Comparison of antisense oligonucleotides and siRNAs in cell culture and in vivo.

No abstract is available for this paper.

• Publication year

  2002

• Venue

  Biochemical and Biophysical Research Communications - BBRC

• Publication date

  2002-08-30

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/S0006-291X(02)02013-2PMID 12200148
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Novel antisense and peptide nucleic acid strategies for controlling gene expression.

  2002cited by this paper
• Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

  2001cited by this paper
• Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems

  2001cited by this paper
• Molecular Cloning: A Laboratory Manual

  2001cited by this paper
• An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells

  2000cited by this paper
• EWS fli-1 antisense nanocapsules inhibits ewing sarcoma-related tumor in mice.

  2000cited by this paper
• Physico-chemical and biological properties of antisense phosphodiester oligonucleotides with various secondary structures.

  1999cited by this paper
• Cell cycle-dependent distribution and specific inhibitory effect of vectorized antisense oligonucleotides in cell culture.

  1999cited by this paper
• A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding.

  1976cited by this paper
• Nonlinear limits to the information capacity of optical ® bre communications

  year unknowncited by this paper

• Harnessing State-of-the-Art Gene Therapy to Transform Oral Cancer Treatment

  2025cites this paper
• Research hotspots and trends of immunotherapy and melanoma: A bibliometric analysis during 2014–2024

  2025cites this paper
• Multiplexed In Vivo Screening Using Barcoded Aptamer Technology to Identify Oligonucleotide-Based Targeting Reagents

  2024cites this paper
• Small Interfering RNA Drug Delivery System in Cancer

  2024influential citation
• Recent Progress of Small Interfering RNA Delivery on the Market and Clinical Stage.

  2024cites this paper
• Targeted therapy, immunotherapy, and small molecules and peptidomimetics as emerging immunoregulatory agents for melanoma.

  2024cites this paper
• Gene therapy as a treatment of oral cancer: An insight

  2023cites this paper
• Preparation and stability of pegylated poly(S-alkyl-L-homocysteine) coacervate core micelles in aqueous media

  2023cites this paper
• Induction of osteogenic differentiation of MSCs by GSK3β knockdown through GSK3β siRNAs transfection

  2023cites this paper
• Antisense Oligonucleotide Therapy for the Nervous System: From Bench to Bedside with Emphasis on Pediatric Neurology

  2022cites this paper
• Therapeutic silencing of mTOR by systemically administered siRNA-loaded neutral liposomal nanoparticles inhibits DMBA-induced mammary carcinogenesis

  2022cites this paper
• Treatment of the metabolic syndrome by siRNA targeting apolipoprotein CIII

  2022cites this paper
• Novel antihypertensive agents for resistant hypertension: what does the future hold?

  2022influential citation
• Future Developments in the Treatment of AL Amyloidosis

  2022cites this paper
• Liposomes, new carriers for delivery of genes and anticancer drugs: a systematic review

  2021cites this paper
• Rabies Prophylactic and Treatment Options: An In Vitro Study of siRNA- and Aptamer-Based Therapeutics

  2021cites this paper
• Systematic Combination of Oligonucleotides and Synthetic Polymers for Advanced Therapeutic Applications

  2021cites this paper
• Non-Cationic RGD-Containing Protein Nanocarrier for Tumor-Targeted siRNA Delivery

  2021cites this paper
• Gene Therapy in Oncology

  2020cites this paper
• Pulmonary Administration: Strengthening the Value of Therapeutic Proximity

  2020cites this paper
• Intranasal administration of regulatory dendritic cells is useful for the induction of nasal mucosal tolerance in a mice model of allergic rhinitis

  2020cites this paper
• Synthesis and Evaluation of Neutral Phosphate Triester Backbone-Modified siRNAs.

  2020cites this paper
• DNA complexes as an efficient gene anticancer drug delivery therapy

  2019cites this paper
• Prevalence and risk factors of allergic rhinitis in children in Bangkok area.

  2019cites this paper
• RNA Interference Technology

  2019cites this paper
• Targeting angiotensinogen with RNA-based therapeutics.

  2019cites this paper
• Prevalence and severity of asthma, rhinoconjunctivitis and eczema in children from the Bangkok area: The Global Asthma Network (GAN) Phase I.

  2019cites this paper
• Title: Targeting islet PTP1B improves islet graft revascularization and transplant outcomes

  2019cites this paper
• eIF4E is a critical regulator of human papillomavirus (HPV)-immortalized cervical epithelial (H8) cell growth induced by nicotine.

