Cytokine Profiles for Peripheral Blood Lymphocytes from Patients with Active Pulmonary Tuberculosis and Healthy Household Contacts in Response to the 30-Kilodalton Antigen ofMycobacterium tuberculosis

No abstract is available for this paper.

• Publication year

  1998

• Venue

  Infection and Immunity

• Publication date

  1998-01-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/IAI.66.1.176-180.1998PMID 9423855PMCID PMC107874
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  1997cited by this paper
• T cell-derived IL-10 antagonizes macrophage function in mycobacterial infection.

  1997cited by this paper
• Immunogenicity and protective efficacy of a tuberculosis DNA vaccine

  1996influential reference
• T-cell cytokine responses in human infection with Mycobacterium tuberculosis

  1995cited by this paper
• Human T-cell responses to secreted antigen fractions of Mycobacterium tuberculosis

  1995cited by this paper
• Mapping of T cell epitopes of the 30-kDa alpha antigen of Mycobacterium bovis strain bacillus Calmette-Guérin in purified protein derivative (PPD)-positive individuals.

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• Protective immunity against tuberculosis induced by vaccination with major extracellular proteins of Mycobacterium tuberculosis.

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• Mapping of TH1 helper T-cell epitopes on major secreted mycobacterial antigen 85A in mice infected with live Mycobacterium bovis BCG

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  1994influential reference
• Evidence for a Th1-like bronchoalveolar T-cell subset and predominance of interferon-gamma gene activation in pulmonary tuberculosis.

  1994cited by this paper
• Cytokine production at the site of disease in human tuberculosis

  1993cited by this paper
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• T cell response to Mycobacterium tuberculosis.

  1993cited by this paper
• Protein antigens of mycobacteria studied by quantitative immunologic techniques.

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• Human immune response to Mycobacterium tuberculosis antigens

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• Defining protective responses to pathogens: cytokine profiles in leprosy lesions.

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• Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.

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