Higher expression of serotonin 5-HT(2A) receptors in the postmortem brains of teenage suicide victims.

No abstract is available for this paper.

• Publication year

  2002

• Venue

  American Journal of Psychiatry

• Publication date

  2002-03-01

• Fields of study

  Medicine, Psychology

• Identifiers
  DOI 10.1176/APPI.AJP.159.3.419PMID 11870006
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Association of polymorphism of serotonin 2A receptor gene with suicidal ideation in major depressive disorder.

  2000cited by this paper
• Abnormalities in 5‐HT2A receptor mRNA expression in frontal cortex of chronic elderly schizophrenics with varying histories of neuroleptic treatment

  2000cited by this paper
• Segregation of serotonin 5‐HT2A and 5‐HT3 receptors in inhibitory circuits of the primate cerebral cortex

  2000cited by this paper
• Central 5-HT(1) and 5-HT(2) binding sites in transgenic mice with reduced glucocorticoid receptor number.

  2000cited by this paper
• Suicide : biopsychosocial approaches

  1998cited by this paper
• Localization of 5-HT2A receptor in rat cerebral cortex and olfactory system revealed by immunohistochemistry using two antibodies raised in rabbit and chicken.

  1998cited by this paper
• 5-Hydroxytryptamine2A serotonin receptors in the primate cerebral cortex: possible site of action of hallucinogenic and antipsychotic drugs in pyramidal cell apical dendrites.

  1998cited by this paper
• The suicide brain: a review of postmortem receptor/transporter binding studies.

  1998cited by this paper
• Quantitation of 5HT2A receptor mRNA in human postmortem brain using competitive RT‐PCR

  1998cited by this paper
• Benzodiazepine receptors in the post-mortem brain of suicide victims and schizophrenic subjects.

  1997cited by this paper
• Serotonin induces excitatory postsynaptic potentials in apical dendrites of neocortical pyramidal cells.

  1997cited by this paper
• Decreased 5-HT1A and increased 5-HT2A receptor binding after chronic corticosterone associated with a behavioural indication of depression but not anxiety.

  1997cited by this paper
• Serotonin 5‐HT2A receptors are expressed on pyramidal cells and interneurons in the rat cortex

  1997cited by this paper
• Correlation of suicidal and violent behavior in different diagnostic categories in hospitalized adolescent patients.

  1995cited by this paper
• Platelet serotonin-2A receptors: a potential biological marker for suicidal behavior.

  1995cited by this paper
• Serotonergic markers in platelets of patients with major depression: upregulation of 5-HT2 receptors.

  1995cited by this paper
• Altered hypothalamic-pituitary-adrenocortical regulation in healthy subjects at high familial risk for affective disorders.

  1995cited by this paper
• Primary Structure of the Human Platelet Serotonin 5‐HT2A Receptor: Identity with Frontal Cortex Serotonin 5‐HT2A Receptor

  1994cited by this paper
• Differential effect of subchronic dexamethasone treatment on serotonin-2 and beta-adrenergic receptors in the rat cerebral cortex and hippocampus.

  1993cited by this paper
• Adolescent psychiatric inpatients' risk of suicide attempt at 6-month follow-up.

  1993cited by this paper
• 5-HT uptake sites and 5-HT2 receptors in brain of antidepressant-free suicide victims/depressives: increase in 5-HT2 sites in cortex and amygdala.

  1993cited by this paper
• The Structured Clinical Interview for DSM-III-R (SCID). I: History, rationale, and description.

  1992cited by this paper
• Aggression, suicidality, and serotonin.

  1992cited by this paper
• Drugs of abuse: anatomy, pharmacology and function of reward pathways.

  1992cited by this paper
• Localization and quantification of pro-opiomelanocortin mRNA and glucocorticoid receptor mRNA in pituitaries of suicide victims.

  1992cited by this paper
• Increased 5-HT-2 receptor function as measured by serotonin-stimulated phosphoinositide hydrolysis in platelets of depressed patients.

  1991cited by this paper
• Autoradiographic demonstration of increased serotonin 5-HT2 and beta-adrenergic receptor binding sites in the brain of suicide victims.

