Stimulation of leukotriene production and membrane translocation of 5-lipoxygenase by cross-linking of the IgE receptors in RBL-2H3 cells.

No abstract is available for this paper.

• Publication year

  1992

• Venue

  Biochemistry

• Publication date

  1992-04-28

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1021/BI00131A021PMID 1533155
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Slow-reacting substances, leukotrienes C4 and D4, increase the release of mucus from human airways in vitro.

  2015cited by this paper
• Determination of the activity of lipoxygenase (lipoxidase).

  2006cited by this paper
• Membrane association of active 5-lipoxygenase in resting cells. Evidence for novel regulation of the enzyme in the rat alveolar macrophage.

  1992cited by this paper
• Calcium-dependent eicosanoid metabolism by concanavalin A-stimulated human monocytes in vitro. Synergism with phorbol ester indicates separate regulation of leukotriene B4 synthesis and release.

  1991cited by this paper
• Rhinology Abstracts

  1991cited by this paper
• Influx of extracellular calcium is required for the membrane translocation of 5-lipoxygenase and leukotriene synthesis.

  1991cited by this paper
• FLAP: a novel drug target for inhibiting the synthesis of leukotrienes.

  1991cited by this paper
• Antigen- and ionophore-induced signal transduction in rat basophilic leukemia cells involves protein tyrosine phosphorylation.

  1991cited by this paper
• Regulation of arachidonic acid release in mouse peritoneal macrophages. The role of extracellular calcium and protein kinase C.

  1990cited by this paper
• Tyrosine phosphorylation coupled to IgE receptor-mediated signal transduction and histamine release.

  1990cited by this paper
• Requirement of a 5-lipoxygenase-activating protein for leukotriene synthesis

  1990cited by this paper
• MK886, a potent and specific leukotriene biosynthesis inhibitor blocks and reverses the membrane association of 5-lipoxygenase in ionophore-challenged leukocytes.

  1990cited by this paper
• Inhibition of exercise-induced bronchoconstriction by MK-571, a potent leukotriene D4-receptor antagonist.

  1990cited by this paper
• Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase.

  1990cited by this paper
• Identification and isolation of a membrane protein necessary for leukotriene production

  1990cited by this paper
• The effects of a 5-lipoxygenase inhibitor on asthma induced by cold, dry air.

  1990cited by this paper
• Sensitivity of immunoaffinity-purified porcine 5-lipoxygenase to inhibitors and activating lipid hydroperoxides.

  1989cited by this paper
• Immunoglobulin E receptor cross-linking induces oscillations in intracellular free ionized calcium in individual tumor mast cells.

  1989cited by this paper
• Thapsigargin, a novel molecular probe for studying intracellular calcium release and storage

  1989cited by this paper
• Localization and heterogeneity of agonist‐induced changes in cytosolic calcium concentration in single bovine adrenal chromaffin cells from video imaging of fura‐2.

  1989cited by this paper
• Translocation of 5-lipoxygenase to the membrane in human leukocytes challenged with ionophore A23187.

  1988cited by this paper
• Cytosolic calcium oscillators

  1988cited by this paper
• Translocation of protein kinase C in rat basophilic leukemic cells induced by phorbol ester or by aggregation of IgE receptors.

  1988cited by this paper
• Imaging asynchronous changes in intracellular Ca2+ in individual stimulated tumor mast cells.

  1988cited by this paper
• Regulation of the human leukocyte 5-lipoxygenase: stimulation by micromolar Ca2+ levels and phosphatidylcholine vesicles.

  1988cited by this paper
• Interactions of 5-lipoxygenase with membranes: studies on the association of soluble enzyme with membranes and alterations in enzyme activity.

  1988cited by this paper
• Formation of inositol 1,4,5-trisphosphate and inositol 1,3,4-trisphosphate from inositol 1,3,4,5-tetrakisphosphate and their pathways of degradation in RBL-2H3 cells.

  1988cited by this paper
• A spatial-temporal model of cell activation.

  1988cited by this paper
• Phorbol myristate acetate and the calcium ionophore A23187 synergistically induce release of LTB4 by human neutrophils: involvement of protein kinase C activation in regulation of the 5-lipoxygenase pathway.

