T cell receptor beta gene sequences in the circular DNA of thymocyte nuclei: direct evidence for intramolecular DNA deletion in V-D-J joining.

No abstract is available for this paper.

• Publication year

  1987

• Venue

  Cell

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 3502705
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Reciprocal recombination products of VK-JK joining reactions in human lymphoid cell lines

  1987cited by this paper
• Structure, function, and serology of the T-cell antigen receptor complex.

  1987cited by this paper
• The molecular genetics of the T-cell antigen receptor and T-cell antigen recognition.

  1986cited by this paper
• Non-germ-line elements (NGE) are present in the T cell receptor beta-chain genes isolated from the mutant mouse, motheaten (me/me).

  1986cited by this paper
• Endonucleolytic activity that cleaves immunoglobulin recombination sequences.

  1986cited by this paper
• Direct evidence for chromosomal inversion during T-cell receptor β-gene rearrangements

  1986cited by this paper
• Two types of immunoglobulin-negative Abelson murine leukemia virus-transformed cells: implications for B-lymphocyte differentiation.

  1986cited by this paper
• Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC19 vectors.

  1985cited by this paper
• Rearrangement and transcription of the β-chain genes of the T-cell antigen receptor in different types of murine lymphocytes

  1985cited by this paper
• The murine T-cell receptor uses a limited repertoire of expressed Vβ gene segments

  1985cited by this paper
• Critical test of a sister chromatid exchange model for the immunoglobulin heavy-chain class switch

  1985cited by this paper
• Transposon-like sequences in extrachromosomal circular DNA from mouse thymocytes.

  1985cited by this paper
• DNA elements are asymmetrically joined during the site-specific recombination of kappa immunoglobulin genes.

  1985cited by this paper
• Characterization of immunoglobulin enhancer deletions in murine plasmacytomas.

  1985cited by this paper
• Mouse T cell antigen receptor: structure and organization of constant and joining gene segments encoding the beta polypeptide.

  1984cited by this paper
• Genomic organization and sequence of T-cell receptor β-chain constant- and joining-region genes

  1984cited by this paper
• Somatic recombination in a murine T-cell receptor gene

  1984cited by this paper
• The structure, rearrangement and expression of Dβ gene segments of the murine T-cell antigen receptor

  1984cited by this paper
• Localization of a T-cell receptor diversity-region element

  1984cited by this paper
• Site-specific recombination between immunoglobulin D and JH segments that were introduced into the genome of a murine pre-B cell line.

  1984cited by this paper
• Translocation of the myc cellular oncogene to the immunoglobulin heavy chain locus in murine plasmacytomas is an imprecise reciprocal exchange.

  1984cited by this paper
• Intervening sequences in chloroplast genomes.

  1984cited by this paper
• Sequence repetition and genomic distribution of small polydisperse circular DNA purified from HeLa cells.

  1984cited by this paper
• Joining of V kappa to J kappa gene segments in a retroviral vector introduced into lymphoid cells.

  1984cited by this paper
• Ordered rearrangement of immunoglobulin heavy chain variable region segments.

  1984cited by this paper
• Purification of small polydisperse circular DNA of eukaryotic cells by use of ATP-dependent deoxyribonuclease.

  1983cited by this paper
• A novel type of aberrant recombination in immunoglobulin genes and its implications for V–J joining mechanism

  1983cited by this paper
• DNA between variable and joining gene segments of immunoglobulin kappa light chain is frequently retained in cells that rearrange the kappa locus.

  1982cited by this paper
• Small circular DNA complexes in eucaryotic cells.

  1982cited by this paper
• Continuing kappa-gene rearrangement in a cell line transformed by Abelson murine leukemia virus.

  1982cited by this paper
• Joining of immunoglobulin heavy chain gene segments: implications from a chromosome with evidence of three D-JH fusions.

  1982cited by this paper
• Determination of nucleotide sequences in DNA

  1981cited by this paper
• Identification and nucleotide sequence of a diversity DNA segment (D) of immunoglobulin heavy-chain genes

  1981cited by this paper
• Rearrangements of Immunoglobulin Genes during Differentiation and Evolution

  1981cited by this paper
• An immunoglobulin heavy chain variable region gene is generated from three segments of DNA: VH, D and JH.

