Genetics of dermatofibrosarcoma protuberans family of tumors: From ring chromosomes to tyrosine kinase inhibitor treatment

No abstract is available for this paper.

• Publication year

  2003

• Venue

  Genes, Chromosomes and Cancer

• Publication date

  2003-05-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/gcc.10202PMID 12661001
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Pluripotency of mesenchymal stem cells derived from adult marrow

  2007cited by this paper
• A Case of Bednar Tumor

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• Dermatofibrosarcoma Protuberans, Giant Cell Fibroblastoma, and Hybrid Lesions in Children: Clinicopathologic Comparative Analysis of 28 Cases With Molecular Data: A Study From the French Federation of Cancer Centers Sarcoma Group

  2003cited by this paper
• Differential sensitivity to imatinib of 2 patients with metastatic sarcoma arising from dermatofibrosarcoma protuberans

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• Molecular targeting of platelet-derived growth factor B by imatinib mesylate in a patient with metastatic dermatofibrosarcoma protuberans.

  2002cited by this paper
• COL1A1-PDGFB Gene Fusion Demonstrates a Common Histogenetic Origin for Dermatofibrosarcoma Protuberans and Its Granular Cell Variant

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  2002cited by this paper
• COLIA1-PDGFB gene fusion in dermatofibrosarcoma protuberans. molecular analysis of a case with an unusual large marker containing sequences from chromosomes 7, 8, 17, 21, and 22.

  2002cited by this paper
• New members of the platelet-derived growth factor family of mitogens.

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• Concomitant DNA copy number amplification at 17q and 22q in dermatofibrosarcoma protuberans

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• Structural and functional analysis of a chimeric protein COL1A1-PDGFB generated by the translocation t(17;22)(q22;q13.1) in Dermatofibrosarcoma Protuberans (DP)

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• Spectral karyotyping reveals 17;22 fusions in a cytogenetically atypical dermatofibrosarcoma protuberans with a large marker chromosome as a sole abnormality

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• COL1A1-PDGFB fusion transcripts in fibrosarcomatous areas of six dermatofibrosarcomas protuberans.

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• Dermatofibrosarcoma protuberans harboring t(9;22)(q32;q12.2).

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• A progression to dermatofibrosarcoma protuberans with a fibrosarcomatous component: a special reference to the chromosomal aberrations.

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• The dermatofibrosarcoma protuberans-associated collagen type Ialpha1/platelet-derived growth factor (PDGF) B-chain fusion gene generates a transforming protein that is processed to functional PDGF-BB.

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• Pigmented Dermatofibrosarcoma protuberans (Bednář Tumor) Occurring in a Japanese Infant

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• A case of dermatofibrosarcoma protuberans with a ring chromosome 5 and a rearranged chromosome 22 containing amplified COL1A1 and PDGFB sequences.

  1998cited by this paper
• COL1A1-PDGFB fusion in a ring chromosome 4 found in a dermatofibrosarcoma protuberans.

  1998cited by this paper
• COL1A1–PDGFB fusion in a ring chromosome 4 found in a dermatofibrosarcoma protuberans

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• Chemical stability of adapalene and tretinoin when combined with benzoyl peroxide in presence and in absence of visible light and ultraviolet radiation

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• Various regions within the alpha‐helical domain of the COL1A1 gene are fused to the second exon of the PDGFB gene in dermatofibrosarcomas and giant‐cell fibroblastomas

  1998cited by this paper
• Supernumerary ring chromosomes and nuclear blebs in some low-grade malignant soft tissue tumours: atypical lipomatous tumours and dermatofibrosarcoma protuberans

  1998cited by this paper
• Fibrosarcomatous ("high-grade") dermatofibrosarcoma protuberans: clinicopathologic and immunohistochemical study of a series of 41 cases with emphasis on prognostic significance.

  1998cited by this paper
• The atrophic variant of dermatofibrosarcoma protuberans in childhood: a report of six cases

  1998influential reference
• The role of radiation therapy in the management of dermatofibrosarcoma protuberans.

  1998cited by this paper
• Transforming activity of the chimeric sequence formed by the fusion of collagen gene COL1A1 and the platelet derived growth factor b-chain gene in dermatofibrosarcoma protuberans

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• A case of Bednar tumor. Immunohistochemical positivity for CD34.

  1997cited by this paper
• Deregulation of the platelet-derived growth factor β-chain gene via fusion with collagen gene COL1A1 in dermatof ibrosarcoma protuberans and giant-cell fibroblastoma

  1997influential reference
• CD34 and factor-XIIIa immunoreactivity in dermatofibrosarcoma protuberans and dermatofibroma.

