Nonequilibrium Energetics of Molecular Motor Kinesin.

Nonequilibrium energetics of single molecule translational motor kinesin was investigated by measuring heat dissipation from the violation of the fluctuation-response relation of a probe attached to the motor using optical tweezers. The sum of the dissipation and work did not amount to the input free energy change, indicating large hidden dissipation exists. Possible sources of the hidden dissipation were explored by analyzing the Langevin dynamics of the probe, which incorporates the two-state Markov stepper as a kinesin model. We conclude that internal dissipation is dominant.

• Publication year

  2017

• Venue

  Physical Review Letters

• Publication date

  2017-04-18

• Fields of study

  Biology, Medicine, Physics

• Identifiers
  DOI 10.1016/j.bpj.2017.11.2783arXiv 1704.05302PMID 30517811
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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