Thymosin beta4 accelerates wound healing.

No abstract is available for this paper.

• Publication year

  1999

• Venue

  Journal of Investigative Dermatology

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 10469335
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Vascular endothelial growth factor mediates angiogenic activity during the proliferative phase of wound healing.

  1998cited by this paper
• Thymosin alpha 1 stimulates endothelial cell migration, angiogenesis, and wound healing.

  1998cited by this paper
• Thymosin β4 stimulates directional migration of human umbilical vein endothelial cells

  1997cited by this paper
• Enhanced biosynthesis of extracellular matrix proteins and TGF‐β1 by polyinosinic‐polycytidylic acid during cutaneous wound healing in vivo

  1996cited by this paper
• Biochemical and antibacterial analysis of human wound and blister fluid.

  1996cited by this paper
• Increasing intracellular concentrations of thymosin beta 4 in PtK2 cells: effects on stress fibers, cytokinesis, and cell spreading.

  1995cited by this paper
• Isolation and utilization of epidermal keratinocytes for oncogene research.

  1995cited by this paper
• Matrigel induces thymosin beta 4 gene in differentiating endothelial cells.

  1995cited by this paper
• Distribution and biological activity ofβ-thymosins

  1994cited by this paper
• Beta thymosins as actin binding peptides

  1994cited by this paper
• Effects of thymosin beta 4 and thymosin beta 10 on actin structures in living cells.

  1994cited by this paper
• How profilin promotes actin filament assembly in the presence of thymosin beta 4.

  1993cited by this paper
• Thymosin beta 10 and thymosin beta 4 are both actin monomer sequestering proteins.

  1993cited by this paper
• Enhanced wound healing in animal models by interferon and an interferon inducer

  1992cited by this paper
• Thymosin beta 4 (Fx peptide) is a potent regulator of actin polymerization in living cells.

  1992cited by this paper
• Interaction of thymosin beta 4 with muscle and platelet actin: implications for actin sequestration in resting platelets.

  1992cited by this paper
• Thymosin beta 4 sequesters the majority of G-actin in resting human polymorphonuclear leukocytes

  1992cited by this paper
• Differential expression of thymosin genes in human tumors and in the developing human kidney

  1991cited by this paper
• Monospecific antibodies implicate basic fibroblast growth factor in normal wound repair.

  1989cited by this paper
• Enzyme immunoassay measurement of thymosin beta 4 in human serum.

  1988cited by this paper
• Angiogenic activity in human wound fluid.

  1987cited by this paper
• Differential expression of the human thymosin-beta 4 gene in lymphocytes, macrophages, and granulocytes.

  1987cited by this paper
• Immunochemical studies on thymosin: radioimmunoassay of thymosin beta 4.

  1984cited by this paper
• Chemical characterization of thymosin beta 4.

  1982cited by this paper
• Complete amino acid sequence of bovine thymosin beta 4: a thymic hormone that induces terminal deoxynucleotidyl transferase activity in thymocyte populations.

  1981cited by this paper
• Modulation of terminal deoxynucleotidyl transferase activity by thymosin

  1981cited by this paper

• Suckerin Colloids and Hydrogels With Low Immunogenicity as Resorbable and Hemostatic Tissue Adhesives for Wound Healing.

  2026cites this paper
• Alkaline Phosphatase-Triggered Spatiotemporal Repair of Corneal Injury with TB500 Peptide Hydrogel.

  2025cites this paper
• Growth factors IGF-1 and KGF and adipose-derived stem cells promote migration and viability of primary human keratinocytes in an in vitro wound model

  2025cites this paper
• Review of Thymic Peptides and Hormones: From Their Properties to Clinical Application

  2024cites this paper
• Designing Composite Stimuli-Responsive Hydrogels for Wound Healing Applications: The State-of-the-Art and Recent Discoveries

  2024cites this paper
• Histological Evaluation of Effect of Thymosin Beta 4 on Wound Healing of Skin

  2024cites this paper
• Effect of thymosin β4 on lipopolysaccharide‑stimulated brain microvascular endothelial cell remodeling: A possible role in blood‑brain barrier injury

  2023cites this paper
• Targeted Deletion of Thymosin Beta 4 in Hepatic Stellate Cells Ameliorates Liver Fibrosis in a Transgenic Mouse Model

  2023cites this paper
• Thymosin beta 4: A potential novel adjunct treatment for bacterial keratitis.