  2019cites this paper
• Designing siRNA-conjugated plant oil-based nanoparticles for gene silencing and cancer therapy

  2019cites this paper
• Nanomaterials-Based siRNA Delivery: Routes of Administration, Hurdles and Role of Nanocarriers

  2019cites this paper
• Formulation of a therapeutic cationic liposome-siRNA complex for development to fight osteosarcoma

  2019cites this paper
• Polymorphisms in the interleukin 4 receptor and interleukin 13 genes in immediate allergic reactions to beta-lactam antibiotics: A case-control study.

  2019cites this paper
• Nanotechnology in Modern Animal Biotechnology

  2019cites this paper
• A novel allergen-specific therapy with regulatory T cells induced by CD40-silenced dendritic cells.

  2019cites this paper
• Targeting pancreatic islet PTP1B improves islet graft revascularization and transplant outcomes

  2019cites this paper
• Prevalence of allergic rhinitis comorbidity with asthma and asthma with allergic rhinitis in China: A meta-analysis.

  2019cites this paper
• Molecular plant physiology

  2019cites this paper
• Preparation of PEGylated cationic nanoliposome-siRNA complexes for cancer therapy

  2018cites this paper
• siRNA: A Promising New Tool for Future Breast Cancer Therapy

  2018cites this paper
• Fluorescent nanodiamonds as siRNA vectors : in vitro efficacy evaluation and high-content/high-resolution quantifications of their distribution in vivo. (Nanodiamants fluorescents pour la vectorisation de siRNA : évaluation in vitro et quantifications haut-débit/haute-résolution in vivo)

  2018cites this paper
• Synergic Effects of CD40 and CD86 Silencing in Dendritic Cells on the Control of Allergic Diseases

  2018cites this paper
• Nanoparticle-Patterned Multicompartmental Chitosan Capsules for Oral Delivery of Oligonucleotides.

  2018cites this paper
• Recent Advances in RNA Therapeutics and RNA Delivery Systems Based on Nanoparticles

  2018cites this paper
• Optimization of siRNA delivery to target sites: issues and future directions

  2018cites this paper
• Development of Polymeric Carriers for the Treatment of Acute Kidney Injury

  2018cites this paper
• Therapeutic Potency of Nanoformulations of siRNAs and shRNAs in Animal Models of Cancers

  2018cites this paper
• Investigation into the role of the long non-coding RNAs NEAT1 and MIAT in breast cancer

  2018cites this paper
• Evaluating the Mechanisms of Light-Triggered siRNA Release from Nanoshells for Temporal Control Over Gene Regulation.

  2018cites this paper
• Cytosolic delivery of siRNA by ultra-high affinity dsRNA binding proteins

  2017cites this paper
• Selective α-Synuclein Knockdown in Monoamine Neurons by Intranasal Oligonucleotide Delivery: Potential Therapy for Parkinson's Disease.

  2017cites this paper
• Engineering of small interfering RNA‐loaded lipidoid‐poly(DL‐lactic‐co‐glycolic acid) hybrid nanoparticles for highly efficient and safe gene silencing: A quality by design‐based approach

  2017cites this paper
• Delivering siRNA with Dendrimers: In Vivo Applications.

  2017cites this paper
• Polymers in the Co-delivery of siRNA and Anticancer Drugs for the Treatment of Drug-resistant Cancers

  2017cites this paper
• siRNA-based nucleoceuticals for tissue regeneration

  2017cites this paper
• Exosome-based small RNA delivery: Progress and prospects

  2017cites this paper
• Polymeric nanoparticles of siRNA prepared by a double-emulsion solvent-diffusion technique: Physicochemical properties, toxicity, biodistribution and efficacy in a mammary carcinoma mice model.

  2017cites this paper
• Survivin downregulation using siRNA nanoliposomes inhibits cell proliferation and promotes the apoptosis of MHCC-97H hepatic cancer cells: An in vitro and in vivo study

  2017cites this paper
• PTTG, PBF and P53 in head and neck cancer

  2017cites this paper
• Prospects of siRNA applications in regenerative medicine.

  2017cites this paper
• Harnessing CRISPR/Cas systems for programmable transcriptional and post-transcriptional regulation.

  2017cites this paper
• Safety of antisense oligonucleotide and siRNA-based therapeutics.

