Mitochondrial biogenesis and fragmentation as regulators of protein degradation in striated muscles.

No abstract is available for this paper.

• Publication year

  2013

• Venue

  Journal of Molecular and Cellular Cardiology

• Publication date

  2013-02-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.yjmcc.2012.08.001PMID 22902321
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Proteolytic control of mitochondrial function and morphogenesis.

  2013cited by this paper
• Mitochondrial dynamics in heart disease.

  2013cited by this paper
• Spatially distinct mitochondrial populations exhibit different mitofilin levels

  2012cited by this paper
• Microtubule-associated Protein 1 Light Chain 3 (LC3) Interacts with Bnip3 Protein to Selectively Remove Endoplasmic Reticulum and Mitochondria via Autophagy*

  2012cited by this paper
• Mitochondrial DNA That Escapes from Autophagy Causes Inflammation and Heart Failure

  2012cited by this paper
• AMPK promotes skeletal muscle autophagy through activation of forkhead FoxO3a and interaction with Ulk1

  2012cited by this paper
• Central Role of Mitofusin 2 in Autophagosome-Lysosome Fusion in Cardiomyocytes*

  2012cited by this paper
• The effects of aging, physical training, and a single bout of exercise on mitochondrial protein expression in human skeletal muscle.

  2012cited by this paper
• Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis

  2012cited by this paper
• PTEN-inducible kinase 1 (PINK1)/Park6 is indispensable for normal heart function

  2011cited by this paper
• Mitochondrial Fusion is Essential for Organelle Function and Cardiac Homeostasis

  2011cited by this paper
• Unopposed mitochondrial fission leads to severe lifespan shortening

  2011cited by this paper
• During autophagy mitochondria elongate, are spared from degradation and sustain cell viability

  2011cited by this paper
• Cardiac mitochondria in heart failure: normal cardiolipin profile and increased threonine phosphorylation of complex IV.

  2011cited by this paper
• Broad activation of the ubiquitin–proteasome system by Parkin is critical for mitophagy

  2011cited by this paper
• OXPHOS susceptibility to oxidative modifications: the role of heart mitochondrial subcellular location.

  2011cited by this paper
• Physical exercise stimulates autophagy in normal skeletal muscles but is detrimental for collagen VI-deficient muscles

  2011cited by this paper
• MiD49 and MiD51, new components of the mitochondrial fission machinery

  2011cited by this paper
• Molecular mechanisms and physiologic functions of mitochondrial dynamics.

  2011cited by this paper
• Tubular network formation protects mitochondria from autophagosomal degradation during nutrient starvation

  2011cited by this paper
• Human MIEF1 recruits Drp1 to mitochondrial outer membranes and promotes mitochondrial fusion rather than fission

  2011cited by this paper
• FoxO3 induces reversible cardiac atrophy and autophagy in a transgenic mouse model.

  2011cited by this paper
• Parkin Mediates Proteasome-dependent Protein Degradation and Rupture of the Outer Mitochondrial Membrane*♦

  2011cited by this paper
• Mitochondrial autophagy by Bnip3 involves Drp1-mediated mitochondrial fission and recruitment of Parkin in cardiac myocytes.

  2011cited by this paper
• PGC-1α-mediated adaptations in skeletal muscle

  2010cited by this paper
• Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cells

  2010cited by this paper
• Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy.

  2010cited by this paper
• p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both

  2010cited by this paper
• Mitochondrial fusion and fission in cell life and death

  2010cited by this paper
• Inhibition of autophagy in the heart induces age-related cardiomyopathy

  2010cited by this paper
• Mitochondrial fusion is required for mtDNA stability in skeletal muscle and tolerance of mtDNA mutations.

  2010cited by this paper
• Autophagy is defective in collagen VI muscular dystrophies, and its reactivation rescues myofiber degeneration

  2010cited by this paper
• Mitochondrial fission and remodelling contributes to muscle atrophy

  2010influential reference
• Mitochondrial Pruning by Nix and BNip3: An Essential Function for Cardiac-Expressed Death Factors

  2010cited by this paper
• Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin

  2010cited by this paper
• Mitochondria supply membranes for autophagosome biogenesis during starvation.

