Arachidonic acid needed in infant formula when docosahexaenoic acid is present.

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Nutrition reviews

• Publication date

  2016-05-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1093/nutrit/nuw007PMID 27013482
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Long chain polyunsaturated fatty acid supplementation in infants born at term.

  2017cited by this paper
• Hydroxytyrosol prevents reduction in liver activity of Δ-5 and Δ-6 desaturases, oxidative stress, and depletion in long chain polyunsaturated fatty acid content in different tissues of high-fat diet fed mice

  2017cited by this paper
• Effects of different arachidonic acid supplementation on psychomotor development in very preterm infants; a randomized controlled trial

  2015cited by this paper
• Marine omega-3 fatty acids and inflammatory processes: Effects, mechanisms and clinical relevance.

  2015cited by this paper
• The European Food Safety Authority recommendation for polyunsaturated fatty acid composition of infant formula overrules breast milk, puts infants at risk, and should be revised.

  2015cited by this paper
• The Pattern of Fatty Acids Displaced by EPA and DHA Following 12 Months Supplementation Varies between Blood Cell and Plasma Fractions

  2015cited by this paper
• Should Infant Formula Provide Both Omega-3 DHA and Omega-6 Arachidonic Acid?

  2015cited by this paper
• Dietary arachidonic acid in perinatal nutrition: a commentary

  2015cited by this paper
• Scientific opinion on the essential composition of infant and follow-on formulae.

  2014cited by this paper
• Metabolic Conversion of C20 Polymethylene-Interrupted Polyunsaturated Fatty Acids to Essential Fatty Acids

  2014cited by this paper
• Docosahexaenoic acid synthesis from alpha-linolenic acid is inhibited by diets high in polyunsaturated fatty acids.

  2013cited by this paper
• Regular consumption of Nile river fish could ameliorate the low milk DHA of Southern Sudanese women living in Khartoum City area.

  2013cited by this paper
• Comparative evaluation of xenobiotics in human and dietary milk: persistent organic pollutants and mycotoxins.

  2013cited by this paper
• The low levels of eicosapentaenoic acid in rat brain phospholipids are maintained via multiple redundant mechanisms

  2013cited by this paper
• Omega 3 fatty acids on child growth, visual acuity and neurodevelopment

  2012cited by this paper
• Prolonging the female reproductive lifespan and improving egg quality with dietary omega‐3 fatty acids

  2012cited by this paper
• Animal studies of the functional consequences of suboptimal polyunsaturated fatty acid status during pregnancy, lactation and early post-natal life.

  2011cited by this paper
• Changes in consumption of omega-3 and omega-6 fatty acids in the United States during the 20th century.

  2011cited by this paper
• Long-chain polyunsaturated fatty acid supplementation in infants born at term.

  2011cited by this paper
• Lipoxygenases Mediate the Effect of Essential Fatty Acid in Skin Barrier Formation

  2011cited by this paper
• Milk of northern Sudanese mothers whose traditional diet is high in carbohydrate contains low docosahexaenoic acid

  2010cited by this paper
• Background Paper on Fat and Fatty Acid Requirements during Pregnancy and Lactation

  2009cited by this paper
• Three randomized controlled trials of early long-chain polyunsaturated Fatty Acid supplementation on means-end problem solving in 9-month-olds.

  2009cited by this paper
• Disruption of FADS2 gene in mice impairs male reproduction and causes dermal and intestinal ulceration

  2009cited by this paper
• Toward optimizing vision and cognition in term infants by dietary docosahexaenoic and arachidonic acid supplementation: a review of randomized controlled trials.

  2009cited by this paper
• Synthesis of long-chain polyunsaturated fatty acids in preterm newborns fed formula with long-chain polyunsaturated fatty acids.

  2007cited by this paper
• Docosahexaenoic and arachidonic acid concentrations in human breast milk worldwide.

  2007cited by this paper
• Visual acuity and cognitive outcomes at 4 years of age in a double-blind, randomized trial of long-chain polyunsaturated fatty acid-supplemented infant formula.

  2007cited by this paper
• n-6 fatty acid metabolism in the newborn infant: is linoleic acid sufficient to meet the demand for arachidonic acid?

  2007cited by this paper
• Human milk fatty acid composition from nine countries varies most in DHA

  2006cited by this paper
• Supplementation of infant formula with long-chain polyunsaturated fatty acids does not influence the growth of term infants.