  2017cites this paper
• Omics‐Based Nanopharmacy: Powerful Tools Toward Precision Medicine

  2016cites this paper
• Inhibitory Effect of TLR4 Gene Silencing on Intimal Hyperplasia of Vein Grafting

  2016cites this paper
• The Application of Clinical Lithotripter Shock Waves to RNA Nucleotide Delivery to Cells.

  2016cites this paper
• RNAi Therapeutic Potentials and Prospects in CNS Disease

  2016cites this paper
• Short Interfering RNA Inhibits Rift Valley Fever Virus Replication and Degradation of Protein Kinase R in Human Cells

  2016cites this paper
• Delivery of RNAi Therapeutics to the Airways—From Bench to Bedside

  2016cites this paper
• Efficient Gene Suppression in Dorsal Root Ganglia and Spinal Cord Using Adeno-Associated Virus Vectors Encoding Short-Hairpin RNA.

  2016cites this paper
• RNAi agents as chikungunya virus therapeutics

  2016cites this paper
• Chemical modification of nucleic acids as a key technology for the development of RNA-based therapeutics.

  2016cites this paper
• Gene Therapy in the Management of Head and Neck Cancers: A Review. -

  2016cites this paper
• MMP13 and ISG15 are potential driver genes in oral squamous cell carcinoma / Vincent Chong Vui King

  2016cites this paper
• Synthesis and in vitro assessment of chemically modified siRNAs targeting BCL2 that contain 2′-ribose and triazole-linked backbone modifications

  2015cites this paper
• Delivering a disease-modifying treatment for Huntington's disease.

  2015cites this paper
• Gene Therapy in the Treatment and Prevention of Oral Cancer: An Overview

  2015cites this paper
• Nanocarriers for delivery of siRNA and co-delivery of siRNA and other therapeutic agents.

  2015cites this paper
• Short-interference RNAs: becoming medicines

  2015cites this paper
• Technologies for controlled, local delivery of siRNA.

  2015cites this paper
• Nanoparticle-Based Targeted Therapeutics in Head-And-Neck Cancer

  2015influential citation
• Antisense- and siRNA-mediated inhibition of the anti-apoptotic gene Bcl-xL for chemosensitization of bladder cancer cells.

  2015cites this paper
• Biocompatible and colloidally stabilized mPEG-PE/calcium phosphate hybrid nanoparticles loaded with siRNAs targeting tumors

  2015cites this paper
• RNA Interference Therapeutics – Past, Present and Future

  2015cites this paper
• Knockdown of c-Myc inhibits cell proliferation by negatively regulating the Cdk/Rb/E2F pathway in nasopharyngeal carcinoma cells.

  2015cites this paper
• Original article: SHORT-INTERFERENCE RNAS: BECOMING MEDICINES

  2015cites this paper
• Host-virus interactions in the Pacific white shrimp, Litopenaeus vannamei

  2014cites this paper
• Development of a Novel Strategy for Targeted Delivery of siRNA to B lymphocytes

  2014cites this paper
• Photo-regulation of constitutive gene expression in living cells by using ultrafast photo-cross-linking oligonucleotides.

  2014cites this paper
• RNA interference-based therapeutics: molecular platforms for infectious diseases.

  2014cites this paper
• Using Chemical Modification to Enhance siRNA Performance

  2014cites this paper
• RNAi to Treat Chronic Hepatitis C Infection

  2014cites this paper
• BRAF inhibitor therapy for melanoma, thyroid and colorectal cancers: development of resistance and future prospects.

  2014cites this paper
• Composite Colloidal Nanosystems for Targeted Delivery and Sensing1

  2014cites this paper
• Structure oligonucléotidique améliorée de type nanoparticule présentant une efficacité élevée et son procédé de préparation

  2014cites this paper
• Omics-based nanomedicine: the future of personalized oncology.

  2014cites this paper
• 호흡기 질환 연관 유전자 특이적 siRNA, 그러한 siRNA를 포함하는 이중나선 올리고 RNA 구조체 및 이를 포함하는 호흡기 질환 예방 또는 치료용 조성물

  2014cites this paper
• An overview of gene therapy in head and neck cancer

  2013cites this paper
• Dendrimers for siRNA Delivery

  2013cites this paper
• Silenciament gènic de CD40 en al•lo i autoimmunitat. Estudi de la resposta immuno inflamatòria en models animals

  2013cites this paper
• Suppression of STAT5A and STAT5B chronic myeloid leukemia cells via siRNA and antisense-oligonucleotide applications with the induction of apoptosis.

  2013cites this paper