Different Leishmania Species Drive Distinct Neutrophil Functions.

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Trends in Parasitology

• Publication date

  2016-05-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.pt.2016.02.003PMID 26944469
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The Nlrp3 inflammasome, IL‐1β, and neutrophil recruitment are required for susceptibility to a nonhealing strain of Leishmania major in C57BL/6 mice

  2016cited by this paper
• Spatially Distinct Neutrophil Responses within the Inflammatory Lesions of Pneumonic Plague

  2015cited by this paper
• Classical ROS-dependent and early/rapid ROS-independent release of Neutrophil Extracellular Traps triggered by Leishmania parasites

  2015cited by this paper
• Exposure to Leishmania braziliensis Triggers Neutrophil Activation and Apoptosis

  2015cited by this paper
• Are Neutrophil Extracellular Traps Playing a Role in the Parasite Control in Active American Tegumentary Leishmaniasis Lesions?

  2015cited by this paper
• Rapid Sequestration of Leishmania mexicana by Neutrophils Contributes to the Development of Chronic Lesion

  2015influential reference
• Lymphocytic Choriomeningitis Virus Expands a Population of NKG2D+CD8+ T Cells That Exacerbates Disease in Mice Coinfected with Leishmania major

  2015cited by this paper
• Interactions between Neutrophils and Leishmania braziliensis Amastigotes Facilitate Cell Activation and Parasite Clearance

  2015cited by this paper
• Permissive and protective roles for neutrophils in leishmaniasis

  2015cited by this paper
• Neutrophil Extracellular Traps Downregulate Lipopolysaccharide-Induced Activation of Monocyte-Derived Dendritic Cells

  2014cited by this paper
• Strategies to Overcome Antileishmanial Drugs Unresponsiveness

  2014cited by this paper
• Neutrophils at work

  2014cited by this paper
• 3′-Nucleotidase/Nuclease Activity Allows Leishmania Parasites To Escape Killing by Neutrophil Extracellular Traps

  2014cited by this paper
• Neutrophils have a protective role during early stages of Leishmania amazonensis infection in BALB/c mice

  2014cited by this paper
• Site-Dependent Recruitment of Inflammatory Cells Determines the Effective Dose of Leishmania major

  2014cited by this paper
• Lundep, a Sand Fly Salivary Endonuclease Increases Leishmania Parasite Survival in Neutrophils and Inhibits XIIa Contact Activation in Human Plasma

  2014cited by this paper
• Social networking of human neutrophils within the immune system.

  2014cited by this paper
• Neutrophil recruitment and function in health and inflammation

  2013cited by this paper
• Arginase Activity - A Marker of Disease Status in Patients with Visceral Leishmaniasis in Ethiopia

  2013cited by this paper
• Diverse novel functions of neutrophils in immunity, inflammation, and beyond

  2013cited by this paper
• Leishmania amazonensis Amastigotes Trigger Neutrophil Activation but Resist Neutrophil Microbicidal Mechanisms

  2013cited by this paper
• Whatˈs your age again? Determination of human neutrophil half‐lives revisited

  2013cited by this paper
• Crosstalk between neutrophils and dendritic cells: a context‐dependent process

  2013cited by this paper
• Neutrophils control the magnitude and spread of the immune response in a thromboxane A2-mediated process

  2013cited by this paper
• Neutrophil depletion impairs natural killer cell maturation, function, and homeostasis

  2012cited by this paper
• Leishmaniasis Worldwide and Global Estimates of Its Incidence

  2012cited by this paper
• Efficient Capture of Infected Neutrophils by Dendritic Cells in the Skin Inhibits the Early Anti-Leishmania Response

  2012cited by this paper
• The influence of early neutrophil-Leishmania interactions on the host immune response to infection

  2012cited by this paper
• A hypomorphic mutation in the Gfi1 transcriptional repressor results in a novel form of neutropenia

  2012cited by this paper
• Local Increase of Arginase Activity in Lesions of Patients with Cutaneous Leishmaniasis in Ethiopia

  2012cited by this paper
• Neutrophil function: from mechanisms to disease.

  2012cited by this paper
• Amine‐reactive OVA multimers for auto‐vaccination against cytokines and other mediators: perspectives illustrated for GCP‐2 in L. major infection

  2011cited by this paper
• B–helper neutrophils stimulate immunoglobulin diversification and production in the marginal zone of the spleen

  2011cited by this paper
• Neutrophils in the activation and regulation of innate and adaptive immunity

  2011cited by this paper
• Doubts concerning the recently reported human neutrophil lifespan of 5.4 days.

