Targeted expression of the signaling molecule decapentaplegic induces pattern duplications and growth alterations in Drosophila wings.

No abstract is available for this paper.

• Publication year

  1994

• Venue

  EMBO Journal

• Publication date

  1994-10-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/j.1460-2075.1994.tb06768.xPMID 7925288PMCID PMC395378
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Compartment boundaries and the control of Drosopfiffa limb pattern by hedgehog protein

  1994cited by this paper
• Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord.

  1994cited by this paper
• Drosophila hedgehog acts as a morphogen in cellular patterning.

  1994cited by this paper
• The Drosophila segment polarity gene patched interacts with decapentaplegic in wing development.

  1994cited by this paper
• Bone morphogenetic proteins and a signalling pathway that controls patterning in the developing chick limb.

  1994cited by this paper
• Organization of wing formation and induction of a wing-patterning gene at the dorsal/ventral compartment boundary

  1994cited by this paper
• Hedgehog is a signaling protein with a key role in patterning Drosophila imaginal discs.

  1994cited by this paper
• Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity.

  1993cited by this paper
• FGF-4 and BMP-2 have opposite effects on limb growth

  1993cited by this paper
• Sonic hedgehog mediates the polarizing activity of the ZPA.

  1993cited by this paper
• Targeted gene expression as a means of altering cell fates and generating dominant phenotypes.

  1993cited by this paper
• Organizing activity of wingless protein in Drosophila.

  1993cited by this paper
• Control of cell pattern in the neural tube: regulation of cell differentiation by dorsalin-1, a novel TGF beta family member.

  1993cited by this paper
• Contrasting distributions of patched and hedgehog proteins in the Drosophila embryo.

  1993cited by this paper
• The segment polarity gene hedgehog is required for progression of the morphogenetic furrow in the developing Drosophila eye.

  1993cited by this paper
• An activity gradient of decapentaplegic is necessary for the specification of dorsal pattern elements in the Drosophila embryo.

  1993cited by this paper
• Axis specification in the developing Drosophila appendage: the role of wingless, decapentaplegic, and the homeobox gene aristaless.

  1993cited by this paper
• Molecular genetics of aristaless, a prd-type homeo box gene involved in the morphogenesis of proximal and distal pattern elements in a subset of appendages in Drosophila.

  1993cited by this paper
• Gene expression during imaginal disc regeneration detected using enhancer-sensitive P-elements.

  1993cited by this paper
• Structure and expression of hedgehog, a Drosophila segment-polarity gene required for cell-cell communication.

  1993cited by this paper
• Interaction between dorsal and ventral cells in the imaginal disc directs wing development in Drosophila.

  1993cited by this paper
• Dorso-ventral patterning in the neural tube.

  1993cited by this paper
• A functionally conserved homolog of the Drosophila segment polarity gene hh is expressed in tissues with polarizing activity in zebrafish embryos.

  1993cited by this paper
• The Genome of Drosophila Melanogaster

  1992cited by this paper
• Decapentaplegic acts as a morphogen to organize dorsal-ventral pattern in the Drosophila embryo.

  1992cited by this paper
• Secretion and localized transcription suggest a role in positional signaling for products of the segmentation gene hedgehog.

  1992cited by this paper
• Molecular organization and embryonic expression of the hedgehog gene involved in cell-cell communication in segmental patterning of Drosophila.

  1992cited by this paper
• Boundaries and fields in early embryos.

  1992cited by this paper
• The Drosophila hedgehog gene is expressed specifically in posterior compartment cells and is a target of engrailed regulation.

  1992cited by this paper
• Secretion and movement of wingless protein in the epidermis of the Drosophila embryo.

  1991cited by this paper
• An extensive 3' cis-regulatory region directs the imaginal disk expression of decapentaplegic, a member of the TGF-beta family in Drosophila.

  1991cited by this paper
• The relationship of decapentaplegic and engrailed expression in Drosophila imaginal disks: do these genes mark the anterior-posterior compartment boundary?

  1991cited by this paper
• Retinoids, homeoboxes, and growth factors: toward molecular models for limb development.

  1991cited by this paper
• Unrestricted expression of the Drosophila gene patched allows a normal segment polarity

  1991cited by this paper
• Roles of wingless in patterning the larval epidermis of Drosophila.

  1991cited by this paper
• Pattern-specific expression of the Drosophila decapentaplegic gene in imaginal disks is regulated by 3' cis-regulatory elements.

  1990cited by this paper
• The Drosophila segment polarity gene patched is involved in a position-signalling mechanism in imaginal discs.

  1990cited by this paper
• Wing formation in Drosophila melanogaster requires decapentaplegic gene function along the anterior-posterior compartment boundary.