  2023cites this paper
• Thymosin beta-4 participate in antibacterial immunity and wound healing in black tiger shrimp,Penaeus monodon.

  2023cites this paper
• Role of Actin-Binding Proteins in Skeletal Myogenesis

  2023cites this paper
• Thymosin beta-4 – A potential tool in healing middle ear lesions in adult mammals

  2023cites this paper
• Thymus transplantation regulates blood pressure and alleviates hypertension-associated heart and kidney damage via transcription factors FoxN1 pathway.

  2023cites this paper
• Cell starvation increases uptake of extracellular Thymosin β4 and its complexes with calcium.

  2023cites this paper
• An approach for identifying in silico peptides against authentic metabolites: in vitro characterization of thymosin β4 metabolites

  2022cites this paper
• The Involvement of Alarmins in the Pathogenesis of Sjögren’s Syndrome

  2022cites this paper
• Effects of thymosin β4-derived peptides on migration and invasion of ovarian cancer cells

  2021cites this paper
• In-silico Screening of Phytoconstituents on Wound Healing Targets-Approaches and Current Status.

  2021cites this paper
• Association between Thymosin beta-4, acute kidney injury, and mortality in patients with sepsis: An observational cohort study.

  2021cites this paper
• Discovery of Thymosin Beta-4 as a Human Exerkine and Growth Factor.

  2021cites this paper
• The Role of Endogenous Antimicrobial Peptides in Modulating Innate Immunity of the Ocular Surface in Dry Eye Diseases

  2021cites this paper
• Multiple potential roles of thymosin β4 in the growth and development of hair follicles

  2021cites this paper
• Recombinant human thymosin beta‐4 (rhTβ4) improved scalp condition and microbiome homeostasis in seborrheic dermatitis

  2021cites this paper
• β-thymosin is an essential regulator of stem cell proliferation and neuron regeneration in planarian (Dugesia japonica).

  2021cites this paper
• Leading edge: emerging drug, cell, and gene therapies for junctional epidermolysis bullosa

  2020cites this paper
• Thymosinβ4 alleviates cholestatic liver fibrosis in mice through downregulating PDGF/PDGFR and TGFβ/Smad pathways.

  2020cites this paper
• Alcoholic and Non-Alcoholic Liver Diseases: Promising Molecular Drug Targets and their Clinical Development.

  2020cites this paper
• Thymosin β4 cytoplasmic/nuclear translocation as a new marker of cellular stress. A Caco2 case study

  2020cites this paper
• Peptides from Animal Origin: A Systematic Review on Biological Sources and Effects on Skin Wounds

  2020cites this paper
• Differences in proteomic profile between two haemocyte types, granulocytes and hyalinocytes, of the flat oyster Ostrea edulis.

  2020cites this paper
• Thymosin β4 dynamics during chicken enteroid development

  2020cites this paper
• The Protective Effects of Thymosin-β-4 in a Rat Model of Ischemic Acute Kidney Injury

  2019cites this paper
• Cloning, Expression and Effects of P. americana Thymosin on Wound Healing

  2019cites this paper
• Light‐Activated Tissue‐Integrating Sutures as Surgical Nanodevices

  2019cites this paper
• Metallacarboranes as a tool for enhancing the activity of therapeutic peptides

  2019cites this paper
• Thymosin β4: potential to treat epidermolysis bullosa and other severe dermal injuries

  2019cites this paper
• Expression and localisation of thymosin beta-4 in the developing human early fetal heart

  2018cites this paper
• Plasminogen/thrombomodulin signaling enhances VEGF expression to promote cutaneous wound healing

  2018cites this paper
• Widening control of fin inter‐rays in zebrafish and inferences about actinopterygian fins

