Induction of lithostathine/reg mRNA expression by serum from rats with acute pancreatitis and cytokines in pancreatic acinar AR-42J cells.

No abstract is available for this paper.

• Publication year

  1996

• Venue

  Archives of Biochemistry and Biophysics

• Publication date

  1996-06-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1006/ABBI.1996.0234PMID 8651687
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The rat genes encoding the pancreatitis-associated proteins I, II and III (Pap1, Pap2, Pap3), and the lithostathin/pancreatic stone protein/regeneration protein (Reg) colocalize at 4q33-->q34.

  1996cited by this paper
• Cloning, expression and chromosomal localization of the rat pancreatitis-associated protein III gene.

  1995cited by this paper
• Serum from rats with acute pancreatitis induces expression of the PAP mRNA in the pancreatic acinar cell line AR-42J.

  1994cited by this paper
• Cytokines, endotoxin, and glucocorticoids regulate the expression of inducible nitric oxide synthase in hepatocytes.

  1993cited by this paper
• Up-regulation by tumor necrosis factor alpha of intercellular adhesion molecule 1 expression and function in synovial fibroblasts and its inhibition by glucocorticoids.

  1993cited by this paper
• Structural organization of the gene encoding the rat pancreatitis-associated protein. Analysis of its evolutionary history reveals an ancient divergence from the other carbohydrate-recognition domain-containing genes.

  1993cited by this paper
• Identification of a second rat pancreatitis-associated protein. Messenger RNA cloning, gene structure, and expression during acute pancreatitis.

  1993cited by this paper
• Cytoplasmic phospholipase A2 activity and gene expression are stimulated by tumor necrosis factor: dexamethasone blocks the induced synthesis.

  1993cited by this paper
• Lithostathine, an Inhibitor of CaCO3, Crystal Growth in Pancreatic Juice, Induces Bacterial Aggregation

  1993cited by this paper
• Rapid PCR cloning and sequence determination of the rat lithostathine gene.

  1993cited by this paper
• Regulation of C4b-binding protein gene expression by the acute-phase mediators tumor necrosis factor-alpha, interleukin-6, and interleukin-1.

  1992cited by this paper
• Messenger RNA sequence and expression of rat pancreatitis-associated protein, a lectin-related protein overexpressed during acute experimental pancreatitis.

  1991cited by this paper
• Gene regulation by interleukin 6.

  1991cited by this paper
• Purification and cloning of interferon-stimulated gene factor 2 (ISGF2): ISGF2 (IRF-1) can bind to the promoters of both beta interferon- and interferon-stimulated genes but is not a primary transcriptional activator of either

  1990cited by this paper
• Isolation and characterization of eight tumor necrosis factor-induced gene sequences from human fibroblasts

  1990cited by this paper
• Action of recombinant human interleukin 6, interleukin 1 beta and tumor necrosis factor alpha on the mRNA induction of acute-phase proteins.

  1988cited by this paper
• Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction.

  1987cited by this paper
• Structure of a family of rat amylase genes

  1980cited by this paper
• The influence of glucagon on acute experimental pancreatitis in the rat.

  1974cited by this paper

• Diagnostic Performance of Point-of-Care Immunoassay Measurements of Pancreatic Stone Protein for Sepsis Detection in ICU Patients: A Prospective, Multicenter, Biomarker-Blinded Study.

  2026cites this paper
• Examining pancreatic stone protein response in ICU-acquired bloodstream infections: a matched event analysis

  2024cites this paper
• Development and application of a novel aldehyde nanoparticle-based amplified luminescent proximity homogeneous assay for rapid quantitation of pancreatic stone protein.

  2022cites this paper
• Pancreatic Stone Protein: Review of a New Biomarker in Sepsis

  2022cites this paper
• Mini Review ISLET Neogenesis in Man Without the Need for Transplants

  2021cites this paper
• The Potential Role of REG Family Proteins in Inflammatory and Inflammation-Associated Diseases of the Gastrointestinal Tract

  2021cites this paper
• Four Decades After the Discovery of Regenerating Islet-Derived (Reg) Proteins: Current Understanding and Challenges

  2019cites this paper
• MicroRNA-7 directly targets Reg1 in pancreatic cells.

  2019cites this paper
• of Diabetes and Treatment Islet Neogenesis Therapy from Endogenous Pancreatic Stem Cells without Transplantation: Will Type 1 and Type 2 Diabetes Soon be Diseases of the Past?

  2017cites this paper
• Effect of resveratrol on cancer progression through the REG Ⅲ expression pathway in head and neck cancer cells.

  2016cites this paper
• Microarray analysis of pancreatic gene expression during biotin repletion in biotin-deficient rats.

  2015cites this paper
• Distinct Cell Clusters Touching Islet Cells Induce Islet Cell Replication in Association with Over-Expression of Regenerating Gene (REG) Protein in Fulminant Type 1 Diabetes

  2014cites this paper
• Transcriptional activation of Reg2 and Reg3β genes by glucocorticoids and interleukin-6 in pancreatic acinar and islet cells.

  2013cites this paper
• Reg proteins and their roles in inflammation and cancer of the human digestive system.

  2013cites this paper
• PSP/reg: a new stone in sepsis biomarkers?

  2012cites this paper
• Distribution of lithostathine in the mouse lemur brain with aging and Alzheimer’s-like pathology.

  2012cites this paper
• Regenerating proteins and their expression, regulation, and signaling

  2012cites this paper
• MECHANISMS OF ACTION OF ISLET NEOGENESIS ASSOCIATED PROTEIN 1 ( INGAP ) : COMPARISON OF THE FULL-LENGTH RECOMBINANT PROTEIN AND 2 A BIO-ACTIVE PEPTIDE 3 4

  2012cites this paper
• Distribution of lithostathine in the mouse lemur brain with aging and Alzheimer's-like pathology.

