Inhibitors of poly(adenosine diphosphate-ribose) synthesis: effect on other metabolic processes.

No abstract is available for this paper.

• Publication year

  1984

• Venue

  Science

• Publication date

  1984-02-10

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1126/SCIENCE.6420886PMID 6420886
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• 3-Aminobenzamide, an inhibitor of poly ADP-ribose polymerase, decreases the frequency of alkaline labile lesions and increases growth in human fibroblasts exposed to 3-methyl 4-nitroquinoline 1-oxide.

  1984cited by this paper
• Poly(ADP-ribose) metabolism in ultraviolet irradiated human fibroblasts.

  1983cited by this paper
• Role of DNA breaks and ADP-ribosyl transferase activity in eukaryotic differentiation demonstrated in human lymphocytes

  1982cited by this paper
• DNA strand breaks and ADP-ribosyl transferase activation during cell differentiation

  1982cited by this paper
• Regulation of DNA ligase activity by poly(ADP-ribose)

  1982cited by this paper
• Role of poly(adenosine diphosphate ribose) in deoxyribonucleic acid repair in human fibroblasts.

  1982cited by this paper
• 3 Aminobenzamide, an inhibitor of poly ADP-ribose polymerase, decreases the frequency of alkaline labile lesions and increases growth in human fibroblasts exposed to 3-methyl 4-nitroquinoline 1-oxide

  1982cited by this paper
• Effects of altered [ADP-ribose]n metabolism on expression of fetal functions by adult hepatocytes

  1982cited by this paper
• Poly(ADP-ribosyl)ation of polynucleosomes causes relaxation of chromatin structure.

  1982cited by this paper
• 3-Aminobenzamide synergistically increases sister-chromatid exchanges in cells exposed to methyl methanesulfonate but not to ultraviolet light.

  1982cited by this paper
• Poly(adenosinediphosphoribose) polymerase inhibitors stimulate unscheduled deoxyribonucleic acid synthesis in normal human lymphocytes.

  1982cited by this paper
• ADP-ribosyltransferase activity in cultured hepatocytes. Interactions with DNA repair.

  1982cited by this paper
• Inhibitors of poly-(adenosine diphosphoribose) synthesis slow the resealing rate of x-ray-induced DNA strand breaks.

  1982cited by this paper
• Effect of heat shock on poly(ADP-ribose) synthetase and DNA repair in Drosophila cells.

  1982cited by this paper
• ADP-ribosylation of diadenosine 5',5"-P1,P4-tetraphosphate by poly(ADP-ribose) polymerase in vitro.

  1981cited by this paper
• High incidence of sister chromatid exchanges and chromatid interchanges in the conditions of lowered activity of poly(ADP-ribose)polymerase.

  1981cited by this paper
• Inhibition of (ADP-ribose)n biosynthesis retards DNA repair but does not inhibit DNA repair synthesis.

  1981cited by this paper
• The effect of inhibition of (ADP-ribose)n biosynthesis on DNA repair assayed by the nucleoid technique.

  1981cited by this paper
• Contribution of incorporated 5-bromodeoxyuridine in DNA to the frequencies of sister-chromatid exchanges induced by inhibitors of poly-(ADP-ribose)-polymerase.

  1981cited by this paper
• (ADP-ribose)n participates in DNA excision repair

  1980cited by this paper
• Novel inhibitors of poly(ADP-ribose) synthetase.

  1980cited by this paper
• Nicotinamide stimulates repair of DNA damage in human lymphocytes.

  1980cited by this paper
• The enhancement of cytotoxicity of N-methyl-N-nitrosourea and of gamma-radiation by inhibitors of poly(ADP-ribose) polymerase.

  1980cited by this paper
• Inhibitors of poly(adenosine diphosphate ribose) polymerase induce sister chromatid exchanges.

  1980cited by this paper
• The involvement of poly(ADP-ribose) polymerase in the degradation of NAD caused by gamma-radiation and N-methyl-N-nitrosourea.

  1979cited by this paper
• Poly(ADP-ribose) and ADP-ribosylation of proteins.

  1977cited by this paper
• Poly(ADP-ribose) and ADP-ribosylation of proteins.

  1976cited by this paper
• Evidence for adenosine diphosphate ribosylation of Ca2+, Mg2+-dependent endonuclease.

  1975cited by this paper
• Effects of streptozotocin on glucose metabolism, insulin response, and adiposity in ob/ob mice.

  1975cited by this paper
• Influence of polynucleotides on poly (adenosine diphosphate ribose) synthetase activity of rat liver

  1973cited by this paper
• Depression of DNA polymerase activity in chromatin by incubation with NAD.

  1972cited by this paper
• Lactic Dehydrogenase Activity in Blood.∗

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  2014cites this paper
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  2013cites this paper
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  2013cites this paper
• Therapeutic applications of PARP inhibitors: anticancer therapy and beyond.

  2013cites this paper
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• The potential of the PARP-1 inhibitor, AGO14699, in human cancers defective in homologous recombination DNA repair

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• PARP inhibitors: new partners in the therapy of cancer and inflammatory diseases.

  2009cites this paper
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• A novel poly(ADP-ribose) polymerase inhibitor, ABT-888, radiosensitizes malignant human cell lines under hypoxia.

  2008cites this paper
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  2007cites this paper
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• Modulation of the antiproliferative activity of anticancer drugs in hematopoietic tumor cell lines by the poly(ADP-ribose) polymerase inhibitor 6(5H)-phenanthridinone.

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• The neuroprotective effect of cerebral poly(ADP-ribose)polymerase inhibition in a rat model of global ischemia.

  2000cites this paper
• Involvement of PARP and poly(ADP-ribosyl)ation in the early stages of apoptosis and DNA replication.

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  1999cites this paper
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  1999cites this paper
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  1999cites this paper
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  1999cites this paper
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  1999cites this paper
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  1998cites this paper
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