  1990cited by this paper
• Pathophysiology of HPA axis abnormalities in patients with major depression: an update.

  1989cited by this paper
• Elevated CSF CRF in suicide victims.

  1989cited by this paper
• Suicide attempts in the Epidemiologic Catchment Area Study.

  1988cited by this paper
• Increased serotonin2 and beta-adrenergic receptor binding in the frontal cortices of suicide victims.

  1986cited by this paper
• Life Events, Early Loss, and Personality

  1986cited by this paper

• Sunlight and suicide risk: mediating effect of high temperature in China

  2026cites this paper
• 5-hydroxyindole acetic acid level in cerebrospinal fluid as a potential biological marker for suicide

  2025cites this paper
• LSD: Mechanisms and Relevance to the Treatment of Depression.

  2025cites this paper
• Hippocampal Zkscan4 confers resilience to chronic stress–induced depression-like behaviors

  2025cites this paper
• Cortical 5-HT2A receptors in depression and suicide: a systematic review and meta-analysis of in vivo and post-mortem imaging studies

  2025cites this paper
• Relationship between increased binding potential of possible 5-HT2A receptors in the ventral hippocampus by subchronic phencyclidine and disturbed social interaction in rats: a PET study using 18F-altanserin.

  2025cites this paper
• Clozapine's Molecular Signature: Selective 5‐HT2A Receptor Downregulation and Signalling in Rat Brain Cortical Regions

  2025cites this paper
• From trauma to depression: structural, synaptic, epigenetic, and molecular pathways linking early stress to lifelong vulnerability

  2025cites this paper
• Molecular Mechanisms of Menstrual Cycle-Related Suicide Risk: A Selective Review of Promising Candidate Systems.

  2025cites this paper
• Effect of daily temperature variations on years of life lost from suicide in the capital city of South Korea.

  2024cites this paper
• Dimethyltryptamine (DMT) and ibogaine elicit membrane effects in HEK cells transiently transfected with the human 5-HT2A receptor.

  2024cites this paper
• Autism, youth suicide, and psychedelics: A review of the 21st century evidence

  2024cites this paper
• The role of serotonin in depression—A historical roundup and future directions

  2024cites this paper
• Inflammatory mediators in major depression and bipolar disorder

  2024cites this paper
• Magnetic resonance imaging of regional gray matter volume in persons who died by suicide

  2024influential citation
• Unveiling behavioral and molecular neuroadaptations related to the antidepressant action of cannabidiol in the unpredictable chronic mild stress model

  2023cites this paper
• Unveiling the Psychedelic Journey: An Appraisal of Psilocybin as a Profound Antidepressant Therapy

  2023cites this paper
• Differential Expression of HTR2A and MAOA Genes in the Prefrontal Cortex and Hypothalamus of Suicide Victims from Mexican Population.

  2022cites this paper
• Neural Plasticity in the Ventral Tegmental Area, Aversive Motivation during Drug Withdrawal and Hallucinogenic Therapy

  2022cites this paper
• Three Naturally-Occurring Psychedelics and Their Significance in the Treatment of Mental Health Disorders

  2022cites this paper
• Suicide: Allostatic regulation and resilience.

  2022cites this paper
• Effects of stress on endophenotypes of suicide across species: A role for ketamine in risk mitigation

  2022cites this paper
• Elevated levels of serotonin 5-HT_2A receptors in the orbitofrontal cortex of antisocial individuals

  2022cites this paper
• The role of mental health and substance use disorders on the relation of migraine with self-directed violence among women in the United States.

  2022cites this paper
• Serotonin Receptor 5-HT2A Regulates TrkB Receptor Function in Heteroreceptor Complexes

  2022cites this paper
• Dysregulation of Protein Kinase C in Adult Depression and Suicide: Evidence From Postmortem Brain Studies

  2021cites this paper
• Potential lethality of suicide attempts in youth

  2021cites this paper
• Associations and interactions of the serotonin receptor genes 5-HT1A, 5-HT2A, and childhood trauma with alexithymia in two independent general-population samples.