  2011cited by this paper
• Neutrophil survival and c-kit(+)-progenitor proliferation in Staphylococcus aureus-infected skin wounds promote resolution.

  2011cited by this paper
• Neutrophils Influence the Level of Antigen Presentation during the Immune Response to Protein Antigens in Adjuvants

  2010cited by this paper
• Leukocytes Infiltrate the Skin and Draining Lymph Nodes in Response to the Protozoan Leishmania infantum chagasi

  2010cited by this paper
• Immunity to Lutzomyia intermedia Saliva Modulates the Inflammatory Environment Induced by Leishmania braziliensis

  2010cited by this paper
• Neutrophil kinetics in health and disease

  2010cited by this paper
• In vivo labeling with 2H2O reveals a human neutrophil lifespan of 5.4 days.

  2010cited by this paper
• Leishmania donovani promastigotes evade the antimicrobial activity of neutrophil extracellular traps

  2010influential reference
• Type I IFN Receptor Regulates Neutrophil Functions and Innate Immunity to Leishmania Parasites

  2010cited by this paper
• Leishmania amazonensis promastigotes induce and are killed by neutrophil extracellular traps

  2009influential reference
• Vector Transmission of Leishmania Abrogates Vaccine-Induced Protective Immunity

  2009cited by this paper
• Neutrophils and Macrophages Cooperate in Host Resistance against Leishmania braziliensis Infection1

  2009cited by this paper
• IL-17 Promotes Progression of Cutaneous Leishmaniasis in Susceptible Mice1

  2009cited by this paper
• The Prominent Role of Neutrophils during the Initial Phase of Infection by Leishmania Parasites

  2009cited by this paper
• Proteophosophoglycans Regurgitated by Leishmania-Infected Sand Flies Target the L-Arginine Metabolism of Host Macrophages to Promote Parasite Survival

  2009cited by this paper
• Neutrophil granulocytes as host cells and transport vehicles for intracellular pathogens: apoptosis as infection-promoting factor.

  2008cited by this paper
• In Vivo Imaging Reveals an Essential Role for Neutrophils in Leishmaniasis Transmitted by Sand Flies

  2008cited by this paper
• Quantification of the infectious dose of Leishmania major transmitted to the skin by single sand flies

  2008cited by this paper
• Neutrophils Activate Macrophages for Intracellular Killing of Leishmania major through Recruitment of TLR4 by Neutrophil Elastase1

  2007cited by this paper
• Neutrophils Contribute to Development of a Protective Immune Response during Onset of Infection with Leishmania donovani

  2007cited by this paper
• Leishmania major induces distinct neutrophil phenotypes in mice that are resistant or susceptible to infection

  2007cited by this paper
• Nonhealing Infection despite Th1 Polarization Produced by a Strain of Leishmania major in C57BL/6 Mice

  2005cited by this paper
• Saliva from Lutzomyia longipalpis Induces CC Chemokine Ligand 2/Monocyte Chemoattractant Protein-1 Expression and Macrophage Recruitment1

  2005cited by this paper
• Neutrophils rapidly migrate via lymphatics after Mycobacterium bovis BCG intradermal vaccination and shuttle live bacilli to the draining lymph nodes.

  2005cited by this paper
• Complement C3 is required for the progression of cutaneous lesions and neutrophil attraction in Leishmania major infection

  2005cited by this paper
• Of Mice and Not Men: Differences between Mouse and Human Immunology

  2004cited by this paper
• Neutrophil Extracellular Traps Kill Bacteria

  2004cited by this paper
• Cutting Edge: Neutrophil Granulocyte Serves as a Vector for Leishmania Entry into Macrophages1

  2004cited by this paper
• Gender dimorphism in differential peripheral blood leukocyte counts in mice using cardiac, tail, foot, and saphenous vein puncture methods

  2003cited by this paper
• Inhibition of the Spontaneous Apoptosis of Neutrophil Granulocytes by the Intracellular Parasite Leishmania major1

  2002cited by this paper
• Leishmania Promastigotes Release a Granulocyte Chemotactic Factor and Induce Interleukin-8 Release but Inhibit Gamma Interferon-Inducible Protein 10 Production by Neutrophil Granulocytes

  2002cited by this paper
• Intracellular Survival of Leishmania major in Neutrophil Granulocytes after Uptake in the Absence of Heat-Labile Serum Factors

  2002cited by this paper
• Chemokines, natural killer cells and granulocytes in the early course of Leishmania major infection in mice

  2001cited by this paper
• Insertion of enhanced green fluorescent protein into the lysozyme gene creates mice with green fluorescent granulocytes and macrophages.

