Contributions of Pain Sensitivity and Colonic Motility to IBS Symptom Severity and Predominant Bowel Habits

No abstract is available for this paper.

• Publication year

  2008

• Venue

  American Journal of Gastroenterology

• Publication date

  2008-10-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1111/j.1572-0241.2008.02066.xPMID 18684175PMCID PMC3855425
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Increased colonic pain sensitivity in irritable bowel syndrome is the result of an increased tendency to report pain rather than increased neurosensory sensitivity

  2008cited by this paper
• Lipid-induced colonic hypersensitivity in the irritable bowel syndrome: the role of bowel habit, sex, and psychologic factors.

  2007cited by this paper
• FUNCTIONAL BOWEL DISORDERS

  2007cited by this paper
• ROME III: The Functional Gastrointestinal Disorders

  2007cited by this paper
• Rectal afferent hypersensitivity and compliance in irritable bowel syndrome: differences between diarrhoea-predominant and constipation-predominant subgroups

  2006cited by this paper
• Meal induced rectosigmoid tone modification: a low caloric meal accurately separates functional and organic gastrointestinal disease patients

  2006cited by this paper
• Rome III: The Functional Gastrointestinal Disorders

  2006cited by this paper
• Normal aspects of colorectal motility and abnormalities in slow transit constipation.

  2005cited by this paper
• Visceral Sensitivity and Symptoms in Patients with Constipation- or Diarrhea-predominant Irritable Bowel Syndrome (IBS): Effect of a Low-Fat Intraduodenal Infusion

  2005cited by this paper
• EUS Guided Fine Needle Aspiration of Suspected Hilar Cholangiocarcinoma in Potentially Operable Patients with Negative Brush Cytology

  2004cited by this paper
• Twenty-four-hour manometric study of colonic propulsive activity in patients with diarrhea due to inflammatory (ulcerative colitis) and non-inflammatory (irritable bowel syndrome) conditions

  2004cited by this paper
• The usual medical care for irritable bowel syndrome

  2004cited by this paper
• Abnormal Colonic Propagated Activity in Patients with Slow Transit Constipation and Constipation-Predominant Irritable Bowel Syndrome

  2004cited by this paper
• Pain from Rectal Distension in Women with Irritable Bowel Syndrome (Relationship to Sexual Abuse)

  2004cited by this paper
• Irritable bowel syndrome subtypes according to bowel habit: revisiting the alternating subtype

  2003cited by this paper
• Exaggerated motility of the descending colon with repetitive distention of the sigmoid colon in patients with irritable bowel syndrome

  2002cited by this paper
• Rectal distention testing in patients with irritable bowel syndrome: sensitivity, specificity, and predictive values of pain sensory thresholds.

  2002cited by this paper
• AGA technical review on irritable bowel syndrome.

  2002cited by this paper
• Compliance, tone and sensitivity of the rectum in different subtypes of irritable bowel syndrome

  2002cited by this paper
• An exaggerated sensory component of the gastrocolonic response in patients with irritable bowel syndrome

  2001cited by this paper
• What determines severity among patients with painful functional bowel disorders?

  2000cited by this paper
• Abnormal Propagation Pattern of Duodenal Pressure Waves in the Irritable Bowel Syndrome (IBS)

  2000cited by this paper
• Functional bowel disorders and functional abdominal pain

  1999cited by this paper
• Standardization of Barostat Procedures for Testing Smooth Muscle Tone and Sensory Thresholds in the Gastrointestinal Tract

  1997influential reference
• The irritable bowel severity scoring system: a simple method of monitoring irritable bowel syndrome and its progress

  1997influential reference
• Stool form scale as a useful guide to intestinal transit time.

  1997cited by this paper
• Altered rectal perception is a biological marker of patients with irritable bowel syndrome.

  1995cited by this paper
• Colonic tone and motility in patients with irritable bowel syndrome.

  1992cited by this paper
• Anorectal manometry in irritable bowel syndrome: differences between diarrhoea and constipation predominant subjects.

  1990cited by this paper
• Tolerance for rectosigmoid distention in irritable bowel syndrome.

  1990influential reference
• Increased segmental activity and intraluminal pressures in the sigmoid colon of patients with the irritable bowel syndrome.

  1989cited by this paper
• Colonic motility, autonomic function, and gastrointestinal hormones under psychological stress on irritable bowel syndrome.

  1987cited by this paper
• The Effect of Stress on Colon Motor and Electrical Activity in Irritable Bowel Syndrome

  1985cited by this paper
• Irritable bowel syndrome

  1981cited by this paper
• Irritable bowel syndrome: physiological and psychological differences between diarrhea-predominant and constipation-predominant patients.