  1980cited by this paper
• Immunoglobulin V/J recombination is accompanied by deletion of joining site and variable region segments.

  1980cited by this paper
• Two types of somatic recombination are necessary for the generation of complete immunoglobulin heavy-chain genes

  1980cited by this paper
• A rearranged DNA sequence possibly related to the translocation of immunoglobulin gene segments.

  1980cited by this paper
• Deletions are associated with somatic rearrangement of immunoglobulin heavy chain genes.

  1980cited by this paper
• Sequences of five potential recombination sites encoded close to an immunoglobulin kappa constant region gene.

  1979cited by this paper
• In vitro packaging of lambda and cosmid DNA.

  1979cited by this paper
• Sequences at the somatic recombination sites of immunoglobulin light-chain genes

  1979cited by this paper
• A new method for sequencing DNA.

  1977cited by this paper
• Small circular DNA in Drosophila melanogaster.

  1976cited by this paper
• Somatic generation of antibody diversity.

  1976cited by this paper
• Stimulation by Cyclic Adenosine Monophosphate of Plasmid Deoxyribonucleic Acid Replication and Catabolite Repression of the Plasmid Deoxyribonucleic Acid-Protein Relaxation Complex

  1973cited by this paper
• Small polydisperse circular DNA of HeLa cells.

  1972cited by this paper

• The newfound relationship between extrachromosomal DNAs and excised signal circles.

  2026cites this paper
• Landscape of extrachromosomal DNA characteristics in high-grade serous ovarian cancer via long-read sequencing.

  2025cites this paper
• The nexus of dynamic T cell states and immune checkpoint blockade therapy in the periphery and tumor microenvironment

  2023cites this paper
• Parallel sequencing of extrachromosomal circular DNAs and transcriptomes in single cancer cells

  2023cites this paper
• Immunogenetic Aspect of B-Cell Antigen Receptor Diversity Generation

  2020cites this paper
• Characteristics of TCR Repertoire Associated With Successful Immune Checkpoint Therapy Responses

  2020cites this paper
• Newborn Screening for Severe Combined Immunodeficiency-A History of the TREC Assay

  2017cites this paper
• Resource System-wide Analysis of t he T Cell Response Graphical Abstract Highlights

  2016cites this paper
• System-wide Analysis of the T Cell Response.

  2016cites this paper
• Violation of the 12/23 rule of genomic V(D)J recombination is common in lymphocytes

  2015cites this paper
• The Mechanism of V(D)J Recombination

  2015cites this paper
• Rearrangement of Variable Region T Cell Receptor y Genes in Acute Lymphoblastic Leukemia Vy Gene Usage Differs in Mature and Immature T Cells

  2013cites this paper
• Immunity and tolerance to the tumor-associated antigen MUC1

  2009cites this paper
• Dinamica virale e risposta immune HIV-1-specifica in neonati sottoposti a terapia antiretrovirale ed immunoricostituzione in bambini infettati da HIV-1 con differente risposta virologica alla terapia

  2008cites this paper
• Recovering probabilities for nucleotide trimming processes for T cell receptor TRA and TRG V-J junctions analyzed with IMGT tools

  2008cites this paper
• Interleukin-7 and hematopoietic stem cell transplantation: beyond the thymus

  2007cites this paper
• Gene discovery at the human T-cell receptor α/δ locus

  2007cites this paper
• Formation of non-random extrachromosomal elements during development, differentiation and oncogenesis.

  2007cites this paper
• Gene discovery at the human T-cell receptor alpha/delta locus.

  2007cites this paper
• Somatic DNA recombination in the brain.

  2006cites this paper
• Peptides as Targets of T Cell-Mediated Immune Responses

  2006cites this paper
• Lymphocyte homeostasis and the antitumor immune response

  2005cites this paper
• Recent thymic emigrants and subsets of naive and memory T cells in the circulation of patients with head and neck cancer.

  2005cites this paper
• The positional effect of Eβ on Vβ genes of TCRβ chain in the ordered rearrangement and allelic exclusion

  2005cites this paper
• Mechanism and control of V(D)J recombination versus class switch recombination: similarities and differences.

  2005cites this paper
• The positional effect of Ebeta on Vbeta genes of TCRbeta chain in the ordered rearrangement and allelic exclusion.