  2005cited by this paper
• Duration of long-chain polyunsaturated fatty acids availability in the diet and visual acuity.

  2005cited by this paper
• Dietary PUFA for Preterm and Term Infants: Review of Clinical Studies

  2005cited by this paper
• Formula feeding potentiates docosahexaenoic and arachidonic acid biosynthesis in term and preterm baboon neonates Published, JLR Papers in Press, October 1, 2003. DOI 10.1194/jlr.M300106-JLR200

  2004cited by this paper
• Increased plasma homocysteine and S-adenosylhomocysteine and decreased methionine is associated with altered phosphatidylcholine and phosphatidylethanolamine in cystic fibrosis.

  2003cited by this paper
• Term infant studies of DHA and ARA supplementation on neurodevelopment: results of randomized controlled trials.

  2003cited by this paper
• Problems with essential fatty acids: time for a new paradigm?

  2003cited by this paper
• Influence of dietary long-chain PUFA on premature baboon lung FA and dipalmitoyl PC composition

  2003cited by this paper
• Visual, cognitive, and language assessments at 39 months: a follow-up study of children fed formulas containing long-chain polyunsaturated fatty acids to 1 year of age.

  2003cited by this paper
• Efficacy of Dietary Arachidonic Acid Provided as Triglyceride or Phospholipid as Substrates for Brain Arachidonic Acid Accretion in Baboon Neonates

  2002cited by this paper
• Efficiency of conversion of alpha-linolenic acid to long chain n-3 fatty acids in man.

  2002cited by this paper
• Efficiency of conversion of alpha-linolenic acid to long chain n-3 fatty acids in man.

  2002cited by this paper
• Significant utilization of dietary arachidonic acid is for brain adrenic acid in baboon neonates.

  2002cited by this paper
• The relationship between age and the fatty acid composition of cerebral cortex and erythrocytes in human subjects.

  2001cited by this paper
• Randomized trials with polyunsaturated fatty acid interventions in preterm and term infants: Functional and clinical outcomes

  2001cited by this paper
• Fetal baboons convert 18:3n-3 to 22:6n-3 in vivo. A stable isotope tracer study.

  2001cited by this paper
• A Critical Appraisal of the Role of Dietary Long-Chain Polyunsaturated Fatty Acids on Neural Indices of Term Infants: A Randomized, Controlled Trial

  2000cited by this paper
• Impact of Early Dietary Intake and Blood Lipid Composition of Long-Chain Polyunsaturated Fatty Acids on Later Visual Development

  2000cited by this paper
• Long Chain Polyunsaturated Fatty Acid Formation in Neonates: Effect of Gestational Age and Intrauterine Growth

  2000cited by this paper
• Breast milk docosahexaenoic acid (DHA) correlates with DHA status of malnourished infants

  2000cited by this paper
• A randomized controlled trial of early dietary supply of long‐chain polyunsaturated fatty acids and mental development in term infants

  2000cited by this paper
• Linoleic acid kinetics and conversion to arachidonic acid in the pregnant and fetal baboon.

  1999cited by this paper
• Bioequivalence of Dietary α-Linolenic and Docosahexaenoic Acids as Sources of Docosahexaenoate Accretion in Brain and Associated Organs of Neonatal Baboons

  1999cited by this paper
• Dietary Long-Chain Polyunsaturated Fatty Acids Do Not Influence Growth of Term Infants: A Randomized Clinical Trial

  1999cited by this paper
• Visual Acuity and the Essentiality of Docosahexaenoic Acid and Arachidonic Acid in the Diet of Term Infants

  1998cited by this paper
• The slow discovery of the importance of omega 3 essential fatty acids in human health.

  1998cited by this paper
• Formula Supplementation With Long-chain Polyunsaturated Fatty Acids: Are There Developmental Benefits?

  1998cited by this paper
• Visual Acuity, Erythrocyte Fatty Acid Composition, and Growth in Term Infants Fed Formulas with Long Chain Polyunsaturated Fatty Acids for One Year

  1997cited by this paper
• Dietary fish oil alters rat milk composition and liver and brain fatty acid composition of fetal and neonatal rats.

  1993cited by this paper
• Arachidonic acid status correlates with first year growth in preterm infants.

