Store‐operated calcium entry is required for sustained contraction and Ca2+ oscillations of airway smooth muscle

No abstract is available for this paper.

• Publication year

  2017

• Venue

  Journal of Physiology

• Publication date

  2017-05-15

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1113/JP272694PMID 27396568PMCID PMC5430234
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Loss of β-adrenergic–stimulated phosphorylation of CaV1.2 channels on Ser1700 leads to heart failure

  2016cited by this paper
• Phosphorylation of Cav1.2 on S1928 uncouples the L‐type Ca2+ channel from the β2 adrenergic receptor

  2016cited by this paper
• The Cav1.2 N terminus contains a CaM kinase site that modulates channel trafficking and function

  2015cited by this paper
• Principles and standards for reporting animal experiments in The Journal of Physiology and Experimental Physiology

  2015cited by this paper
• Ryanodine receptor sensitization results in abnormal calcium signaling in airway smooth muscle cells.

  2015cited by this paper
• Pharmacological targeting of AKAP-directed compartmentalized cAMP signalling.

  2015cited by this paper
• Mechanisms of Cigarette Smoke Effects on Human Airway Smooth Muscle

  2015influential reference
• Role of the store‐operated calcium entry protein, STIM1, in neutrophil chemotaxis and infiltration into a murine model of psoriasis‐inflamed skin

  2015influential reference
• A Quantitative Model of the GIRK1/2 Channel Reveals That Its Basal and Evoked Activities Are Controlled by Unequal Stoichiometry of Gα and Gβγ

  2015cited by this paper
• Apparent lack of physical or functional interaction between CaV1.1 and its distal C terminus

  2015cited by this paper
• Evolving Concepts of Asthma.

  2015influential reference
• The Role of Auxiliary Subunits for the Functional Diversity of Voltage-Gated Calcium Channels

  2015cited by this paper
• Store-Operated Calcium Channels.

  2015cited by this paper
• Novel approaches to examine the regulation of voltage-gated calcium channels in the heart.

  2015cited by this paper
• Recruitment of Gβγ controls the basal activity of G‐protein coupled inwardly rectifying potassium (GIRK) channels: crucial role of distal C terminus of GIRK1

  2014cited by this paper
• Bitter tasting compounds dilate airways by inhibiting airway smooth muscle calcium oscillations and calcium sensitivity

  2014cited by this paper
• Differential regulation of CaV1.2 channels by cAMP-dependent protein kinase bound to A-kinase anchoring proteins 15 and 79/150

  2014cited by this paper
• Inflammation, caveolae and CD38-mediated calcium regulation in human airway smooth muscle.

  2014cited by this paper
• Key Role for Store-Operated Ca2+ Channels in Activating Gene Expression in Human Airway Bronchial Epithelial Cells

  2014cited by this paper
• Calcium signaling in B cells: regulation of cytosolic Ca2+ increase and its sensor molecules, STIM1 and STIM2.

  2014influential reference
• L-type CaV1.2 calcium channels: from in vitro findings to in vivo function.

  2014cited by this paper
• The autonomic nervous system and heart failure.

  2014cited by this paper
• A new phosphorylation site in cardiac L-type Ca2+ channels (Cav1.2) responsible for its cAMP-mediated modulation.

  2014cited by this paper
• Basal and β-adrenergic regulation of the cardiac calcium channel CaV1.2 requires phosphorylation of serine 1700

  2014cited by this paper
• The cardiac L-type calcium channel distal carboxy terminus autoinhibition is regulated by calcium.

  2013cited by this paper
• &bgr;-Adrenergic Regulation of the L-type Ca2+ Channel Does Not Require Phosphorylation of &agr;1C Ser1700

  2013cited by this paper
• Competitive and Non-competitive Regulation of Calcium-dependent Inactivation in CaV1.2 L-type Ca2+ Channels by Calmodulin and Ca2+-binding Protein 1*

  2013cited by this paper
• Sarcoplasmic reticulum Ca(2+) refilling is determined by L-type Ca(2+) and store operated Ca(2+) channels in guinea pig airway smooth muscle.

  2013cited by this paper
• Molecular pharmacology of store-operated CRAC channels

  2013cited by this paper
• Characterization of selective Calcium-Release Activated Calcium channel blockers in mast cells and T-cells from human, rat, mouse and guinea-pig preparations.