  2000cited by this paper
• An Immunomodulatory Function for Neutrophils During the Induction of a CD4+ Th2 Response in BALB/c Mice Infected with Leishmania major1

  2000cited by this paper
• Insertion of enhanced green fluorescent protein into the lysozyme gene creates mice with green fluorescent granulocytes and macrophages

  2000cited by this paper
• Neutrophil-derived proteins: selling cytokines by the pound.

  1999cited by this paper
• Genetic susceptibility to leishmanial infections: studies in mice and man

  1996cited by this paper
• Differences in the onset of the inflammatory response to cutaneous leishmaniasis in resistant and susceptible mice

  1992cited by this paper

• An overview of host immune responses against Leishmania spp. infections

  2025cites this paper
• Redressing the Balance Against B Regulatory Cells: Novel Immunotherapeutic Target in Leishmaniasis

  2025cites this paper
• Mapping the immune landscape in South Asian post kala-azar dermal leishmaniasis

  2025cites this paper
• Detection of LPG2 and GP63 genes sequencing in patients with cutaneous leishmaniasis

  2025cites this paper
• Transdifferentiation of neutrophils facilitates the establishment of infection by Leishmania donovani parasites

  2025cites this paper
• Neutrophil activation, acute lung injury and disease severity in Plasmodium knowlesi malaria

  2024cites this paper
• Leishmania infantum infection modulates messenger RNA, microRNA and long non-coding RNA expression in human neutrophils in vitro

  2024cites this paper
• Distinct neutrophil effector functions in response to different isolates of Leishmania aethiopica

  2024cites this paper
• Anti-inflammatory and immunomodulatory effects of mesenchymal stem cell therapy on parasitic drug resistance

  2024cites this paper
• Activation of neutrophils excels the therapeutic potential of Mycobacterium indicus pranii and heat‐induced promastigotes against antimony‐resistant Leishmania donovani infection

  2024cites this paper
• Neutrophil extracellular traps formation: effect of Leishmania major promastigotes and salivary gland homogenates of Phlebotomus papatasi in human neutrophil culture

  2024influential citation
• Unleashing the role of potential adjuvants in leishmaniasis.

  2024cites this paper
• Role of neutrophils in the pathogenesis of Post Kala-azar Dermal Leishmaniasis (PKDL)

  2024cites this paper
• Exploring Bioinformatics Solutions for Improved Leishmaniasis Diagnostic Tools: A Review

  2024cites this paper
• MR1 blockade drives differential impact on integrative signatures based on circuits of circulating immune cells and soluble mediators in visceral leishmaniasis

  2024cites this paper
• Leishmania infantum Axenic Amastigotes Induce Human Neutrophil Extracellular Traps and Resist NET-Mediated Killing

  2023cites this paper
• Balancing the functions of DNA extracellular traps in intracellular parasite infections: implications for host defense, disease pathology and therapy

  2023cites this paper
• Leishmaniasis: Immune Cells Crosstalk in Macrophage Polarization

  2023cites this paper
• Comparison of Pro-inflammatory Gene Expression Profile in Spleen and Peripheral Blood Neutrophils of BALB/C Mice Infected with Leishmania Major

  2022cites this paper
• Leishmania major Strain-Dependent Macrophage Activation Contributes to Pathogenicity in the Absence of Lymphocytes

  2022cites this paper
• The role of mucosal-associated invariant T cells in visceral leishmaniasis

  2022cites this paper
• Following successful anti-leishmanial treatment, neutrophil counts, CD10 expression and phagocytic capacity remain reduced in visceral leishmaniasis patients co-infected with HIV

  2022cites this paper
• In and out: Leishmania metastasis by hijacking lymphatic system and migrating immune cells

  2022cites this paper
• Opinion Article: NK Cells in Cutaneous Leishmaniasis: Protection or Damage?