  1993cited by this paper
• Tissue levels of polyunsaturated fatty acids during early human development.

  1992cited by this paper
• Apparent in vivo retroconversion of dietary arachidonic to linoleic acid in essential fatty acid-deficient rats.

  1986cited by this paper
• Essential function of linoleic acid esterified in acylglucosylceramide and acylceramide in maintaining the epidermal water permeability barrier. Evidence from feeding studies with oleate, linoleate, arachidonate, columbinate and alpha-linolenate.

  1985cited by this paper
• Extrauterine fatty acid accretion in infant brain: implications for fatty acid requirements.

  1980cited by this paper
• Comparative aspects of the brain growth spurt.

  1979cited by this paper
• ROLE OF LINOLEIC ACID IN INFANT NUTRITION Clinical and Chemical Study of 428 Infants Fed on Milk Mixtures Varying in Kind and Amount of Fat

  1963cited by this paper
• Biological standardization of essential fatty acids; a new method.

  1953cited by this paper

• Association of erythrocyte fatty acid profiles with the presence and rupture of intracranial aneurysms

  2026cites this paper
• Food and Drug Administration Expert Panel on Infant Formula "Operation Stork Speed" June 2025: Part 1, Nutrient Considerations.

  2026cites this paper
• Omega-3 and omega-6 polyunsaturated fatty acids in neurodevelopment and prematurity: Correcting imbalances and closing the Preterm PUFA Gap.

  2026cites this paper
• Enzymatic Degumming of Arachidonic Acid Oil Using Immobilized Phospholipase A1 on Hollow Double-Layer Mesoporous Silica Nanoparticles

  2026cites this paper
• Development and application of synthetic biology tools for improved production of human breast milk components

  2025cites this paper
• Comparative analysis of morphological characteristics and nutritional quality in wild-caught and pond-reared female mud crab, Scylla paramamosain

  2025cites this paper
• Essential fatty acid deficiency, olive oil‐based intravenous lipid emulsion, and genetic polymorphisms: A pediatric randomized controlled trial

  2025cites this paper
• The effect of fish oil versus krill oil intervention on clinical symptoms and cardiometabolic risk factors in patients with major depressive disorder: A randomized placebo-controlled double-blind trial.

  2025cites this paper
• Metabolic pathway for evaluation of polyunsaturated fatty acids content variation and regulation of its biosynthesis in Paeonia ostii through abscisic acid and ABSCISIC ACID-INSENSITIVE 5 (PoABI5)

  2025cites this paper
• Specific activity of mouse liver desaturases and elongases: Time course effects using n-3 and n-6 PUFA substrates and inhibitory responses of delta-6 desaturase.

  2025cites this paper
• Genetic evaluation of nutritional traits in Malabar red snapper (Lutjanus malabaricus): Heritability and genetic correlations of fatty acid composition

  2025cites this paper
• Effect of oil blends with near equal increases in 18 carbon n-3 and n-6 fatty acids on fatty acid profile of eggs

  2025cites this paper
• Emerging insect-based aquafeed for sustainable African catfish production

  2025cites this paper
• The Effect of Consuming Diets Containing Beef Compared with Plant-Based Beef Substitute on Human Milk Composition in the Study of nUtrition in Postpartum and EaRly life (SUPER) Randomized Crossover Feeding Trial.

  2025cites this paper
• Ginsenoside Rk3 Ameliorates Obesity-Induced Colitis by Modulating Lipid Metabolism in C57BL/6 Mice.

  2024cites this paper
• High-throughput optimization of organic carbon provision strategies enables enhanced arachidonic acid production in novel microalgae

  2024cites this paper
• Recent advances on the physiological and pathophysiological roles of polyunsaturated fatty acids and their biosynthetic pathway.

  2024cites this paper
• Effects of dietary L-tryptophan supplementation on agonistic behavior, feeding behavior, growth performance, and nutritional composition of the Chinese mitten crab (Eriocheir sinensis)

  2024cites this paper
• SpecLipIDA: a pseudotargeted lipidomics approach for polyunsaturated fatty acids in milk.

  2024cites this paper
• Docosahexaenoic Acid in Formulas for Term Infants: The Way from Pioneer Idea to Mandatory Dietary Recommendation

  2023cites this paper
• Enteral long-chain polyunsaturated fatty acids and necrotizing enterocolitis: A systematic review and meta-analysis.