  1980influential reference
• Colonic myoelectrical activity in irritable-bowel syndrome. Effect of eating and anticholinergics.

  1978cited by this paper
• Pain from distension of the pelvic colon by inflating a balloon in the irritable colon syndrome 1

  1973cited by this paper
• Comparison of the effect of meals and prostigmine on the proximal and distal colon in patients with and without diarrhoea.

  1966cited by this paper

• Characterisation of MRGPRX2+ mast cells in irritable bowel syndrome

  2025cites this paper
• Randomized trial: Peppermint oil (menthol) pharmacokinetics in children and effects on gut motility in children with functional abdominal pain: 540 mg vs. 900 mg dose comparison

  2025cites this paper
• Patterns of prescription and discontinuation of glucagon-like peptide-1 receptor agonists among patients with irritable bowel syndrome

  2025cites this paper
• Increased Allergic Rhinitis Prevalence and Symptom Severity in Patients With Irritable Bowel Syndrome

  2025cites this paper
• The long road to diagnosis, from gastroesophageal reflux disease, through Barrett's esophagus, to visceral hypersensitivity: a case report

  2025cites this paper
• Animal models with characteristics of irritable bowel syndrome with diarrhea: current applications and future perspectives.

  2024cites this paper
• Intracerebroventricular Administration of TRH Agonist, RX-77368 Alleviates Visceral Pain Induced by Colorectal Distension in Rats.

  2024cites this paper
• Effects of a Protease Inhibitor Camostat Mesilate on Gut Microbial Function in Patients with Irritable Bowel Syndrome: A Pilot Randomized Placebo-Controlled Study

  2024cites this paper
• Diet–microbial cross–talk underlying increased visceral perception

  2023cites this paper
• A Tritordeum-Based Diet for Female Patients with Diarrhea-Predominant Irritable Bowel Syndrome: Effects on Abdominal Bloating and Psychological Symptoms

  2023cites this paper
• Irritable Bowel Syndrome and the Gut Microbiome: A Comprehensive Review

  2023cites this paper
• Factors influencing rectal hypersensitivity in irritable bowel syndrome: A systematic review and meta‐analysis

  2022cites this paper
• Involvement of toll-like receptor 5 in mouse model of colonic hypersensitivity induced by neonatal maternal separation

  2022cites this paper
• Voiding and storage symptoms in depression/anxiety.

  2021cites this paper
• Oral and parenteral anti‐neuropathic agents for the management of pain and discomfort in irritable bowel syndrome: A systematic review and meta‐analysis

  2021cites this paper
• Dynamics of clinical manifestations of irritable bowel syndrome against the background of cytoprotector rebamipide intake: intermediate results of the SOKRAT program

  2021cites this paper
• Development of colonic transit time and ultrasound imaging tools as objective indicators for assessing abnormal defecation associated with food intake: a narrative review based on previous scientific knowledge

  2021cites this paper
• The influence of gut microbiome on progression of overactive bladder symptoms: a community-based 3-year longitudinal study in Aomori, Japan

  2021cites this paper
• Improvement in constipation and diarrhea is associated with improved abdominal pain in patients with functional bowel disorders

  2021cites this paper
• Therapeutic Effects of Berberine Hydrochloride on Stress-Induced Diarrhea-Predominant Irritable Bowel Syndrome Rats by Inhibiting Neurotransmission in Colonic Smooth Muscle

  2021cites this paper
• The interplay between pancreatic enzymes insufficiency and irritable bowel syndrome.

  2021cites this paper
• Central regulatory mechanisms of visceral sensation in response to colonic distension with special reference to brain orexin.

  2021cites this paper
• Evidence-based clinical practice guidelines for irritable bowel syndrome 2020

  2021cites this paper
• Update S3-Leitlinie Reizdarmsyndrom: Definition, Pathophysiologie, Diagnostik und Therapie. Gemeinsame Leitlinie der Deutschen Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS) und der Deutschen Gesellschaft für Neurogastroenterologie und Motilität (DGNM) – Juni 2021

  2021cites this paper
• If It All Comes Down to Bodily Awareness, How Do We Know? Assessing Bodily Awareness

  2020cites this paper
• Intestinal Barrier, Permeability and Nonspecific Inflammation in Functional Gastrointestinal Disorders

  2020cites this paper
• Increasing Rates of Opioid Prescriptions for Gastrointestinal Diseases in the United States.