  2013cited by this paper
• Activation of Store-Operated Calcium Entry in Airway Smooth Muscle Cells: Insight from a Mathematical Model

  2013cited by this paper
• The action of selective CRAC channel blockers is affected by the Orai pore geometry

  2013influential reference
• Regulation of cardiac L-type Ca²⁺ channel CaV1.2 via the β-adrenergic-cAMP-protein kinase A pathway: old dogmas, advances, and new uncertainties.

  2013cited by this paper
• Muscarinic receptors on airway mesenchymal cells: novel findings for an ancient target.

  2013cited by this paper
• Phosphorylation sites required for regulation of cardiac calcium channels in the fight-or-flight response

  2013cited by this paper
• Caveolin-1 regulation of store-operated Ca2+ influx in human airway smooth muscle

  2012cited by this paper
• Calcium channel auxiliary α2δ and β subunits: trafficking and one step beyond

  2012cited by this paper
• Modulation of distinct isoforms of L-type calcium channels by G(q)-coupled receptors in Xenopus oocytes: antagonistic effects of Gβγ and protein kinase C.

  2012cited by this paper
• Assembly of allosteric macromolecular switches: lessons from PKA

  2012cited by this paper
• A‐kinase anchoring proteins as potential drug targets

  2012cited by this paper
• CRACM/Orai ion channel expression and function in human lung mast cells

  2012cited by this paper
• STIM proteins: dynamic calcium signal transducers

  2012influential reference
• Cardiomyocytes from AKAP7 knockout mice respond normally to adrenergic stimulation

  2012cited by this paper
• Ahnak1 interaction is affected by phosphorylation of Ser-296 on Cavβ₂.

  2012cited by this paper
• Deletion of the C-terminal Phosphorylation Sites in the Cardiac β-Subunit Does Not Affect the Basic β-Adrenergic Response of the Heart and the Cav1.2 Channel*

  2012cited by this paper
• Truncation of Murine Cav1.2 at Asp-1904 Results in Heart Failure after Birth*

  2011cited by this paper
• Nanomolar potency and selectivity of a Ca2+ release-activated Ca2+ channel inhibitor against store-operated Ca2+ entry and migration of vascular smooth muscle cells

  2011cited by this paper
• Deletion of the Distal C Terminus of CaV1.2 Channels Leads to Loss of β-Adrenergic Regulation and Heart Failure in Vivo*

  2011cited by this paper
• Molecular Mechanism of Calcium Channel Regulation in the Fight-or-Flight Response

  2010cited by this paper
• Sympathetic Stimulation of Adult Cardiomyocytes Requires Association of AKAP5 With a Subpopulation of L-Type Calcium Channels

  2010cited by this paper
• Reverse mode Na+/Ca2+ exchange mediated by STIM1 contributes to Ca2+ influx in airway smooth muscle following agonist stimulation

  2010cited by this paper
• Cyclic AMP- and (Rp)-cAMPS-induced Conformational Changes in a Complex of the Catalytic and Regulatory (RIα) Subunits of Cyclic AMP-dependent Protein Kinase*

  2010cited by this paper
• Regulation of basal and reserve cardiac pacemaker function by interactions of cAMP-mediated PKA-dependent Ca2+ cycling with surface membrane channels.

  2009cited by this paper
• Diversity and Developmental Expression of L-type Calcium Channel β2 Proteins and Their Influence on Calcium Current in Murine Heart*

  2009cited by this paper
• Transcriptional and electrophysiological consequences of KChIP2-mediated regulation of CaV1.2

  2009cited by this paper
• Asthma and sarcoplasmic reticulum Ca2+ reuptake in airway smooth muscle.

  2009influential reference
• The contribution of Ca2+ signaling and Ca2+ sensitivity to the regulation of airway smooth muscle contraction is different in rats and mice.

  2009cited by this paper
• Unchanged β-Adrenergic Stimulation of Cardiac L-type Calcium Channels in Cav1.2 Phosphorylation Site S1928A Mutant Mice*

  2008cited by this paper
• The suppressive effects of YM-58483/BTP-2, a store-operated Ca2+ entry blocker, on inflammatory mediator release in vitro and airway responses in vivo.

  2008cited by this paper
• Regulation of sarcoplasmic reticulum Ca2+ reuptake in porcine airway smooth muscle.

  2008influential reference
• Regulation of store-operated Ca2+ entry by CD38 in human airway smooth muscle.