  2005cites this paper
• CHAPTER 5 – The Mechanism of V(D)J Recombination

  2004cites this paper
• Somatic DNA recombination yielding circular DNA and deletion of a genomic region in embryonic brain.

  2004cites this paper
• Immunology of HIV — filling in the details

  2004cites this paper
• One neuron-one receptor rule in the mouse olfactory system.

  2004cites this paper
• T‐Cell Receptor Excisional Circles, Telomere Length, Proliferation and Apoptosis in Peripheral Blood Mononuclear Cells of Human Immunodeficiency Virus‐Infected Individuals after 18 Months of Treatment Induced Viral Suppression

  2003cites this paper
• Our "Shagreen leather" is our problem. And we have to solve it. 3. A missing link

  2003cites this paper
• Extrathymic Development of Vcd 4-positive T Cells

  2003cites this paper
• Quantification of newly developed T cells in mice by real-time quantitative PCR of T-cell receptor rearrangement excision circles.

  2002cites this paper
• V(D)J recombination: RAG proteins, repair factors, and regulation.

  2002cites this paper
• Sélection centrale, survie et sélection périphérique des lymphocytes T ab CD8+

  2002cites this paper
• Production of New T Cells by Thymus in Children: Effect of HIV Infection and Antiretroviral Therapy

  2002cites this paper
• Synthesis of the T cell receptor chains

  2001cites this paper
• T cell receptor excision circle (TREC) content following maximum HIV suppression is equivalent in HIV-infected and HIV-uninfected individuals

  2001cites this paper
• Efficient generation of human T cells from a tissue-engineered thymic organoid

  2000cites this paper
• Extrachromosomal DNA in eukaryotic cells

  2000cites this paper
• Effect of recent thymic emigrants on progression of HIV-1 disease.

  2000cites this paper
• Direct Evidence for Thymic Function in Adult Humans

  1999cites this paper
• Regulated Formation of Extrachromosomal Circular DNA Molecules during Development in Xenopus laevis

  1999cites this paper
• Measuring Recent Thymic Emigrants in Blood of Normal and HIV-1–Infected Individuals before and after Effective Therapy

  1999cites this paper
• The Biological Function Paradigm Applied to the Immunological Self-Non-Self Discrimination: Critique of Tauber's Phenomenological Analysis

  1999cites this paper
• T cell receptor gene deletion circles identify recent thymic emigrants in the peripheral T cell pool.

  1999cites this paper
• Thymic function can be accurately monitored by the level of recent T cell emigrants in the circulation.

  1998cites this paper
• Variable gene segment-specific N-insertions at the signal joint of T-cell receptor Vβ-Dβ recombinations

  1998cites this paper
• Variable gene segment-specific N-insertions at the signal joint of T-cell receptor Vbeta-Dbeta recombinations.

  1998cites this paper
• Immunology: The thymus in the age of retirement

  1998cites this paper
• Intestinal intraepithelial lymphocytes include precursors committed to the T cell receptor αβ lineage

  1998cites this paper
• Intestinal intraepithelial lymphocytes include precursors committed to the T cell receptor alpha beta lineage.

  1998cites this paper
• Small polydispersed circular DNA (spcDNA) in human cells: association with genomic instability

  1997cites this paper
• Ig Sgamma3 DNA-specifc double strand breaks are induced in mitogen-activated B cells and are implicated in switch recombination.

  1997cites this paper
• Molecular characterization of extrachromosomal circular DNAs from differentiating embryonic stem cells.

  1996cites this paper
• Junctional diversity in signal joints from T cell receptor beta and delta loci via terminal deoxynucleotidyl transferase and exonucleolytic activity

  1996cites this paper
• T-cell receptor alpha locus V(D)J recombination by-products are abundant in thymocytes and mature T cells

  1996cites this paper
• T cell receptors and T cell development.

  1996cites this paper
• Identification of a member of the TIS11 early response gene family at the insertion point of a DNA fragment containing a gene for the T-cell receptor beta chain in an acute T-cell leukemia.

  1995cites this paper
• The variable region gene assembly mechanism

  1995cites this paper
• Analysis of recombination junctions in extrachromosomal circular DNA obtained by in‐gel competitive reassociation

  1995cites this paper
• V(D)J recombination of immunoglobulin genes.

