Platelet Activation by Low Density Lipoprotein and High Density Lipoprotein

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Pathophysiology of Haemostasis and Thrombosis

• Publication date

  2006-07-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1159/000093220PMID 16877876
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Effect of Oxidation on the Platelet-Activating Properties of Low-Density Lipoprotein

  2005cited by this paper
• Binding of Low Density Lipoprotein to Platelet Apolipoprotein E Receptor 2′ Results in Phosphorylation of p38MAPK *

  2004cited by this paper
• HDL3 induces cyclooxygenase-2 expression and prostacyclin release in human endothelial cells via a p38 MAPK/CRE-dependent pathway: effects on COX-2/PGI-synthase coupling.

  2004cited by this paper
• Site-specific phosphorylation of platelet focal adhesion kinase by low-density lipoprotein.

  2003cited by this paper
• Expression of Human Scavenger Receptor B1 on and in Human Platelets

  2003cited by this paper
• Low-density lipoprotein and its effect on human blood platelets

  2003cited by this paper
• Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1) Inhibits Low Density Lipoprotein-induced Signaling in Platelets*

  2003cited by this paper
• Circulating activated platelets exacerbate atherosclerosis in mice deficient in apolipoprotein E

  2003cited by this paper
• p38 mitogen‐activated protein kinase dephosphorylation is regulated by protein phosphatase 2A in human platelets activated by collagen

  2002cited by this paper
• Increased Superoxide Anion Production by Platelets in Hypercholesterolemic Patients

  2002cited by this paper
• Platelet Activation by the apoB/E Receptor-binding Domain of LDL

  2002cited by this paper
• Platelet HDL3 binding sites are not related to integrin αIIbβ3 (GPIIb–IIIa)

  2001cited by this paper
• Suppression of Endothelial Cell Apoptosis by High Density Lipoproteins (HDL) and HDL-associated Lysosphingolipids*

  2001cited by this paper
• Src Homology 2 Domain-Containing Protein-Tyrosine Phosphatases, SHP-1 and SHP-2, Are Required for Platelet Endothelial Cell Adhesion Molecule-1/CD31-Mediated Inhibitory Signaling1

  2001cited by this paper
• Src Family Kinases Are Required for Integrin-mediated but Not for G Protein-coupled Receptor Stimulation of Focal Adhesion Kinase Autophosphorylation at Tyr-397*

  2001cited by this paper
• Upregulation of CD40 and CD40 Ligand (CD154) in Patients With Moderate Hypercholesterolemia

  2001cited by this paper
• Structural, biochemical and signaling properties of the low-density lipoprotein receptor gene family.

  2001cited by this paper
• Plasma Lipoproteins, Hemostasis and Thrombosis

  2001cited by this paper
• Platelet HDL(3) binding sites are not related to integrin alpha(IIb)beta(3) (GPIIb-IIIa).

  2001cited by this paper
• Low-density lipoprotein (LDL) binds to a G-protein coupled receptor in human platelets. Evidence that the proaggregatory effect induced by LDL is modulated by down-regulation of binding sites and desensitization of its mediated signaling.

  2001cited by this paper
• Normal high density lipoprotein inhibits three steps in the formation of mildly oxidized low density lipoprotein: steps 2 and 3.

  2000cited by this paper
• High-density lipoproteins protect endothelial cells from tumor necrosis factor-alpha-induced apoptosis.

  2000cited by this paper
• Normal high density lipoprotein inhibits three steps in the formation of mildly oxidized low density lipoprotein: step 1.

  2000cited by this paper
• Binding of High Density Lipoprotein (HDL) and Discoidal Reconstituted HDL to the HDL Receptor Scavenger Receptor Class B Type I*

  2000cited by this paper
• High-Density Lipoproteins Protect Endothelial Cells from Tumor Necrosis Factor-α-Induced Apoptosis

  2000cited by this paper
• Regulatory effects of HDL on smooth muscle cell prostacyclin release.

  1999cited by this paper
• Low-density lipoprotein enhances platelet secretion via integrin-alphaIIbbeta3-mediated signaling.

  1999cited by this paper
• Focal adhesion kinase promotes phospholipase C-γ1 activity

  1999cited by this paper
• Thrombin‐induced association of SHP‐2 with multiple tyrosine‐phosphorylated proteins in human platelets

  1999cited by this paper
• Low Density Lipoprotein Phosphorylates the Focal Adhesion-associated Kinase p125FAK in Human Platelets Independent of Integrin αIIbβ3 *

  1999cited by this paper
• Low-Density Lipoprotein Enhances Platelet Secretion Via Integrin-αIIbβ3–Mediated Signaling

  1999cited by this paper
• Bombesin and Platelet-derived Growth Factor Induce Association of Endogenous Focal Adhesion Kinase with Src in Intact Swiss 3T3 Cells*

  1999cited by this paper
• Low density lipoprotein phosphorylates the focal adhesion-associated kinase p125(FAK) in human platelets independent of integrin alphaIIb beta3.