  1997cited by this paper
• CGP 57148, a tyrosine kinase inhibitor, inhibits the growth of cells expressing BCR-ABL, TEL-ABL, and TEL-PDGFR fusion proteins.

  1997cited by this paper
• Characterization of platelet-derived growth factor (PDGF) action on a mouse neuroblastoma cell line, NB41, by introduction of an antisense PDGF beta-receptor RNA.

  1997cited by this paper
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  1997cited by this paper
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• Platelet-derived growth factor is an autocrine stimulator for the growth and survival of human esophageal carcinoma cell lines.

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  1996cited by this paper
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  1996cited by this paper
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  1996cited by this paper
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  1996cited by this paper
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  1996cited by this paper
• Ring marker containing 17q and chromosome 22 in a case of dermatofibrosarcoma protuberans.

  1996cited by this paper
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  1996cited by this paper
• Cytogenetic and immunohistochemical evidence that giant cell fibroblastoma is related to dermatofibrosarcoma protuberans

  1996cited by this paper
• Ring 22 chromosomes in dermatofibrosarcoma protuberans are low-level amplifiers of chromosome 17 and 22 sequences.

  1995cited by this paper
• Soft Tissue Tumors

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  1995cited by this paper
• Dermatofibrosarcoma protuberans with 46,XY,t(X;7) abnormality in a child.

  1995cited by this paper
• Ring chromosomes in dermatofibrosarcoma protuberans are composed of interspersed sequences from chromosomes 17 and 22.

  1995cited by this paper
• CD34 positivity in fibrosarcomas which arise in dermatofibrosarcoma protuberans.

  1995cited by this paper
• Case report.

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• [Darier-Ferrand dermatofibrosarcoma in children].

  1995cited by this paper
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  1995cited by this paper
• Aggressive giant cell fibroblastoma with a balanced 17;22 translocation.

  1995cited by this paper
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  1994cited by this paper
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  1994cited by this paper
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  1994cited by this paper
• Dermatofibrosarcoma protuberans.

  1994cited by this paper
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  1994cited by this paper
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  1993cited by this paper
• Ring chromosomes in dermatofibrosarcoma protuberans contain chromosome 17 sequences: fluorescence in situ hybridization.

  1993influential reference
• CD‐34 Is Expressed by a Distinctive Cell Population in Peripheral Nerve, Nerve Sheath Tumors, and Related Lesions

  1993cited by this paper
• Differential expression of factor XIIIa and CD34 in cutaneous mesenchymal tumors

  1993cited by this paper
• Congenital Dermatofibrosarcoma Protuberans

  1993cited by this paper
• Expression of the human progenitor cell antigen CD34 (HPCA-1) distinguishes dermatofibrosarcoma protuberans from fibrous histiocytoma in formalin-fixed, paraffin-embedded tissue.

  1993cited by this paper
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• Dermatofibrosarcoma protuberans recurring as a giant cell fibroblastoma

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• Atypical Gene Rearrangement of the COL1A1::PDGFB Fusion in Dermatofibrosarcoma Protuberans of the Abdominal Wall: A Case Report

  2026cites this paper
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  2025cites this paper
• From skin to pancreas: The unusual path of fibrosarcomatous dermatofibrosarcoma protuberans – A rare case report

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• [Dermatofibrosarcoma protuberans].

  2025cites this paper
• A case report of concurrent dermatofibrosarcoma protuberans and papillary thyroid carcinoma: Diagnostic and therapeutic challenges

  2025cites this paper
• Diagnosis and treatment of dermatofibrosarcoma protuberans. European interdisciplinary guideline - update 2024.

  2025cites this paper
• Treatment of Dermatofibrosarcoma Protuberans With Fixed Mohs Micrographic Surgery: A French Cohort Prospective Study

  2025cites this paper
• Dermatofibrosarcoma Protuberans in Children: Favorable Outcomes Using Wide Local Excision.

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• Clinicopathological and molecular analysis of a dermatofibrosarcoma protuberans with fibrosarcomatous transformation in the breast

  2025cites this paper
• Establishing biomarkers for soft tissue sarcomas

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• A cutaneous spindle cell neoplasm characterized by a COL3A1::PDGFRA fusion

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• Scrotal Dermatofibrosarcoma Protuberans in a Patient with Schizophrenia: A Case Report and Review of the Literature

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• Excision and Reconstruction of Atypical Chest Dermatofibrosarcoma Protuberans Tumor: A Case Report and Literature Review

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• Molecular pathways and therapeutic strategies in dermatofibrosarcoma protuberans (DFSP): unravelling the tumor’s genetic landscape

  2024cites this paper
• Dermatopathology.

  2024cites this paper
• In Vitro Modeling of Recurrent Dermatofibrosarcoma Protuberans: Assessment of 5-Aminolevulinic Acid Photodynamic Therapy Efficacy.