  2008cited by this paper
• Role of CaV&bgr; Subunits, and Lack of Functional Reserve, in Protein Kinase A Modulation of Cardiac CaV1.2 Channels

  2008cited by this paper
• Calcium cycling and signaling in cardiac myocytes.

  2008cited by this paper
• A modular switch for spatial Ca2+ selectivity in the calmodulin regulation of CaV channels

  2008cited by this paper
• ORAI and store-operated calcium influx in human airway smooth muscle cells.

  2008cited by this paper
• Sustained Activation of the Tyrosine Kinase Syk by Antigen in Mast Cells Requires Local Ca2+ Influx through Ca2+ Release-activated Ca2+ Channels*

  2008cited by this paper
• Airway smooth muscle dynamics: a common pathway of airway obstruction in asthma.

  2007cited by this paper
• Acetylcholine-induced asynchronous calcium waves in intact human bronchial muscle bundle.

  2007cited by this paper
• PKA-I holoenzyme structure reveals a mechanism for cAMP-dependent activation.

  2007cited by this paper
• Inositol trisphosphate receptor Ca2+ release channels.

  2007cited by this paper
• The molecular choreography of a store-operated calcium channel

  2007cited by this paper
• AKAP signaling complexes: getting to the heart of the matter.

  2006cited by this paper
• A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function

  2006influential reference
• A key role for STIM1 in store operated calcium channel activation in airway smooth muscle

  2006cited by this paper
• Airway smooth muscle relaxation results from a reduction in the frequency of Ca2+ oscillations induced by a cAMP-mediated inhibition of the IP3 receptor

  2006cited by this paper
• Mechanism of ACh-induced asynchronous calcium waves and tonic contraction in porcine tracheal muscle bundle.

  2006cited by this paper
• Regulation of Maximal Open Probability Is a Separable Function of Cavβ Subunit in L-type Ca2+ Channel, Dependent on NH2 Terminus of α1C (Cav1.2α)

  2006cited by this paper
• Autoinhibitory control of the CaV1.2 channel by its proteolytically processed distal C‐terminal domain

  2006cited by this paper
• Excitation-Contraction Coupling in Airway Smooth Muscle*

  2006cited by this paper
• Store-operated Ca 2 (cid:1) Influx in Airway Smooth Muscle Interactions between Volatile Anesthetic and Cyclic Nucleotide Effects

  2006cited by this paper
• Modulation of the Ca2+ sensitivity of airway smooth muscle cells in murine lung slices.

  2006cited by this paper
• &bgr;-Adrenergic Stimulation of L-type Ca2 Channels in Cardiac Myocytes Requires the Distal Carboxyl Terminus of &agr;1C but Not Serine 1928

  2006cited by this paper
• Localization of cardiac L-type Ca(2+) channels to a caveolar macromolecular signaling complex is required for beta(2)-adrenergic regulation.

  2006cited by this paper
• Intracellular calcium release and cardiac disease.

  2005cited by this paper
• Crystal Structure of a Complex Between the Catalytic and Regulatory (RIα) Subunits of PKA

  2005cited by this paper
• Store-operated calcium channels.

  2005cited by this paper
• Preferential Phosphorylation of R-domain Serine 768 Dampens Activation of CFTR Channels by PKA

  2005cited by this paper
• RNA Silencing Identifies PDE4D5 as the Functionally Relevant cAMP Phosphodiesterase Interacting with βArrestin to Control the Protein Kinase A/AKAP79-mediated Switching of the β2-Adrenergic Receptor to Activation of ERK in HEK293B2 Cells*

  2005cited by this paper
• STIM1, an essential and conserved component of store-operated Ca2+ channel function

  2005influential reference
• The Frequency of Calcium Oscillations Induced by 5-HT, ACH, and KCl Determine the Contraction of Smooth Muscle Cells of Intrapulmonary Bronchioles

  2005cited by this paper
• STIM is a Ca2+ sensor essential for Ca2+-store-depletion-triggered Ca2+ influx.

  2005cited by this paper
• Sites of proteolytic processing and noncovalent association of the distal C-terminal domain of CaV1.1 channels in skeletal muscle.

  2005cited by this paper
• Modulation of excitation–contraction coupling by isoproterenol in cardiomyocytes with controlled SR Ca2+ load and Ca2+ current trigger

  2004cited by this paper
• Store-operated Ca2+ entry in porcine airway smooth muscle.