  2010cited by this paper
• Nix is a selective autophagy receptor for mitochondrial clearance

  2010cited by this paper
• Peroxisome Proliferator-activated Receptor γ Coactivator 1α or 1β Overexpression Inhibits Muscle Protein Degradation, Induction of Ubiquitin Ligases, and Disuse Atrophy*

  2010influential reference
• Loss of PINK1 Function Promotes Mitophagy through Effects on Oxidative Stress and Mitochondrial Fission*

  2009cited by this paper
• Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice

  2009cited by this paper
• The dynamin-related GTPase Drp1 is required for embryonic and brain development in mice

  2009cited by this paper
• Mitofusin-2 regulates mitochondrial and endoplasmic reticulum morphology and tethering: the role of Ras.

  2009cited by this paper
• Increased muscle PGC-1α expression protects from sarcopenia and metabolic disease during aging

  2009cited by this paper
• Mitochondrial OPA1, apoptosis, and heart failure.

  2009cited by this paper
• Autophagy is required to maintain muscle mass.

  2009cited by this paper
• Mitochondrial fusion and division: Regulation and role in cell viability.

  2009cited by this paper
• Mitochondrial function and apoptotic susceptibility in aging skeletal muscle

  2008cited by this paper
• Signaling in muscle atrophy and hypertrophy.

  2008influential reference
• Suppression of autophagy in skeletal muscle uncovers the accumulation of ubiquitinated proteins and their potential role in muscle damage in Pompe disease.

  2008cited by this paper
• CaM kinase Iα–induced phosphorylation of Drp1 regulates mitochondrial morphology

  2008cited by this paper
• Hax1-mediated processing of HtrA2 by Parl allows survival of lymphocytes and neurons

  2008cited by this paper
• Essential role for Nix in autophagic maturation of erythroid cells

  2008cited by this paper
• Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

  2008cited by this paper
• Transcriptional coactivators PGC-1alpha and PGC-lbeta control overlapping programs required for perinatal maturation of the heart.

  2008cited by this paper
• OPA1 mutations induce mitochondrial DNA instability and optic atrophy 'plus' phenotypes.

  2008cited by this paper
• Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance.

  2008cited by this paper
• Dephosphorylation by calcineurin regulates translocation of Drp1 to mitochondria

  2008cited by this paper
• Skeletal muscle is a primary target of SOD1G93A-mediated toxicity.

  2008cited by this paper
• Activity-dependent signaling pathways controlling muscle diversity and plasticity.

  2007cited by this paper
• OPA1 processing controls mitochondrial fusion and is regulated by mRNA splicing, membrane potential, and Yme1L

  2007cited by this paper
• The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress

  2007cited by this paper
• Skeletal muscle remodeling

  2007cited by this paper
• Reversible phosphorylation of Drp1 by cyclic AMP‐dependent protein kinase and calcineurin regulates mitochondrial fission and cell death

  2007cited by this paper
• Therapeutic approaches for muscle wasting disorders.

  2007cited by this paper
• Mitotic Phosphorylation of Dynamin-related GTPase Drp1 Participates in Mitochondrial Fission*

  2007cited by this paper
• The Energy Sensor AMP-activated Protein Kinase Directly Regulates the Mammalian FOXO3 Transcription Factor*

  2007cited by this paper
• Response to myocardial ischemia/reperfusion injury involves Bnip3 and autophagy

  2007cited by this paper
• A lethal defect of mitochondrial and peroxisomal fission.

  2007cited by this paper
• FoxO3 controls autophagy in skeletal muscle in vivo.

  2007cited by this paper
• PGC-1α protects skeletal muscle from atrophy by suppressing FoxO3 action and atrophy-specific gene transcription

  2006cited by this paper
• Structure of cristae in cardiac mitochondria of aged rat.

  2006cited by this paper
• OPA1 controls apoptotic cristae remodeling independently from mitochondrial fusion.

  2006cited by this paper
• Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin

  2006cited by this paper
• Mitochondrial rhomboid PARL regulates cytochrome c release during apoptosis via OPA1-dependent cristae remodeling.

  2006cited by this paper
• Regulation of mitochondrial morphology through proteolytic cleavage of OPA1

  2006cited by this paper
• Denervation in murine fast-twitch muscle: short-term physiological changes and temporal expression profiling.

  2006cited by this paper
• Mitochondrial dynamics and aging: Mitochondrial interaction preventing individuals from expression of respiratory deficiency caused by mutant mtDNA.

  2006cited by this paper
• Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin

  2006cited by this paper
• Burn injury causes mitochondrial dysfunction in skeletal muscle.

