Mechanism of human somatic reprogramming to iPS cell

No abstract is available for this paper.

• Publication year

  2017

• Venue

  Laboratory Investigation

• Publication date

  2017-05-22

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1038/labinvest.2017.56PMID 28530648
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Metabolome Profiling of Partial and Fully Reprogrammed Induced Pluripotent Stem Cells

  2017cited by this paper
• Identification of the early and late responder genes during the generation of induced pluripotent stem cells from mouse fibroblasts

  2017cited by this paper
• XACT Noncoding RNA Competes with XIST in the Control of X Chromosome Activity during Human Early Development

  2017cited by this paper
• Comprehensive Cell Surface Protein Profiling Identifies Specific Markers of Human Naive and Primed Pluripotent States

  2017cited by this paper
• Pluripotency-associated miR-290/302 family of microRNAs promote the dismantling of naive pluripotency

  2016cited by this paper
• Induced Pluripotent Stem Cells Meet Genome Editing.

  2016cited by this paper
• OCT4 activity during conversion of human intermediately reprogrammed stem cells to iPSCs through mesenchymal-epithelial transition

  2016cited by this paper
• A Broad Overview and Review of CRISPR-Cas Technology and Stem Cells

  2016cited by this paper
• Understanding the molecular mechanisms of reprogramming.

  2016cited by this paper
• Concise Review: Control of Cell Fate Through Cell Cycle and Pluripotency Networks

  2016cited by this paper
• Alternative Routes to Induced Pluripotent Stem Cells Revealed by Reprogramming of the Neural Lineage

  2016cited by this paper
• Generation of pluripotent stem cells without the use of genetic material

  2015cited by this paper
• X chromosome reactivation in reprogramming and in development.

  2015cited by this paper
• Mechanism of Induction: Induced Pluripotent Stem Cells (iPSCs).

  2015cited by this paper
• Phases of reprogramming.

  2014cited by this paper
• Divergent reprogramming routes lead to alternative stem-cell states

  2014cited by this paper
• Manipulation of KLF4 Expression Generates iPSCs Paused at Successive Stages of Reprogramming

  2014cited by this paper
• Generation of pluripotent stem cells via protein transduction.

  2014cited by this paper
• A comparison of non-integrating reprogramming methods

  2014cited by this paper
• Cell Surface Marker Mediated Purification of iPS Cell Intermediates from a Reprogrammable Mouse Model

  2014cited by this paper
• Integration-free Methods for Generating Induced Pluripotent Stem Cells

  2013cited by this paper
• Derivation of novel human ground state naive pluripotent stem cells

  2013cited by this paper
• Critical regulation of miR-200/ZEB2 pathway in Oct4/Sox2-induced mesenchymal-to-epithelial transition and induced pluripotent stem cell generation

  2013cited by this paper
• Regulation of epithelial-mesenchymal and mesenchymal-epithelial transitions by microRNAs.

  2013cited by this paper
• The mesenchymal-to-epithelial transition in somatic cell reprogramming.

  2012cited by this paper
• Human and Mouse Induced Pluripotent Stem Cells Are Differentially Reprogrammed in Response to Kinase Inhibitors

  2012cited by this paper
• Chromatin modifying enzymes as modulators of reprogramming

  2012cited by this paper
• Single-cell expression analyses during cellular reprogramming reveal an early stochastic and a late hierarchic phase.

  2012cited by this paper
• A molecular roadmap of reprogramming somatic cells into iPS cells.

  2012cited by this paper
• Self-Renewal and Pluripotency Acquired through Somatic Reprogramming to Human Cancer Stem Cells

  2012cited by this paper
• The functions of microRNAs in pluripotency and reprogramming

  2012cited by this paper
• Progress made in the reprogramming field: new factors, new strategies and a new outlook.

  2012cited by this paper
• Analysis of endogenous Oct4 activation during induced pluripotent stem cell reprogramming using an inducible Oct4 lineage label.

  2012cited by this paper
• H3K9 methylation is a barrier during somatic cell reprogramming into iPSCs

  2012cited by this paper
• The histone demethylases Jhdm1a/1b enhance somatic cell reprogramming in a vitamin-C-dependent manner.

  2011cited by this paper
• Lonely death dance of human pluripotent stem cells: ROCKing between metastable cell states.

  2011cited by this paper
• Nanog Overcomes Reprogramming Barriers and Induces Pluripotency in Minimal Conditions

  2011cited by this paper
• A genome-wide RNAi screen reveals determinants of human embryonic stem cell identity

  2010cited by this paper
• Induced pluripotency: history, mechanisms, and applications.

