c-Myc inhibits myogenic differentiation and myoD expression by a mechanism which can be dissociated from cell transformation.

No abstract is available for this paper.

• Publication year

  1994

• Venue

  Oncogene

• Publication date

  1994-12-01

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 7970710
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Structural analysis of the chicken max gene.

  1994cited by this paper
• Inhibition of transcriptional regulator Yin-Yang-1 by association with c-Myc.

  1993cited by this paper
• Direct role for Myc in transcription initiation mediated by interactions with TFII-I

  1993cited by this paper
• Oncogenic activity of the c-Myc protein requires dimerization with Max.

  1993cited by this paper
• Gene-regulatory properties of Myc helix-loop-helix/leucine zipper mutants: Max-dependent DNA binding and transcriptional activation in yeast correlates with transforming capacity.

  1993cited by this paper
• Mitogenesis of quiescent chick fibroblasts by v-Src: dependence on events at the membrane leading to early changes in AP-1.

  1993cited by this paper
• Myc and Max associate in vivo.

  1992cited by this paper
• Fos and Jun repress transcriptional activation by myogenin and MyoD: the amino terminus of Jun can mediate repression.

  1992cited by this paper
• Transcriptional activation by the human c-Myc oncoprotein in yeast requires interaction with Max

  1992cited by this paper
• Inhibition of muscle differentiation by the adenovirus E1a protein: repression of the transcriptional activating function of the HLH protein Myf-5.

  1992cited by this paper
• Reciprocal Regulation of Adipogenesis by Myc and C/EBPα

  1992cited by this paper
• Functional antagonism between c-Jun and MyoD proteins: a direct physical association.

  1992cited by this paper
• FGF inactivates myogenic helix-loop-helix proteins through phosphorylation of a conserved protein kinase C site in their DNA-binding domains.

  1992cited by this paper
• Myc and Max proteins possess distinct transcriptional activities

  1992cited by this paper
• Interplay between proliferation and differentiation within the myogenic lineage.

  1992cited by this paper
• Amino-terminal domains of c-myc and N-myc proteins mediate binding to the retinoblastoma gene product

  1991cited by this paper
• v-jun oncogene prevents terminal differentiation and suppresses muscle-specific gene expression in ASV-17-infected muscle cells.

  1991cited by this paper
• c-myc inhibition of MyoD and myogenin-initiated myogenic differentiation

  1991cited by this paper
• Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc.

  1991cited by this paper
• Jun inhibits myogenic differentiation.

  1991cited by this paper
• The MYC protein activates transcription of the alpha‐prothymosin gene.

  1991cited by this paper
• The myoD gene family: nodal point during specification of the muscle cell lineage.

  1991cited by this paper
• Ectopic expression of the erythrocyte band 3 anion exchange protein, using a new avian retrovirus vector

  1990cited by this paper
• The protein Id: a negative regulator of helix-loop-helix DNA binding proteins.

  1990cited by this paper
• MyoD induces growth arrest independent of differentiation in normal and transformed cells.

  1990cited by this paper
• New light on Myc and Myb. Part I. Myc.

  1990cited by this paper
• Cell proliferation inhibited by MyoD1 independently of myogenic differentiation

  1990cited by this paper
• The leucine zipper domain of avian cMyc is required for transformation and autoregulation.

  1990cited by this paper
• Neoplastic transformation and tumorigenesis by the human protooncogene MYC.

  1990cited by this paper
• Transformation by activated ras or fos prevents myogenesis by inhibiting expression of MyoD1.

  1989cited by this paper
• Interaction with normal cells suppresses the transformed phenotype of v-myc-transformed quail muscle cells.

  1989cited by this paper
• A small deletion in the carboxy terminus of the viral myc gene renders the virus MC29 partially transformation defective in avian fibroblasts.

  1989cited by this paper
• c-myc antisense transcripts accelerate differentiation and inhibit G1 progression in murine erythroleukemia cells

  1988cited by this paper
• Phorbol ester-induced terminal differentiation is inhibited in human U-937 monoblastic cells expressing a v-myc oncogene.

  1988cited by this paper
• Jun: oncogene and transcriptional regulator.

  1988cited by this paper
• An oligomer complementary to c-myc mRNA inhibits proliferation of HL-60 promyelocytic cells and induces differentiation

  1988cited by this paper
• The oncogenic forms of N-ras or H-ras prevent skeletal myoblast differentiation

  1987cited by this paper
• Adaptor plasmids simplify the insertion of foreign DNA into helper-independent retroviral vectors

  1987cited by this paper
• The myc oncogene: its role in transformation and differentiation.

