Molecular cloning of the cDNA and chromosomal localization of the gene for a putative seven-transmembrane segment (7-TMS) receptor isolated from human spleen.

No abstract is available for this paper.

• Publication year

  1993

• Venue

  Genomics

• Publication date

  1993-06-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1006/GENO.1993.1251PMID 8325644
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Cloning and functional expression of a human neuropeptide Y/peptide YY receptor of the Y1 type.

  1992cited by this paper
• Identification of cultured cells selectively expressing Y1-, Y2-, or Y3-type receptors for neuropeptide Y/peptide YY.

  1992cited by this paper
• The human protein-tyrosine phosphatase PTP alpha/LRP gene (PTPA) is assigned to chromosome 20p13.

  1992cited by this paper
• Cloned human neuropeptide Y receptor couples to two different second messenger systems.

  1992cited by this paper
• Neuropeptide Y and neuropeptide Y receptor subtypes in brain and peripheral tissues.

  1992cited by this paper
• CLUSTAL V: improved software for multiple sequence alignment

  1992cited by this paper
• Interleukin‐8, a chemotactic and inflammatory cytokine

  1992cited by this paper
• Cytomegalovirus homologs of cellular G protein-coupled receptor genes are transcribed

  1991cited by this paper
• Sequence and expression of a neuropeptide Y receptor cDNA.

  1991cited by this paper
• Molecular characterization of the interleukin-8 receptor.

  1991cited by this paper
• Cloning and expression of the human vasoactive intestinal peptide receptor.

  1991cited by this paper
• The interleukin-8 receptor is encoded by a neutrophil-specific cDNA clone, F3R.

  1991cited by this paper
• Properties of the novel proinflammatory supergene "intercrine" cytokine family.

  1991cited by this paper
• Receptors for neuropeptide Y: multiple subtypes and multiple second messengers.

  1991cited by this paper
• Structure and functional expression of a human interleukin-8 receptor.

  1991cited by this paper
• Model systems for the study of seven-transmembrane-segment receptors.

  1991cited by this paper
• Cloning of complementary DNA encoding a functional human interleukin-8 receptor.

  1991cited by this paper
• Synthesis and use of a novel N-formyl peptide derivative to isolate a human N-formyl peptide receptor cDNA.

  1990cited by this paper
• Human cytomegalovirus encodes three G protein-coupled receptor homologues

  1990cited by this paper
• Reconstructing evolution of sequences subject to recombination using parsimony.

  1990cited by this paper
• Molecular cloning of a novel G protein‐coupled receptor that may belong to the neuropeptide receptor family

  1990cited by this paper
• Molecular cloning of the fMet-Leu-Phe receptor from neutrophils.

  1990cited by this paper
• Establishment of a human cell line (mono mac 6) with characteristics of mature monocytes

  1988cited by this paper
• Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction.

  1987cited by this paper
• The HL-60 promyelocytic leukemia cell line: proliferation, differentiation, and cellular oncogene expression.

  1987cited by this paper
• An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs.

  1987cited by this paper
• High-resolution chromosomal localization of the beta-gene of the human beta-globin gene complex by in situ hybridization.

  1985cited by this paper
• Localization of single copy DNA sequences on G-banded human chromosomes by in situ hybridization

  1981cited by this paper

• The complex nature of CXCR4 mutations in WHIM syndrome

  2024cites this paper
• SDF-1α/CXCR4 signaling promotes capillary tube formation of human retinal vascular endothelial cells by activating ERK1/2 and PI3K pathways in vitro

  2022cites this paper
• Inflammatory pathways in pathological neovascularization in retina and choroid: a narrative review on the inflammatory drug target molecules in retinal and choroidal neovascularization

  2021cites this paper
• Analysis of Genetic Differences in Genes Associated with Immune Response Among Purebred and Crossbreed Sistani and Montebeliarde Cow Populations using RNA-Seq Data

  2021cites this paper
• Correlation between single nucleotide polymorphisms in CXCR4 microRNA binding site and the susceptibility to knee osteoarthritis in Han Chinese population

  2020cites this paper
• WHIM Syndrome: from Pathogenesis Towards Personalized Medicine and Cure

  2019cites this paper
• The CXC chemokines and CXC chemokine receptors in orange‐spotted grouper (Epinephelus coioides) and their expression after Singapore grouper iridovirus infection

