Age-related changes in the fracture resistance of male Fischer F344 rat bone.

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Bone

• Publication date

  2016-02-01

• Fields of study

  Biology, Medicine, Materials Science, Chemistry

• Identifiers
  DOI 10.1016/j.bone.2015.11.009PMID 26610688PMCID PMC4724327
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2010influential reference
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  2001cited by this paper
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  2001cited by this paper
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• Changes in the stiffness, strength, and toughness of human cortical bone with age.

  1998cited by this paper
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  1997cited by this paper
• Diabetic and age-related enhancement of collagen-linked fluorescence in cortical bones of rats.

  1994cited by this paper
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  1994cited by this paper
• Basic biomechanical measurements of bone: a tutorial.

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  1993cited by this paper
• Bone mechanical properties after exercise training in young and old rats.

  1990cited by this paper
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  1982cited by this paper
• Aging of bone tissue: mechanical properties.

  1976cited by this paper

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