  2023cites this paper
• Dietary Fatty Acids and Inflammation: Focus on the n-6 Series

  2023cites this paper
• The imperative of arachidonic acid in human reproduction.

  2023cites this paper
• Important roles of linoleic acid and α-linolenic acid in regulating cognitive impairment and neuropsychiatric issues in metabolic-related dementia.

  2023cites this paper
• Arachidonic acid: reconciling the dichotomy of its oxidative cascade through specific deuteration

  2023cites this paper
• Alpha-Linolenic Acid and Cardiovascular Events: A Narrative Review

  2023cites this paper
• Effects of different stocking densities on growth performance, nutritional quality and economic benefit of juvenile female Chinese mitten crab (Eriocheir sinensis) in rice-crab culture systems

  2022cites this paper
• Effects of involuntary treadmill running in combination with swimming on adult neurogenesis in an Alzheimer's mouse model.

  2022cites this paper
• Docosahexaenoic acid and arachidonic acid levels are correlated in human milk: Implications for new European infant formula regulations.

  2022cites this paper
• Futuristic food fortification with a balanced ratio of dietary ω-3/ω-6 omega fatty acids for the prevention of lifestyle diseases

  2022cites this paper
• Trash fish facilitates protection against the deterioration in nutritional quality of adult female Chinese mitten crabs Eriocheir sinensis during winter

  2022cites this paper
• PRKG1 mutation identified by whole-exome sequencing: a potential genetic etiology for He-Zhao deficiency

  2022cites this paper
• II Consensus of the Brazilian Nutrology Association on DHA recommendations during pregnancy, lactation and childhood

  2022cites this paper
• Breast Milk Lipidome Is Associated With Maternal Diet and Infants' Growth

  2022cites this paper
• Role of 2.4 GHz radiofrequency radiation emitted from Wi-Fi on some miRNA and faty acids composition in brain

  2022cites this paper
• Biochemical composition and quality of wild-caught adult mitten crabs from three river basins

  2022cites this paper
• Heterotrophic Properties of Myrmecia incisa and Strategies for Enhanced Arachidonic Acid Production

  2022cites this paper
• Docosahexaenoic acid-rich algae oil supplementation on breast milk fatty acid profile of mothers who delivered prematurely: a randomized clinical trial

  2021cites this paper
• Research advances on arachidonic acid production by fermentation and genetic modification of Mortierella alpina

  2021cites this paper
• Docosahexaenoic and Arachidonic Acids as Neuroprotective Nutrients throughout the Life Cycle

  2021cites this paper
• Cholesterol Content, Fatty Acid Profile and Health Lipid Indices in the Egg Yolk of Eggs from Hens at the End of the Laying Cycle, Following Alpha-Ketoglutarate Supplementation

  2021cites this paper
• Perspective: Moving Toward Desirable Linoleic Acid Content in Infant Formula

  2021cites this paper
• [Controversy about the critical role of long-chain polyunsaturated fatty acids, arachidonic acid (ARA) and docosahexaenoic acid (DHA), during infancy].

  2021influential citation
• Ovarian fullness affects biochemical composition and nutritional quality of female swimming crab Portunus trituberculatus

  2021cites this paper
• The Role of Adequate Nutrition on Early Stages of Child Development. New Aspects of Goat Milk-Based Infant Formulas Implementation

  2021cites this paper
• Le nouveau cadre réglementaire européen pour les préparations infantiles : commentaires du Comité de nutrition de la Société française de pédiatrie

  2020cites this paper
• ARA or no ARA in infant formulae, that is the question.

  2020cites this paper
• The new European regulatory framework for infant and follow-on formulas: Comments from the Committee of Nutrition of the French Society of Pediatrics (CN-SFP).

  2020cites this paper
• Determination and comparison of phospholipid profiles in eggs from seven different species using UHPLC-ESI-Triple TOF-MS.

  2020cites this paper
• Growth performance, gonad development and nutritional composition of Chinese mitten crab Eriocheir sinensis selected for growth and different maturity time

  2020cites this paper
• Sollen Säuglingsnahrungen sowohl Docosahexaensäure als auch Arachidonsäure enthalten?

  2020cites this paper
• Lipids in Infant Formula

  2020cites this paper
• Linoleic acid–good or bad for the brain?