  2019cites this paper
• Design and evaluation of a CXCR4 targeting peptide 4DV3 as an HIV entry inhibitor and a ligand for targeted drug delivery

  2019cites this paper
• Isolated metastasis of an EGFR-L858R-mutated NSCLC of the meninges: the potential impact of CXCL12/CXCR4 axis in EGFRmut NSCLC in diagnosis, follow-up and treatment

  2018influential citation
• Role of CXCR4 and SDF1 as prognostic factors for survival and the association with clinicopathology in colorectal cancer: A systematic meta-analysis

  2017cites this paper
• SDF-1/CXCL12 and CXCR4 gene variants, and elevated serum SDF-1 levels are associated with preeclampsia

  2017cites this paper
• Human Immunodeficiency Virus Immune Cell Receptors, Coreceptors, and Cofactors: Implications for Prevention and Treatment

  2016cites this paper
• CXC motif chemokine receptor 4 gene polymorphism and cancer risk

  2016cites this paper
• Potential of CXCR4/CXCL12 Chemokine Axis in Cancer Drug Delivery

  2016cites this paper
• CXCR4 polymorphism predicts progression-free survival in metastatic colorectal cancer patients treated with first-line bevacizumab-based chemotherapy

  2016cites this paper
• Genetic Polymorphism and Expression of CXCR4 in Breast Cancer

  2015cites this paper
• CXCL12 genetic variants as prognostic markers in nasopharyngeal carcinoma

  2015cites this paper
• Effect of truncated neurokinin‐1 receptor expression changes on the interaction between human breast cancer and bone marrow‐derived mesenchymal stem cells

  2014influential citation
• CXCR4 as a target for preclinical Positron Emission Tomography of cancer

  2013cites this paper
• Association of CXCL12 and CXCR4 gene polymorphisms with the susceptibility and prognosis of renal cell carcinoma.

  2013cites this paper
• chemokine stromal-derived factor-1 Regulation of endothelial cell branching morphogenesis by endogenous

  2013cites this paper
• The Differences in CXCR4 Protein Expression Are Significant for the Five Molecular Subtypes of Breast Cancer

  2012cites this paper
• Inhibition of stromal CXCR4 impairs development of lung metastases

  2012cites this paper
• The biological behavior of SDF-1/CXCR4 in patients with myelodysplastic syndrome

  2012cites this paper
• Grouper (Epinephelus coioides) CXCR4 is expressed in response to pathogens infection and early stage of development.

  2012cites this paper
• Genetic variants of SDF-1 and CXCR4 genes in endometrial carcinoma

  2012cites this paper
• Hypoxia Specific SDF-1 Expression by Retinal Pigment Epithelium Initiates Bone Marrow-derived Cells to Participate in Choroidal Neovascularization in a Laser-induced Mouse Model

  2011cites this paper
• Critical role of SDF-1α-induced progenitor cell recruitment and macrophage VEGF production in the experimental corneal neovascularization

  2011cites this paper
• CXCR4 and Axillary Lymph Nodes: Review of a Potential Biomarker for Breast Cancer Metastasis

  2011cites this paper
• Pillars article: HIV-1 entry cofactor: functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor. Science. 1996. 272: 872-877.

  2011cites this paper
• Association of genetic polymorphisms of CXCL12/SDF1 gene and its receptor, CXCR4, to the susceptibility and prognosis of non-small cell lung cancer.

  2011cites this paper
• Hematopoietic Derived Cell Infiltration of the Intestinal Tumor Microenvironment in ApcMin/+ Mice

  2011cites this paper
• Caractérisation d’un modèle murin du Syndrome WHIM (Souris Cxcr4+/1013)

  2011cites this paper
• Th17 Cells Induce Colitis and Promote Th1 Cell Responses through IL-17 Induction of Innate IL-12 and IL-23 Production

  2011cites this paper
• Influence of CXCR4/SDF-1 axis on E-cadherin/β-catenin complex expression in HT29 colon cancer cells.

