Role of the JAK-STAT pathway in myocardial injury.

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Trends in Molecular Medicine

• Publication date

  2007-02-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/J.MOLMED.2006.12.002PMID 17194625
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Signal transducer and activator of transcription 1 activation in endothelial cells is a negative regulator of angiogenesis.

  2006cited by this paper
• Acetylation of Stat1 modulates NF-B activity

  2006cited by this paper
• Innate Defense Mechanism Against Virus Infection Within the Cardiac Myocyte Requiring gp130-STAT3 Signaling

  2006cited by this paper
• Acetylation of Stat1 modulates NF-kappaB activity.

  2006cited by this paper
• Neuroprotective Effect of Recombinant Human Granulocyte Colony-Stimulating Factor in Transient Focal Ischemia of Mice

  2006cited by this paper
• A Novel Platinum Compound Inhibits Constitutive Stat3 Signaling and Induces Cell Cycle Arrest and Apoptosis of Malignant Cells*

  2005cited by this paper
• Role of Stat3 in Regulating p53 Expression and Function

  2005cited by this paper
• G-CSF prevents cardiac remodeling after myocardial infarction by activating the Jak-Stat pathway in cardiomyocytes

  2005cited by this paper
• Pharmacological Preconditioning With Tumor Necrosis Factor-α Activates Signal Transducer and Activator of Transcription-3 at Reperfusion Without Involving Classic Prosurvival Kinases (Akt and Extracellular Signal–Regulated Kinase)

  2005cited by this paper
• Signal Transducer and Activator of Transcription 3α and Specificity Protein 1 Interact to Upregulate Intercellular Adhesion Molecule-1 in Ischemic–Reperfused Myocardium and Vascular Endothelium

  2005cited by this paper
• STAT3 mediates cardioprotection against ischemia/reperfusion injury through metallothionein induction in the heart.

  2005cited by this paper
• Implications of an antiparallel dimeric structure of nonphosphorylated STAT1 for the activation-inactivation cycle.

  2005cited by this paper
• Indirubin derivatives inhibit Stat3 signaling and induce apoptosis in human cancer cells

  2005cited by this paper
• Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity

  2005cited by this paper
• Carbon Monoxide Differentially Modulates STAT1 and STAT3 and Inhibits Apoptosis via a Phosphatidylinositol 3-Kinase/Akt and p38 Kinase-dependent STAT3 Pathway during Anoxia-Reoxygenation Injury*

  2005cited by this paper
• Reduced STAT3 activity in mice mimics clinical disease syndromes.

  2005cited by this paper
• Role of the Protein Kinase C-&egr;–Raf-1–MEK-1/2–p44/42 MAPK Signaling Cascade in the Activation of Signal Transducers and Activators of Transcription 1 and 3 and Induction of Cyclooxygenase-2 After Ischemic Preconditioning

  2005cited by this paper
• Role of apoptosis in reperfusion injury.

  2004cited by this paper
• Vitamin C inhibits hypoxia-induced damage and apoptotic signaling pathways in cardiomyocytes and ischemic hearts.

  2004cited by this paper
• Hypertrophy of the heart: a new therapeutic target?

  2004cited by this paper
• Genetic depletion of cardiac myocyte STAT-3 abolishes classical preconditioning.

  2004cited by this paper
• IL-6 plays an obligatory role in late preconditioning via JAK-STAT signaling and upregulation of iNOS and COX-2.

  2004cited by this paper
• Nucleocytoplasmic shuttling of STAT transcription factors.

  2004cited by this paper
• Epigallocatechin‐3‐gallate inhibits STAT‐1 activation and protects cardiac myocytes from ischemia/reperfusion‐ induced apoptosis

  2004cited by this paper
• Alternative Activation of STAT1 and STAT3 in Response to Interferon-γ*

  2004cited by this paper
• Oxidative stress-elicited myocardial apoptosis during reperfusion.

  2004cited by this paper
• Signal Transducer and Activator of Transcription 3 Is Required for Myocardial Capillary Growth, Control of Interstitial Matrix Deposition, and Heart Protection From Ischemic Injury

  2004cited by this paper
• Essential Role of STAT3 in Postnatal Survival and Growth Revealed by Mice Lacking STAT3 Serine 727 Phosphorylation

  2004cited by this paper
• Inhibition of constitutive signal transducer and activator of transcription 3 activation by novel platinum complexes with potent antitumor activity.