  2005cited by this paper
• Activated Mitofusin 2 Signals Mitochondrial Fusion, Interferes with Bax Activation, and Reduces Susceptibility to Radical Induced Depolarization*[boxs]

  2005cited by this paper
• The FOXO3a Transcription Factor Regulates Cardiac Myocyte Size Downstream of AKT Signaling*

  2005cited by this paper
• Skeletal Muscle FOXO1 (FKHR) Transgenic Mice Have Less Skeletal Muscle Mass, Down-regulated Type I (Slow Twitch/Red Muscle) Fiber Genes, and Impaired Glycemic Control*[boxs]

  2004cited by this paper
• Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression

  2004cited by this paper
• Neuroprotective Role of the Reaper-Related Serine Protease HtrA2/Omi Revealed by Targeted Deletion in Mice

  2004cited by this paper
• Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy.

  2004cited by this paper
• Mitofusin 1 and 2 play distinct roles in mitochondrial fusion reactions via GTPase activity

  2004cited by this paper
• OPA1 requires mitofusin 1 to promote mitochondrial fusion.

  2004cited by this paper
• Mutations in the mitochondrial GTPase mitofusin 2 cause Charcot-Marie-Tooth neuropathy type 2A

  2004cited by this paper
• Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1

  2003cited by this paper
• Coordination of p300-mediated chromatin remodeling and TRAP/mediator function through coactivator PGC-1alpha.

  2003cited by this paper
• Loss of Omi mitochondrial protease activity causes the neuromuscular disorder of mnd2 mutant mice

  2003cited by this paper
• The Mitochondrial Protein hFis1 Regulates Mitochondrial Fission in Mammalian Cells through an Interaction with the Dynamin-Like Protein DLP1

  2003cited by this paper
• Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibres.

  2002cited by this paper
• Transcriptional co-activator PGC-1α drives the formation of slow-twitch muscle fibres

  2002cited by this paper
• Inducible Expression of BNIP3 Provokes Mitochondrial Defects and Hypoxia-Mediated Cell Death of Ventricular Myocytes

  2002cited by this paper
• Mitochondrial death protein Nix is induced in cardiac hypertrophy and triggers apoptotic cardiomyopathy

  2002cited by this paper
• The mitochondrial permeability transition initiates autophagy in rat hepatocytes

  2001cited by this paper
• Identification of Ubiquitin Ligases Required for Skeletal Muscle Atrophy

  2001cited by this paper
• Dynamin-related protein Drp1 is required for mitochondrial division in mammalian cells.

  2001cited by this paper
• C. elegans dynamin-related protein DRP-1 controls severing of the mitochondrial outer membrane.

  1999cited by this paper

• Therapeutic ultrasound and passive mobilisation improve motor function and reduce inflammation in skeletal muscle of immobilised Wistar rats

  2025cites this paper
• Irisin Increases Sirtuin 1 to Improve Glucocorticoid-Induced Sarcopenia and Mitochondrial Dysfunction

  2025cites this paper
• Modulation of muscle anabolism and gut microbiota by Polyporus umbellatus extract attenuates dexamethasone-induced muscle atrophy

  2025cites this paper
• Reorganization of Mitochondrial Function and Architecture in Response to Plant‐Derived Alkaloids: Anatabine, Anabasine, and Nicotine, Investigated in SH‐SY5Y Cells and in a Cellular Model of Parkinson's Disease

  2025cites this paper
• Cisplatin‐Induced Muscle Wasting and Atrophy: Molecular Mechanism and Potential Therapeutic Interventions

  2025cites this paper
• The role of cell death in the physiological and pathological processes of skeletal muscle

  2025cites this paper
• Inhibitory regulation of FoxO1 in PPARδ expression drives mitochondria dysfunction and insulin resistance.

