Membrane interaction and conformational properties of the putative fusion peptide of PH-30, a protein active in sperm-egg fusion.

No abstract is available for this paper.

• Publication year

  1994

• Venue

  Biochemistry

• Publication date

  1994-04-19

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1021/BI00181A002PMID 8161498
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Solid phase peptide synthesis utilizing 9-fluorenylmethoxycarbonyl amino acids.

  2009cited by this paper
• Virus Entry into Animal Cells

  2008cited by this paper
• Mechanisms of membrane fusion.

  1993cited by this paper
• Structural elements of human parathyroid hormone and their possible relation to biological activities.

  1992cited by this paper
• Membrane fusion.

  1992cited by this paper
• Are fusion peptides really "sided" insertional helices?

  1992cited by this paper
• A potential fusion peptide and an integrin ligand domain in a protein active in sperm–egg fusion

  1992cited by this paper
• Are fusion peptides really "sided" insertional helices?

  1992cited by this paper
• Membrane destabilization by N-terminal peptides of viral envelope proteins

  1992cited by this paper
• Peptide models for the membrane destabilizing actions of viral fusion proteins

  1992cited by this paper
• Theoretical and functional analysis of the SIV fusion peptide.

  1991cited by this paper
• Membrane fusion activity of the influenza virus hemagglutinin: interaction of HA2 N-terminal peptides with phospholipid vesicles.

  1991cited by this paper
• Effects of the 'fusion peptide' from measles virus on the structure of N-methyl dioleoylphosphatidylethanolamine membranes and their fusion with Sendai virus.

  1991cited by this paper
• Orientation into the lipid bilayer of an asymmetric amphipathic helical peptide located at the N-terminus of viral fusion proteins.

  1990cited by this paper
• Proteolytic processing of a protein involved in sperm-egg fusion correlates with acquisition of fertilization competence

  1990cited by this paper
• Phospholipid interactions of synthetic peptides representing the N-terminus of HIV gp41.

  1990cited by this paper
• Hydrophobic binding of the ectodomain of influenza hemagglutinin to membranes occurs through the "fusion peptide".

  1989cited by this paper
• Identification of the fusion peptide of primate immunodeficiency viruses.

  1989cited by this paper
• New coupling reagents in peptide chemistry

  1989cited by this paper
• Membrane fusion by peptide analogues of influenza virus haemagglutinin.

  1988cited by this paper
• New insight into protein secondary structure from resolution-enhanced infrared spectra.

  1988cited by this paper
• Membrane penetration of Sendai virus glycoproteins during the early stages of fusion with liposomes as determined by hydrophobic photoaffinity labeling.

  1988cited by this paper
• Membrane binding and conformational properties of peptides representing the NH2 terminus of influenza HA-2.

  1987cited by this paper
• Solid-phase synthesis of protected peptide fragments using a trialkoxy-diphenyl-methylester resin.

  1987cited by this paper
• pH-dependent membrane fusion activity of a synthetic twenty amino acid peptide with the same sequence as that of the hydrophobic segment of influenza virus hemagglutinin.

  1987cited by this paper
• Lipid mixing during membrane aggregation and fusion: why fusion assays disagree.

  1987cited by this paper
• Calculation of protein conformation from circular dichroism.

  1986cited by this paper
• Studies on the mechanism of membrane fusion: site-specific mutagenesis of the hemagglutinin of influenza virus

  1986cited by this paper
• Conformations of signal peptides induced by lipids suggest initial steps in protein export.

  1986cited by this paper
• Production of large unilamellar vesicles by a rapid extrusion procedure: characterization of size distribution, trapped volume and ability to maintain a membrane potential.

  1985cited by this paper
• Aliphatic aldehydes promote myelin basic protein-induced fusion of phospholipid vesicles.

  1985cited by this paper
• Role of peptide structure in lipid-peptide interactions: a fluorescence study of the binding of pentagastrin-related pentapeptides to phospholipid vesicles.

  1984cited by this paper
• Use of resonance energy transfer to monitor membrane fusion.