  2011cites this paper
• PET imaging of CXCR4 using copper-64 labeled peptide antagonist

  2011cites this paper
• Fusing HIV and Chemokine Receptors

  2011cites this paper
• CXCR4 as a Therapeutic Target

  2011cites this paper
• Expression of the chemokine receptor CXCR4 in human hepatocellular carcinoma and its role in portal vein tumor thrombus

  2010cites this paper
• Crystalline Ultrastructures, Inflammatory Elements, and Neoangiogenesis Are Present in Inconspicuous Aortic Valve Tissue

  2010cites this paper
• Stem cell biology in health and disease

  2010cites this paper
• Evaluation of CXCR4 inhibition in the prevention and intervention model of laser-induced choroidal neovascularization.

  2010cites this paper
• Die Bedeutung der Chemokinrezeptoren CCR7 und CXCR4 sowie des CCR7-Liganden CCL21 für die Ausbreitung des duktalen Adenokarzinoms des Pankreas

  2010cites this paper
• Role of the CXCR4/CXCL12 signaling axis in breast cancer metastasis to the brain

  2010cites this paper
• Increased CXCR4 expression in AsPC1 pancreatic carcinoma cells with RNA interference-mediated knockdown of DNMT1 and DNMT3B.

  2010cites this paper
• The biology of CCR5 and CXCR4

  2009cites this paper
• Contribution of genetic polymorphisms of stromal cell–derived factor‐1 and its receptor, CXCR4, to the susceptibility and clinicopathologic development of oral cancer

  2009cites this paper
• A novel role for the chemokine receptor Cxcr4 in kidney morphogenesis: An in vitro study

  2009cites this paper
• Modulation of Hematopoietic Stem/Progenitor Cell Migration

  2009cites this paper
• Stromal cell-derived factor-1 but not its receptor, CXCR4, gene variants increase susceptibility and pathological development of hepatocellular carcinoma

  2009cites this paper
• HIV Nef-M1 Effects on Colorectal Cancer Growth in Tumor-induced Spleens and Hepatic Metastasis.

  2009cites this paper
• Manipulation of the Moloney Murine Leukemia Virus envelope protein in an effort to develop directly and indirectly targeted retroviral vectors for use in human gene therapy

  2008cites this paper
• Attenuation of obliterative bronchiolitis by a CXCR4 antagonist in the murine heterotopic tracheal transplant model.

  2008cites this paper
• Recombinant CXCR4/CCR5 hybrid receptors as tools for studies of HIV-1 receptor usage

  2007cites this paper
• The SDF‐1/CXCR4 ligand/receptor pair is an important contributor to several types of ocular neovascularization

  2007cites this paper
• Stem cell migration: a quintessential stepping stone to successful therapy.

  2007cites this paper
• Characterization of cDNA and genomic sequences encoding a canine chemokine receptor, CXCR4 and its ligand CXCL12.

  2007cites this paper
• Genetic aspects of HIV-1 risk in an African setting

  2006cites this paper
• ROLE OF STROMAL CELL-DERIVED FACTOR 1 IN PROLIFERATIVE RETINOPATHY

  2006cites this paper
• Stromal cell-derived factor-1 and CXCR4 receptor interaction in tumor growth and metastasis of breast cancer.

  2006cites this paper
• G-CSF down-regulation of CXCR4 expression identified as a mechanism for mobilization of myeloid cells.

  2006cites this paper
• Cloning and characterizing mutated human stromal cell-derived factor-1 (SDF-1): C-terminal alpha-helix of SDF-1alpha plays a critical role in CXCR4 activation and signaling, but not in CXCR4 binding affinity.

  2006cites this paper
• Gene silencing of HIV chemokine receptors using ribozymes and single-stranded antisense RNA.

  2006cites this paper
• Role of the Cys18-Cys274 disulfide bond and of the third extracellular loop in the constitutive activation and internalization of angiotensin II type 1 receptor.

  2006cites this paper
• Risk for HIV-1 Infection Associated With a Common CXCL12 (SDF1) Polymorphism and CXCR4 Variation in an African Population

  2005cites this paper
• Overview and History of Chemokines and Their Receptors

  2005cites this paper
• Blockade of the stromal cell-derived factor-1/CXCR4 axis attenuates in vivo tumor growth by inhibiting angiogenesis in a vascular endothelial growth factor-independent manner.

  2005cites this paper
• Differential processing of stromal-derived factor-1alpha and stromal-derived factor-1beta explains functional diversity.