  2021cites this paper
• Psilocybin as a Novel Pharmacotherapy for Treatment-Refractory Anorexia Nervosa

  2021cites this paper
• Classical Psychedelics as Therapeutics in Psychiatry – Current Clinical Evidence and Potential Therapeutic Mechanisms in Substance Use and Mood Disorders

  2021cites this paper
• Youth Suicide in India: A Critical Review and Implication for the National Suicide Prevention Policy

  2021cites this paper
• Hippocampal neuropathology in suicide: Gaps in our knowledge and opportunities for a breakthrough.

  2021cites this paper
• Electrophysiological correlates of suicidality.

  2021cites this paper
• Psilocybin, a Naturally Occurring Indoleamine Compound, Could Be Useful to Prevent Suicidal Behaviors

  2021cites this paper
• Rediscovering Psilocybin as an Antidepressive Treatment Strategy

  2021cites this paper
• Early Childhood Adversity, Stress, and Developmental Pathways of Suicide Risk

  2021cites this paper
• Genetics of Adolescent Suicide: A Literature review

  2021cites this paper
• Prevalence and Factors Associated With Suicidal Ideation in Medical Students With Migraine

  2021cites this paper
• Suicide prevention in childhood and adolescence: a narrative review of current knowledge on risk and protective factors and effectiveness of interventions

  2021cites this paper
• Serotonin/dopamine interaction: Electrophysiological and neurochemical evidence.

  2021cites this paper
• Overcoming Depression with 5-HT2A Receptor Ligands

  2021cites this paper
• Exploiting Circulating MicroRNAs as Biomarkers in Psychiatric Disorders

  2020cites this paper
• Gene-Based Association Analysis Suggests Association of HTR2A With Antidepressant Treatment Response in Depressed Patients

  2020cites this paper
• Pharmacodynamic Gene Testing in Prader-Willi Syndrome

  2020cites this paper
• Differential Expression of HTR2A and MAOA Genes in the Prefrontal Cortex and Hypothalamus of Suicide Victims from a Mexican Population

  2020influential citation
• The Effect of Lactobacillus casei Consumption in Improvement of Obsessive–Compulsive Disorder: an Animal Study

  2020cites this paper
• High-lethality of suicide attempts associated with platelet to lymphocyte ratio and mean platelet volume in psychiatric inpatient setting

  2020cites this paper
• Psilocybin as a New Approach to Treat Depression and Anxiety in the Context of Life-Threatening Diseases—A Systematic Review and Meta-Analysis of Clinical Trials

  2020cites this paper
• Understanding the Complex of Suicide in Depression: from Research to Clinics

  2020cites this paper
• Biomarkers of suicidal behaviors: A comprehensive critical review.

  2020cites this paper
• Calcium-binding proteins are altered in the cerebellum in schizophrenia

  2020cites this paper
• Pivotal mental states

  2020cites this paper
• Association between TNF-alpha polymorphism and the age of first suicide attempt in chronic patients with schizophrenia

  2020cites this paper
• Neurobiological understanding of suicide

  2019cites this paper
• New Psychoactive Substances (NPS), Psychedelic Experiences and Dissociation: Clinical and Clinical Pharmacological Issues

  2019cites this paper
• Serotonin 2A receptors are a stress response system: implications for post-traumatic stress disorder

  2019cites this paper
• Classical psychedelics for the treatment of depression and anxiety: A systematic review.

  2019cites this paper
• Biological bases of suicidal behaviours: A narrative review

  2019cites this paper
• Neurobiological understanding of suicide

  2019cites this paper
• Application of an intersectional framework to understanding the association of disability and sexual orientation with suicidal ideation among Oregon Teens.

  2019cites this paper
• Molecular programs underlying differences in the expression of mood disorders in males and females.

