Mycothiol, 1‐O‐(2′‐[N‐acetyl‐L‐cysteinyl]amido‐2′‐deoxy‐α‐D‐glucopyranosyl)‐D‐myo‐inositol, is the factor of NAD/factor‐dependent formaldehyde dehydrogenase

No abstract is available for this paper.

• Publication year

  1997

• Venue

  FEBS Letters

• Publication date

  1997-06-09

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1016/S0014-5793(97)00510-3PMID 9202149
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Distribution of thiols in microorganisms: mycothiol is a major thiol in most actinomycetes

  1996cited by this paper
• A second molybdoprotein aldehyde dehydrogenase from Amycolatopsis methanolica NCIB 11946.

  1996cited by this paper
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  1995cited by this paper
• The structure of U17 isolated from Streptomyces clavuligerus and its properties as an antioxidant thiol.

  1995cited by this paper
• NAD- and co-substrate (GSH or factor)-dependent formaldehyde dehydrogenases from methylotrophic microorganisms act as a class III alcohol dehydrogenase

  1994cited by this paper
• Structure of a novel disulfide of 2-(N-acetylcysteinyl)amido-2-deoxy-alpha-D-glucopyranosyl-myo-inositol produced by Streptomyces sp.

  1994cited by this paper
• Fundamental molecular differences between alcohol dehydrogenase classes.

  1994cited by this paper
• Thiols of intracellular pathogens. Identification of ovothiol A in Leishmania donovani and structural analysis of a novel thiol from Mycobacterium bovis.

  1994cited by this paper
• Distribution of alcohol and sorbitol dehydrogenases. Assessment of mRNA species in mammalian tissues.

  1993cited by this paper
• NAD-linked, factor-dependent formaldehyde dehydrogenase or trimeric, zinc-containing, long-chain alcohol dehydrogenase from Amycolatopsis methanolica.

  1992cited by this paper
• Dye-linked dehydrogenase activities for formate and formate esters in Amycolatopsis methanolica. Characterization of a molybdoprotein enzyme active with formate esters and aldehydes.

  1992cited by this paper
• Evidence for the identity of glutathione‐dependent formaldehyde dehydrogenase and class III alcohol dehydrogenase

  1989cited by this paper
• The formaldehyde dehydrogenase of Rhodococcus erythropolis, a trimeric enzyme requiring a cofactor and active with alcohols.

  1985cited by this paper
• Formaldehyde dehydrogenase from human liver. Purification, properties, and evidence for the formation of glutathione thiol esters by the enzyme.

  1974cited by this paper

• Methanol metabolism in synthetic methylotrophic microorganisms.

  2025cites this paper
• Mitigating toxic formaldehyde to promote efficient utilization of C1 resources

  2024cites this paper
• Unique alcohol dehydrogenases involved in algal sugar utilization by marine bacteria

  2023cites this paper
• Mechanistic insights into sulfur source-driven physiological responses and metabolic reorganization in the fuel-biodesulfurizing Rhodococcus qingshengii IGTS8

  2023cites this paper
• Unravelling Formaldehyde Metabolism in Bacteria: Road towards Synthetic Methylotrophy

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• Great South African molecules: the case for mycothiol

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• Guidance for engineering of synthetic methylotrophy based on methanol metabolism in methylotrophy

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• Engineering of Corynebacterium glutamicum towards utilization of Methanol as carbon and energy source

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• Genomes of Planktonic Acidimicrobiales: Widening Horizons for Marine Actinobacteria by Metagenomics

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• Production of carbon-13-labeled cadaverine by engineered Corynebacterium glutamicum using carbon-13-labeled methanol as co-substrate

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• Biosynthetic and functional studies of bacillithiol in gram-positive bacteria

  2015cites this paper
• Oxidation of Methanol to Carbon Dioxide glutamicum: an Endogenous Pathway for Metabolism in Corynebacterium 1 C

  2014cites this paper
• Mycothiol: a promising antitubercular target.

  2014cites this paper
• 7 Aerobic Methylotrophic Prokaryotes

  2013cites this paper
• C1 Metabolism in Corynebacterium glutamicum: an Endogenous Pathway for Oxidation of Methanol to Carbon Dioxide

  2013cites this paper
• New targets and inhibitors of mycobacterial sulfur metabolism.

  2013cites this paper
• Physiological roles of mycothiol in detoxification and tolerance to multiple poisonous chemicals in Corynebacterium glutamicum

  2013cites this paper
• Glutathione analogs in prokaryotes.