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• Early Platelet Activation by Low Density Lipoprotein via p38MAP Kinase

  1999cited by this paper
• Complex formation with focal adhesion kinase: A mechanism to regulate activity and subcellular localization of Src kinases.

  1999cited by this paper
• Focal adhesion kinase promotes phospholipase C-gamma1 activity.

  1999cited by this paper
• Mechanisms for regulating platelet high density lipoprotein type3 binding sites: evidence that binding sites are downregulated by a protein kinase C-dependent mechanism.

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• Lipoprotein physiology.

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• Platelet Activity In Vivo in Hyperlipoproteinemia – Importance of Combined Hyperlipidemia

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• Multiple Grb2-Mediated Integrin-Stimulated Signaling Pathways to ERK2/Mitogen-Activated Protein Kinase: Summation of Both c-Src- and Focal Adhesion Kinase-Initiated Tyrosine Phosphorylation Events

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• Platelet integrin alpha IIb beta 3 (GPIIb-IIIa) is not implicated in the binding of LDL to intact resting platelets.

  1997cited by this paper
• Low-density lipoproteins inhibit the Na+/H+ antiport in human platelets. A novel mechanism enhancing platelet activity in hypercholesterolemia.

  1997cited by this paper
• Apolipoprotein E Inhibits Platelet Aggregation through the L-Arginine:Nitric Oxide Pathway

  1997cited by this paper
• Characterization of Phosphotyrosine Binding Motifs in the Cytoplasmic Domain of Platelet/Endothelial Cell Adhesion Molecule-1 (PECAM-1) That Are Required for the Cellular Association and Activation of the Protein-tyrosine Phosphatase, SHP-2*

  1997cited by this paper
• Focal Adhesion Kinase Overexpression Enhances Ras-dependent Integrin Signaling to ERK2/Mitogen-activated Protein Kinase through Interactions with and Activation of c-Src*

  1997cited by this paper
• Platelet endothelial cell adhesion molecule‐1 is a major SH‐PTP2 binding protein in vascular endothelial cells

  1997cited by this paper
• Diabetes mellitus, hypercholesterolemia, and hypertension but not vascular disease per se are associated with persistent platelet activation in vivo. Evidence derived from the study of peripheral arterial disease.

  1997cited by this paper
• Platelet Integrin αIIbβ3 (GPIIb-IIIa) Is Not Implicated in the Binding of LDL to Intact Resting Platelets

  1997cited by this paper
• The Protein-tyrosine Phosphatase SHP-2 Associates with Tyrosine-phosphorylated Adhesion Molecule PECAM-1 (CD31)*

  1997cited by this paper
• Reversal by high-density lipoprotein of the effect of oxidized low-density lipoprotein on nitric oxide synthase protein expression in human platelets.

  1996cited by this paper
• High Density Lipoproteins Enhance the Na+/H+ Antiport in Human Platelets

  1996cited by this paper
• Role for p38 Mitogen-activated Protein Kinase in Platelet Aggregation Caused by Collagen or a Thromboxane Analogue (*)

  1996cited by this paper
• Evidence for in vivo phosphorylation of the Grb2 SH2-domain binding site on focal adhesion kinase by Src-family protein-tyrosine kinases

  1996cited by this paper
• Inhibition of ADP-induced platelet aggregation by apoE is not mediated by membrane cholesterol depletion.

  1996cited by this paper
• Phosphorylation of Tyrosine 397 in Focal Adhesion Kinase Is Required for Binding Phosphatidylinositol 3-Kinase*

  1996cited by this paper
• Thrombin Induces Activation of p38 MAP Kinase in Human Platelets (*)

  1995cited by this paper
• HDL3 activates phospholipase D in normal but not in glycoprotein IIb/IIIa-deficient platelets.

  1995cited by this paper
• Inhibition of ADP-induced platelet aggregation by apoE is not mediated by membrane cholesterol depletion.

  1995cited by this paper
• Cytosolic Phospholipase A2 Is Phosphorylated in Collagen- and Thrombin-stimulated Human Platelets Independent of Protein Kinase C and Mitogen-activated Protein Kinase (*)

  1995cited by this paper
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• Pro-inflammatory Cytokines and Environmental Stress Cause p38 Mitogen-activated Protein Kinase Activation by Dual Phosphorylation on Tyrosine and Threonine (*)

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  1994cited by this paper
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  1993cited by this paper
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  1993cited by this paper
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  1992cited by this paper
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