  1981cited by this paper
• The behavior of oxonol dyes in phospholipid dispersions.

  1979cited by this paper

• The Biology of Fertilization

  2018cites this paper
• The hallmarks of cell-cell fusion

  2017cites this paper
• Endosomal escape: a bottleneck in intracellular delivery.

  2014cites this paper
• Structural properties of gp41 fusion peptide at a model membrane interface.

  2013cites this paper
• Testicular and epididymal ADAMs: expression and function during fertilization

  2012cites this paper
• Membrane interaction of synthetic peptides related to the putative fusogenic region of PH-30 alpha, a protein in sperm-egg fusion.

  2009cites this paper
• Humanes ADAM15 als potentieller natürlicher Integrin alphavbeta3-Antagonist: Einfluß der ADAM15-Expression auf Migration und Zell/Zell-Adhäsion von humanen Ovarialkarzinomzellen

  2009cites this paper
• Molecular mechanisms of sperm–egg interactions and egg activation

  2009cites this paper
• Interaction of lipophilic peptides derived from mastoparan with phospholipid vesicles.

  2009cites this paper
• ADAM function in embryogenesis.

  2009cites this paper
• Secondary structure and distribution of fusogenic LV-peptides in lipid membranes

  2008cites this paper
• Effect of pH-variation on insertion and ion channel formation of human calcitonin into planar lipid bilayers.

  2006cites this paper
• The transmembrane homotrimer of ADAM 1 in model lipid bilayers

  2006cites this paper
• Mammalian ADAMs with Testis-Specific or -Predominant Expression

  2005cites this paper
• Cross bridging proteins in nature and their utilization in bio- and nanotechnology.

  2004cites this paper
• Effect of nanomolar concentrations of sodium dodecyl sulfate, a catalytic inductor of alpha-helices, on human calcitonin incorporation and channel formation in planar lipid membranes.

  2004cites this paper
• Biochemical and Molecular Characterization of Bovine Fertilin a and (ADAM 1 and ADAM 2): A Candidate Sperm-Egg Binding/Fusion Complex'

  2004cites this paper
• A soluble peripherin/Rds C-terminal polypeptide promotes membrane fusion and changes conformation upon membrane association.

  2003cites this paper
• Platelet-derived Growth Factor (PDGF)-C, a PDGF Family Member with a Vascular Endothelial Growth Factor-like Structure*

  2003cites this paper
• Identification of the 48-kDa G11 protein from guinea pig testes as sperad.

  2002cites this paper
• Membrane-active properties of alpha-MSH analogs: aggregation and fusion of liposomes triggered by surface-conjugated peptides.

  2002cites this paper
• Monoclonal antibody G3 epitope location on Guinea pig sperm membrane protein, sperad.

  2002cites this paper
• Fusion of Biological Membranes and Related Problems

  2002cites this paper
• Interaction with membranes of peptides related to the fusogenic region of PH-30α, a sperm-egg fusion protein

  2002cites this paper
• Immunolocalization of a guinea pig sperm surface antigen recognized by a monoclonal antibody E74.

  2002cites this paper
• Molecular mechanisms involved in mammalian gamete fusion.

  2001cites this paper
• Involvement of ADAM9 in multinucleated giant cell formation of blood monocytes.

  2001cites this paper
• A profile of fertilization in mammals

  2001cites this paper
• Endogenous meltrin alpha is ubiquitously expressed and associated with the plasma membrane but exogenous meltrin alpha is retained in the endoplasmic reticulum.

  2000cites this paper
• Mutational Analysis of the Subgroup A Avian Sarcoma and Leukosis Virus Putative Fusion Peptide Domain

  2000cites this paper
• Analysis of mouse fertilin in wild-type and fertilin beta(-/-) sperm: evidence for C-terminal modification, alpha/beta dimerization, and lack of essential role of fertilin alpha in sperm-egg fusion.

