Companion Protease Inhibitors for the In Situ Protection of Recombinant Proteins in Plants.

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Methods in molecular biology

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1007/978-1-4939-3289-4_8PMID 26614285
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Inhibition of protease activity by antisense RNA improves recombinant protein production in Nicotiana tabacum cv. Bright Yellow 2 (BY‐2) suspension cells

  2014cited by this paper
• A fusion protein derived from plants holds promising potential as a new oral therapy for type 2 diabetes.

  2014cited by this paper
• Recombinant plant-derived pharmaceutical proteins: current technical and economic bottlenecks

  2014cited by this paper
• Tomato cystatin SlCYS8 as a stabilizing fusion partner for human serpin expression in plants.

  2013cited by this paper
• Proteolysis of recombinant proteins in bioengineered plant cells

  2013cited by this paper
• Efficient agroinfiltration of plants for high-level transient expression of recombinant proteins.

  2013cited by this paper
• Protection of Recombinant Mammalian Antibodies from Development-Dependent Proteolysis in Leaves of Nicotiana benthamiana

  2013cited by this paper
• Agroinfiltration as an Effective and Scalable Strategy of Gene Delivery for Production of Pharmaceutical Proteins

  2013cited by this paper
• A protease activity-depleted environment for heterologous proteins migrating towards the leaf cell apoplast.

  2012cited by this paper
• Use of Transgenic Oryzacystatin-I-Expressing Plants Enhances Recombinant Protein Production

  2012cited by this paper
• Multimodal Protein Constructs for Herbivore Insect Control

  2012cited by this paper
• Recombinant plant-expressed tumour-associated MUC1 peptide is immunogenic and capable of breaking tolerance in MUC1.Tg mice.

  2011cited by this paper
• Protein body-inducing fusions for high-level production and purification of recombinant proteins in plants.

  2011cited by this paper
• Production of antibodies in plants: status after twenty years.

  2010cited by this paper
• Plant cystatins.

  2010cited by this paper
• A companion protease inhibitor for the protection of cytosol-targeted recombinant proteins in plants.

  2010cited by this paper
• Companion protease inhibitors to protect recombinant proteins in transgenic plant extracts.

  2009cited by this paper
• A SELDI‐TOF MS procedure for the detection, quantitation, and preliminary characterization of low‐molecular‐weight recombinant proteins expressed in transgenic plants

  2009cited by this paper
• Transient expression of antibodies in plants using syringe agroinfiltration.

  2009cited by this paper
• Immunological assessment of plant-derived avian flu H5/HA1 variants.

  2009cited by this paper
• Hydrophobin Fusions for High-Level Transient Protein Expression and Purification in Nicotiana benthamiana1[W][OA]

  2009cited by this paper
• Biochemical and immunological characterization of the plant-derived candidate human immunodeficiency virus type 1 mucosal vaccine CTB-MPR.

  2009cited by this paper
• pEAQ: versatile expression vectors for easy and quick transient expression of heterologous proteins in plants.

  2009cited by this paper
• Unintended molecular interactions in transgenic plants expressing clinically useful proteins: The case of bovine aprotinin traveling the potato leaf cell secretory pathway

  2009cited by this paper
• Targeting and post-translational processing of human alpha1-antichymotrypsin in BY-2 tobacco cultured cells.

  2009cited by this paper
• Transient co-expression for fast and high-yield production of antibodies with human-like N-glycans in plants.

  2009cited by this paper
• Tailoring the Specificity of a Plant Cystatin toward Herbivorous Insect Digestive Cysteine Proteases by Single Mutations at Positively Selected Amino Acid Sites1[OA]

  2008cited by this paper
• Plant proteases: from phenotypes to molecular mechanisms.

  2008cited by this paper
• Preventing unintended proteolysis in plant protein biofactories

  2008cited by this paper
• Cosecretion of Protease Inhibitor Stabilizes Antibodies Produced by Plant Roots1

  2006cited by this paper
• Immunoabsorbent nanoparticles based on a tobamovirus displaying protein A

  2006cited by this paper
• An in-built proteinase inhibitor system for the protection of recombinant proteins recovered from transgenic plants.

  2006cited by this paper
• Foreign protein degradation and instability in plants and plant tissue cultures.

  2006cited by this paper
• Protein modifications in the plant secretory pathway: current status and practical implications in molecular pharming.

  2005cited by this paper
• Production and glycosylation of plant-made pharmaceuticals: the antibodies as a challenge.

  2004cited by this paper
• A cut above the rest: the regulatory function of plant proteases

  2004cited by this paper
• An enhanced transient expression system in plants based on suppression of gene silencing by the p19 protein of tomato bushy stunt virus.

  2003cited by this paper
• The bovine basic pancreatic trypsin inhibitor (Kunitz inhibitor): a milestone protein.

  2003cited by this paper
• The biology and biochemistry of antichymotrypsin and its potential role as a therapeutic agent.

  1992cited by this paper
• Photocrosslinking of ultra high strength polyethylene fibers

  1990cited by this paper
• SDS Polyacrylamide Gel Electrophoresis of Proteins.

  1984cited by this paper
• Transfer techniques in protein blotting.

  1984cited by this paper
• A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding.

  1976cited by this paper

• Plant-Expression Systems: A New Stage in Production of Biopharmaceutical Preparations

  2021cites this paper
• Plant-Expression Systems: A New Stage in Production of Biopharmaceutical Preparations

  2021cites this paper
• Co-expression With Replicating Vector Overcoming Competitive Effects Derived by a Companion Protease Inhibitor in Plants

  2021cites this paper
• Oral Immunization With a Plant HSP90-SAG1 Fusion Protein Produced in Tobacco Elicits Strong Immune Responses and Reduces Cyst Number and Clinical Signs of Toxoplasmosis in Mice

  2021cites this paper
• Recombinant cystatins in plants.

  2019cites this paper
• Production of Biopharmaceuticals in Nicotiana benthamiana—Axillary Stem Growth as a Key Determinant of Total Protein Yield

  2019cites this paper
• Proteases of Nicotiana benthamiana: an emerging battle for molecular farming.

  2019cites this paper
• Recombinant protein susceptibility to proteolysis in the plant cell secretory pathway is pH‐dependent

  2018cites this paper
• The Impact of Six Critical Impurities on Recombinant Protein Recovery and Purification from Plant Hosts

  2018cites this paper
• pH Gradient Mitigation in the Leaf Cell Secretory Pathway Alters the Defense Response of Nicotiana benthamiana to Agroinfiltration

  2018cites this paper
• Protection des protéines recombinantes sécrétées chez l'hôte d'expression "Nicotiana benthamiana" par expression hétérologue du canal ionique M2 du virus de l'Influenza

  2017cites this paper
• A Chimeric Affinity Tag for Efficient Expression and Chromatographic Purification of Heterologous Proteins from Plants

  2016cites this paper
• An Accessory Protease Inhibitor to Increase the Yield and Quality of a Tumour-Targeting mAb in Nicotiana benthamiana Leaves

  2016cites this paper