  2004cites this paper
• Chemotactic peptides encoded by hiv-1 nef gene

  2004cites this paper
• Transcriptional targeting in renal cancer cell lines via the human CXCR4 promoter.

  2004cites this paper
• Involvement of the chemokine receptor CXCR4 and its ligand stromal cell-derived factor 1alpha in breast cancer cell migration through human brain microvascular endothelial cells.

  2004cites this paper
• Differential processing of stromal-derived factor-1α and stromal-derived factor-1β explains functional diversity

  2004cites this paper
• The role of chemokine receptors in the promotion of viral infections.

  2003cites this paper
• Selective expression of stromal-derived factor-1 in the capillary vascular endothelium plays a role in Kaposi sarcoma pathogenesis.

  2003cites this paper
• Tannic Acid Is an Inhibitor of CXCL12 (SDF-1α)/CXCR4 with Antiangiogenic Activity

  2003cites this paper
• Serum inactivation contributes to the failure of stromal‐derived factor‐1 to block HIV‐I infection in vivo

  2003cites this paper
• Binding Affinities of Various Chemokines Comparing CC CKR 3 Expressed in AML 14 . 3010 with Primary Eosinophils

  2003cites this paper
• Tannic acid is an inhibitor of CXCL12 (SDF-1alpha)/CXCR4 with antiangiogenic activity.

  2003cites this paper
• Characterization of the Rhesus Cytomegalovirus US28 Locus

  2003cites this paper
• CHAPTER 46 – Interleukin-8 and other CXC chemokines

  2003cites this paper
• Suradista NSC 651016 Inhibits the Angiogenic Activity of CXCL12-Stromal Cell-derived Factor 1 (cid:1) 1

  2002cites this paper
• Regional Expression of CXCL12/CXCR4 in Liver and Hepatocellular Carcinoma and Cell‐cycle Variation during in vitro Differentiation

  2002cites this paper
• Suradista NSC 651016 inhibits the angiogenic activity of CXCL12-stromal cell-derived factor 1alpha.

  2002cites this paper
• Interleukin-6 and cAMP Induce Stromal Cell-derived Factor-1 Chemotaxis in Astroglia by Up-regulating CXCR4 Cell Surface Expression

  2002cites this paper
• Regulation of endothelial cell branching morphogenesis by endogenous chemokine stromal-derived factor-1.

  2002cites this paper
• Constitutive Roles for SDF-1/CXCR4 and Fractalkine/CX3CR1 in the CNS

  2002cites this paper
• Macrophages, chemokines and neuronal injury in HIV-1-associated dementia.

  2002cites this paper
• DNAWorks: an automated method for designing oligonucleotides for PCR-based gene synthesis.

  2002cites this paper
• Stromal-derived factor 1 inhibits the cycling of very primitive human hematopoietic cells in vitro and in NOD / SCID mice

  2002cites this paper
• A molecular compendium of genes expressed in multiple myeloma.

  2002cites this paper
• Human B Cells Become Highly Responsive to Macrophage-Inflammatory Protein-3α/CC Chemokine Ligand-20 After Cellular Activation Without Changes in CCR6 Expression or Ligand Binding

  2002cites this paper
• Survival of B Lineage Leukemic Cells: Signals from the Bone Marrow Microenvironment

  2002cites this paper
• Chemokine receptors.

  2001cites this paper
• The diverse role of chemokines in tumor progression: prospects for intervention (Review).

  2001cites this paper
• Loss of chemokine SDF-1alpha-mediated CXCR4 signalling and receptor internalization in human hepatoma cell line HepG2.

  2001cites this paper
• Molecular characterization of important regions of the lumpy skin disease virus genome

  2001cites this paper
• Pharmacological evidence for complex and multiple site interaction of CXCR4 with SDF-1alpha: implications for development of selective CXCR4 antagonists.

  2001cites this paper
• Chemokine targets in acute brain injury and disease.

  2001cites this paper
• Chemokine receptor CCR5 and CXCR4 expression in HIV-associated kidney disease.

  2000cites this paper
• Los factores genéticos determinantes de la resistencia a la infección por VIH y del control de la progresión al SIDA: Implicaciones sobre la patogénesis y las estrategias terapéuticas para la erradicación del VIH. Una revisión

  2000cites this paper