  2012cites this paper
• Mechanisms of action of islet neogenesis-associated protein: comparison of the full-length recombinant protein and a bioactive peptide.

  2012cites this paper
• Regenerating gene (REG) 1 alpha promotes pannus progression in patients with rheumatoid arthritis

  2012cites this paper
• Regenerating (Reg) Gene Family

  2012cites this paper
• Pancreatic stone protein: a marker of organ failure and outcome in ventilator-associated pneumonia.

  2011cites this paper
• Adjuvant Immunotherapy Increases b Cell Regenerative Factor Regeneration Gene 2 in the Pancreas of Diabetic Mice

  2010cites this paper
• Adjuvant Immunotherapy Increases β Cell Regenerative Factor Reg2 in the Pancreas of Diabetic Mice

  2010cites this paper
• PAP1 signaling involves MAPK signal transduction

  2009cites this paper
• Pancreatic stone protein is highly increased during posttraumatic sepsis and activates neutrophil granulocytes*

  2009cites this paper
• Involvement of REG Iα protein in the regeneration of ductal epithelial cells in the minor salivary glands of patients with Sjögren's syndrome

  2009cites this paper
• REG Proteins and Other Growth Factors in Gastric Cancer

  2009cites this paper
• The identification and sequence analysis of a new Reg3gamma and Reg2 in the Syrian golden hamster.

  2007cites this paper
• Reg-II is an exocrine pancreas injury-response product that is up-regulated by keratin absence or mutation.

  2007influential citation
• Expression of the REG IV gene in ulcerative colitis

  2007cites this paper
• Development of an in vitro pancreatic tissue model to study regulation of islet neogenesis associated protein expression.

  2006influential citation
• Dexamethasone mediates protection against acute pancreatitis via upregulation of pancreatitis-associated proteins.

  2006influential citation
• Pancreatic regenerating protein (reg I) and reg I receptor mRNA are upregulated in rat pancreas after induction of acute pancreatitis.

  2006cites this paper
• The multifunctional family of secreted proteins containing a C-type lectin-like domain linked to a short N-terminal peptide.

  2005cites this paper
• Possible role of REG Iα protein in ulcerative colitis and colitic cancer

  2005cites this paper
• REG Ialpha protein may function as a trophic and/or anti-apoptotic factor in the development of gastric cancer.

  2005cites this paper
• Reg protein is a unique growth factor of gastric mucosal cells

  2004cites this paper
• Coordinate regulation of PSP/reg and PAP isoforms as a family of secretory stress proteins in an animal model of chronic pancreatitis.

  2004cites this paper
• Mist1 is necessary for the establishment of granule organization in serous exocrine cells of the gastrointestinal tract.

  2004cites this paper
• Control of expression of the lectin-like protein Reg-1 by gastrin: role of the Rho family GTPase RhoA and a C-rich promoter element.

  2004cites this paper
• Effects of Helicobacter pylori Infection on the Link between Regenerating Gene Expression and Serum Gastrin Levels in Mongolian Gerbils

  2003cites this paper
• Insights into the Mechanisms of Gastric Adaptation to Aspirin-Induced Injury: A Role for Regenerating Protein but Not Trefoil Peptides

  2003cites this paper
• Xanthine oxidase‐derived oxygen radicals play significant roles in the development of chronic pancreatitis in WBN/Kob rats

  2002cites this paper
• Biomarker discovery in urine by proteomics.

  2002cites this paper
• Comparison of leptin- and interleukin-6-regulated expression of the rPAP gene family: evidence for differential co-regulatory signals.

  2002cites this paper
• The bHLH transcription factor Mist1 is required to maintain exocrine pancreas cell organization and acinar cell identity

  2001cites this paper
• Expression of Tumor Necrosis Factor-&agr;, Interleukin-6, and Interferon-&ggr; in Spontaneous Chronic Pancreatitis in the WBN/Kob Rat

  2001cites this paper
• Pancreatitis‐associated protein‐I mRNA expression in mouse pancreas is upregulated by lipopolysaccharide independent of cerulein‐pancreatitis

  2001cites this paper
• Expression of tumor necrosis factor-alpha, interleukin-6, and interferon-gamma in spontaneous chronic pancreatitis in the WBN/Kob rat.

  2001cites this paper
• Lithostathine and pancreatitis-associated protein are involved in the very early stages of Alzheimer's disease.

  2001cites this paper
• Diabetes and tumor formation in transgenic mice expressing Reg I.

  2000cites this paper
• Neutrophil chemoattractant 2 beta regulates expression of the Reg gene in injured gastric mucosa in rats.

  2000cites this paper
• Biophysical Characterization of Lithostathine

  1999cites this paper
• Immunoreactive pancreatic Reg protein in sera from cystic fibrosis patients with and without pancreatic insufficiency

  1999cites this paper
• Apoptosis and remodelling of beta cells by paracrine interferon-γ without insulitis in transgenic mice

  1999cites this paper
• Expression of pancreatitis-associated protein (PAP) mRNA in gastrointestinal cancers

  1998cites this paper
• The role of cytokines in the pathogenesis of acute pancreatitis.

  1998cites this paper
• The pancreatitis-associated protein is induced by free radicals in AR4-2J cells and confers cell resistance to apoptosis.

  1998cites this paper
• Specific reg II gene overexpression in the non‐obese diabetic mouse pancreas during active diabetogenesis

  1997cites this paper