  2000cites this paper
• Common Properties of Fusion Peptides from Diverse Systems

  2000cites this paper
• DEPLOYMENT OF MEMBRANE FUSION PROTEIN DOMAINS DURING FUSION

  2000cites this paper
• Experimental approaches for the structural characterization of membrane-spanning segments in proteins

  2000cites this paper
• Dynamics of the mammalian sperm plasma membrane in the process of fertilization.

  2000cites this paper
• The Central Proline of an Internal Viral Fusion Peptide Serves Two Important Roles

  2000cites this paper
• Current status of pH-sensitive liposomes in drug delivery.

  2000cites this paper
• A peptide analogue to a fusion domain within photoreceptor peripherin/rds promotes membrane adhesion and depolarization.

  2000cites this paper
• Analysis of Mouse Fertilin in Wild-Type and Fertilin β−/− Sperm: Evidence for C-terminal Modification, α/β Dimerization, and Lack of Essential Role of Fertilin α in Sperm–Egg Fusion

  2000cites this paper
• Integrins: Regulators of embryogenesis

  2000cites this paper
• Integrins and disintegrins: the candidate molecular players in sperm-egg interaction.

  2000cites this paper
• Specific roles for lipids in virus fusion and exit. Examples from the alphaviruses.

  2000cites this paper
• Mammalian fertilization: molecular aspects of gamete adhesion, exocytosis, and fusion.

  1999cites this paper
• Peptides and Membrane Fusion: Towards an Understanding of the Molecular Mechanism of Protein-Induced Fusion

  1999cites this paper
• Proteases New Perspectives

  1999cites this paper
• Role of the N-terminal peptides of viral envelope proteins in membrane fusion.

  1999cites this paper
• Are the fusion processes involved in birth, life and death of the cell depending on tilted insertion of peptides into membranes?

  1999cites this paper
• Membrane interactions of the putative fusion peptide (MF alpha P) from fertilin-alpha, the mouse sperm protein complex involved in fertilization.

  1999cites this paper
• Membrane fusion induced by a short fusogenic peptide is assessed by its insertion and orientation into target bilayers.

  1999cites this paper
• Sperm disintegrins, egg integrins, and other cell adhesion molecules of mammalian gamete plasma membrane interactions.

  1999cites this paper
• Cell-associated metalloproteinases

  1999cites this paper
• Ultrastructural characterization of peptide-induced membrane fusion and peptide self-assembly in the lipid bilayer.

  1999cites this paper
• Contribution of the hydrophobicity gradient to the secondary structure and activity of fusogenic peptides.

  1999cites this paper
• Macaque MDC family of proteins: sequence analysis, tissue distribution and processing in the male reproductive tract.

  1998cites this paper
• Molecules involved in mammalian sperm-egg interaction.

  1998cites this paper
• ADAM 20 and 21; two novel human testis-specific membrane metalloproteases with similarity to fertilin-α

  1998cites this paper
• Structural properties of the putative fusion peptide of fertilin, a protein active in sperm-egg fusion, upon interaction with the lipid bilayer.

  1998cites this paper
• Application of membrane-active peptides for drug and gene delivery across cellular membranes.

  1998cites this paper
• Membrane fusion induced by 11-mer anionic and cationic peptides: a structure-function study.

  1998cites this paper
• ADAM 20 and 21; two novel human testis-specific membrane metalloproteases with similarity to fertilin-alpha.

  1998cites this paper
• Characterisation of two highly conserved but non-allelic cellular disintegrins from rabbit testis.

  1998cites this paper
• Enhanced efficiency of a targeted fusogenic peptide.

  1998cites this paper
• Membrane Fusion Is Induced by a Distinct Peptide Sequence of the Sea Urchin Fertilization Protein Bindin*

  1998cites this paper
• Destabilization and fusion of zwitterionic large unilamellar lipid vesicles induced by a beta-type structure of the HIV-1 fusion peptide

  1998cites this paper
• Roles in Cell-to-Cell Fusion of Two Conserved Hydrophobic Regions in the Murine Coronavirus Spike Protein

  1998cites this paper
• Molecular basis of sperm-egg interaction and the prospects for immunocontraception.