  2024cites this paper
• Moderate-Intensity Exercise Enhances Mitochondrial Biogenesis Markers in the Skeletal Muscle of a Mouse Model Affected by Diet-Induced Obesity

  2024cites this paper
• Intracellular to Interorgan Mitochondrial Communication in Striated Muscle in Health and Disease

  2023cites this paper
• Effects of voluntary running on the skeletal muscle of rats with pulmonary artery hypertension

  2023cites this paper
• Castor Oil Plant (Ricinus communis L.) Leaves Improve Dexamethasone-Induced Muscle Atrophy via Nrf2 Activation

  2022cites this paper
• Long-Lasting Impairments in Quadriceps Mitochondrial Health, Muscle Size, and Phenotypic Composition Are Present After Non-invasive Anterior Cruciate Ligament Injury

  2022cites this paper
• Quercetin Improved Muscle Mass and Mitochondrial Content in a Murine Model of Cancer and Chemotherapy-Induced Cachexia

  2022cites this paper
• Minimal adaptation of the molecular regulators of mitochondrial dynamics in response to unilateral limb immobilisation and retraining in middle-aged men

  2022cites this paper
• Gomisin G improves muscle strength by enhancing mitochondrial biogenesis and function in disuse muscle atrophic mice.

  2022cites this paper
• Redox signaling regulates skeletal muscle remodeling in response to exercise and prolonged inactivity

  2022cites this paper
• Quantitative intravital imaging in zebrafish reveals in vivo dynamics of physiological-stress-induced mitophagy

  2021cites this paper
• 20(s)-ginseonside-Rg3 modulation of AMPK/FoxO3 signaling to attenuate mitochondrial dysfunction in a dexamethasone-injured C2C12 myotube-based model of skeletal atrophy in vitro

  2021cites this paper
• Resistance training mitigates hepato-cardiac changes and muscle mitochondrial protein reductions in rats with diet-induced obesity

  2021cites this paper
• Growth hormone secretagogue receptor‐1a mediates ghrelin's effects on attenuating tumour‐induced loss of muscle strength but not muscle mass

  2021cites this paper
• FGF21: a promising therapeutic agent for alcoholic cardiomyopathy?†

  2021cites this paper
• Astaxanthin Prevents Atrophy in Slow Muscle Fibers by Inhibiting Mitochondrial Reactive Oxygen Species via a Mitochondria-Mediated Apoptosis Pathway

  2021cites this paper
• Live imaging of reporter zebrafish reveals dynamics and molecular basis of physiological-stress induced mitophagy

  2020cites this paper
• Astaxanthin Prevents Atrophy in Slow Fiber Muscles by Inhibiting Mitochondrial Reactive Oxygen Species Via a Mitochondria-Mediated Apoptosis Pathway

  2020cites this paper
• The connection between the dynamic remodeling of the mitochondrial network and the regulation of muscle mass

  2020cites this paper
• Sex Differences in Cancer Cachexia

  2020cites this paper
• Mitophagy and Mitochondria Biogenesis Are Differentially Induced in Rat Skeletal Muscles during Immobilization and/or Remobilization

  2020cites this paper
• Redox Control of Proteolysis During Inactivity-Induced Skeletal Muscle Atrophy

  2020cites this paper
• Mitochondrial Dysfunction in Skeletal Muscle Pathologies.

  2019cites this paper
• Myricanol rescues dexamethasone‐induced muscle dysfunction via a sirtuin 1‐dependent mechanism

  2019influential citation
• Small‐molecule‐mediated chemical knock‐down of MuRF1/MuRF2 and attenuation of diaphragm dysfunction in chronic heart failure

  2019cites this paper
• Autophagy Exacerbates Muscle Wasting in Cancer Cachexia and Impairs Mitochondrial Function.

  2019cites this paper
• DRP1-mediated mitochondrial shape controls calcium homeostasis and muscle mass

  2019cites this paper
• Myricanol modulates skeletal muscle–adipose tissue crosstalk to alleviate high‐fat diet‐induced obesity and insulin resistance

  2019cites this paper
• 1α,25-dihydroxyvitamin D3 mitigates cancer cell mediated mitochondrial dysfunction in human skeletal muscle cells

  2018cites this paper
• The effect of melatonin treatment on doxorubicin-induced skeletal muscle atrophy within a cancer model

  2018cites this paper
• Muscle wasting in the presence of disease, why is it so variable?

  2018cites this paper
• Mitochondria in Skeletal Muscle Health, Aging and Diseases

  2017cites this paper
• The 2015 ESPEN Sir David Cuthbertson lecture: Inflammation as the driving force of muscle wasting in cancer.

  2017cites this paper
• Signalling mechanisms underlying doxorubicin and Nox2 NADPH oxidase‐induced cardiomyopathy: involvement of mitofusin‐2

  2017cites this paper
• Mitochondria and mitochondria-induced signalling molecules as longevity determinants.