  2004cited by this paper
• PI3K promotes voltage-dependent calcium channel trafficking to the plasma membrane

  2004cited by this paper
• Tissue‐specific expression of two human Cav1.2 isoforms under the control of distinct 5′ flanking regulatory elements

  2003cited by this paper
• Calcium signalling: dynamics, homeostasis and remodelling

  2003influential reference
• A Novel Long N-terminal Isoform of Human L-type Ca2+Channel Is Up-regulated by Protein Kinase C*

  2002cited by this paper
• A new promoter for alpha1C subunit of human L-type cardiac calcium channel Ca(V)1.2.

  2002cited by this paper
• Ionic mechanisms and Ca(2+) regulation in airway smooth muscle contraction: do the data contradict dogma?

  2002cited by this paper

• Role of voltage-gated Ca2+ channels and Ano1 Ca2+-activated Cl- channels in M2 muscarinic receptor-dependent contractions of murine airway smooth muscle.

  2025cites this paper
• Mechanically induced dysregulation of calcium homeostasis: a molecular linchpin in asthmatic pathogenesis

  2025cites this paper
• Magnoliae Officinalis Cortex volatile oil alleviated asthma via dual cAMP-mediated Pathways: Anti-Inflammation and Bronchodilation.

  2025cites this paper
• Amitriptyline inhibits bronchoconstriction independent of direct receptor binding and reduces number of caveolae

  2025cites this paper
• Store-operated Ca2+ entry contributes to the ASM phenotype transition in asthma

  2025cites this paper
• Precision cut lung slices: an integrated ex vivo model for studying lung physiology, pharmacology, disease pathogenesis and drug discovery

  2024cites this paper
• High throughput screening of airway constriction in mouse lung slices

  2024cites this paper
• IL-37 protects against house dust mite-induced airway inflammation and airway epithelial barrier dysfunction via inhibiting store-operated calcium entry.

  2024cites this paper
• Calcium Signaling in Airway Epithelial Cells: Current Understanding and Implications for Inflammatory Airway Disease

  2024cites this paper
• ORAI Calcium Channels: Regulation, Function, Pharmacology, and Therapeutic Targets

  2023cites this paper
• Reactive Oxygen Species Behaving Badly: Oxidized Phosphatidylcholines Corrupt Ca2+ Signaling in Airway Smooth Muscle

  2023cites this paper
• Ca2+ dynamics in interstitial cells: foundational mechanisms for the motor patterns in the gastrointestinal tract.

  2023cites this paper
• Inherent differences of small airway contraction and Ca2+ oscillations in airway smooth muscle cells between BALB/c and C57BL/6 mouse strains

  2023influential citation
• Exercise Reduces Airway Smooth Muscle Contraction in Asthmatic Rats via Inhibition of IL-4 Secretion and Store-Operated Ca2+ Entry Pathway

  2023cites this paper
• Excitatory cholinergic responses in mouse primary bronchial smooth muscle require both Ca2+ entry via l-type Ca2+ channels and store operated Ca2+ entry via Orai channels.

  2023cites this paper
• Menthol Flavoring in E-Cigarette Condensate Causes Pulmonary Dysfunction and Cytotoxicity in Precision Cut Lung Slices.

  2023cites this paper
• Ca2+ signalling in interstitial cells of Cajal contributes to generation and maintenance of tone in mouse and monkey lower oesophageal sphincters

  2022cites this paper
• Glucose- and glutamine-dependent bioenergetics sensitize bone mechanoresponse after unloading by modulating osteocyte calcium dynamics

  2022cites this paper
• The role of mathematical models in designing mechanopharmacological therapies for asthma

  2022cites this paper
• Airway smooth muscle function in asthma

  2022cites this paper
• Imidazobenzodiazepine PI320 Relaxes Mouse Peripheral Airways by Inhibiting Calcium Mobilization.

  2022cites this paper
• Modulation of carbachol-induced Ca2+ oscillations in airway smooth muscle cells by PGE2.

  2022cites this paper
• The Emerging Role of Ion Channels in the Pathophysiology and Treatments of Asthma

  2021cites this paper
• Ca2+ signaling driving pacemaker activity in submucosal interstitial cells of Cajal in the murine colon

  2021cites this paper
• Nimodipine inhibits intestinal and aortic smooth muscle contraction by regulating Ca2+-activated Cl- channels.