  1990cited by this paper
• The Drosophila patched gene encodes a putative membrane protein required for segmental patterning.

  1989cited by this paper
• A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback

  1989cited by this paper
• Distribution of the wingless gene product in Drosophila embryos: a protein involved in cell-cell communication.

  1989cited by this paper
• A protein with several possible membrane-spanning domains encoded by the Drosophila segment polarity gene patched

  1989cited by this paper
• The decapentaplegic gene: a TGF-beta homologue controlling pattern formation in Drosophila.

  1989cited by this paper
• Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase.

  1988cited by this paper
• Localized cell death caused by mutations in a Drosophila gene coding for a transforming growth factor-beta homolog.

  1988cited by this paper
• The segment polarity gene costal-2 in Drosophila. I. The organization of both primary and secondary embryonic fields may be affected.

  1987cited by this paper
• A transcript from a Drosophila pattern gene predicts a protein homologous to the transforming growth factor-β family

  1987cited by this paper
• The segment polarity gene costal-2 in Drosophila. II. The origin of imaginal pattern duplications.

  1987cited by this paper
• Drosophila: A practical approach : Edited by D.B. Roberts IRL Press; Oxford, Washington DC, 1986 xix + 295 pages. Paperback £16.50/$30, hardback £26/$47

  1987cited by this paper
• Parasegments and compartments in the Drosophila embryo

  1985cited by this paper
• Cell determination boundaries as organizing regions for secondary embryonic fields.

  1983cited by this paper
• Decapentaplegic: a gene complex affecting morphogenesis in Drosophila melanogaster.

  1982cited by this paper
• Compartments in the wing of Drosophila: a study of the engrailed gene.

  1976cited by this paper
• Clonal analysis of a genetically caused duplication of the anterior wing in Drosophila melanogaster.

  1976cited by this paper
• Positional signalling and specification of digits in chick limb morphogenesis

  1975cited by this paper
• Compartments and polyclones in insect development.

  1975cited by this paper
• Developmental analysis of the wing disc in the mutant engrailed of Drosophila melanogaster.

  1972cited by this paper
• Positional information and the spatial pattern of cellular differentiation.

  1969cited by this paper
• Embryonic Development and Induction

  1938cited by this paper

• Control of mitochondrial dynamics by the metabolic regulator dPGC1 limits Yorkie-induced oncogenic growth in Drosophila

  2025cites this paper
• Characteristic and functional study of intersex, a gene involved in sexual development in Gryllus bimaculatus

  2025cites this paper
• Regulation of Drosophila brain development and organ growth by the Minibrain/Rala signaling network

  2024cites this paper
• Regulation of brain development by the Minibrain/Rala signaling network

  2024cites this paper
• ERK inhibits Cic repressor function via multisite phosphorylation

  2024cites this paper
• The multimodal action of G alpha q in coordinating growth and homeostasis in the Drosophila wing imaginal disc

  2023cites this paper
• Heterodimerization-dependent secretion of bone morphogenetic proteins in Drosophila.

  2023cites this paper
• Is Drosophila Dpp/BMP morphogen spreading required for wing patterning and growth?

  2023cites this paper
• Smoothened antagonist sonidegib affects the development of D. melanogaster larvae via suppression of epidermis formation.

  2023cites this paper
• TnaA, a trithorax group protein, modulates wingless expression in different regions of the Drosophila wing imaginal disc

  2023cites this paper
• A comprehensive Drosophila resource to identify key functional interactions between SARS-CoV-2 factors and host proteins

  2023cites this paper
• Drosophila hedgehog signaling range and robustness depend on direct and sustained heparan sulfate interactions

  2023cites this paper
• Patterning of the Drosophila retina by the morphogenetic furrow

  2023cites this paper
• Ihog proteins contribute to integrin-mediated focal adhesions

  2022influential citation
• Roles of ZnT86D in Neurodevelopment and Pathogenesis of Alzheimer Disease in a Drosophila melanogaster Model

  2022cites this paper
• Predictive model for cytoneme guidance in Hedgehog signaling based on Ihog- Glypicans interaction

  2022cites this paper
• The wing imaginal disc

  2022cites this paper
• Drosophila hemocytes recognize lymph gland tumors of mxc mutants and activate the innate immune pathway in a reactive oxygen species-dependent manner

  2022cites this paper
• Heterodimerization-dependent secretion of BMPs in Drosophila

  2022cites this paper
• Roles of Drosophila fatty acid-binding protein in development and behavior.