  2004cited by this paper
• A mechanistic role for cardiac myocyte apoptosis in heart failure.

  2003cited by this paper
• The suppressor of cytokine signaling-1 (SOCS1) is a novel therapeutic target for enterovirus-induced cardiac injury.

  2003cited by this paper
• Nuclear Translocation of Phosphorylated STAT3 Is Essential for Vascular Endothelial Growth Factor-induced Human Dermal Microvascular Endothelial Cell Migration and Tube Formation*

  2003cited by this paper
• Phosphorylation of the Stat1 transactivation domain is required for full-fledged IFN-gamma-dependent innate immunity.

  2003cited by this paper
• Alterations in Janus Kinase (JAK)-Signal Transducers and Activators of Transcription (STAT) Signaling in Patients With End-Stage Dilated Cardiomyopathy

  2003cited by this paper
• Stat3 protects against Fas-induced liver injury by redox-dependent and -independent mechanisms.

  2003cited by this paper
• Mechanism of cyclooxygenase-2 upregulation in late preconditioning.

  2003cited by this paper
• Parvovirus B19 Infection Mimicking Acute Myocardial Infarction

  2003cited by this paper
• Human cardiomyocyte hypertrophy induced in vitro by gp130 stimulation.

  2003cited by this paper
• DNA binding controls inactivation and nuclear accumulation of the transcription factor Stat1.

  2003cited by this paper
• STAT1 is Activated in Neurons after Ischemia and Contributes to Ischemic Brain Injury

  2002cited by this paper
• p38 MAPK enhances STAT1-dependent transcription independently of Ser-727 phosphorylation

  2002cited by this paper
• Protein kinase C-delta (PKC-delta ) is activated by type I interferons and mediates phosphorylation of Stat1 on serine 727.

  2002cited by this paper
• Apoptotic pathway activation from mitochondria and death receptors without caspase-3 cleavage in failing human myocardium: fragile balance of myocyte survival?

  2002cited by this paper
• Cardiac-specific Activation of Signal Transducer and Activator of Transcription 3 Promotes Vascular Formation in the Heart*

  2002cited by this paper
• Cytokine signaling in 2002: new surprises in the Jak/Stat pathway.

  2002cited by this paper
• Classic ischemic but not pharmacologic preconditioning is abrogated following genetic ablation of the TNFalpha gene.

  2002cited by this paper
• Signalling: STATs: transcriptional control and biological impact

  2002cited by this paper
• Requirement of Ca2+ and CaMKII for Stat1 Ser-727 phosphorylation in response to IFN-γ

  2002cited by this paper
• Mutational switch of an IL-6 response to an interferon-γ-like response

  2002cited by this paper
• Mutational switch of an IL-6 response to an interferon-gamma-like response.

  2002cited by this paper
• The C‐terminal activation domain of the STAT‐1 transcription enhances ischemia/reperfusion‐induced apoptosis in cardiac myocytes

  2002cited by this paper
• Protein Kinase C-δ (PKC-δ) Is Activated by Type I Interferons and Mediates Phosphorylation of Stat1 on Serine 727*

  2002cited by this paper
• An essential role of the JAK-STAT pathway in ischemic preconditioning

  2001cited by this paper
• Suppressor of cytokine signaling-3 is a biomechanical stress-inducible gene that suppresses gp130-mediated cardiac myocyte hypertrophy and survival pathways.

  2001cited by this paper
• Constitutively activated Stat3 protects fibroblasts from serum withdrawal and UV-induced apoptosis and antagonizes the proapoptotic effects of activated Stat1.

  2001cited by this paper
• Activation of Signal Transducer and Activator of Transcription 3 Protects Cardiomyocytes from Hypoxia/Reoxygenation-Induced Oxidative Stress Through the Upregulation of Manganese Superoxide Dismutase

  2001cited by this paper
• Role of STAT3 in ischemic preconditioning.

