Genetic Variation

Á. Láruson,F. A. Reed

Published 2020 in Population Genetics with R

ABSTRACT

An introduction to randomness and the neutral theory of molecular evolution and how it contributes to levels of genetic diversity in populations. The estimation of random shifts in allele frequencies over time is discussed using the binomial probability distribution. This chapter visualizes how different initial allele frequencies relate to their probability of being fixed in a population when only drift is acting. The outputs of multiple simulations of a population undergoing random increase and decrease in allele frequencies per generation are built, run, and visualized. The fixation index (F) is introduced to quantify the loss of genetic variance over time.

PUBLICATION RECORD

  • Publication year

    2020

  • Venue

    Population Genetics with R

  • Publication date

    2020-02-02

  • Fields of study

    Not labeled

  • Identifiers
  • External record

    Open on Semantic Scholar

  • Source metadata

    Semantic Scholar

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