  1987cited by this paper
• Depolarization of rat basophilic leukemia cells inhibits calcium uptake and exocytosis

  1987cited by this paper
• Synergistic signals in the mechanism of antigen-induced exocytosis in 2H3 cells: evidence for an unidentified signal required for histamine release

  1987cited by this paper
• Calcium ionophore enables soluble agonists to stimulate macrophage 5-lipoxygenase.

  1985cited by this paper
• THE EFFECT OF LEUKOTRIENE C4 ON MUCIN RELEASE INTO THE CAT TRACHEA in vivo AND in vitro

  1982cited by this paper
• IgE‐induced histamine release from rat basophilic leukemia cell lines: isolation of releasing and nonreleasing clones

  1981cited by this paper
• Slow-reacting substances (leukotrienes) contract human airway and pulmonary vascular smooth muscle in vitro

  1981cited by this paper
• Leukotrienes are potent constrictors of human bronchi

  1980cited by this paper
• The IgE‐Mast Cell System as a Paradigm for the Study of Antibody Mechanisms

  1978cited by this paper
• Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

  1970cited by this paper

• Regulation of Cytosolic Phospholipase A2 Phosphorylation by Proteolytic Cleavage of Annexin A1 in Activated Mast Cells

  2012cites this paper
• Annexin A1 in Activated Mast Cells Phosphorylation by Proteolytic Cleavage of 2 Regulation of Cytosolic Phospholipase A

  2012cites this paper
• Ethyl acetate extract of Psidium guajava inhibits IgE-mediated allergic responses by blocking FcεRI signaling.

  2011cites this paper
• The suppressive effects of YM-58483/BTP-2, a store-operated Ca2+ entry blocker, on inflammatory mediator release in vitro and airway responses in vivo.

  2008cites this paper
• A possible role for cysteinyl-leukotrienes in non-ionic contrast media induced adverse reactions.

  2005cites this paper
• Therapeutic potential of Janus kinase 3 (JAK3) inhibitors.

  2004cites this paper
• Substituted heterocyclic thiourea compounds as a new class of anti-allergic agents inhibiting IgE/Fc epsilon RI receptor mediated mast cell leukotriene release.

  2003cites this paper
• Arachidonate 5-lipoxygenase.

  2002cites this paper
• Activation of 5-lipoxygenase by cell stress is calcium independent in human polymorphonuclear leukocytes.

  2002cites this paper
• REGULATION OF LEUKOTRIENE SYNTHESIS BY ARACHIDONIC ACID IN HUMAN POLYMORPHONUCLEAR LEUKOCYTE ADHESIVE INTERACTIONS IS DEPENDENT ON THE PRESENCE OF ALBUMIN

  2002cites this paper
• Effects of inhibitors of the lipo‐oxygenase family of enzymes on the store‐operated calcium current ICRAC in rat basophilic leukaemia cells

  2002cites this paper
• Receptor-operated Ca2+ influx channels in leukocytes: a therapeutic target?

  2002cites this paper
• Elevated Levels of Cyclooxygenase-2 in Antigen-Stimulated Mast Cells Is Associated with Minimal Activation of p38 Mitogen-Activated Protein Kinase

  2001cites this paper
• The N-terminal “β-Barrel” Domain of 5-Lipoxygenase Is Essential for Nuclear Membrane Translocation*

  2001cites this paper
• Mitogen-Activated Protein Kinase with Minimal Activation of p 38 Antigen-Stimulated Mast Cells Is Associated Elevated Levels of Cyclooxygenase-2 in Beaven

  2001cites this paper
• Rac and p38 kinase mediate 5-lipoxygenase translocation and cell death.

  2001cites this paper
• Mg2+ activates 5-lipoxygenase in vitro: dependency on concentrations of phosphatidylcholine and arachidonic acid.

  2000cites this paper
• The molecular biology and regulation of 5-lipoxygenase.

  2000cites this paper
• Treatment of allergic asthma by targeting janus kinase 3-dependent leukotriene synthesis in mast cells with 4-(3', 5'-dibromo-4'-hydroxyphenyl)amino-6,7-dimethoxyquinazoline (WHI-P97).

