How Reliable Is a Negative Blood Culture Result? Volume of Blood Submitted for Culture in Routine Practice in a Children's Hospital

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Pediatrics

• Publication date

  2007-05-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1542/peds.2006-0440PMID 17473088
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• A comparison of two blood culture procedures for the isolation of staphylococci in a paediatric intensive care unit.

  2005cited by this paper
• Bacteremia among children admitted to a rural hospital in Kenya.

  2005cited by this paper
• Blood cultures in newborns and children: optimising an everyday test

  2002cited by this paper
• Frequency of Low-Level Bacteremia in Children from Birth to Fifteen Years of Age

  2000cited by this paper
• Impact of infectious diseases specialists and microbiological data on the appropriateness of antimicrobial therapy for bacteremia.

  1999cited by this paper
• A blood micro-culture system for the diagnosis of bacteremia in pediatric patients.

  1998cited by this paper
• Frequency of low level bacteremia in infants from birth to two months of age.

  1997cited by this paper
• VOLUME OF BLOOD REQUIRED TO DETECT COMMON NEONATAL PATHOGENS †1442

  1996cited by this paper
• Volume of blood required to detect common neonatal pathogens.

  1996cited by this paper
• Effect of number of blood cultures and volume of blood on detection of bacteremia in children.

  1996cited by this paper
• Yield of positive blood cultures in pediatric oncology patients by a new method of blood culture collection.

  1996cited by this paper
• Bacterial concentration and blood volume required for a positive blood culture.

  1995cited by this paper
• Application of new sepsis definitions to evaluate outcome of pediatric patients with severe systemic infections.

  1995cited by this paper
• Effects of volume and periodicity on blood cultures

  1994cited by this paper
• Detection of Bacteremia in Adults: Consequences of Culturing an Inadequate Volume of Blood

  1993cited by this paper
• Theoretical aspects of detection of bacteraemia as a function of the volume of blood cultured

  1993cited by this paper
• Effect of sample volume on yield of positive blood cultures from adult patients with haematological malignancy.

  1990cited by this paper
• Septic shock in children: bacterial etiologies and temporal relationships

  1990cited by this paper
• BacT/Alert: an automated colorimetric microbial detection system

  1990cited by this paper
• Importance of blood volume cultured in the detection of bacteremia

  1989cited by this paper
• Blood cultures.

  1987cited by this paper
• Diagnostic Decision: Blood Cultures

  1987cited by this paper
• Volume of blood submitted for culture from neonates

  1986cited by this paper
• Blood cultures: issues and controversies.

  1986cited by this paper
• Specimen volume versus yield in the BACTEC blood culture system

  1985cited by this paper
• Relationship between the magnitude of bacteremia in children and the clinical disease.

  1982cited by this paper
• Comparison of recovery of organisms from blood cultures diluted 10% (volume/volume) and 20% (volume/volume)

  1982cited by this paper
• Controlled evaluation of the volume of blood cultured in detection of bacteremia and fungemia

  1982cited by this paper
• Volume of blood removed for analytical purposes during hospitalization of low-birthweight infants.

  1981cited by this paper
• Effect of blood dilution on recovery of organisms from clinical blood cultures in medium containing sodium polyanethol sulfonate

  1979cited by this paper
• Evaluation of blood culture procedures in a pediatric hospital

  1979cited by this paper
• Quantitative blood cultures in childhood bacteremia.

  1978cited by this paper
• Neonatal Escherichia coli septicemia--bacterial counts in blood.

  1974cited by this paper
• Specific Gravity of Blood and Plasma at 4 and 37 °C

  1974cited by this paper
• Specific gravity of blood and plasma at 4 and 37 degrees C.

  1974cited by this paper
• Diagnosis and treatment: risks of obtaining samples of venous blood in infants.

  1966cited by this paper
• Blood cultures.

  1949cited by this paper

• Empirical antibiotic use, resistance patterns, and their impact on clinical outcomes in a Yemeni tertiary hospital.

