Neural regeneration in Caenorhabditis elegans.

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Annual Review of Genetics

• Publication date

  2012-11-12

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1146/annurev-genet-110711-155550PMID 22974301PMCID PMC3700416
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Sensory axon regeneration: rebuilding functional connections in the spinal cord.

  2012cited by this paper
• Notch signaling inhibits axon regeneration.

  2012cited by this paper
• Identity by descent between distant relatives: detection and applications.

  2012cited by this paper
• Dicer-microRNA pathway is critical for peripheral nerve regeneration and functional recovery in vivo and regenerative axonogenesis in vitro.

  2012cited by this paper
• The growth factor SVH-1 regulates axon regeneration in C. elegans via the JNK MAPK cascade

  2012cited by this paper
• Rules of engagement: molecular insights from host-virus arms races.

  2012cited by this paper
• Fusion and fission: interlinked processes critical for mitochondrial health.

  2012cited by this paper
• Transposable elements: an abundant and natural source of regulatory sequences for host genes.

  2012cited by this paper
• Understanding the relationship between brain gene expression and social behavior: lessons from the honey bee.

  2012cited by this paper
• The CRISPRs, they are a-changin': how prokaryotes generate adaptive immunity.

  2012cited by this paper
• Uncovering the molecular and cellular mechanisms of heart development using the zebrafish.

  2012cited by this paper
• The biosynthetic capacities of the plastids and integration between cytoplasmic and chloroplast processes.

  2012cited by this paper
• Myelin associated inhibitors: a link between injury-induced and experience-dependent plasticity.

  2012cited by this paper
• Microtubule Stabilization Reduces Scarring and Causes Axon Regeneration After Spinal Cord Injury

  2011cited by this paper
• Microtubule depolymerization in Caenorhabditis elegans touch receptor neurons reduces gene expression through a p38 MAPK pathway

  2011cited by this paper
• MicroRNA dysregulation following spinal cord contusion: implications for neural plasticity and repair.

  2011cited by this paper
• The development and application of optogenetics.

  2011cited by this paper
• Axon regeneration mechanisms: insights from C. elegans.

  2011cited by this paper
• Interaction Between Notch and Hif-α in Development and Survival of Drosophila Blood Cells

  2011cited by this paper
• Spontaneous Age-Related Neurite Branching in Caenorhabditis elegans

  2011cited by this paper
• Synergy between the ESCRT-III complex and Deltex defines a ligand-independent Notch signal

  2011cited by this paper
• Axonal regeneration proceeds through specific axonal fusion in transected C. elegans neurons

  2011cited by this paper
• Roles of Drosophila Deltex in Notch receptor endocytic trafficking and activation

  2011cited by this paper
• Sustained axon regeneration induced by co-deletion of PTEN and SOCS3

  2011cited by this paper
• Constructing a Low-budget Laser Axotomy System to Study Axon Regeneration in C. elegans

  2011cited by this paper
• MicroRNA miR‐133b is essential for functional recovery after spinal cord injury in adult zebrafish

  2011cited by this paper
• Axon regeneration requires coordinate activation of p38 and JNK MAPK pathways

  2011cited by this paper
• Taxol Facilitates Axon Regeneration in the Mature CNS

  2011cited by this paper
• Axon regeneration pathways identified by systematic genetic screening in C. elegans.

  2011cited by this paper
• Large-scale in vivo femtosecond laser neurosurgery screen reveals small-molecule enhancer of regeneration

  2010cited by this paper
• Caenorhabditis elegans EFA-6 limits microtubule growth at the cell cortex

  2010cited by this paper
• Global Up-Regulation of Microtubule Dynamics and Polarity Reversal during Regeneration of an Axon from a Dendrite

  2010cited by this paper
• The Fusogen EFF-1 Controls Sculpting of Mechanosensory Dendrites

  2010cited by this paper
• PTEN Inhibition to Facilitate Intrinsic Regenerative Outgrowth of Adult Peripheral Axons

  2010cited by this paper
• The C. elegans peroxidasin PXN-2 is essential for embryonic morphogenesis and inhibits adult axon regeneration

  2010cited by this paper
• Calcium and Cyclic AMP Promote Axonal Regeneration in Caenorhabditis elegans and Require DLK-1 Kinase

  2010cited by this paper
• Notch signaling: the core pathway and its posttranslational regulation.

