symptoms: Observational and Interventional Studies

  2018cites this paper
• Impact of Common Mental Health Disorders on Cognition: Depression and Posttraumatic Stress Disorder in Forensic Neuropsychology Context

  2018cites this paper
• Morphological effects of chronic administration of zidovudine on the intracranial auditory relay centers of adult Wistar rats

  2018cites this paper
• Effects of Yoga on Thalamic Gamma-Aminobutyric Acid, Mood and Depression: Analysis of Two Randomized Controlled Trials

  2018cites this paper
• MRI Shows that Exhaustion Syndrome Due to Chronic Occupational Stress is Associated with Partially Reversible Cerebral Changes

  2018cites this paper
• Bullying at Workplace and Brain-Imaging Correlates

  2018cites this paper
• Pharmacological evaluation of an alpha2C selective antagonist in an animal model of posttraumatic stress disorder

  2018cites this paper
• Stress in the Educational System as a Potential Source of Epigenetic Influences on Children's Development and Behavior

  2018cites this paper
• Stress influences the dynamics of hippocampal structural remodeling associated with fear memory extinction

  2018cites this paper
• Persistent Stress-Induced Neuroplastic Changes in the Locus Coeruleus/Norepinephrine System

  2018cites this paper
• Hypothalamic CNTF volume transmission shapes cortical noradrenergic excitability upon acute stress

  2018cites this paper
• Competing Constructivisms: The Negotiation of PTSD and Related Stigma Among Post-9/11 Veterans in New York City

  2018cites this paper
• Met and DRD 2 Taq 1 A polymorphisms interact to influence PTSD symptom severity : A preliminary investigation in a South African population

  2018cites this paper
• The Neuroscience of Resilience

  2018cites this paper
• From PTSD to dementia, can art therapy be useful for prevention and intervention?

  2018cites this paper
• Inflammatory markers and their possible effects on cognitive function in women with posttraumatic stress disorder.

  2018cites this paper
• Attentional Functions and Stress, Implications for ADHD

  2018cites this paper
• Grey matter density changes of structures involved in Posttraumatic Stress Disorder (PTSD) after recovery following Eye Movement Desensitization and Reprocessing (EMDR) therapy.

  2017cites this paper
• Translational Biomarker Research for Militarily Relevant Populations in Neurocognitive Diseases

  2017cites this paper
• Stress and the Dynamic Fear Memory: Synaptic–Cellular Bases and Their Implication for Psychiatry Disorders

  2017cites this paper