  2013cites this paper
• Low-Molecular-Weight Thiols in Thiol–Disulfide Exchange

  2013cites this paper
• Formaldehyde degradation in Corynebacterium glutamicum involves acetaldehyde dehydrogenase and mycothiol-dependent formaldehyde dehydrogenase.

  2013cites this paper
• Corynebacterium glutamicum harbours a molybdenum cofactor-dependent formate dehydrogenase which alleviates growth inhibition in the presence of formate.

  2012cites this paper
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  2011influential citation
• Characterisation of the enzymes involved in methanol dissimilation in Bacillus methanolicus : assessment of enzyme-based biohydrogen production for a cell-free biofuel cell

  2010cites this paper
• Mycothiol disulfide reductase as a drug target

  2010cites this paper
• Arsenate Reductase, Mycothiol, and Mycoredoxin Concert Thiol/Disulfide Exchange*

  2009cites this paper
• Redox control in actinobacteria.

  2008cites this paper
• Mycothiol: synthesis, biosynthesis and biological functions of the major low molecular weight thiol in actinomycetes.

  2008cites this paper
• Biosynthesis and Functions of Mycothiol, the Unique Protective Thiol of Actinobacteria

  2008cites this paper
• Drug targets in mycobacterial sulfur metabolism.

  2007cites this paper
• Mycothiol-dependent proteins in actinomycetes.

  2007cites this paper
• Evolution of the diverse biological roles of inositols.

  2007cites this paper
• Identification of genes for mycothiol biosynthesis in Streptomyces coelicolor A3(2).

  2006cites this paper
• The Gene ncgl2918 Encodes a Novel Maleylpyruvate Isomerase That Needs Mycothiol as Cofactor and Links Mycothiol Biosynthesis and Gentisate Assimilation in Corynebacterium glutamicum*

  2006cites this paper
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  2005cites this paper
• A Family of Mycothiol Analogues

  2005cites this paper
• Thiosugars: new perspectives regarding availability and potential biochemical and medicinal applications

  2005cites this paper
• Crystal structure of MshB from Mycobacterium tuberculosis, a deacetylase involved in mycothiol biosynthesis.

  2004cites this paper
• Association of mycothiol with protection of Mycobacterium tuberculosis from toxic oxidants and antibiotics

  2003cites this paper
• The Crystal Structure of 1-D-myo-Inosityl 2-Acetamido-2-deoxy-α-D-glucopyranoside Deacetylase (MshB) from Mycobacterium tuberculosis Reveals a Zinc Hydrolase with a Lactate Dehydrogenase Fold*

  2003cites this paper
• The metabolism of nitrosothiols in the Mycobacteria: identification and characterization of S-nitrosomycothiol reductase.

  2003cites this paper
• Characterization of Mycobacterium tuberculosis mycothiol S-conjugate amidase.

  2003cites this paper
• Shortcut to mycothiol analogues.

  2002cites this paper
• Synthesis of mycothiol, 1D-1-O-(2-[N-acetyl-L-cysteinyl]amino-2-deoxy-alpha-D-glucopyranosyl)-myo-inositol, principal low molecular mass thiol in the actinomycetes.

  2002cites this paper
• Mycothiol biochemistry

  2002cites this paper
• Unity and diversity in biological oxidation

  2002cites this paper
• Cofactor-dependent pathways of formaldehyde oxidation in methylotrophic bacteria

  2002cites this paper
• Identification of the mycothiol synthase gene (mshD) encoding the acetyltransferase producing mycothiol in actinomycetes

  2002cites this paper
• ATP-dependent L-cysteine:1D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase, mycothiol biosynthesis enzyme MshC, is related to class I cysteinyl-tRNA synthetases.

  2002cites this paper
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  2000cites this paper
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  2000influential citation
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  2000cites this paper
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  1999cites this paper
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  1999cites this paper
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  1999cites this paper
• Improved Methods for Immunoassay of Mycothiol

  1999cites this paper
• Mycothiol Biosynthesis and Metabolism

  1998cites this paper
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  1998cites this paper
• Induction of glutathione-dependent formaldehyde dehydrogenase activity in Escherichia coli and Hemophilus influenza.

  1997cites this paper
• Mycothiol-dependent formaldehyde dehydrogenase, a prokaryotic medium-chain dehydrogenase/reductase, phylogenetically links different eukaroytic alcohol dehydrogenases--primary structure, conformational modelling and functional correlations.

  1997cites this paper