Biosynthesis of isoprenoids in higher plant chloroplasts proceeds via a mevalonate‐independent pathway

Isopentenyl diphosphate (IPP) is the biological C5 precursor of isoprenoids. By labeling experiments using [1‐13C]glucose, higher plants were shown to possess two distinct biosynthetic routes for IPP biosynthesis: while the cytoplasmic sterols were formed via the acetate/mevalonate pathway, the chloroplast‐bound isoprenoids (β‐carotene, lutein, prenyl chains of chlorophylls and plastoquinone‐9) were synthesized via a novel IPP biosynthesis pathway (glyceraldehyde phosphate/pyruvate pathway) which was first found in eubacteria and a green alga. The dichotomy in isoprenoid biosynthesis in higher plants allows a reasonable interpretation of previous odd and inconclusive results concerning the biosynthesis of chloroplast isoprenoids, which so far had mainly been interpreted in the frame of models using compartmentation of the mevalonate pathway.

• Publication year

  1997

• Venue

  FEBS Letters

• Publication date

  1997-01-06

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1016/S0014-5793(96)01404-4PMID 9009212
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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