Apparent uncoupling of oncogenicity from fibroblast transformation and apoptosis in a mutant myc gene transduced by feline leukemia virus

No abstract is available for this paper.

• Publication year

  1996

• Venue

  Journal of Virology

• Publication date

  1996-02-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/jvi.70.2.1154-1162.1996PMID 8551576PMCID PMC189924
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Bcl-2 expressed using a retroviral vector is localized primarily in the nuclear membrane and the endoplasmic reticulum of chicken embryo fibroblasts.

  1994cited by this paper
• Expression of mad, mxi1, max and c-myc during induced differentiation of hematopoietic cells: opposite regulation of mad and c-myc.

  1994cited by this paper
• Mutations in the Coding Region of c-myc Occur Frequently in Acquired Immunodeficiency Syndrome-Associated Lymphomas

  1994cited by this paper
• Mutations in the coding region of c-myc occur frequently in acquired immunodeficiency syndrome-associated lymphomas.

  1994cited by this paper
• c-Myc inhibits myogenic differentiation and myoD expression by a mechanism which can be dissociated from cell transformation.

  1994cited by this paper
• Identification of amino acid‐base contacts in the Myc‐DNA complex by site‐specific bromouracil mediated photocrosslinking.

  1994cited by this paper
• Site-specific modulation of c-Myc cotransformation by residues phosphorylated in vivo.

  1994cited by this paper
• Repression of cyclin D1: a novel function of MYC.

  1994cited by this paper
• Genetic determinants of feline leukemia virus-induced lymphoid tumors: patterns of proviral insertion and gene rearrangement

  1994cited by this paper
• Interaction of c‐Myc with the pRb‐related protein p107 results in inhibition of c‐Myc‐mediated transactivation.

  1994cited by this paper
• Binding and suppression of the Myc transcriptional activation domain by p107.

  1994cited by this paper
• Point mutations in the c–Myc transactivation domain are common in Burkitt's lymphoma and mouse plasmacytomas

  1993cited by this paper
• Gene-regulatory properties of Myc helix-loop-helix/leucine zipper mutants: Max-dependent DNA binding and transcriptional activation in yeast correlates with transforming capacity.

  1993cited by this paper
• Functional analysis of the carboxy-terminal transforming region of v-Myc: binding to Max is necessary, but not sufficient, for cellular transformation.

  1993cited by this paper
• Mxi1, a protein that specifically interacts with Max to bind Myc-Max recognition sites.

  1993cited by this paper
• Detection of DNA strand breaks in individual apoptotic cells by the in situ terminal deoxynucleotidyl transferase and nick translation assays.

  1993cited by this paper
• Transactivation of gene expression by Myc is inhibited by mutation at the phosphorylation sites Thr-58 and Ser-62.

  1993cited by this paper
• Overproduction of v-Myc in the nucleus and its excess over Max are not required for avian fibroblast transformation

  1993cited by this paper
• Phosphorylation sites mapping in the N-terminal domain of c-myc modulate its transforming potential.

  1993cited by this paper
• Versatile avian retrovirus vectors.

  1993cited by this paper
• Clustered mutations in the second exon of the MYC gene in sporadic Burkitt's lymphoma.

  1993cited by this paper
• A switch from Myc:Max to Mad:Max heterocomplexes accompanies monocyte/macrophage differentiation.

  1993cited by this paper
• The ornithine decarboxylase gene is a transcriptional target of c-Myc.

  1993cited by this paper
• Mad: a heterodimeric partner for Max that antagonizes Myc transcriptional activity.

  1993cited by this paper
• Induction of apoptosis in fibroblasts by c-myc protein.

  1992cited by this paper
• myc function and regulation.

  1992cited by this paper
• Mutations within the 5' half of the avian retrovirus MC29 v-myc gene alter or abolish transformation of chicken embryo fibroblasts and macrophages

  1992cited by this paper
• Pathogenesis of feline leukemia virus T17: contrasting fates of helper, v-myc, and v-tcr proviruses in secondary tumors

  1992cited by this paper
• Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc.

  1991influential reference
• Amino-terminal domains of c-myc and N-myc proteins mediate binding to the retinoblastoma gene product

  1991cited by this paper
• The MYC protein activates transcription of the alpha‐prothymosin gene.

  1991cited by this paper
• C-myc and the yeast transcription factor PHO4 share a common CACGTG-binding motif.

  1991cited by this paper
• Constitutive c-myc expression in an IL-3-dependent myeloid cell line suppresses cell cycle arrest and accelerates apoptosis.