  2001cited by this paper
• Signal transducer and activator of transcription 3 in the heart transduces not only a hypertrophic signal but a protective signal against doxorubicin-induced cardiomyopathy.

  2000cited by this paper
• Ischemia-induced STAT-1 Expression and Activation Play a Critical Role in Cardiomyocyte Apoptosis*

  2000cited by this paper
• Signal Transducer and Activator of Transcription 3 Is Required for Glycoprotein 130-mediated Induction of Vascular Endothelial Growth Factor in Cardiac Myocytes*

  2000cited by this paper
• Caspase inhibition and limitation of myocardial infarct size: protection against lethal reperfusion injury

  2000cited by this paper
• Stat1 as a Component of Tumor Necrosis Factor Alpha Receptor 1-TRADD Signaling Complex To Inhibit NF-κB Activation

  2000cited by this paper
• Interleukin-6-induced STAT3 transactivation and Ser727 phosphorylation involves Vav, Rac-1 and the kinase SEK-1/MKK-4 as signal transduction components.

  2000cited by this paper
• Apoptosis and heart failure: A critical review of the literature.

  2000cited by this paper
• Activation of JAK/STAT pathway transduces cytoprotective signal in rat acute myocardial infarction.

  2000cited by this paper
• Stress-induced phosphorylation of STAT1 at Ser727 requires p38 mitogen-activated protein kinase whereas IFN-gamma uses a different signaling pathway.

  1999cited by this paper
• Mechanical stretch activates the JAK/STAT pathway in rat cardiomyocytes.

  1999cited by this paper
• Loss of a gp130 cardiac muscle cell survival pathway is a critical event in the onset of heart failure during biomechanical stress.

  1999cited by this paper
• Regulation of bcl-2 family proteins during development and in response to oxidative stress in cardiac myocytes: association with changes in mitochondrial membrane potential.

  1999cited by this paper
• Stat3 as an oncogene.

  1999cited by this paper
• Apoptosis in heart failure: release of cytochrome c from mitochondria and activation of caspase-3 in human cardiomyopathy.

  1999cited by this paper
• Activation of gp130 transduces hypertrophic signals via STAT3 in cardiac myocytes.

  1998cited by this paper
• Activation of the STAT signaling pathway can cause expression of caspase 1 and apoptosis

  1997cited by this paper
• Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality.

  1997cited by this paper
• Continuous activation of gp130, a signal-transducing receptor component for interleukin 6-related cytokines, causes myocardial hypertrophy in mice.

  1995cited by this paper
• Nuclear Factor- (cid:107) B Plays an Essential Role in the Late Phase of Ischemic Preconditioning in Conscious Rabbits

  year unknowncited by this paper
• The FASEB Journal • FJ Express Full-Length Article Free radical scavenging inhibits STAT phosphorylation following in vivo ischemia/reperfusion injury

  year unknowncited by this paper

• Imidacloprid exposure in rats induces cardiac inflammatory response through activating TLR4/NF-κB/NLRP3 and JAK/STAT signaling pathways: focus on the berberine-loaded nanoliposomes

  2026cites this paper
• Dapagliflozin mitigates myocardial inflammation and metabolic stress in heart failure through STAT1 inhibition: Evidence from multi-omics analyses and experimental exploration.

  2026cites this paper
• Angiotensin II‐induced phosphorylation of CHK1 at serine‐280 drives cardiac remodelling by direct phosphorylation of JAK1, thus activating JAK1‐STAT signalling in murine cardiomyocytes

  2025cites this paper
• Biotechnological Insights into LncRNA-STAT3 Interactions: A Novel Diagnostic Biomarker for Myocardial Hypertrophy

  2025cites this paper
• Single-Cell Multi-Omics Identifies Specialized Cytotoxic and Migratory CD8+ Effector T Cells in Acute Myocarditis.

  2025cites this paper
• Ultrasound-Enhanced Delivery of Pterostilbene-Loaded Long-Circulating Solid Lipid Nanoparticles for the Inhibition of IL-6/STAT3 Signaling Pathway in Ovarian Cancer

  2025cites this paper
• IκBζ Promotes Acute Myocardial Infarction via Endonuclear STAT3 Deactivation.