  2020cites this paper
• Effect of one year krill oil supplementation on depressive symptoms and self-esteem of Dutch adolescents: A randomized controlled trial.

  2020cites this paper
• Growth, tolerance, and DHA and ARA status of healthy term infants receiving formula with two different ARA concentrations: Double-blind, randomized, controlled trial.

  2019cites this paper
• Factors associated with plasma n-3 and n-6 polyunsaturated fatty acid levels in Tanzanian infants

  2019cites this paper
• Human milk fat substitutes: Past achievements and current trends.

  2019cites this paper
• Dietary linoleic acid and human health: Focus on cardiovascular and cardiometabolic effects.

  2019cites this paper
• Human milk fatty acid profile across lactational stages after term and preterm delivery: A pooled data analysis.

  2019cites this paper
• Should formula for infants provide arachidonic acid along with DHA? A position paper of the European Academy of Paediatrics and the Child Health Foundation.

  2019cites this paper
• Infant growth, neurodevelopment and gut microbiota during infancy: which nutrients are crucial?

  2019cites this paper
• Dietary intake of n-3 and n-6 polyunsaturated fatty acids in Korean toddlers 12–24 months of age with comparison to the dietary recommendations

  2019cites this paper
• Efficacy of novel small-quantity lipid-based nutrient supplements in improving long-chain polyunsaturated fatty acid status of South African infants: a randomised controlled trial

  2019cites this paper
• Ultrasound-mediated interfacial protein adsorption and fat crystallization in cholesterol-reduced lard emulsion.

  2019cites this paper
• Developmental Accretion of Docosahexaenoic Acid Is Independent of Fatty Acid Transporter Expression in Brain and Lung Tissues of C57BL/6 and Fat1 Mice.

  2019cites this paper
• International Society for the Study of Fatty Acids and Lipids 2018 Symposium: Arachidonic and Docosahexaenoic Acids in Infant Development

  2019cites this paper
• Children With Intestinal Failure Undergoing Intestinal Rehabilitation Are at Risk for Essential Fatty Acid Deficiency

  2018cites this paper
• Randomized controlled trial of brain specific fatty acid supplementation in pregnant women increases brain volumes on MRI scans of their newborn infants.

  2018cites this paper
• DHA and ARA addition to infant formula: Current status and future research directions.

  2018cites this paper
• The importance of dietary DHA and ARA in early life: a public health perspective

  2017cites this paper
• Microbial Production of Fatty Acids

  2017cites this paper
• Chapter 26: Infant Nutrition and Special Nutritional Needs of Children

  2017cites this paper
• Dietary Intakes of Arachidonic Acid and Docosahexaenoic Acid in Early Life - With a Special Focus on Complementary Feeding in Developing Countries

  2017cites this paper
• Lipids in human milk.

  2017cites this paper
• Breastfeeding, Polyunsaturated Fatty Acid Levels in Colostrum and Child Intelligence Quotient at Age 5‐6 Years

  2017cites this paper
• Fatty acid requirements for the preterm infant.

  2017cites this paper
• The essentiality of arachidonic acid in addition to docosahexaenoic acid for brain growth and function.

  2017cites this paper
• Effects of maternal omega-3 fatty acids supplementation during pregnancy/lactation on body composition of the offspring: A systematic review and meta-analysis.

  2017cites this paper
• Smog induces oxidative stress and microbiota disruption

  2017cites this paper
• Systematic Review on N-3 and N-6 Polyunsaturated Fatty Acid Intake in European Countries in Light of the Current Recommendations - Focus on Specific Population Groups

  2017cites this paper
• Hydroxytyrosol prevents reduction in liver activity of Δ-5 and Δ-6 desaturases, oxidative stress, and depletion in long chain polyunsaturated fatty acid content in different tissues of high-fat diet fed mice

  2017cites this paper
• Effects of arachidonic acid, eicosapentaenoic acid and docosahexaenoic acid on brain development using artificial rearing of delta-6-desaturase knockout mice.

  2017cites this paper
• Determination and Comparison of Phospholipid Profiles in Seven Kinds of Egg Types Using UHPLC-ESI-Q-TOF-MS

  year unknowncites this paper
• Quantitative genetic analysis indicate non-heritability of major fatty acid in the muscle of Chinese mitten crab (Eriocheir sinensis)

  year unknowncites this paper