  2021cites this paper
• Development of Store-Operated Calcium Entry-Targeted Compounds in Cancer

  2021cites this paper
• Store-operated Calcium Entry-associated Regulatory Factor Regulates Airway Inflammation and Airway Remodeling in Asthma Mice Models.

  2021cites this paper
• Ca2+ transients in ICC-MY define the basis for the dominance of the corpus in gastric pacemaking.

  2021cites this paper
• Transient receptor potential cation channel subfamily V (TRPV) and its importance in asthma.

  2021cites this paper
• ORAI1 regulates sustained cytosolic free calcium fluctuations during breast cancer cell apoptosis and apoptotic resistance via a STIM1 independent pathway

  2021cites this paper
• Transition behavior of the seizure dynamics modulated by the astrocyte inositol triphosphate noise.

  2021cites this paper
• Sarcoplasmic reticulum and calcium signaling in muscle cells: Homeostasis and disease.

  2020cites this paper
• Effect of Calcium and Vitamin D Co-supplementation on Blood Pressure: a Systematic Review and Meta-Analysis.

  2020cites this paper
• Folium Sennae and emodin reverse airway smooth muscle contraction

  2020cites this paper
• Extracellular Vesicles Derived from Human Umbilical Cord Mesenchymal Stem Cells Protect Liver Ischemia/Reperfusion Injury by Reducing CD154 Expression on CD4+ T Cells via CCT2

  2020cites this paper
• Folium Sennae and emodin reverse airway smooth muscle contraction.

  2020cites this paper
• Ca2+ signaling driving pacemaker activity in submucosal interstitial cells of Cajal in the colon

  2020cites this paper
• NS8593 inhibits Ca2+ permeant channels reversing mouse airway smooth muscle contraction.

  2019cites this paper
• Regulation of Airway Smooth Muscle Contraction in Health and Disease.

  2019cites this paper
• Functional relaxant effect of 6,7-dipropoxy-2H-chromen-2-one is mainly by calcium channel blockade in ex vivo assay of tracheal rings

  2019cites this paper
• Protease‐activated receptor 2 activates CRAC‐mediated Ca2+ influx to cause prostate smooth muscle contraction

  2019cites this paper
• Flavored E-liquids Increase Cytoplasmic Ca2+ Levels in Airway Epithelia.

  2019cites this paper
• ORAI channels in cellular remodeling of cardiorespiratory disease.

  2019cites this paper
• Imaging elemental events of store-operated Ca2+ entry in invading cancer cells with plasmalemmal targeted sensors

  2019cites this paper
• Functional mechanism of tracheal relaxation, antiasthmatic, and toxicological studies of 6‐hydroxyflavone

  2019cites this paper
• Roles of LRRC26 as an auxiliary γ1-subunit of large-conductance Ca2+-activated K+ channels in bronchial smooth muscle cells.

  2019cites this paper
• A novel GABAA receptor ligand MIDD0301 with limited blood-brain barrier penetration relaxes airway smooth muscle ex vivo and in vivo.

  2019cites this paper
• Mitochondrial regulation of airway smooth muscle functions in health and pulmonary diseases.

  2019cites this paper
• Generation and Role of Oscillatory Contractions in Mouse Airway Smooth Muscle

  2018cites this paper
• Cigarette smoke up‐regulates PDE3 and PDE4 to decrease cAMP in airway cells

  2018cites this paper
• TGF‐&bgr;1‐Induced Airway Smooth Muscle Cell Proliferation Involves TRPM7‐Dependent Calcium Influx via TGF&bgr;R/SMAD3

  2018cites this paper
• Chronic alcohol feeding potentiates hormone‐induced calcium signalling in hepatocytes

  2017cites this paper
• Airway smooth muscle dysfunction in Pompe (Gaa-/- ) mice.

  2017cites this paper
• Role of transient receptor potential vanilloid 1 in the modulation of airway smooth muscle tone and calcium handling.

  2017cites this paper
• Secondary Metabolites in Allergic Plant Pollen Samples Modulate Afferent Neurons and Murine Tracheal Rings.

  2017cites this paper
• The relative contributions of store‐operated and voltage‐gated Ca2+ channels to the control of Ca2+ oscillations in airway smooth muscle

  2017cites this paper