  2010cited by this paper
• A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts.

  2010cited by this paper
• Functional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming.

  2010cited by this paper
• When fibroblasts MET iPSCs.

  2010cited by this paper
• Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells

  2010cited by this paper
• Human embryonic stem cells with biological and epigenetic characteristics similar to those of mouse ESCs

  2010cited by this paper
• Elite and stochastic models for induced pluripotent stem cell generation

  2009cited by this paper
• Nanog Is the Gateway to the Pluripotent Ground State

  2009cited by this paper
• Epigenetic reprogramming and induced pluripotency

  2009cited by this paper
• Efficient reprogramming of human and mouse primary extra‐embryonic cells to pluripotent stem cells

  2009cited by this paper
• Klf4 reverts developmentally programmed restriction of ground state pluripotency

  2009cited by this paper
• The ground state of embryonic stem cell self-renewal

  2008cited by this paper
• Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease

  2008cited by this paper
• Sequential expression of pluripotency markers during direct reprogramming of mouse somatic cells.

  2008cited by this paper
• Promotion of Reprogramming to Ground State Pluripotency by Signal Inhibition

  2008cited by this paper
• Dissecting direct reprogramming through integrative genomic analysis

  2008cited by this paper
• Illuminating the black box of reprogramming.

  2008cited by this paper
• Generation of human induced pluripotent stem cells from dermal fibroblasts

  2008cited by this paper
• Defining molecular cornerstones during fibroblast to iPS cell reprogramming in mouse.

  2008cited by this paper
• A ROCK inhibitor permits survival of dissociated human embryonic stem cells

  2007cited by this paper
• Induction of pluripotent stem cells from fibroblast cultures

  2007cited by this paper
• Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors.

  2006cited by this paper
• Core transcriptional regulatory circuitry in human embryonic stem cells.

  2005cited by this paper
• Cell density related gene expression: SV40 large T antigen levels in immortalized astrocyte lines

  2002cited by this paper

• Chemically defined and xeno-free media enables the derivation of human extended pluripotent stem cell lines from discarded blastocysts with a high efficiency

  2025cites this paper
• Breaking Barriers in Huntington’s Disease Therapy: Focused Ultrasound for Targeted Drug Delivery

  2025cites this paper
• Nitric oxide and peroxynitrite as new biomarkers for early diagnosis of autism.

  2025cites this paper
• Conserved Biological Processes in Partial Cellular Reprogramming: Relevance to Aging and Rejuvenation.

  2025cites this paper
• A Dual Role of HGF-ERK Signaling in IL6/HGF-induced Hepatocyte Proliferation

  2025cites this paper
• Melatonin Augments the Expression of Core Transcription Factors in Aged and Alzheimer’s Patient Skin Fibroblasts

  2024cites this paper
• The hope, hype and obstacles surrounding cell therapy

  2024cites this paper
• Profiling the role of m6A effectors in the regulation of pluripotent reprogramming

  2024cites this paper
• The long and winding road of reprogramming-induced rejuvenation

  2024cites this paper
• Epigenetic Reprogramming as a Key to Reverse Ageing and Increase Longevity.

  2024cites this paper
• Mesenchymal stem cell transplantation plays a role in relieving cancer pain

  2024cites this paper
• Lactate-mediated lactylation in human health and diseases: Progress and remaining challenges

  2024cites this paper
• Loss of ADAM29 does not affect viability and fertility in mice but improves wound healing

  2024cites this paper
• Profiling A-to-I RNA editing during mouse somatic reprogramming at the single-cell level

  2023cites this paper
• Exploring the promising potential of induced pluripotent stem cells in cancer research and therapy

  2023cites this paper
• Unlocking cellular plasticity: Enhancing human iPSC reprogramming through bromodomain inhibition and extracellular matrix gene expression regulation

  2023cites this paper
• Research Progress of Cardiac Reprogramming in the Repair of Myocardial Infarction

  2023cites this paper
• The E1a Adenoviral Gene Upregulates the Yamanaka Factors to Induce Partial Cellular Reprogramming

  2023cites this paper
• Predicting reprogramming-related gene expression from cell morphology in human induced pluripotent stem cells

  2023cites this paper
• Human induced pluripotent stem cell formation and morphology prediction during reprogramming with time-lapse bright-field microscopy images using deep learning methods

  2022cites this paper
• Non-human primate pluripotent stem cells for the preclinical testing of regenerative therapies