  2017cites this paper
• Muscle mitochondria dysfunctions in Spinal and Bulbar Muscular Atrophy

  2016cites this paper
• Developmental Programming and Life Course Regulation of Skeletal Muscle Inflammation and Oxidative Function

  2016cites this paper
• Mitochondrial Quality Control and Muscle Mass Maintenance

  2016cites this paper
• The emerging role of skeletal muscle oxidative metabolism as a biological target and cellular regulator of cancer-induced muscle wasting.

  2016cites this paper
• Ventilator-induced diaphragmatic dysfunction: what have we learned?

  2016cites this paper
• Mitochondrial Dysfunction Launches Dexamethasone-Induced Skeletal Muscle Atrophy via AMPK/FOXO3 Signaling.

  2016cites this paper
• The Emerging Role of Skeletal Muscle Metabolism as a Biological Target and Cellular Regulator of Cancer-Induced Muscle Wasting

  2016cites this paper
• Cardiac Metabolism in Perspective.

  2016cites this paper
• Autophagy is induced in the skeletal muscle of cachectic cancer patients

  2016cites this paper
• Signaling pathways underlying skeletal muscle wasting in experimental pulmonary arterial hypertension.

  2015cites this paper
• Muscle wasting in cancer: the role of mitochondria

  2015cites this paper
• Effect of limb demand ischemia on autophagy and morphology in mice.

  2015cites this paper
• Activation of AMP-activated protein kinase induce expression of FoxO1, FoxO3a, and myostatin after exercise-induced muscle damage.

  2015cites this paper
• Cachexia and sarcopenia: mechanisms and potential targets for intervention.

  2015cites this paper
• Mitochondrial plasticity in cancer-related muscle wasting: potential approaches for its management

  2015cites this paper
• Solving mitochondrial mysteries.

  2015cites this paper
• Protein phosphatase 2C-alpha knockdown reduces angiotensin II-mediated skeletal muscle wasting via restoration of mitochondrial recycling and function

  2014influential citation
• PGC-1α buffers ROS-mediated removal of mitochondria during myogenesis

  2014cites this paper
• Mitochondrial Dysregulation in Skeletal Muscle from Patients Diagnosed with Alzheimer's Disease and Sporadic Inclusion Body Myositis

  2014cites this paper
• Skeletal muscle mitochondria: a major player in exercise, health and disease.

  2014cites this paper
• Integrating mitochondrial organization and dynamics with cellular architecture.

  2014cites this paper
• Metabolic and transcriptional responses of gilthead sea bream (Sparus aurata L.) to environmental stress: new insights in fish mitochondrial phenotyping.

  2014cites this paper
• Mitochondrial Biology in Sporadic Inclusion Body Myositis

  2014cites this paper
• Sarcopenie : mécanismes et prévention : rôle de l'exercice et de l'hormone de croissance : implication du stress oxydant et de la glucose-6-phosphate déshydrogénase

  2014cites this paper
• Regulation and quantification of cellular mitochondrial morphology and content.

  2014cites this paper
• Molecular insights into mitochondrial dysfunction in cancer-related muscle wasting.

  2014cites this paper
• Alterations of ultrastructural and fission/fusion markers in hepatocyte mitochondria from mice following calorie restriction with different dietary fats.

  2013cites this paper
• Higher activation of autophagy in skeletal muscle of mice during endurance exercise in the fasted state.

  2013cites this paper
• Protein breakdown in muscle wasting: Role of autophagy-lysosome and ubiquitin-proteasome☆☆☆

  2013cites this paper
• Bladder cancer-induced skeletal muscle wasting: disclosing the role of mitochondria plasticity.

  2013cites this paper
• Ontogeny of muscle bioenergetics in Adelie penguin chicks (Pygoscelis adeliae).

  2013cites this paper
• Mitochondrial Network Genes in the Skeletal Muscle of Amyotrophic Lateral Sclerosis Patients

  2013cites this paper
• Mitochondrial plasticity in pathophysiological conditions

  2013influential citation
• Alterations of Ultrastructural and Fission/Fusion Markers in Hepatocyte Mitochondria From Mice Following Calorie Restriction With Different Dietary Fats

  2013cites this paper
• Skeletal muscle Nur77 expression enhances oxidative metabolism and substrate utilization[S]

  2012cites this paper
• The International Journal of Biochemistry & Cell Biology

  year unknowncites this paper