Intravenous nicorandil in conjunction with coronary reperfusion therapy is associated with better clinical and functional outcomes in patients with acute myocardial infarction.

No abstract is available for this paper.

• Publication year

  2003

• Venue

  Circulation Journal

• Publication date

  2003-03-20

• Fields of study

  Medicine

• Identifiers
  DOI 10.1253/CIRCJ.67.295PMID 12655158
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  1996cited by this paper
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  1995cited by this paper
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  1994cited by this paper
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  1993cited by this paper
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  1992cited by this paper
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  1990cited by this paper
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  1990cited by this paper
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  1987cited by this paper
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  1987cited by this paper
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  1987cited by this paper
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  1986cited by this paper
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  1986cited by this paper
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  1986cited by this paper
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  1983cited by this paper

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