  2022cites this paper
• Leishmania infantum Infection of Primary Human Myeloid Cells

  2022cites this paper
• A Mouse Model of Ulcerative Cutaneous Leishmaniasis by Leishmania (Viannia) panamensis to Investigate Infection, Pathogenesis, Immunity, and Therapeutics

  2022cites this paper
• Major Molecular Factors Related to Leishmania Pathogenicity

  2022cites this paper
• Exploring IL-17 gene promoter polymorphisms in canine leishmaniasis.

  2022cites this paper
• Leishmania infantum Defective in Lipophosphoglycan Biosynthesis Interferes With Activation of Human Neutrophils

  2022cites this paper
• Immune Responses in Leishmaniasis: An Overview

  2022cites this paper
• Pathogenic Exploitation of Lymphatic Vessels

  2022cites this paper
• Insight Into the Long Noncoding RNA and mRNA Coexpression Profile in the Human Blood Transcriptome Upon Leishmania infantum Infection

  2022cites this paper
• The c-MET receptor tyrosine kinase contributes to neutrophil-driven pathology in cutaneous leishmaniasis

  2022cites this paper
• Leukocytes and Albumin in Canine Leishmaniasis

  2021cites this paper
• Leishmaniasis

  2021cites this paper
• Understanding the immune responses involved in mediating protection or immunopathology during leishmaniasis.

  2021cites this paper
• Host immune response against leishmaniasis and parasite persistence strategies: A review and assessment of recent research.

  2021cites this paper
• Visualizing the In Vivo Dynamics of Anti-Leishmania Immunity: Discoveries and Challenges

  2021cites this paper
• Leishmania Parasites Drive PD-L1 Expression in Mice and Human Neutrophils With Suppressor Capacity

  2021cites this paper
• Detection of Leishmania infantum amastigotes in neutrophil from peripheral blood in a naturally infected dog.

  2021cites this paper
• The Paradox of a Phagosomal Lifestyle: How Innate Host Cell-Leishmania amazonensis Interactions Lead to a Progressive Chronic Disease

  2021cites this paper
• Neutrophil Activation: Influence of Antimony Tolerant and Susceptible Clinical Strains of L. (V.) panamensis and Meglumine Antimoniate

  2021cites this paper
• Anti-Leishmania activity of mucosal-associated invariant T-cells

  2021cites this paper
• Determinants of Innate Immunity in Visceral Leishmaniasis and Their Implication in Vaccine Development

  2021cites this paper
• Purinergic Enhancement of Anti-Leishmanial Effector Functions of Neutrophil Granulocytes

  2021influential citation
• Protective immune response mediated by neutrophils in experimental visceral leishmaniasis is enhanced by IL-32γ.

  2021cites this paper
• Leukocyte Behavior in Mesenteric Microcirculation upon Experimental By Leishmania Spp. in BALB/c Mice

  2021cites this paper
• Exploring the paradox of defense between host and Leishmania parasite.

  2021cites this paper
• A further investigation of the leishmaniosis outbreak in Madrid (Spain): low-infectivity phenotype of the Leishmania infantum BOS1FL1 isolate to establish infection in canine cells.

  2020cites this paper
• TLR7 Sensing by Neutrophils Is Critical for the Control of Cutaneous Leishmaniasis.

  2020cites this paper
• Antiparasitic Behavior of Trifluoromethylated Pyrazole 2-Amino-1,3,4-thiadiazole Hybrids and Their Analogues: Synthesis and Structure-Activity Relationship

  2020cites this paper
• Leishmania Immunity: Advancing Immunotherapy and Vaccine Development

  2020cites this paper
• Immunity of Parasitic Infections of the Liver

  2020cites this paper
• LPG2 Gene Duplication in Leishmania infantum: A Case for CRISPR-Cas9 Gene Editing

  2020cites this paper
• Leishmaniasis immunopathology—impact on design and use of vaccines, diagnostics and drugs

  2020cites this paper
• Mouse Models and Tools for the in vivo Study of Neutrophils

  2020cites this paper
• Apoptotic mimicry as a strategy for the establishment of parasitic infections: parasite- and host-derived phosphatidylserine as key molecule

  2020cites this paper
• Essential Role of Neutrophils in the Protective Immune Response Induced by a Live Attenuated Leishmania Vaccine

  2020cites this paper
• Neutrophils and Visceral Leishmaniasis: Impact on innate immune response and cross‐talks with macrophages and dendritic cells

  2020cites this paper
• Inflammation following trypanosome infection and persistence in the skin.