  2026cites this paper
• High CRP and white blood cell counts are not reliable indicators of early-onset neonatal infection in full-term infants

  2026cites this paper
• Early-onset neonatal infection and cognitive impairment: a nationwide cohort study

  2026cites this paper
• Incidence and clinical outcomes of neonatal sepsis in neonatal intensive care unit admissions: a hospital-based study

  2026cites this paper
• Soluble Urokinase Plasminogen Activator Receptor in Full–Term Neonates with Sepsis: Relation to Disease Severity and Clinical Outcome

  2025cites this paper
• What is the role of pulse oximetry screening in identifying neonatal morbidities other than critical heart diseases?

  2025cites this paper
• Simple dual filter workflow for facilitating blood culture-free and sensitive detection of pathogenic bacteria from blood

  2025cites this paper
• Factors associated with positive blood cultures in children in nine African and Asian countries: the ACORN2 surveillance network

  2025cites this paper
• The relationship between gut microbiota and neonatal sepsis is an inherent link

  2025cites this paper
• MicroRNA Profiling as a Novel Tool in the Diagnostics of Late-Onset Neonatal Sepsis: A Scoping Review

  2025cites this paper
• Integrating Lean Six Sigma into Microbiology Laboratories: Insights from a Literature Review

  2025cites this paper
• Cost-effectiveness of maintaining an active hospital microbiology laboratory service in Timor-Leste

  2025cites this paper
• Evaluating the effectiveness of a two-set approach for improving blood culture positivity rates in dogs and cats.

  2025cites this paper
• Clinical, scientific and healthcare system consequences of misdiagnosing neonatal sepsis

  2025cites this paper
• Infections néonatales bactériennes et mycosiques

  2025cites this paper
• Theoretical impact of a bedside decision-making tool on antibiotic use for suspected neonatal healthcare-associated infection: an observational study

  2025cites this paper
• The Yield of One vs. Two Blood Cultures in Children: Under-Detection and Over-Testing

  2024cites this paper
• Blood cultures in paediatrics: clinical indications to obtain a blood culture

  2024cites this paper
• Shorter versus longer duration antibiotic regimens for treatment of suspected neonatal sepsis.

  2024cites this paper
• Antibiotic exposure for culture-negative early-onset sepsis in late-preterm and term newborns: an international study

  2024cites this paper
• Re-Thinking the Norms of Antibiotic Prescribing in the Neonatal Intensive Care Unit.

  2024cites this paper
• Time to positivity of Coagulase Negative Staphylococcus In Neonatal Blood Cultures as an adjunct tool to help discriminate between sepsis and contamination

  2024cites this paper
• Characterizing CRP dynamics during acute infections

  2024cites this paper
• Yield of Targeted Polymerase Chain Reaction in Probable Early-Onset Sepsis: A Prospective Cohort Study in Term and Near-Term Neonates With Negative Blood Culture Results

  2024cites this paper
• Blood cultures in paediatrics: a narrative review

  2024cites this paper
• Assessing paediatric blood culture quality: surveys of clinician and laboratory practices in Australia and New Zealand.

  2024cites this paper
• Epidemiology and Outcomes of Neonatal Sepsis: Experience from a Tertiary Australian NICU

  2024cites this paper
• Role of diagnostic tests for sepsis in children: a review

  2024cites this paper
• Early-onset neonatal sepsis: Effectiveness of classification based on ante- and intrapartum risk factors and clinical monitoring.

  2024cites this paper
• Recovery of pathogens with implementation of a weight-based algorithm for pediatric blood cultures: an observational intervention study

  2024cites this paper
• Lipopolysaccharide induced systemic inflammation and heart rate variability in a term newborn piglet model

  2024cites this paper
• Less haste, more speed: Does delayed blood culture transport time lead to adverse incubation times or yield?

  2024cites this paper
• Blood volume collected for cultures in infants with suspected neonatal sepsis

  2024cites this paper
• Neonatal bacterial sepsis.

  2024cites this paper
• Effect of in-line filtration in newborns: study protocol of the Intravenous Neonatal Central Access Safety (INCAS) randomized controlled trial

  2024cites this paper
• Shorter versus longer duration antibiotic regimens for treatment of culture-positive neonatal sepsis.