  1986cited by this paper
• Constitutive c-myc oncogene expression blocks mouse erythroleukaemia cell differentiation but not commitment

  1986cited by this paper
• Serum and fibroblast growth factor inhibit myogenic differentiation through a mechanism dependent on protein synthesis and independent of cell proliferation.

  1986cited by this paper
• Potentiation of growth factor activity by exogenous c-myc expression.

  1986cited by this paper
• Distinctive effects of the viral oncogenes myc, erb, fps, and src on the differentiation program of quail myogenic cells.

  1985cited by this paper
• Quail embryo fibroblasts transformed by four v‐myc‐containing virus isolates show enhanced proliferation but are non tumorigenic.

  1983cited by this paper
• Development of 'revertant' myotubes in cultures of Rous sarcoma virus transformed avian myogenic cells.

  1983cited by this paper
• Immunochemical analysis of myosin heavy chain during avian myogenesis in vivo and in vitro

  1982cited by this paper
• Acetylcholine receptors of muscle grown in vitro.

  1972cited by this paper

• FTO promotes skeletal muscle differentiation and regeneration by regulating m6A-modified c-Myc

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• Cell divisions are not essential for the direct conversion of fibroblasts into neuronal cells

  2015cites this paper
• c-Myc-dependent transcriptional regulation of cell cycle and nucleosomal histones during oligodendrocyte differentiation.

  2014cites this paper
• MYC Is an Early Response Regulator of Human Adipogenesis in Adipose Stem Cells

  2014cites this paper
• Mitochondria as a Potential Regulator of Myogenesis

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• Etude des cellules souches et progénitrices mammaires et de leur contribution à la tumorigenèse : rôle des facteurs de transcription Myc et p53

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• An HMGA2-IGF2BP2 axis regulates myoblast proliferation and myogenesis.

  2012cites this paper
• Investigating the potential interaction of RBM4 withTranslational machinery in C2C12 cells undergoingmyogenic differentiation

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• Transcription Factors and Muscle Differentiation

  2010cites this paper
• Inhibition of cell differentiation: A critical mechanism for MYC-mediated carcinogenesis?

  2009cites this paper
• Increased expression of the pro-apoptotic Bcl2 family member PUMA and apoptosis by the muscle regulatory transcription factor MyoD in response to a variety of stimuli

  2009cites this paper
• Myc’s secret life without Max

  2009cites this paper
• Max-independent functions of Myc in Drosophila melanogaster

  2008cites this paper
• The effects of Ankrd2 alteration indicate its involvement in cell cycle regulation during muscle differentiation.

  2008cites this paper
• c-Myc, Apoptosis, and Disordered Tissue Growth

  2007cites this paper
• CANCER DRUG DISCOVERY AND DEVELOPMENT

  2007influential citation
• Interactions Between Myc- and Cyclin-DependentKinase Inhibitors in Cancer

  2007cites this paper
• Balance of Yin and Yang: ubiquitylation-mediated regulation of p53 and c-Myc.

  2006cites this paper
• Implication des mitochondries dans la biologie musculaire : un rôle clé au cours du développement, de la croissance et de la fonte musculaire

  2006cites this paper
• Mitochondrial activity regulates myoblast differentiation by control of c‐Myc expression

  2006cites this paper
• c-Myc and downstream targets in the pathogenesis and treatment of cancer.

  2006cites this paper
• Inactivation of MAP kinase signalling in Myc Transformed Cells and Rescue by LiCl inhibition of GSK3

  2005cites this paper
• Viral mutations enhance the Max binding properties of the vMyc b-HLH-LZ domain

  2005cites this paper
• A Suv39h‐dependent mechanism for silencing S‐phase genes in differentiating but not in cycling cells

  2004cites this paper
• Phenotypic and morphological characterization of neuroblastoma cells constitutively expressing B-myb

  2004cites this paper
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  2003cites this paper
• c-Myc Is Essential but Not Sufficient for c-Myb-mediated Block of Granulocytic Differentiation*

  2003cites this paper
• The c-MYC oncoprotein as a treatment target in cancer and other disorders of cell growth

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  2001cites this paper
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  2000cites this paper
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  2000cites this paper
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  2000cites this paper
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  1999cites this paper
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  1998cites this paper
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  1998cites this paper
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  1998cites this paper
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  1998cites this paper
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  1998cites this paper
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  1997cites this paper
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  1997cites this paper
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  1997cites this paper
• Cellular commitment and differentiation in the cochlea: potential advances using gene transfer.

  1997cites this paper
• The c-myc story: where we've been, where we seem to be going.

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  1997cites this paper
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• Cell-cycle progression is not essential for c-Myc to block differentiation

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  1995cites this paper