A Large Fraction of Extragenic RNA Pol II Transcription Sites Overlap Enhancers

Francesca De Santa,I. Barozzi,F. Mietton,S. Ghisletti,S. Polletti,B. Tusi,H. Muller,J. Ragoussis,Chia-Lin Wei,G. Natoli

Published 2010 in PLoS Biology

ABSTRACT

A substantial fraction of extragenic Pol II transcription sites coincides with transcriptional enhancers, which may be relevant for functional annotation of mammalian genomes.

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