  2009cited by this paper
• The DLK-1 kinase promotes mRNA stability and local translation in C. elegans synapses and axon regeneration.

  2009cited by this paper
• Axon Regeneration Requires a Conserved MAP Kinase Pathway

  2009cited by this paper
• SOCS3 deletion promotes optic nerve regeneration in vivo.

  2009cited by this paper
• Impaired regenerative response of primary sensory neurons in ZPK/DLK gene-trap mice.

  2009cited by this paper
• Optical interrogation of neural circuits in Caenorhabditis elegans

  2009cited by this paper
• Axonal growth therapeutics: regeneration or sprouting or plasticity?

  2008cited by this paper
• Calcium-assisted glass-to-glass bonding for fabrication of glass microfluidic devices.

  2008cited by this paper
• In vivo nanosecond laser axotomy: cavitation dynamics and vesicle transport.

  2008cited by this paper
• Drosophila HOPS and AP-3 complex genes are required for a Deltex-regulated activation of notch in the endosomal trafficking pathway.

  2008cited by this paper
• OSM-11 Facilitates LIN-12 Notch Signaling during Caenorhabditis elegans Vulval Development

  2008cited by this paper
• Promoting Axon Regeneration in the Adult CNS by Modulation of the PTEN/mTOR Pathway

  2008cited by this paper
• Distinct cellular and molecular mechanisms mediate initial axon development and adult-stage axon regeneration in C. elegans

  2008cited by this paper
• Oxidative damage to extracellular matrix and its role in human pathologies.

  2008cited by this paper
• The C. elegans F-spondin family protein SPON-1 maintains cell adhesion in neural and non-neural tissues

  2008cited by this paper
• RPM-1, a Caenorhabditis elegans Protein That Functions in Presynaptic Differentiation, Negatively Regulates Axon Outgrowth by Controlling SAX-3/robo and UNC-5/UNC5 Activity

  2008cited by this paper
• Femtosecond laser nanoaxotomy lab-on-a-chip for in vivo nerve regeneration studies

  2008cited by this paper
• Disorganized Microtubules Underlie the Formation of Retraction Bulbs and the Failure of Axonal Regeneration

  2007cited by this paper
• Caenorhabditis elegans neuronal regeneration is influenced by life stage, ephrin signaling, and synaptic branching

  2007cited by this paper
• Axons break in animals lacking β-spectrin

  2007cited by this paper
• Femtosecond laser nanoaxotomy properties and their effect on axonal recovery in C. elegans.

  2007cited by this paper
• The making of successful axonal regeneration: genes, molecules and signal transduction pathways.

  2007cited by this paper
• Functional Axonal Regeneration through Astrocytic Scar Genetically Modified to Digest Chondroitin Sulfate Proteoglycans

  2007cited by this paper
• Microfluidic system for on-chip high-throughput whole-animal sorting and screening at subcellular resolution

  2007cited by this paper
• C. elegans RPM-1 regulates axon termination and synaptogenesis through the Rab GEF GLO-4 and the Rab GTPase GLO-1.

  2007cited by this paper
• Myeloperoxidase Inactivates TIMP-1 by Oxidizing Its N-terminal Cysteine Residue

  2007cited by this paper
• Regulation of intrinsic neuronal properties for axon growth and regeneration.

  2007cited by this paper
• Glial inhibition of CNS axon regeneration

  2006cited by this paper
• Characterization of loss-of-function and gain-of-function Eph receptor tyrosine kinase signaling in C. elegans axon targeting and cell migration.

  2006cited by this paper
• Can regenerating axons recapitulate developmental guidance during recovery from spinal cord injury?

  2006cited by this paper
• Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 Regulates Tumor Necrosis Factor mRNA Stability and Translation Mainly by Altering Tristetraprolin Expression, Stability, and Binding to Adenine/Uridine-Rich Element

  2006cited by this paper
• The neuronal microRNA system

  2006cited by this paper
• The role of the AFD neuron in C. elegans thermotaxis analyzed using femtosecond laser ablation

  2006cited by this paper
• Practice makes perfect: the neural substrates of tactile discrimination by Mah-Jong experts include the primary visual cortex

  2006cited by this paper
• Chondroitinase ABC Promotes Sprouting of Intact and Injured Spinal Systems after Spinal Cord Injury

  2006cited by this paper
• Degradation of Chondroitin Sulfate Proteoglycans Induces Sprouting of Intact Purkinje Axons in the Cerebellum of the Adult Rat

  2005cited by this paper
• Regulation of a DLK-1 and p38 MAP kinase pathway by the ubiquitin ligase RPM-1 is required for presynaptic development.