  2000cites this paper
• 5-lipoxygenase binds calcium.

  1999cites this paper
• 5-Lipoxygenase: a target for antiinflammatory drugs revisited.

  1999cites this paper
• Targeting Janus Kinase 3 in Mast Cells Prevents Immediate Hypersensitivity Reactions and Anaphylaxis*

  1999cites this paper
• Decreased leukotriene C4 synthesis accompanies adherence-dependent nuclear import of 5-lipoxygenase in human blood eosinophils.

  1999cites this paper
• Eosinophils Import of 5-Lipoxygenase in Human Blood Accompanies Adherence-Dependent Nuclear Synthesis 4 Decreased Leukotriene C

  1999cites this paper
• Suppression of Leukotriene Formation in RBL-2H3 Cells That Overexpressed Phospholipid Hydroperoxide Glutathione Peroxidase*

  1998cites this paper
• Signal Transduction Pathways Regulating Arachidonic Acid Metabolite Generation Following FcεRI Aggregation

  1997cites this paper
• The effect of 5-lipoxygenase-activating protein (FLAP) on substrate utilization by 5-lipoxygenase.

  1997cites this paper
• Effect of interleukin-4 on allergen-induced arachidonic acid metabolism of rat peritoneal macrophages during immediate hypersensitivity reactions.

  1997cites this paper
• Arachidonate-induced eicosanoid synthesis in RBL-2H3 cells: stimulation with antigen or A23187 induces prolonged activation of 5-lipoxygenase.

  1996cites this paper
• Tyrosine Kinase Activity Modulates Catalysis and Translocation of Cellular 5-Lipoxygenase (*)

  1996cites this paper
• Oxidative inactivation of human 5-lipoxygenase in phosphatidylcholine vesicles.

  1996cites this paper
• Properties and regulation of mammalian nonpancreatic phospholipase A2 enzymes

  1996cites this paper
• Leukotriene B4 and platelet activating factor production in permeabilized human neutrophils: role of cytosolic PLA2 in LTB4 and PAF generation.

  1996cites this paper
• Development of MK 0591: An Orally Active Leukotriene Biosynthesis Inhibitor with a Novel Mechanism of Action

  1995cites this paper
• The Search for Anti-Inflammatory Drugs

  1995cites this paper
• 5-Lipoxygenase-activating protein (FLAP).

  1995cites this paper
• cDNA Cloning, Expression, Mutagenesis, Intracellular Localization, and Gene Chromosomal Assignment of Mouse 5-Lipoxygenase (*)

  1995cites this paper
• Arachidonate 5-lipoxygenase.

  1995cites this paper
• Interaction of bacteria with mast cells.

  1995cites this paper
• Role of 5-lipoxygenase-activating protein in the regulation of 5-lipoxygenase activity in human neutrophils

  1994cites this paper
• 5-Lipoxygenase: enzyme expression and regulation of activity.

  1994cites this paper
• 5-Lipoxygenase.

  1994cites this paper
• The binding of leukotriene biosynthesis inhibitors to site-directed mutants of human 5-lipoxygenase-activating protein.

  1994cites this paper
• Localization of 5-lipoxygenase to the nucleus of unstimulated rat basophilic leukemia cells.

  1994cites this paper
• 4. Novel aspects of 5-1ipoxygenase biology and inhibitors Role of 5-1ipoxygenase-activating protein in the regulation of 5-1ipoxygenase activity in human neutrophils

  1994cites this paper
• Reversible translocation of 5-lipoxygenase in mast cells upon IgE/antigen stimulation.

  1993cites this paper
• Amino acid residues of 5-lipoxygenase-activating protein critical for the binding of leukotriene biosynthesis inhibitors.

  1993cites this paper
• 5-lipoxygenase-activating protein stimulates the utilization of arachidonic acid by 5-lipoxygenase.

  1993cites this paper
• 5‐lipoxygenase‐activating protein is an arachidonate binding protein

  1993cites this paper
• A23187-induced translocation of 5-lipoxygenase in osteosarcoma cells

  1992cites this paper