Translation of CGA codon repeats in yeast involves quality control components and ribosomal protein L1

Daniel P Letzring,Andrew S. Wolf,C. E. Brule,E. Grayhack

Published 2013 in RNA: A publication of the RNA Society

ABSTRACT

It has been known that translation of CGA codon repeats in budding yeast is inefficient. This paper examines the reasons for inefficient translation, and the findings indicate unexpected complexity revealing that inhibition of translation by CGA codons results from at least two independent defects.

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