  1995cites this paper
• Extrathymic differentiation of a T cell bearing invariant V alpha 14J alpha 281 TCR.

  1994cites this paper
• Extrathymic Differentiation of a T Cell Bearing Invariant Vα14Jα281 TCR

  1994cites this paper
• Somatic hypermutation and germline evolution of immunoglobulin variable genes

  1994cites this paper
• Abnormal deletions in the T-cell receptor delta locus of mouse thymocytes

  1994cites this paper
• The mechanism of V(D)J joining: lessons from molecular, immunological, and comparative analyses.

  1994cites this paper
• V(D)J recombination generates a high frequency of nonstandard TCR D delta-associated rearrangements in thymocytes.

  1993cites this paper
• Increased amount and contour length distribution of small polydisperse circular DNA (spcDNA) in Fanconi anemia.

  1993cites this paper
• Unequal signal and coding joint formation in human V(D)J recombination

  1993cites this paper
• Elimination of Tec elements involves a novel excision process.

  1993cites this paper
• Molecular characterization of extrachromosomal circular DNAs from an embryonal carcinoma cell line induced to differentiate into neuron-like cells in vitro.

  1993cites this paper
• IL-4 induction of IgE class switching by lipopolysaccharide-activated murine B cells occurs predominantly through sequential switching.

  1993cites this paper
• Recognition of antigen and superantigen by cytotoxic lymphocytes

  1993cites this paper
• V(D)J recombination: signal and coding joint resolution are uncoupled and depend on parallel synapsis of the sites

  1993cites this paper
• Extrathymic development of V alpha 14-positive T cells

  1993cites this paper
• VDJ recombination.

  1992cites this paper
• The human γ/δ+ and α/β+ T cells: A branched pathway of differentiation

  1992cites this paper
• A proposed mechanism for promoter-associated DNA rearrangement events at a variant surface glycoprotein gene expression site

  1992cites this paper
• Heavy chain variable (VH) region diversity generated by VH gene replacement in the progeny of a single precursor cell transformed with a temperature-sensitive mutant of Abelson murine leukemia virus

  1992cites this paper
• Rearrangement and diversification of T-cell receptor delta genes in acute lymphoblastic leukemia.

  1992cites this paper
• Immunoglobulin V gene replacement is caused by the intramolecular DNA deletion mechanism.

  1992cites this paper
• A V(D)J site-specific recombination model involving no compulsory double-stranded break formation at the coding segments.

  1992cites this paper
• A survey of protein‐DNA interaction sites within the murine immunoglobulin heavy chain locus reveals a particularly complex pattern around the DQ52 element

  1992cites this paper
• Sex and the single circle: conjugative transposition

  1992cites this paper
• Assembly of IgH CDR3: mechanism, regulation, and influence on antibody diversity.

  1992cites this paper
• V(D)J recombination in mouse thymocytes: double-strand breaks near T cell receptor delta rearrangement signals.

  1992cites this paper
• Molecular analysis of V(D)J recombination.

  1992cites this paper
• The human gamma/delta + and alpha/beta + T cells: a branched pathway of differentiation.

  1992cites this paper
• Novel excision products of T cell receptor γ gene rearrangements and developmental stage specificity implied by the frequency of nucleotide insertions at signal joints

  1992cites this paper
• V(D)J Recombinase Precursors and Coding Structure of Signal Sequence Directed Rearrangement

  1992cites this paper
• Chimeric gamma-delta signal joints. Implications for the mechanism and regulation of T cell receptor gene rearrangement.

  1991cites this paper
• Avian B-cell development: generation of an immunoglobulin repertoire by gene conversion.

  1991cites this paper
• Reciprocal hybrid joints demonstrate successive V-J rearrangements on the same chromosome in the human TCR gamma locus.

  1991cites this paper
• V gamma 3 T cell receptor rearrangement and expression in the adult thymus.

  1991cites this paper
• Circular DNA resulting from recombination between V-(D)-J joining signals and switch repetitive sequences in mouse thymocytes

  1991influential citation
• Deletions of immunoglobulin C kappa region characterized by the circular excision products in mouse splenocytes

  1991cites this paper
• Control of isotype switching by T cells and cytokines.

  1991cites this paper
• Analysis of immunoglobulin and T cell receptor genes. Part I: Basic and technical aspects.

  1991cites this paper