  2025cites this paper
• Mechanistic Research and Therapeutic Advances of the JAK/STAT Signaling Pathway in Myocardial Infarction

  2025cites this paper
• iPSC-derived cardiomyocytes and engineered heart tissues reveal suppressed JAK2/STAT3 signaling in LMNA-related emery-dreifuss muscular dystrophy

  2025cites this paper
• JAK/STAT pathway in myocardial infarction: Crossroads of immune signaling and cardiac remodeling.

  2025cites this paper
• Aerobic Exercise Attenuates Pressure Overload–Induced Myocardial Remodeling and Myocardial Inflammation via Upregulating miR-574-3p in Mice

  2024cites this paper
• The oncogenic mechanisms of the Janus kinase-signal transducer and activator of transcription pathway in digestive tract tumors

  2024cites this paper
• Review of the Protective Mechanism of Curcumin on Cardiovascular Disease

  2024cites this paper
• The Potential Contribution of MyomiRs miR-133a-3p, -133b, and -206 Dysregulation in Cardiovascular Disease Risk

  2024cites this paper
• Mechanisms and Therapeutic Strategies for Myocardial Ischemia-Reperfusion Injury in Diabetic States.

  2024cites this paper
• Recent Insights into Endogenous Mammalian Cardiac Regeneration Post-Myocardial Infarction

  2024cites this paper
• Unveiling the Complexities: Exploring Mechanisms of Anthracycline-induced Cardiotoxicity

  2024cites this paper
• Exploring the molecular mechanism of ginseng against anthracycline-induced cardiotoxicity based on network pharmacology, molecular docking and molecular dynamics simulation

  2024cites this paper
• Therapeutic Potential of Hydrogen Sulfide in Ischemia and Reperfusion Injury

  2024cites this paper
• Molecular Mechanism of Yangshen Maidong Decoction in the Treatment of Chronic Heart Failure based on Network Pharmacology, Molecular Docking, and Molecular Dynamics Simulations

  2024cites this paper
• PRDX6 alleviated heart failure by inhibiting doxorubicin-induced ferroptosis through the JAK2/STAT1 pathway inactivation

  2024cites this paper
• JAK/STAT3 signaling in cardiac fibrosis: a promising therapeutic target

  2024cites this paper
• Regulation of the JAK/STAT signaling pathway: The promising targets for cardiovascular disease.

  2023cites this paper
• A novel machine learning-derived four-gene signature predicts STEMI and post-STEMI heart failure

  2023cites this paper
• Ruxolitinib ameliorated coxsackievirus B3-induced acute viral myocarditis by suppressing the JAK-STAT pathway.

  2023cites this paper
• Pioneering therapies for post-infarction angiogenesis: Insight into molecular mechanisms and preclinical studies.

  2023cites this paper
• Comparative Roles of IL-1, IL-6, IL-10, IL-17, IL-18, 1L-22, IL-33, and IL-37 in Various Cardiovascular Diseases With Potential Insights for Targeted Immunotherapy

  2023cites this paper
• Endogenous interleukin-22 prevents cardiac rupture after myocardial infarction in mice

  2023cites this paper
• Network pharmacology-based approach to explore the underlying mechanism of sinomenine on sepsis-induced myocardial injury in rats

  2023cites this paper
• Lack of STAT1 co-operative DNA binding protects against adverse cardiac remodelling in acute myocardial infarction

  2023cites this paper
• Umbelliferone attenuates diabetic cardiomyopathy by suppression of JAK/STAT signaling pathway through amelioration of oxidative stress and inflammation in rats

  2023cites this paper
• IL-27 promotes cardiac fibroblast activation and aggravates cardiac remodeling post myocardial infarction

  2023cites this paper
• The Role of JAK/STAT Pathway in Fibrotic Diseases: Molecular and Cellular Mechanisms

  2023cites this paper
• Status of the Janus Kinase-Signal Transducer and Activator of Transcription (JAK-STAT) pathway in liver and skin of the freeze tolerant wood frog.

  2022cites this paper
• Type I collagen decorated nanoporous network on titanium implant surface promotes osseointegration through mediating immunomodulation, angiogenesis, and osteogenesis.