  2020cites this paper
• Refractory Gastro-oesophageal Reflux Disease and Laryngopharyngeal Reflux - Use the Bottom up Approach

  2020cites this paper
• Does Depression Contribute to the Bladder and Bowel Complaint in Parkinson's Disease Patients?

  2020cites this paper
• Comorbid irritable bowel syndrome symptoms and headache have greater association with anxiety than depression

  2020cites this paper
• Pathogenesis of irritable bowel syndrome

  2020cites this paper
• Кишечный барьер, кишечная проницаемость, неспецифическое воспаление и их роль в формировании функциональных заболеваний желудочно-кишечного тракта

  2020cites this paper
• Visceral hypersensitivity is together with psychological distress and female gender associated with severity of IBS‐like symptoms in quiescent ulcerative colitis

  2020cites this paper
• Effect of resolvins on sensitisation of TRPV1 and visceral hypersensitivity in IBS

  2020cites this paper
• Quality of Life of Patients with Irritable Bowel Syndrome

  2020cites this paper
• Depression and Structural Factors Are Associated With Symptoms in Patients of Irritable Bowel Syndrome With Diarrhea

  2020cites this paper
• Associations among neurophysiology measures in irritable bowel syndrome (IBS) and their relevance for IBS symptoms

  2020cites this paper
• Multi-target Treatment for Irritable Bowel Syndrome with STW 5: Pharmacological Modes of Action.

  2020cites this paper
• Altered gut microbiome associated with overactive bladder and daily urinary urgency

  2020cites this paper
• The Effect of Phloroglucinol in Patients With Diarrhea-predominant Irritable Bowel Syndrome: A Randomized, Double-blind, Placebo-controlled Trial

  2020influential citation
• Stigma and irritable bowel syndrome: a taboo subject?

  2020cites this paper
• The Microbiome and Irritable Bowel Syndrome – A Review on the Pathophysiology, Current Research and Future Therapy

  2019cites this paper
• Treatment of visceral pain associated with irritable bowel syndrome using acupuncture: Mechanism of action

  2019cites this paper
• Increased expression of brain-derived neurotrophic factor is correlated with visceral hypersensitivity in patients with diarrhea-predominant irritable bowel syndrome

  2019cites this paper
• Rol de los antiespasmódicos en el manejo del síndrome de intestino irritable

  2019cites this paper
• Observational cohort study: Getting to the bottom of laryngopharyngeal reflux—It’s a motility disorder and not just about the acid

  2019cites this paper
• EphrinB2/ephB2‐mediated myenteric synaptic plasticity: mechanisms underlying the persistent muscle hypercontractility and pain in postinfectious IBS

  2019cites this paper
• Cumulative Effects of Psychologic Distress, Visceral Hypersensitivity, and Abnormal Transit on Patient-reported Outcomes in Irritable Bowel Syndrome.

  2019cites this paper
• The role of antispasmodics in managing irritable bowel syndrome

  2019cites this paper
• Increased Postprandial Colonic Motility and Autonomic Nervous System Activity in Patients With Irritable Bowel Syndrome: A Prospective Study

  2018cites this paper
• Mechanisms of Stress-induced Visceral Pain

  2018cites this paper
• Inhibitory effects of patchouli alcohol on stress-induced diarrhea-predominant irritable bowel syndrome

  2018cites this paper
• Systemic cytokines are elevated in a subset of patients with irritable bowel syndrome but largely unrelated to symptom characteristics

  2018cites this paper
• Stratification and model-based analysis of patients with Irritable Bowel Syndrome using advanced biostatistics and medical data mining techniques

  2018cites this paper
• Effects of Fengliao-Changweikang in Diarrhea-predominant Irritable Bowel Syndrome Rats and Its Mechanism Involving Colonic Motility

  2018cites this paper
• Cognitive behavioral therapy for irritable bowel syndrome

  2017cites this paper
• Fecal incontinence in irritable bowel syndrome (IBS): Prevalence and associated factors in Swedish and American patients

  2017cites this paper
• Colonic N‐methyl‐d‐aspartate receptor contributes to visceral hypersensitivity in irritable bowel syndrome

  2017cites this paper
• Randomized, placebo-controlled, phase IV pilot study of ramosetron to evaluate the co-primary end points in male patients with irritable bowel syndrome with diarrhea

  2017cites this paper
• Evaluation of the irritable bowel syndrome severity index in Japanese male patients with irritable bowel syndrome with diarrhea

  2017cites this paper
• Fecal incontinence in irritable bowel syndrome: Prevalence and associated factors in Swedish and American patients

  2017cites this paper
• Immunological and Microbiological perspectives on Irritable Bowel Syndrome.

