Biomechanistic insights into the roles of oxidative stress in generating complex neurological disorders

No abstract is available for this paper.

• Publication year

  2017

• Venue

  Biological chemistry

• Publication date

  2017-12-20

• Fields of study

  Medicine, Engineering, Environmental Science

• Identifiers
  DOI 10.1515/hsz-2017-0250PMID 29261511
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• α-Synuclein in Parkinson's disease.

  2012influential reference
• Decreased glutathione accelerates neurological deficit and mitochondrial pathology in familial ALS-linked hSOD1(G93A) mice model.

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• Effect of Polyphenols on Oxidative Stress and Mitochondrial Dysfunction in Neuronal Death and Brain Edema in Cerebral Ischemia

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• Decreased levels of glutathione, the major brain antioxidant, in post-mortem prefrontal cortex from patients with psychiatric disorders.

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• Striatal Dysfunctions Associated with Mitochondrial DNA Damage in Dopaminergic Neurons in a Mouse Model of Parkinson's Disease

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• Lower whole blood glutathione peroxidase (GPX) activity in depression, but not in myalgic encephalomyelitis / chronic fatigue syndrome: another pathway that may be associated with coronary artery disease and neuroprogression in depression.

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• Severe epilepsy as the major symptom of new mutations in the mitochondrial tRNAPhe gene

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• Mitochondrial dysfunction in neurological disorders with epileptic phenotypes

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• Could successful (mitochondrial) networking help prevent Huntington's disease?

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• Genes associated with Parkinson syndrome

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