  2024cites this paper
• Umbilical cord blood culture for early onset sepsis in preterm infants

  2024influential citation
• Pediatric blood cultures—turning up the volume: a before and after intervention study

  2024influential citation
• The Diagnostic and Therapeutic Challenges of Culture Negative Sepsis

  2024cites this paper
• Time to Positive Blood Cultures Among Critically Ill Children Admitted to the PICU

  2024cites this paper
• Advancements in understanding the association of sepsis with heart rate variability in premature infants

  2024cites this paper
• Time to positivity of blood cultures in paediatric patients

  2024cites this paper
• A New Easy-to-Perform Flow Cytometry Assay for Determining Bacterial- and Viral-Infection-Induced Polymorphonuclear Neutrophil and Monocyte Membrane Marker Modulation in Febrile Patients

  2024cites this paper
• Effect of Serial Clinical Observation Complemented by Point-of-Care Blood Culture Volume Verification on Antibiotic Exposure in Newborns

  2024cites this paper
• Procalcitonin for the diagnosis of sepsis in neonates: a diagnostic test accuracy review

  2023cites this paper
• Facile Filtration-Based Workflow for Facilitating Sensitive Detection of Pathogenic Bacteria from Blood

  2023cites this paper
• Point-of-Care Verification of Blood Culture Volume in Neonates: A Feasibility Trial

  2023cites this paper
• A multi-pronged approach to improve blood culture diagnostics in different clinical departments: a single-centre experience

  2023cites this paper
• Performance of 11 Host Biomarkers Alone or in Combination in the Diagnosis of Late-Onset Sepsis in Hospitalized Neonates: The Prospective EMERAUDE Study

  2023cites this paper
• Insight Into Neonatal Sepsis: An Overview

  2023cites this paper
• Switch from intravenous-to-oral antibiotics in neonatal probable and proven early-onset infection: a prospective population-based real-life multicentre cohort study

  2023cites this paper
• Diagnostic Accuracy of Haematological Scoring System in Paired cord Blood and Peripheral Venous Blood for early Detection of Neonatal Sepsis – A Prospective Analytical Study

  2023cites this paper
• Density of antibiotic use and infectious complications in pediatric allogeneic hematopoietic cell transplantation

  2023cites this paper
• Clinical Application of a Multiplex Droplet Digital PCR in the Rapid Diagnosis of Children with Suspected Bloodstream Infections

  2023cites this paper
• Potential of Molecular Culture in Early Onset Neonatal Sepsis Diagnosis: A Proof of Principle Study

  2023cites this paper
• Distribution of Presepsin, Krebs von den Lungen 6, and Surfactant Protein A in Umbilical Cord Blood

  2022cites this paper
• Restrictive prescription of antibiotics in preterm infants with premature rupture of membranes

  2022cites this paper
• Perinatal bacterial colonization and neonatal early-onset sepsis: A case-control study

  2022cites this paper
• Abnormal Expression of SNHG7 Is a Biomarker for the Diagnosis and Prognosis of Neonatal Sepsis.

  2022cites this paper
• A positive blood culture is associated with a lower haemoglobin increment in hospitalized patients after red blood cell transfusion

  2022cites this paper
• Sources and Risk factors of a Novel MRSA Spa Type Circulating in Neonatal Intensive Care Unit

  2022cites this paper
• Efficacy and safety of switching from intravenous to oral antibiotics (amoxicillin-clavulanic acid) versus a full course of intravenous antibiotics in neonates with probable bacterial infection (RAIN): a multicentre, randomised, open-label, non-inferiority trial.

  2022cites this paper
• Systematic review of host genomic biomarkers of invasive bacterial disease: Distinguishing bacterial from non-bacterial causes of acute febrile illness

  2022cites this paper
• Serial Measurement of Interleukin-6 Enhances Chance to Exclude Early-Onset Sepsis in Very Preterm Infants

  2022cites this paper
• Practice Summary of Antimicrobial Therapy for Commonly Encountered Conditions in the Neonatal Intensive Care Unit: A Canadian Perspective

  2022cites this paper
• Excessively Prolonged Early Antibiotic Duration in Very-Low-Birth-Weight Infants: A Multicenter Prospective Cohort Study in a Developing Country

  2022cites this paper
• The Value of Perinatal Factors, Blood Biomarkers and Microbiological Colonization Screening in Predicting Neonatal Sepsis

  2022cites this paper
• A proposed framework for the clinical management of neonatal "culture-negative" sepsis.