  2017cites this paper
• Plausibility criteria for putative pathophysiological mechanisms in functional gastrointestinal disorders: a consensus of experts

  2017cites this paper
• Visceral hypersensitivity is associated with GI symptom severity in functional GI disorders: consistent findings from five different patient cohorts

  2016cites this paper
• Biopsychosocial Aspects of Functional Gastrointestinal Disorders.

  2016cites this paper
• The Role of Visceral Hypersensitivity in Irritable Bowel Syndrome: Pharmacological Targets and Novel Treatments

  2016cites this paper
• Overlapping Chronic Pain Conditions: Implications for Diagnosis and Classification.

  2016cites this paper
• Corticotropin-Releasing Hormone Receptor 2 Gene Variants in Irritable Bowel Syndrome

  2016cites this paper
• Ramosetron Reduces Symptoms of Irritable Bowel Syndrome With Diarrhea and Improves Quality of Life in Women.

  2016cites this paper
• Abdominal bloating is the most bothersome symptom in irritable bowel syndrome with constipation (IBS-C): a large population-based Internet survey in Japan

  2016cites this paper
• Biomarkers to distinguish functional constipation from irritable bowel syndrome with constipation

  2016cites this paper
• Recent advances in the diagnosis of irritable bowel syndrome

  2015cites this paper
• Systematic review: instruments to assess abdominal pain in irritable bowel syndrome

  2015cites this paper
• Altered vasoactive intestinal peptides expression in irritable bowel syndrome patients and rats with trinitrobenzene sulfonic acid-induced colitis.

  2015cites this paper
• No association between the common calcium-sensing receptor polymorphism rs1801725 and irritable bowel syndrome

  2015influential citation
• Irritable bowel syndrome: A comparison of subtypes

  2015cites this paper
• Antispasmodic Effects of Myrrh due to Calcium Antagonistic Effects in Inflamed Rat Small Intestinal Preparations

  2015cites this paper
• Antinociceptive action against colonic distension by brain orexin in conscious rats.

  2015influential citation
• Evidence-based clinical practice guidelines for irritable bowel syndrome

  2014cites this paper
• Effect of ramosetron on stool consistency in male patients with irritable bowel syndrome with diarrhea.

  2014cites this paper
• The severity of irritable bowel syndrome or the presence of fibromyalgia influencing the perception of visceral and somatic stimuli

  2014cites this paper
• Mild Moxibustion Decreases the Expression of Prokineticin 2 and Prokineticin Receptor 2 in the Colon and Spinal Cord of Rats with Irritable Bowel Syndrome

  2014cites this paper
• Motility response to colonic distention is increased in postinfectious irritable bowel syndrome (PI‐IBS)

  2014influential citation
• Treatment of abdominal pain in irritable bowel syndrome

  2014cites this paper
• Is irritable bowel syndrome an organic disorder?

  2014cites this paper
• Development and validation of diagnostic tools for adolescent chronic pain patients

  2014cites this paper
• Effect of transcranial magnetic stimulation on rectal sensitivity in irritable bowel syndrome: a randomized, placebo‐controlled pilot study

  2014cites this paper
• Role of antispasmodics in the treatment of irritable bowel syndrome.

  2014cites this paper
• When and How Should We Study Colonic Motility

  2014cites this paper
• Novel Insights Into The Mechanisms Of Post-Infectious Irritable Bowel Syndrome Using Experimental Giardiasis

  2014cites this paper
• The colorectal response to butyrate in health and IBS

  2014cites this paper
• Stress and visceral pain: Focusing on irritable bowel syndrome

  2013cites this paper
• Management des Reizdarmsyndroms

  2013cites this paper
• Interaction between preprandial and postprandial rectal sensory and motor abnormalities in IBS

  2013cites this paper
• Which psychological factors exacerbate irritable bowel syndrome? Development of a comprehensive model.

  2013cites this paper
• Fecal Protease Activity Is Associated with Compositional Alterations in the Intestinal Microbiota

  2013cites this paper
• Increased pain sensitivity among adults reporting irritable bowel syndrome symptoms in a large population‐based study

  2013cites this paper
• Expression of the nociceptin/orphanin FQ receptor in the intestinal mucosa of IBS patients

  2013cites this paper
• Acupuncture transcutaneous electrical nerve stimulation reduces discomfort associated with barostat-induced rectal distension: a randomized-controlled study.

  2013cites this paper
• Rome III functional constipation and irritable bowel syndrome with constipation are similar disorders within a spectrum of sensitization, regulated by serotonin.

  2013cites this paper