  2024cites this paper
• Multiple primary dermatofibrosarcoma protuberans tumors in a single patient with chromosomal microarray analysis: A case report and review

  2024cites this paper
• Recurrent dermato�brosarcoma protuberans of the breast with rapid growth during pregnancy: a case report

  2023cites this paper
• An update on selected cutaneous (myo) fibroblastic mesenchymal tumors.

  2023cites this paper
• Congenital Atrophic Dermatofibrosarcoma Protuberans: A Case Report and Review of the Literature

  2023influential citation
• Unusual presentation of Giant Dermatofibrosarcoma Protuberans

  2023cites this paper
• New insights about the PDGF/PDGFR signaling pathway as a promising target to develop cancer therapeutic strategies.

  2023cites this paper
• Pediatric dermatofibrosarcoma protuberans: A clinicopathologic and genetic analysis of 66 cases in the largest institution in Southwest China

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• Mammary Spindle Cell Proliferations on Core Needle Biopsy

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• Dermatofibrosarcoma Protuberans: A Surgeon's Enigma

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• Dermatofibrosarcoma protuberans of the hand in a young child: A case report and review of literature

  2023cites this paper
• Unraveling intratumoral complexity in metastatic dermatofibrosarcoma protuberans through single-cell RNA sequencing analysis

  2023cites this paper
• Skin Cancer: Back to Basics

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• Surgical management of dermatofibrosarcoma protuberans

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• Dermatofibrosarcoma protuberans of the scalp: Surgical management in a multicentric series of 11 cases and systematic review of the literature.

  2023cites this paper
• Outcome of Surgical Management of Dermatofibrosarcoma Protuberance: A Single-Institution Multidisciplinary Approach

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• Targeted therapy and immunotherapy for orbital and periorbital tumors: a major review

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• Review of dermatofibrosarcoma protuberans.

  2022cites this paper
• Myxoid Dermatofibrosarcoma Protuberans of the Scrotum: Rare Tumor in an Uncommon Location

  2022cites this paper
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• DermatoFibroSarcoma Protuberans: A case report of a complete cure

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• Novel TNC-PDGFD fusion in fibrosarcomatous dermatofibrosarcoma protuberans: a case report

  2021cites this paper
• Risk factors related to postoperative recurrence of dermatofibrosarcoma protuberans: A retrospective study and literature review

  2021cites this paper
• A case of dermatofibrosarcoma protuberans with neurofibromatous change

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• Neurofibrosarcoma Revisited: An Institutional Case Series of Uterine Sarcomas Harboring Kinase-related Fusions With Report of a Novel FGFR1-TACC1 Fusion.

  2021cites this paper
• PDGFB RNA in situ hybridization for the diagnosis of dermatofibrosarcoma protuberans

  2021cites this paper
• Molecular profiling of gene fusions in soft tissue sarcomas by Ion AmpliSeqTM: a study of 35 cases

  2021cites this paper
• The Extracellular Matrix in Soft Tissue Sarcomas: Pathobiology and Cellular Signalling

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• Prevalence of dermatofibrosarcoma protuberans in Saudi Arabia over 24 years.

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• Long-Term Outcome of Neoadjuvant Tyrosine Kinase Inhibitors Followed by Complete Surgery in Locally Advanced Dermatofibrosarcoma Protuberans

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• Dermatofibrosarcoma protuberans with platelet‐derived growth factor‐D rearrangement; two cases with morphologically distinct presentations

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• A Novel COL1A1-CAMTA1 Rearrangement in Cranial Fasciitis

  2020cites this paper
• Dermatofibrosarcoma protuberans with fibrosarcomatous transformation: A tale of unbridled expansion

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• Dermatofibrosarcoma Protuberans: Update on the Diagnosis and Treatment

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• A novel aberration of COL1A1‐PDGFB fusion as an insertion in chromosome 15 in one case of dermatofibrosarcoma protuberans involving a rare location

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• Giant Cell Fibroblastoma, Soft Tissue

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  2019influential citation
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• "Hey!- Whatever Happened to Hemangiopericytoma and Fibrosarcoma?" An Update on Selected Conceptual Advances in Soft Tissue Pathology Which Have Occurred Over the Past 50 Years.

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• The efficacy of Mohs micrographic surgery over the traditional wide local excision surgery in the cure of dermatofibrosarcoma protuberans

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• A novel MAP3K7CL‐ERG fusion in a molecularly confirmed case of dermatofibrosarcoma protuberans with fibrosarcomatous transformation

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• Review of the medical literature and assessment of current utilization patterns regarding the use of two common fluorescence in situ hybridization assays in the diagnosis of dermatofibrosarcoma protuberans and clear cell sarcoma

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