  2022cites this paper
• Caspase-mediated regulation of the distinct signaling pathways and mechanisms in neuronal survival.

  2022cites this paper
• Bilateral Superior Cervical Sympathectomy Activates Signal Transducer and Activator of Transcription 3 Signal to Alleviate Myocardial Ischemia-Reperfusion Injury

  2022cites this paper
• Notoginsenoside R1 relieves the myocardial infarction via activating the JAK2/STAT3 signaling pathway in vivo and in vitro

  2022cites this paper
• Signaling pathways and targeted therapy for myocardial infarction

  2022cites this paper
• Radiation-induced cardiovascular disease: an overlooked role for DNA methylation?

  2021cites this paper
• ICT1 Promotes Osteosarcoma Cell Proliferation and Inhibits Apoptosis via STAT3/BCL-2 Pathway

  2021cites this paper
• Regulation of STAT3 and its role in cardioprotection by conditioning: focus on non-genomic roles targeting mitochondrial function

  2021cites this paper
• Reawakening the Intrinsic Cardiac Regenerative Potential: Molecular Strategies to Boost Dedifferentiation and Proliferation of Endogenous Cardiomyocytes

  2021cites this paper
• Empagliflozin protects the heart against ischemia/reperfusion-induced sudden cardiac death

  2021cites this paper
• Hydroxysafflor yellow A, a natural compound from Carthamus tinctorius L with good effect of alleviating atherosclerosis.

  2021cites this paper
• Ginger: A complementary approach for management of cardiovascular diseases

  2021cites this paper
• Downregulation of miR-3568 Protects Against Ischemia/Reperfusion-Induced Cardiac Dysfunction in Rats and Apoptosis in H9C2 Cardiomyocytes Through Targeting TRIM62

  2020cites this paper
• Vagus nerve plays a pivotal role in CD4+ T cell differentiation during CVB3-induced murine acute myocarditis

  2020cites this paper
• Moderate Hydrogen Peroxide Postconditioning Ameliorates Ischemia/Reperfusion Injury in Cardiomyocytes via STAT3-Induced Calcium, ROS, and ATP Homeostasis

  2020cites this paper
• Circular RNA Involved in the Protective Effect of Malva sylvestris L. on Myocardial Ischemic/Re-Perfused Injury

  2020cites this paper
• ADAM8 affects glioblastoma progression by regulating osteopontin-mediated angiogenesis

  2020cites this paper
• Trypanosoma cruzi Promotes Transcriptomic Remodeling of the JAK/STAT Signaling and Cell Cycle Pathways in Myoblasts

  2020influential citation
• Classification, Histopathology, Immunohistology, and Molecular Diagnosis of Myocarditis

  2020cites this paper
• Heart Dysfunction Following Long-Term Murine Cytomegalovirus Infection: Fibrosis, Hypertrophy, and Tachycardia

  2020cites this paper
• Interleukin 35 ameliorates myocardial ischemia‐reperfusion injury by activating the gp130‐STAT3 axis

  2020cites this paper
• EP4 activation ameliorates liver ischemia/reperfusion injury via ERK1/2-GSK3β-dependent MPTP inhibition

  2020cites this paper
• MiR-375 Mediates Chondrocyte Metabolism and Oxidative Stress in Osteoarthritis Mouse Models through the JAK2/STAT3 Signaling Pathway

  2020cites this paper
• MiR-326 targets MDK to regulate the progression of cardiac hypertrophy through blocking JAK/STAT and MAPK signaling pathways.

  2020cites this paper
• The heart of a hibernator: EGFR and MAPK signaling in cardiac muscle during the hibernation of thirteen-lined ground squirrels, Ictidomys tridecemlineatus

  2019cites this paper
• Fibrosis Rescue Improves Cardiac Function in Dystrophin-Deficient Mice and Duchenne Patient-Specific Cardiomyocytes by Immunoproteasome Modulation.

  2019cites this paper
• Curcumin augments the cardioprotective effect of metformin in an experimental model of type I diabetes mellitus; Impact of Nrf2/HO-1 and JAK/STAT pathways.