  2022cites this paper
• The Interplay between Host Defense, Infection, and Clinical Status in Septic Patients: A Narrative Review

  2022cites this paper
• Comparative assessment of umbilical cord blood with peripheral venous blood using hematological scoring system as an early predictive screening method for the detection of early-onset neonatal sepsis in the tertiary care center of Central India

  2022cites this paper
• Short time to positivity of blood culture predicts mortality and septic shock in bacteremic patients: a systematic review and meta-analysis

  2022cites this paper
• Biomarkers and their association with bacterial illnesses in hypothermic infants.

  2022cites this paper
• Neonatal Paenibacilliosis: Paenibacillus thiaminolyticus as a Novel Cause of Neonatal Sepsis with High Risk of Sequelae in Uganda

  2022cites this paper
• Comparative microbial analysis and assessment of paired umbilical cord blood culture and peripheral venous blood culture in neonates with high risk factors to detect early onset neonatal sepsis: A study from tertiary care hospital of central India

  2022cites this paper
• Temperature threshold in the screening of bacterial infections in young infants with hypothermia

  2022cites this paper
• Cord Blood Sampling - A review of umbilical cord blood use for admission laboratory tests in the immediate newborn period.

  2022cites this paper
• [Utility of C-reactive protein in early neonatal sepsis].

  2021cites this paper
• Clinical Utility of Molecular Tests for Guiding Therapeutic Decisions in Bloodstream Staphylococcal Infections: A Meta-Analysis

  2021cites this paper
• miRNomic Signature in Very Low Birth-Weight Neonates Discriminates Late-Onset Gram-Positive Sepsis from Controls

  2021cites this paper
• Antibiotic Stewardship for the Neonatologist and Perinatologist.

  2021cites this paper
• Biomarkers for the Diagnosis of Neonatal Sepsis.

  2021cites this paper
• Neonatal sepsis at point of care.

  2021cites this paper
• Survey on antibiotic regimens for necrotizing enterocolitis prescribed by Chinese pediatricians in 2020

  2021cites this paper
• Next-generation sequencing diagnostics of bacteremia in pediatric sepsis

  2021cites this paper
• Antibiotic Stewardship in the Pediatric Dialysis Unit

  2021cites this paper
• Comparison of Microorganism Detection and Time to Positivity in Pediatric and Standard Media from Three Major Commercial Continuously Monitored Blood Culture Systems

  2021cites this paper
• Diagnostic Accuracy of Clinical Tool 'STOPS' and Serum Procalcitonin for Optimizing Antibiotic Therapy in Neonates Born at ≥ 28 Weeks of Gestation with Neonatal Sepsis

  2021cites this paper
• Neonatal Blood Culture Inoculant Volume: Feasibility and Challenges

  2021cites this paper
• How to interpret a paediatric blood culture

  2021cites this paper
• Infection Manager System (IMS) as a new hemocytometry-based bacteremia detection tool: A diagnostic accuracy study in a malaria-endemic area of Burkina Faso

  2021cites this paper
• Neonatal Escherichia coli infection in twins: clinical spectrum and management dilemma

  2021cites this paper
• Use of Rapid Molecular Polymerase Chain Reaction in Early Detection of Bacteremia in Neonates Prior to Blood Culture Positivity: A Pilot Study

  2021cites this paper
• Turkish pediatric residents' knowledge, perceptions, and practices of blood culture sampling.

  2021cites this paper
• Blood Culture Metrics Are Human Metrics: The Missed Opportunity for Clinical Laboratory Quality Measures to Improve the Overall Blood Culture Process

  2021cites this paper
• Using Classification Tree Analysis to Predict the Type of Infection in Preterm Neonates: Proof of Concept Study

  2021cites this paper
• Validity of serum and urinary hepcidin as biomarkers for late-onset sepsis in premature infants

  2021cites this paper
• Visual multiple cross displacement amplification for the rapid identification of S. agalactiae immediately from vaginal and rectal swabs

  2021cites this paper
• Eliminating Contamination in Umbilical Cord Blood Culture Sampling for Early-Onset Neonatal Sepsis

  2021cites this paper
• Clinical significance of serum miR-101-3p expression in patients with neonatal sepsis.

  2021cites this paper
• Knowledge gaps in late-onset neonatal sepsis in preterm neonates: a roadmap for future research

  2021cites this paper