  2005cited by this paper
• Cyclic AMP-Induced Repair of Zebrafish Spinal Circuits

  2004cited by this paper
• The Caenorhabditis elegans MAPK phosphatase VHP‐1 mediates a novel JNK‐like signaling pathway in stress response

  2004cited by this paper
• Regeneration beyond the glial scar

  2004cited by this paper
• Calcium Entry through L-Type Calcium Channels Is Essential for Neurite Regeneration in Cultured Sympathetic Neurons

  2004cited by this paper
• Notch activity acts as a sensor for extracellular calcium during vertebrate left–right determination

  2004cited by this paper
• The lateral signal for LIN-12/Notch in C. elegans vulval development comprises redundant secreted and transmembrane DSL proteins.

  2004cited by this paper
• Neurosurgery: Functional regeneration after laser axotomy

  2004cited by this paper
• Drosophila Deltex mediates Suppressor of Hairless-independent and late-endosomal activation of Notch signaling

  2004cited by this paper
• Myelin-associated inhibitors of axonal regeneration in the adult mammalian CNS

  2003cited by this paper
• The Nogo-66 receptor: focusing myelin inhibition of axon regeneration.

  2003cited by this paper
• Myelin-associated inhibitors of axonal regeneration in the adult mammalian CNS

  2003cited by this paper
• A Novel Ankyrin Repeat-containing Gene (Kank) Located at 9p24 Is a Growth Suppressor of Renal Cell Carcinoma*

  2002cited by this paper
• The type I membrane protein EFF-1 is essential for developmental cell fusion.

  2002cited by this paper
• Spinal axon regeneration induced by elevation of cyclic AMP.

  2002cited by this paper
• Inhibitors of regeneration in myelin along with proteoglycans of the immature scar then prevent growth immediately after injury

  2002cited by this paper
• A role for cAMP in regeneration during development and after injury.

  2002cited by this paper
• Regeneration of sensory axons within the injured spinal cord induced by intraganglionic cAMP elevation.

  2002cited by this paper
• Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing.

  2001cited by this paper
• Regulation of presynaptic terminal organization by C. elegans RPM-1, a putative guanine nucleotide exchanger with a RING-H2 finger domain.

  2000cited by this paper
• rpm-1, a conserved neuronal gene that regulates targeting and synaptogenesis in C. elegans.

  2000cited by this paper
• Mutations in β-Spectrin Disrupt Axon Outgrowth and Sarcomere Structure

  2000cited by this paper
• Calcium Depletion Dissociates and Activates Heterodimeric Notch Receptors

  2000cited by this paper
• One GABA and two acetylcholine receptors function at the C. elegans neuromuscular junction

  1999cited by this paper
• Regeneration of dorsal column fibers into and beyond the lesion site following adult spinal cord injury.

  1999cited by this paper
• EFA6, a sec7 domain‐containing exchange factor for ARF6, coordinates membrane recycling and actin cytoskeleton organization

  1999cited by this paper
• Axotomy induces a transient and localized elevation of the free intracellular calcium concentration to the millimolar range.

  1995cited by this paper
• Adenylyl cyclases and the interaction between calcium and cAMP signalling

  1995cited by this paper

• C. elegans Spastin/spas-1 Is Required for Axon Regeneration and Maintenance

  2026cites this paper
• Elevated mitochondrial superoxide promotes longevity through a mitochondria-to-nucleus kinase signaling pathway

  2025cites this paper
• Evolution and Function of the Notch Signaling Pathway: An Invertebrate Perspective

  2024cites this paper
• Repurposing the Killing Machine: Non-canonical Roles of the Cell Death Apparatus in Caenorhabditis elegans Neurons

  2022cites this paper
• Gradual specialization of phagocytic ameboid cells may have impaired regenerative capacities in metazoan lineages

  2022cites this paper
• The utilization of small non‐mammals in traumatic brain injury research: A systematic review

  2021cites this paper
• Multiple neuronal networks coordinate Hydra mechanosensory behavior

  2021cites this paper
• UNC-16 alters DLK-1 localization and negatively regulates actin and microtubule dynamics in Caenorhabditis elegans regenerating neurons.