  2022cites this paper
• Balancing competing effects of tissue growth and cytoskeletal regulation during Drosophila wing disc development

  2022cites this paper
• Regulated delivery controls Drosophila Hedgehog, Wingless, and Decapentaplegic signaling

  2021cites this paper
• Drosophila hemocytes recognize lymph gland tumors of mxc mutants and activate the Toll pathway in reactive oxygen species-dependent manner

  2021cites this paper
• Phenotypical and genetical characterization of the Mad1-2 allele during Drosophila wing development.

  2021cites this paper
• Glypicans define unique roles for the Hedgehog co-receptors boi and ihog in cytoneme-mediated gradient formation

  2021cites this paper
• Reduction of nucleolar NOC1 accumulates pre-rRNAs and induces Xrp1 affecting growth and resulting in cell competition in Drosophila

  2021cites this paper
• Transgenic Drosophila lines for LexA-dependent gene and growth regulation

  2021cites this paper
• A unified mechanism for the control of Drosophila wing growth by the morphogens Decapentaplegic and Wingless

  2021cites this paper
• The GTPase Rab8 differentially controls the long- and short-range activity of the Hedgehog morphogen gradient by regulating Hedgehog apico-basal distribution

  2021cites this paper
• Elevation of major constitutive heat shock proteins is heat shock factor independent and essential for establishment and growth of Lgl loss and Yorkie gain-mediated tumors in Drosophila

  2021cites this paper
• DAnkrd49 and Bdbt act via Casein kinase Ii to regulate planar polarity in Drosophila

  2020cites this paper
• Temporal flexibility of gene regulatory network underlies a novel wing pattern in flies

  2020cites this paper
• Control of Drosophila wing size by morphogen range and hormonal gating

  2020cites this paper
• Regulation of Anisotropic Tissue Growth by Two Orthogonal Signaling Centers.

  2020cites this paper
• Activation-induced substrate engagement in ERK signaling

  2020cites this paper
• Glypicans specifically regulate Hedgehog signaling through their interaction with Ihog in cytonemes

  2020cites this paper
• Regulated delivery controls Drosophila Hedgehog, Wingless and Decapentaplegic signaling

  2020cites this paper
• Multiscale Models Coupling Chemical Signaling and Mechanical Properties for Studying Tissue Growth

  2020cites this paper
• DAnkrd49 and Bdbt act via Casein kinase Iε to regulate planar polarity in Drosophila

  2020cites this paper
• A Nucleolar Isoform of the Drosophila Ubiquitin Specific Protease dUSP36 Regulates MYC-Dependent Cell Growth

  2020cites this paper
• Hh signaling from de novo organizers drive lgl neoplasia in Drosophila epithelium.

  2020cites this paper
• Airinemes: thin cellular protrusions mediate long-distance signalling guided by macrophages

  2020cites this paper
• Polarized sorting of Patched enables cytoneme‐mediated Hedgehog reception in the Drosophila wing disc

  2020cites this paper
• Activated Ras/JNK driven Dilp8 in imaginal discs adversely affects organismal homeostasis during early pupal stage in Drosophila, a new checkpoint for development

  2019cites this paper
• Drosophila jumu modulates apoptosis via a JNK-dependent pathway and is required for other processes in wing development

  2019cites this paper
• The miRNA bantam regulates growth and tumorigenesis by repressing the cell cycle regulator tribbles

  2019cites this paper
• Decoding Calcium Signaling Dynamics during Drosophila Wing Disc Development.

  2019cites this paper
• Ion Channel Contributions to Wing Development in Drosophila melanogaster

  2019cites this paper
• The genes expression difference between winged and wingless bird cherry-oat aphid Rhopalosiphum padi based on transcriptomic data

  2019cites this paper
• Drosophila models of pathogenic copy-number variant genes show global and non-neuronal defects during development

  2019cites this paper
• Genetic analysis of the RNA polymerase II CTD in Drosophila.

  2019cites this paper
• Single cell transcriptomic landscapes of pattern formation, proliferation and growth in Drosophila wing imaginal discs

  2019cites this paper
• Decapentaplegic function in wing vein development and wing morph transformation in brown planthopper, Nilaparvata lugens.

  2019cites this paper
• Understanding the mechanisms behind BMP-mediated growth in Drosophila wing precursors

  2019cites this paper
• Anchor negatively regulates BMP signalling to control Drosophila wing development.

  2018cites this paper
• Chondroitin sulfate proteoglycan Windpipe modulates Hedgehog signaling in Drosophila

  2018influential citation
• Yorkie and JNK Control Tumorigenesis in Drosophila Cells with Cytokinesis Failure.