  2018cites this paper
• Thymosin β4 promotes glucose-impaired endothelial progenitor cell function via Akt/endothelial nitric oxide synthesis signaling pathway

  2018cites this paper
• Mechanisms in hypertension and target organ damage: Is the role of the thymus key? (Review)

  2018cites this paper
• Thymosin beta 4-Induced Autophagy Increases Cholinergic Signaling in PrP (106–126)-Treated HT22 Cells

  2018cites this paper
• Wound healing in the eye: Therapeutic prospects

  2018cites this paper
• RGN-259 (thymosin β4) improves clinically important dry eye efficacies in comparison with prescription drugs in a dry eye model

  2018cites this paper
• Thymosin beta 4 and the eye: the journey from bench to bedside

  2018cites this paper
• An Investigation on the Therapeutic Effect of Thymosin β4 and Its Expression Levels in Streptozotocin-Induced Diabetic Mice

  2018cites this paper
• Thymosin β4 has a major role in dermal burn wound healing that involves actin cytoskeletal remodelling via heat‐shock protein 70

  2017cites this paper
• Thymosin beta-4 overexpression correlates with high-risk groups in gastric gastrointestinal stromal tumors: A retrospective analysis by immunohistochemistry.

  2017cites this paper
• Comparative proteomics of paired vocal fold and oral mucosa fibroblasts

  2017cites this paper
• Thymosin β4 in rheumatoid arthritis: Friend or foe.

  2017cites this paper
• Thymosin beta-4 regulates activation of hepatic stellate cells via hedgehog signaling

  2017cites this paper
• Safety and efficacy of autologous thymosin β4 pre-treated endothelial progenitor cell transplantation in patients with acute ST segment elevation myocardial infarction: A pilot study.

  2016cites this paper
• Endogenous Mechanisms of Cardiac Regeneration.

  2016cites this paper
• Inhibition of Angiogenesis Associated with Ovarian Cancer By Nanoparticles of Cerium Oxide (CIP)

  2016cites this paper
• A Tobacco-Derived Thymosin β4 Concatemer Promotes Cell Proliferation and Wound Healing in Mice

  2016cites this paper
• Thymosin Beta 4 Is a Potential Regulator of Hepatic Stellate Cells.

  2016cites this paper
• The Hidden Function of Vitamin D

  2016cites this paper
• Thymosin β4 Promotes Dermal Healing.

  2016cites this paper
• Thymosin β as an Actin-binding Protein with a Variety of Functions.

  2016cites this paper
• Pivotal Cytoprotective Mediators and Promising Therapeutic Strategies for Endothelial Progenitor Cell-Based Cardiovascular Regeneration

  2016cites this paper
• Actin-Induced Structure in the Beta-Thymosin Family of Intrinsically Disordered Proteins.

  2016cites this paper
• Thymosin β4 overexpression regulates neuron production and spatial distribution in the developing avian optic tectum

  2016cites this paper
• Thymosin beta 4 ophthalmic solution for dry eye: a randomized, placebo-controlled, Phase II clinical trial conducted using the controlled adverse environment (CAE™) model

  2015cites this paper
• Actin cytoskeletal rearrangement and dysfunction due to activation of the receptor for advanced glycation end products is inhibited by thymosin beta 4

  2015cites this paper
• Thymosin &bgr;4 Significantly Improves Signs and Symptoms of Severe Dry Eye in a Phase 2 Randomized Trial

  2015cites this paper
• Hepatic Stellate Cells Express Thymosin Beta 4 in Chronically Damaged Liver

  2015cites this paper
• First insights into the giant panda (Ailuropoda melanoleuca) blood transcriptome: a resource for novel gene loci and immunogenetics

  2015cites this paper
• Synthesis and biological screening of small molecule peptides based on the amino acid sequence of thymosin β4

  2015cites this paper
• Potential Role of Thymosin Beta 4 in Liver Fibrosis

  2015cites this paper
• Effect of thymosin beta 4 in the presence of up-regulation of the insulin-like growth factor-1 signaling pathway on high-glucose-exposed vascular endothelial cells.