  2021cites this paper
• The peroxisomal fatty acid transporter ABCD1/PMP-4 is required in the C. elegans hypodermis for axonal maintenance: A worm model for adrenoleukodystrophy.

  2020cites this paper
• Multiple nerve rings coordinate Hydra mechanosensory behavior

  2020cites this paper
• Designing neuroreparative strategies using aged regenerating animal models.

  2020cites this paper
• Disruption of RAB-5 Increases EFF-1 Fusogen Availability at the Cell Surface and Promotes the Regenerative Axonal Fusion Capacity of the Neuron

  2019cites this paper
• Progress in Neurobiology

  2019cites this paper
• Axonal fusion: An alternative and efficient mechanism of nerve repair

  2019cites this paper
• Neurological Disorder Brain Model: A Lesson from Marine Worms (Annelida: Polychaeta)

  2019cites this paper
• Mechanisms that regulate morphogenesis of a highly branched neuron in C. elegans.

  2019cites this paper
• Impact of ionising radiation on adult neurogenesis: physiological and cellular effects of low and moderate doses of ionising radiation in neural differentiation distinguished by differentiation phase

  2018cites this paper
• Functional Genome-wide Screen Identifies Pathways Restricting Central Nervous System Axonal Regeneration.

  2018cites this paper
• Nerve regeneration in the cephalopod mollusc Octopus vulgaris: label-free multiphoton microscopy as a tool for investigation

  2018cites this paper
• RAB-5 regulates regenerative axonal fusion by controlling EFF-1 endocytosis

  2018cites this paper
• Nervous System Ageing

  2017cites this paper
• Signal transduction cascades in axon regeneration: insights from C. elegans.

  2017cites this paper
• Lentivirus Mediating FGF13 Enhances Axon Regeneration after Spinal Cord Injury by Stabilizing Microtubule and Improving Mitochondrial Function

  2017cites this paper
• The Genetics of Axon Guidance and Axon Regeneration in Caenorhabditis elegans

  2016cites this paper
• Chapter 5 Nervous System Ageing

  2016cites this paper
• Mitochondria Localize to Injured Axons to Support Regeneration.

  2016cites this paper
• Chemical biology studies of neuroregenerative small molecules using Caenorhabditis elegans

  2015cites this paper
• Hope on the (fruit) fly: the Drosophila wing paradigm of axon injury

  2015cites this paper
• Expedited access to vinaxanthone and chemically edited derivatives possessing neuronal regenerative effects through ynone coupling reactions.

  2015cites this paper
• Advances and Challenges for Neural Regeneration Research

  2015cites this paper
• An assay to image neuronal microtubule dynamics in mice

  2014cites this paper
• Imaging microtubule dynamics in the healthy and diseased nervous system

  2014cites this paper
• Studying axonal degeneration and regeneration using in vitro and in vivo models: the translational potential

  2014cites this paper
• Axon regeneration in C. elegans.

  2014cites this paper
• Ion Channels in Regulation of Neuronal Regenerative Activities

  2014cites this paper
• Exposure to Mitochondrial Genotoxins and Dopaminergic Neurodegeneration in Caenorhabditis elegans

  2014cites this paper
• Insulin/IGF1 signaling inhibits age-dependent axon regeneration.

  2014cites this paper
• Axon Injury and Regeneration in the Adult Drosophila

  2014cites this paper
• A Fully Automated Microfluidic Femtosecond Laser Axotomy Platform for Nerve Regeneration Studies in C. elegans

  2014cites this paper
• Cell death proteins: An evolutionary role in cellular adaptation before the advent of apoptosis

  2013cites this paper
• Spinal cord regeneration: where fish, frogs and salamanders lead the way, can we follow?

  2013cites this paper
• Signaling pathways that regulate axon regeneration

  2013cites this paper
• Cytoskeletal dynamics in Caenorhabditis elegans axon regeneration.

  2013cites this paper
• Design and implementation of in vivo imaging of neural injury responses in the adult Drosophila wing

  2013cites this paper