  2018cites this paper
• Hedgehog reciprocally controls trafficking of Smo and Ptc through the Smurf family of E3 ubiquitin ligases

  2018cites this paper
• The role of the trithorax group TnaA isoforms in Hox gene expression, and in Drosophila late development

  2018cites this paper
• Synaptojanin regulates Hedgehog signalling by modulating phosphatidylinositol 4-phosphate levels

  2018cites this paper
• The Drosophila homologue of MEGF8 is essential for early development

  2018cites this paper
• Regulation of Smoothened ubiquitylation and cell surface expression through a Cul4–DDB1–Gβ E3 ubiquitin ligase complex

  2018cites this paper
• Oncogenic cooperation between Yorkie and the conserved microRNA miR-8 in the wing disc of Drosophila

  2018cites this paper
• The Stromal Niche for Epithelial Stem Cells: A Template for Regeneration and a Brake on Malignancy.

  2017cites this paper
• Growth and size control during development

  2017cites this paper
• In vivo relevance of intercellular calcium signaling in Drosophila wing development

  2017cites this paper
• Inwardly rectifying potassium channels influence Drosophila wing morphogenesis by regulating Dpp release

  2017cites this paper
• Investigating the Role of Dispatched in Hedgehog Ligand Transport and Delivery

  2017cites this paper
• Hedgehog signalling is required for cell survival in Drosophila wing pouch cells

  2017cites this paper
• Cytoneme-mediated cell-cell contacts for Hedgehog reception

  2017cites this paper
• TGF-β Family Signaling in Drosophila.

  2017cites this paper
• In vivo screening reveals interactions between Drosophila Manf and genes involved in the mitochondria and the ubiquinone synthesis pathway

  2017cites this paper
• Critical Point in Self-Organized Tissue Growth.

  2017cites this paper
• Identification of Drosophila Zfh2 as a Mediator of Hypercapnic Immune Regulation by a Genome-Wide RNA Interference Screen

  2016cites this paper
• Anchor negatively regulates BMP signaling to control Drosophila wing development

  2016cites this paper
• Nanobodies as novel tools to study morphogen function "in vivo"

  2016influential citation
• Evolutionarily Conserved Role of G-Protein-Coupled Receptor Kinases in the Hedgehog Signaling Pathway

  2016cites this paper
• Regulated protein depletion by the auxin-inducible degradation system in Drosophila melanogaster

  2016cites this paper
• High JNK following Ras/Rpr/Tak1 over-expression in imaginal discs of Drosophila reduces post-pupariation ecdysone via Dilp8 resulting in early pupal death

  2016influential citation
• Minibrain and Wings apart control organ growth and tissue patterning through down-regulation of Capicua

  2016cites this paper
• The legacy of Drosophila imaginal discs

  2016cites this paper
• BMP morphogen gradients in flies.

  2016cites this paper
• Comparative developmental analysis of Drosophila and Tribolium reveals conserved and diverged roles of abrupt in insect wing evolution.

  2016cites this paper
• Title : Anchor negatively regulates BMP signaling to control Drosophila wing 1 development 2 Running title : A novel gene anchor

  2016cites this paper
• Exploring the Conserved Role of MANF in the Unfolded Protein Response in Drosophila melanogaster

  2016influential citation
• Ecdysone promotes growth of imaginal discs through the regulation of Thor in D. melanogaster

  2015cites this paper
• Critical role for Fat/Hippo and IIS/Akt pathways downstream of Ultrabithorax during haltere specification in Drosophila.

  2015cites this paper
• A phyletic perspective on cell growth.

  2015cites this paper
• Local overexpression of Su(H)-MAPK variants affects Notch target gene expression and adult phenotypes in Drosophila

  2015cites this paper
• Phenotype-based clustering of glycosylation-related genes by RNAi-mediated gene silencing

  2015cites this paper
• Gliolectin positively regulates Notch signalling during wing-vein specification in Drosophila.

  2015cites this paper
• A large-scale, in vivo transcription factor screen defines bivalent chromatin as a key property of regulatory factors mediating Drosophila wing development

  2015cites this paper
• Organ Size Control: Lessons from Drosophila.

  2015cites this paper
• Dpp spreading is required for medial but not for lateral wing disc growth

  2015cites this paper
• Visualization of cell-to-cell communication by advanced microscopy techniques

  2015cites this paper
• Coordination of patterning and growth by the morphogen DPP.

  2014cites this paper
• Dynamics of the core planar polarity proteins and their role in morphogenesis in Drosophila

  2014cites this paper
• Analyse von Wechselwirkungen der Homeodomäninteragierenden Proteinkinase (Hipk) in Drosophila melanogaster unter besonderer Berücksichtigung des Interaktionspartners Spenito (Nito)

  2014cites this paper
• Rabaptin-5 and Rabex-5 are neoplastic tumour suppressor genes that interact to modulate Rab5 dynamics in Drosophila melanogaster☆

  2014influential citation
• Sizing it up: the mechanical feedback hypothesis of organ growth regulation.

  2014cites this paper