  2015cites this paper
• Thymosin Beta-4 Recombinant Adeno-associated Virus Enhances Human Nucleus Pulposus Cell Proliferation and Reduces Cell Apoptosis and Senescence

  2015cites this paper
• Advances in the basic and clinical applications of thymosin β4

  2015cites this paper
• Targeting the Phosphatidylinositide-3 Kinase Pathway and the Mitogen-Activated-Protein Kinase Pathway through Thymosin-beta4, Exercise, and Negative Regulators to Promote Retinal Ganglion Cell Survival or Regeneration

  2015cites this paper
• Thymosin β4 attenuates microcirculatory and hemodynamic destabilization in sepsis

  2015cites this paper
• Thymosin beta 4 is associated with RUNX2 expression through the Smad and Akt signaling pathways in mouse dental epithelial cells

  2015cites this paper
• Increases in plasma Tβ4 after intracardiac cell therapy in chronic ischemic heart failure is associated with symptomatic improvement.

  2015cites this paper
• MALDI-imaging reveals thymosin beta-4 as an independent prognostic marker for colorectal cancer

  2015cites this paper
• Thymosin beta 4 improves dermal burn wound healing via downregulation of receptor of advanced glycation end products in db/db mice.

  2014cites this paper
• Multicenter matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI MSI) identifies proteomic differences in breast-cancer-associated stroma.

  2014cites this paper
• Thymosin β4 administration enhances fracture healing in mice

  2014cites this paper
• Depletion of Thymosin β4 Promotes the Proliferation, Migration, and Activation of Human Hepatic Stellate Cells

  2014cites this paper
• In vivo growth suppression of CT-26 mouse colorectal cancer cells by adenovirus-expressed small hairpin RNA specifically targeting thymosin beta-4 mRNA

  2014cites this paper
• A dose-response study of thymosin β4 for the treatment of acute stroke.

  2014cites this paper
• Thymosin β4 induces invasion and migration of human colorectal cancer cells through the ILK/AKT/β-catenin signaling pathway.

  2014cites this paper
• Thymosin β4 Improves Neurological Outcome and Enhances Induced Oligodendrogenesis in the Rat after ICH

  2014cites this paper
• Thymosin Beta4 Regulates Cardiac Valve Formation Via Endothelial-Mesenchymal Transformation in Zebrafish Embryos

  2014cites this paper
• Thymosin-β4 prevents cardiac rupture and improves cardiac function in mice with myocardial infarction.

  2014cites this paper
• Identification of black market products and potential doping agents in Germany 2010–2013

  2014cites this paper
• Roles and Mechanisms of β-Thymosins in Cell Migration and Cancer Metastasis: An Update

  2013cites this paper
• Cross‐talk between intraepithelial γδ T cells and epithelial cells

  2013cites this paper
• Quantitative analysis of thymosin β4 in whole saliva by capillary electrophoresis–mass spectrometry using multiple ions monitoring (CE‐MIM‐MS)

  2013cites this paper
• Effects of thymosin β4 on the bone formation of calvarial defects in rats.

  2013cites this paper
• Nanoceria: A Rare-Earth Nanoparticle as a Novel Anti-Angiogenic Therapeutic Agent in Ovarian Cancer

  2013cites this paper
• The Escherichia coli-Derived Thymosin β4 Concatemer Promotes Cell Proliferation and Healing Wound in Mice

  2013cites this paper
• Angiogenic Induction by Trichinella spiralis Infection through Thymosin β4

  2013cites this paper
• Thymosin beta-4 promotes mesenchymal stem cell proliferation via an interleukin-8-dependent mechanism.

  2013cites this paper
• Thymosin β4 and its degradation product, Ac-SDKP, are novel reparative factors in renal fibrosis

  2013cites this paper
• Cellular Trafficking of Thymosin Beta-4 in HEPG2 Cells Following Serum Starvation

  2013cites this paper
• Nanog suppresses cell migration by downregulating thymosin β4 and Rnd3.

  2013cites this paper
• Expression Patterns of Thymosin β4 and Cancer Stem Cell Marker CD133 in Ovarian Cancers

  2013cites this paper