Elucidation of the potential disease-promoting influence of IgM apoptotic cell-reactive antibodies in lupus

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Lupus

• Publication date

  2016-06-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1177/0961203315624023PMID 26743320
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  1994cited by this paper
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  1990cited by this paper
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• [Erythematosus].

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