  2022cites this paper
• Die Rolle von Stammzellen beim biologischen Altern

  2022cites this paper
• An allied reprogramming, selection, expansion and differentiation platform for creating hiPSC on microcarriers

  2022cites this paper
• Predicting gene expression from cell morphology in human induced pluripotent stem cells

  2022cites this paper
• High and low permeability of human pluripotent stem cell-derived Blood Brain barrier models depend on epithelial or endothelial features

  2022cites this paper
• Challenges with Cell-based Therapies for Type 1 Diabetes Mellitus

  2022cites this paper
• Advances in Cellular Reprogramming-Based Approaches for Heart Regenerative Repair

  2022cites this paper
• Novel in vitro Experimental Approaches to Study Myelination and Remyelination in the Central Nervous System

  2021cites this paper
• Multi-omic rejuvenation of human cells by maturation phase transient reprogramming

  2021cites this paper
• Transient reprogramming of postnatal cardiomyocytes to a dedifferentiated state

  2021cites this paper
• Context-aware synthetic biology by controller design: Engineering the mammalian cell.

  2021cites this paper
• Molecular signature and colony morphology affect in vitro pluripotency of porcine induced pluripotent stem cells.

  2021cites this paper
• Bioengineering Technologies for Cardiac Regenerative Medicine

  2021cites this paper
• N-Cadherin Nanoantagonist Driven Mesenchymal-to-Epithelial Transition in Fibroblasts for Improving Reprogramming Efficiency.

  2021cites this paper
• Blood–Brain Barrier and Neurodegenerative Diseases—Modeling with iPSC-Derived Brain Cells

  2021cites this paper
• Pluripotent stem-cell-derived oligodendrocyte progenitors to model demyelination caused by Theiler’s murine encephalomyelitis virus and other viruses

  2021cites this paper
• Ribosome-Induced Cellular Multipotency, an Emerging Avenue in Cell Fate Reversal

  2021cites this paper
• Revealing cell fate decisions during reprogramming by scRNA-seq

  2020cites this paper
• Reprogramming of chimpanzee fibroblasts into a multipotent cancerous but not fully pluripotent state by transducing iPSC factors in 2i/LIF culture.

  2020cites this paper
• Stem cell technologies in the comprehensive treatment of autism spectrum disorders

  2020cites this paper
• Induced Pluripotency: A Powerful Tool for In Vitro Modeling

  2020cites this paper
• Development of a High-Efficacy Reprogramming Method for Generating Human Induced Pluripotent Stem (iPS) Cells from Pathologic and Senescent Somatic Cells

  2020cites this paper
• Microengineered systems with iPSC-derived cardiac and hepatic cells to evaluate drug adverse effects

  2020cites this paper
• iPSC-Derived Liver Organoids: A Journey from Drug Screening, to Disease Modeling, Arriving to Regenerative Medicine

  2020cites this paper
• Invited contribution to the volume: "Stem cells & cancer stem cells, regenerative medicine & cancer" (VSI stem cells) reprogramming and transdifferentiation - two key processes for regenerative medicine.

  2020cites this paper
• Modeling Psychiatric Disorder Biology with Stem Cells

  2020cites this paper
• Frequent retrotransposition of endogenous genes in ERCC2-deficient cells derived from a patient with xeroderma pigmentosum

  2019cites this paper
• Visualization of sequential conversion of human intermediately reprogrammed stem cells into iPS cells

  2019cites this paper
• Amnion-derived cells as a reliable resource for next-generation regenerative medicine.

  2019cites this paper
• Autonomous trisomic rescue of Down syndrome cells

  2019cites this paper
• Transient Reprogramming of Neonatal Cardiomyocytes to a Proliferative Dedifferentiated State

  2019cites this paper
• Establishment of a Gorlin syndrome model from induced neural progenitor cells exhibiting constitutive GLI1 expression and high sensitivity to inhibition by smoothened (SMO)

  2019cites this paper
• Media switching at different time periods affects the reprogramming efficiency of buffalo fetal fibroblasts

  2019cites this paper
• Immortalization of human hepatocytes from biliary atresia with CDK4R24C, cyclin D1, and TERT for cytochrome P450 induction testing

  2019cites this paper
• Time-course transcriptome analysis of human cellular reprogramming from multiple cell types reveals the drastic change occurs between the mid phase and the late phase

  2018cites this paper
• Epigenetic-scale comparison of human iPSCs generated by retrovirus, Sendai virus or episomal vectors

  2018cites this paper
• Enhanced human somatic cell reprogramming efficiency by fusion of the MYC transactivation domain and OCT4.

  2017cites this paper