  2020cites this paper
• Macrophages as host, effector and immunoregulatory cells in leishmaniasis: Impact of tissue micro-environment and metabolism

  2020cites this paper
• Immune response to Leishmania mexicana: the host parasite relationship.

  2020cites this paper
• Leishmania donovani Induces Autophagy in Human Blood–Derived Neutrophils

  2019cites this paper
• TLR2 Signaling in Skin Nonhematopoietic Cells Induces Early Neutrophil Recruitment in Response to Leishmania major Infection.

  2019cites this paper
• Protective or Detrimental? Understanding the Role of Host Immunity in Leishmaniasis

  2019cites this paper
• Profiles of Local and Systemic Inflammation in the Outcome of Treatment of Human Cutaneous Leishmaniasis Caused by Leishmania (Viannia)

  2019cites this paper
• Avaliação da interação entre neutrófilos humanos infectados por Leishmania amazonensis ou Leishmania braziliensis com células dendríticas: impacto dos receptores de adenosina

  2019cites this paper
• Role of the lipoxin A4 receptor in the development of neutrophil extracellular traps in Leishmania infantum infection

  2019cites this paper
• Infection of Human Neutrophils With Leishmania infantum or Leishmania major Strains Triggers Activation and Differential Cytokines Release

  2019influential citation
• Neutrophil properties in healthy and Leishmania infantum-naturally infected dogs

  2019cites this paper
• Macrophage ghost entrapped amphotericin B: a novel delivery strategy towards experimental visceral leishmaniasis

  2018cites this paper
• Leishmania Hijacks Myeloid Cells for Immune Escape

  2018cites this paper
• Analysis of the Antigenic and Prophylactic Properties of the Leishmania Translation Initiation Factors eIF2 and eIF2B in Natural and Experimental Leishmaniasis

  2018cites this paper
• Inhibition of Neutrophil-Mediated Oxidative Burst Leishmania

  2018cites this paper
• Avaliação da eficácia e imunogenicidade de extratos antigênicos homólogos e heterólogos como vacinas contra leishmaniose cutânea murina causada por Leishmania amazonensis

  2018cites this paper
• Resistance of Leishmania (Viannia) Panamensis to Meglumine Antimoniate or Miltefosine Modulates Neutrophil Effector Functions

  2018cites this paper
• Neutrophils enhance early Trypanosoma brucei infection onset

  2018cites this paper
• Biomarkers of Cutaneous Leishmaniasis

  2018cites this paper
• How to master the host immune system? Leishmania parasites have the solutions!

  2017cites this paper
• Heme Drives Oxidative Stress-Associated Cell Death in Human Neutrophils Infected with Leishmania infantum

  2017cites this paper
• IL-4Rα Signaling in Keratinocytes and Early IL-4 Production Are Dispensable for Generating a Curative T Helper 1 Response in Leishmania major-Infected C57BL/6 Mice

  2017cites this paper
• Canine neutrophils activate effector mechanisms in response to Leishmania infantum.

  2017cites this paper
• Survival Mechanisms Used by Some Leishmania Species to Escape Neutrophil Killing

  2017cites this paper
• Frontline Science: Leishmania mexicana amastigotes can replicate within neutrophils

  2017cites this paper
• The Equivocal Role of Th17 Cells and Neutrophils on Immunopathogenesis of Leishmaniasis

  2017influential citation
• Infection and Activation of Human Neutrophils with Fluorescent Leishmania infantum.

  2016cites this paper
• A Subset of Neutrophils Expressing Markers of Antigen-Presenting Cells in Human Visceral Leishmaniasis.

  2016cites this paper
• Neutrophil responses to infection with Leishmania parasites: MHC class II-expression and parasite life-stage interactions

  2016cites this paper
• Visceral Leishmaniasis Patients Display Altered Composition and Maturity of Neutrophils as well as Impaired Neutrophil Effector Functions

  2016cites this paper
• Recent advances in microscopic techniques for visualizing leukocytes in vivo

  2016cites this paper
• Role of pro-inflammatory cytokine IL-17 in Leishmania pathogenesis and in protective immunity by Leishmania vaccines.

  2016cites this paper
• Twin Attributes of Tyrosyl-tRNA Synthetase of Leishmania donovani

  2016cites this paper
• Leishmania exosomes and other virulence factors: Impact on innate immune response and macrophage functions.

  2016cites this paper