  1991cited by this paper
• Sequence-specific DNA binding by the c-Myc protein.

  1990cited by this paper
• The leucine zipper domain of avian cMyc is required for transformation and autoregulation.

  1990cited by this paper
• Structural diversity and nuclear protein binding sites in the long terminal repeats of feline leukemia virus

  1990cited by this paper
• An amino-terminal c-myc domain required for neoplastic transformation activates transcription

  1990influential reference
• Domains of human c-myc protein required for autosuppression and cooperation with ras oncogenes are overlapping

  1990cited by this paper
• Structure, origin, and transforming activity of feline leukemia virus-myc recombinant provirus FTT

  1989cited by this paper
• Involvement of the 'leucine zipper' region in the oligomerization and transforming activity of human c-myc protein

  1989influential reference
• Identification of the human c-myc protein nuclear translocation signal

  1988cited by this paper
• A non-AUG translational initiation in c-myc exon 1 generates an N-terminally distinct protein whose synthesis is disrupted in Burkitt's lymphomas.

  1988cited by this paper
• Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase.

  1988cited by this paper
• Transforming potential of a myc-containing variant of feline leukemia virus in vitro in early-passage feline cells

  1987cited by this paper
• The transforming activity of the chicken c-myc gene can be potentiated by mutations.

  1987influential reference
• The role of feline leukaemia virus in naturally occurring leukaemias.

  1987cited by this paper
• Definition of regions in human c-myc that are involved in transformation and nuclear localization

  1987cited by this paper
• Retroviral transduction of T-cell antigen receptor β-chain and myc genes

  1987cited by this paper
• Evolutionarily conserved regions of the human c-myc protein can be uncoupled from transforming activity.

  1987cited by this paper
• Adaptor plasmids simplify the insertion of foreign DNA into helper-independent retroviral vectors

  1987cited by this paper
• Retroviral transduction of T-cell antigen receptor beta-chain and myc genes.

  1987cited by this paper
• Conservation of the c-myc coding sequence in transduced feline v-myc genes.

  1986cited by this paper
• Transformation of quail embryo fibroblasts by a retrovirus carrying a normal human c‐myc gene.

  1986cited by this paper
• Amino acid sequences common to rapidly degraded proteins: the PEST hypothesis.

  1986cited by this paper
• Nucleotide sequence of a transduced myc gene from a defective feline leukemia provirus

  1985cited by this paper
• Transduction and rearrangement of the myc gene by feline leukaemia virus in naturally occurring T-cell leukaemias

  1984cited by this paper
• Spontaneous mammary adenocarcinomas in transgenic mice that carry and express MTV/myc fusion genes.

  1984cited by this paper
• A recovered avian myelocytomatosis virus that induces lymphomas in chickens: pathogenic properties and their molecular basis.

  1983cited by this paper
• Altered nucleotide sequences of a translocated c-myc gene in Burkitt lymphoma

  1983cited by this paper
• Cloning in single-stranded bacteriophage as an aid to rapid DNA sequencing.

  1980cited by this paper
• Characterisation of a tumour-specific antigen on the surface of feline lymphosarcoma cells

  1978cited by this paper
• Recovery of avian sarcoma virus from tumors induced by transformation- defective mutants

  1977cited by this paper
• Development, characterization, and viral susceptibility of a feline (Felis catus) renal cell line (CRFK)

  1973cited by this paper
• A transmissible virus-induced lymphocytic leukemia of the cat.

  1969cited by this paper

• Molecular pathogenesis of feline leukemia virus-induced malignancies: insertional mutagenesis.

  2008cites this paper
• A novel form of the RelA nuclear factor kappaB subunit is induced by and forms a complex with the proto-oncogene c-Myc.

  2002cites this paper
• Protein stabilization: a common consequence of mutations in independently derived v-Myc alleles

  1999cites this paper
• The DF-1 chicken fibroblast cell line: transformation induced by diverse oncogenes and cell death resulting from infection by avian leukosis viruses.

  1998cites this paper
• [Apoptosis in virus infections of animals: a survey].

  1998cites this paper
• Comparative analysis of the structure and function of the chicken c-myc and v-myc genes: v-myc is a more potent inducer of cell proliferation and apoptosis than c-myc.

  1996cites this paper
• Multiple phenotypes associated with Myc-induced transformation of chick embryo fibroblasts can be dissociated by a basic region mutation.

  1996cites this paper