  2019cites this paper
• Adaptive mechanisms following antidepressant drugs: Focus on serotonin 5-HT_2A receptors

  2019cites this paper
• Inference of cell type content from human brain transcriptomic datasets illuminates the effects of age, manner of death, dissection, and psychiatric diagnosis

  2018cites this paper
• Safety Issues in a General Medical Facility Setting

  2018cites this paper
• Annual Research Review: Suicide among youth – epidemiology, (potential) etiology, and treatment

  2018cites this paper
• A urinary metabolomics (GC-MS) strategy to evaluate the antidepressant-like effect of chlorogenic acid in adrenocorticotropic hormone-treated rats

  2018cites this paper
• Modeling suicide in bipolar disorders

  2018cites this paper
• Serotonin receptors and suicide, major depression, alcohol use disorder and reported early life adversity

  2018cites this paper
• Psychiatric Comorbidity in Migraine and Chronic Headache

  2017cites this paper
• Invloed van langdurige vroegkinderlijke negatieve ervaringen op de ontwikkeling van de borderlinepersoonlijkheidsstoornis

  2017cites this paper
• 5-HT2A receptor deficiency alters the metabolic and transcriptional, but not the behavioral, consequences of chronic unpredictable stress

  2017cites this paper
• The Mechanism of Depression in Adolescence Has a Higher Morbidity

  2017cites this paper
• Experimental occlusal disharmony – A promoting factor for anxiety in rats under chronic psychological stress

  2017cites this paper
• Psychiatric comorbidity in new daily persistent headache: A cross‐sectional study

  2017cites this paper
• Research on potential biomarker correlates for suicidal behavior: A review

  2017cites this paper
• ERβ and ApoE isoforms interact to regulate BDNF–5-HT2A signaling and synaptic function in the female brain

  2017cites this paper
• Serotonin and brain function: a tale of two receptors

  2017cites this paper
• The Life Span Model of Suicide and Its Neurobiological Foundation

  2017cites this paper
• The fibrinolytic system: A new target for treatment of depression with psychedelics.

  2017cites this paper
• A Novel Role of Serotonin Receptor 2B Agonist as an Anti-Melanogenesis Agent

  2016cites this paper
• Subchronic and mild social defeat stress alter mouse nest building behavior.

  2016cites this paper
• Psychedelics

  2016cites this paper
• Psilocybin for depression and anxiety associated with life-threatening illnesses

  2016cites this paper
• Structural and Neurochemical Alterations in Brain Regions of Depression and Suicide Patients

  2016cites this paper
• Inference of Cell Type Composition from Human Brain Transcriptomic Datasets Illuminates the Effects of Age, Manner of Death, Dissection, and Psychiatric Diagnosis

  2016cites this paper
• REGION-SPECIFIC REGULATION OF THE SEROTONIN 2 A RECEPTOR EXPRESSION IN DEVELOPMENT AND AGING IN POSTMORTEM HUMAN BRAIN

  2016cites this paper
• Neurobiology and Pharmacological Prevention of Suicide in Mood Disorders

  2016cites this paper
• SUICIDIO Y TRASTORNO MENTAL (Suicide and Mental Disorder)

  2016cites this paper
• Depression in Children and Adolescents

  2016cites this paper
• Rapid and sustained symptom reduction following psilocybin treatment for anxiety and depression in patients with life-threatening cancer: a randomized controlled trial

  2016cites this paper
• Neurobiología de la depresión mayor y de su tratamiento farmacológico

  2016cites this paper
• Neuropeptide Y administration reverses tricyclic antidepressant treatment-resistant depression induced by ACTH in mice.

  2015cites this paper
• Targets Associated with Drug‐Related Suicidal Ideation and Behavior

  2015cites this paper
• Region‐specific regulation of the serotonin 2A receptor expression in development and ageing in post mortem human brain

  2015cites this paper
• Correlation between Bipolar Affective Disorder and Suicide Reviewing by the Risk Factors: a Systematic Review

  2015cites this paper
• 4 – Approches pharmacologique et physiopathologique de la dépression majeure : un aller-retour paradigmatique

  2015cites this paper
• Brain Invaders: Exploring the Impact of Platelet Transmigration on Serotonin Signaling in the Medial Prefrontal Cortex

  2015cites this paper
• Central serotonin-2A (5-HT2A) receptor dysfunction in depression and epilepsy: the missing link?

  2015cites this paper
• Relationship between Serotonergic Dysfunction Based on Loudness Dependence of Auditory-Evoked Potentials and Suicide in Patients with Major Depressive Disorder

  2015cites this paper
• Associations between climate variability, unemployment and suicide in Australia: a multicity study

  2015cites this paper