  1998cites this paper
• Fusion between retinal rod outer segment membranes and model membranes: a role for photoreceptor peripherin/rds.

  1998cites this paper
• Structural plasticity of the feline leukaemia virus fusion peptide: a circular dichroism study

  1998cites this paper
• Chapter 6 Modulation of Lipid Polymorphism by Peptides

  1997cites this paper
• Biochemical and molecular characterization of bovine fertilin alpha and beta (ADAM 1 and ADAM 2): a candidate sperm-egg binding/fusion complex.

  1997cites this paper
• Why did the sperm cross the cumulus? To get to the oocyte. Functions of the sperm surface proteins PH-20 and fertilin in arriving at, and fusing with, the egg.

  1997cites this paper
• Comparison of lipid vesicle fusion induced by the putative fusion peptide of fertilin (a protein active in sperm‐egg fusion) and the NH2‐terminal domain of the HIV2 gp41

  1997cites this paper
• Permeabilization and fusion of uncharged lipid vesicles induced by the HIV-1 fusion peptide adopting an extended conformation: dose and sequence effects.

  1997cites this paper
• The mammalian acrosome reaction: Gateway to sperm fusion with the oocyte?

  1997cites this paper
• Characterization and isolation of SOB2, a human sperm protein with a potential role in oocyte membrane binding.

  1997cites this paper
• Examination of the immunocontraceptive potential of recombinant rabbit fertilin subunits in rabbit.

  1997cites this paper
• Infrared spectroscopy of proteins and peptides in lipid bilayers

  1997cites this paper
• Characterization of the binding of recombinant mouse sperm fertilin alpha subunit to mouse eggs: evidence for function as a cell adhesion molecule in sperm-egg binding.

  1997cites this paper
• Rotavirus contains integrin ligand sequences and a disintegrin-like domain that are implicated in virus entry into cells.

  1997cites this paper
• A model for sperm-egg binding and fusion based on ADAMs and integrins.

  1997cites this paper
• Protein involvement in the fusion between the equatorial segment of acrosome-reacted human spermatozoa and liposomes.

  1997cites this paper
• Snake Venom Disintegrins and Disintegrin-Like Domains: Soluble Antagonists and Cellular Ligands of Integrin Receptors

  1997cites this paper
• Structural properties of the putative fusion peptide of hepatitis B virus upon interaction with phospholipids. Circular dichroism and Fourier-transform infrared spectroscopy studies.

  1996cites this paper
• Cloning and expression of recombinant rabbit fertilin

  1996cites this paper
• Alpha-helical, but not beta-sheet, propensity of proline is determined by peptide environment.

  1996cites this paper
• The molecules of mammalian fertilization.

  1996cites this paper
• Egg Membranes during Fertilization

  1996cites this paper
• Bilayer-Peptide Interactions

  1996cites this paper
• Fusogenic Properties of the C-terminal Domain of the Alzheimer β-Amyloid Peptide*

  1996cites this paper
• ADAMs in fertilization and development.

  1996cites this paper
• Virus-cell and cell-cell fusion.

  1996cites this paper
• Initial evaluation of fertilin as an immunocontraceptive antigen and molecular cloning of the cynomolgus monkey fertilin β subunit

  1996cites this paper
• Effect of the N-terminal glycine on the secondary structure, orientation, and interaction of the influenza hemagglutinin fusion peptide with lipid bilayers.

  1996cites this paper
• Adhesion molecules in human sperm-oocyte interaction: relevance to infertility.

  1996influential citation
• ADAMs and cell fusion.

  1996cites this paper
• [ADAM family proteins and cell fusion].

  1996cites this paper
• Integrins and human reproduction.

  1996cites this paper
• Conformational analysis of bioactive peptides in reverse micelles as mimics of cell membrane environments

  1995cites this paper
• Monoclonal antibodies which recognize equatorial segment epitopes presented de novo following the A23187-induced acrosome reaction of guinea pig sperm.

  1995cites this paper
• ADAM, a widely distributed and developmentally regulated gene family encoding membrane proteins with a disintegrin and metalloprotease domain.

  1995cites this paper