  2019cites this paper
• Post-Genomic Methodologies and Preclinical Animal Models: Chances for the Translation of Cardioprotection to the Clinic

  2019cites this paper
• Janus kinases to jakinibs: from basic insights to clinical practice.

  2019cites this paper
• Urocortin Induces Phosphorylation of Distinct Residues of Signal Transducer and Activator of Transcription 3 (STAT3) via Different Signaling Pathways

  2019cites this paper
• Acylated ghrelin prevents doxorubicin-induced cardiac intrinsic cell death and fibrosis in rats by restoring IL-6/JAK2/STAT3 signaling pathway and inhibition of STAT1

  2019cites this paper
• E3-ubiquitin ligase TRIM6 aggravates myocardial ischemia/reperfusion injury via promoting STAT1-dependent cardiomyocyte apoptosis

  2019cites this paper
• Hydroxysafflor Yellow A mitigated myocardial ischemia/reperfusion injury by inhibiting the activation of the JAK2/STAT1 pathway

  2019cites this paper
• Astragaloside IV reduces cardiomyocyte apoptosis in a murine model of coxsackievirus B3-induced viral myocarditis

  2019cites this paper
• Effects of propofol on myocardial ischemia reperfusion injury through inhibiting the JAK/STAT pathway.

  2019cites this paper
• Systems Network Genomic Analysis Reveals Cardioprotective Effect of MURC/Cavin‐4 Deletion Against Ischemia/Reperfusion Injury

  2019cites this paper
• Reduces Cardiomyocyte Apoptosis in a Murine Model of Coxsackievirus B 3-induced Viral Myocarditis

  2019cites this paper
• Cardioprotection of post-ischemic moderate ROS against ischemia/reperfusion via STAT3-induced the inhibition of MCU opening

  2019cites this paper
• Calycosin-7-O-β-d-glucoside attenuates myocardial ischemia–reperfusion injury by activating JAK2/STAT3 signaling pathway via the regulation of IL-10 secretion in mice

  2019cites this paper
• The competitive nature of signal transducer and activator of transcription complex formation drives phenotype switching of T cells

  2018cites this paper
• Cardioprotective effect of ghrelin against myocardial infarction-induced left ventricular injury via inhibition of SOCS3 and activation of JAK2/STAT3 signaling

  2018cites this paper
• Strategies to increase cardioprotection through cardioprotective chemokines in chemotherapy-induced cardiotoxicity.

  2018cites this paper
• Cholinergic and cytoprotective signaling cascades mediate the mitigative effect of erythropoietin on acute radiation syndrome.

  2018cites this paper
• Conditioning-induced cardioprotection: Aging as a confounding factor

  2018cites this paper
• Signaling mediators modulated by cardioprotective interventions in healthy and diabetic myocardium with ischaemia–reperfusion injury

  2018cites this paper
• Novel Insights into the Pathophysiology of Chagas' Cardiomyopathy

  2017cites this paper
• Sevoflurane postconditioning protects the myocardium against ischemia/reperfusion injury via activation of the JAK2–STAT3 pathway

  2017cites this paper
• Salidroside protects rat liver against ischemia/reperfusion injury by regulating the GSK‐3&bgr;/Nrf2‐dependent antioxidant response and mitochondrial permeability transition

  2017cites this paper
• Propofol postconditioning attenuates hippocampus ischemia-reperfusion injury via modulating JAK2/STAT3 pathway in rats after autogenous orthotropic liver transplantation.

  2017cites this paper
• The competitive nature of STAT complex formation drives phenotype switching of T cells

  2017cites this paper
• Sevoflurane Postconditioning Reduces Apoptosis by Activating the JAK-STAT Pathway After Transient Global Cerebral Ischemia in Rats

  2017cites this paper
• Cardiac overexpression of Epac1 in transgenic mice rescues lipopolysaccharide-induced cardiac dysfunction and inhibits Jak-STAT pathway.

  2017cites this paper
• Knockdown of KLF11 attenuates hypoxia/reoxygenation injury via JAK2/STAT3 signaling in H9c2

  2016cites this paper
• Response of the JAK-STAT pathway to mammalian hibernation in 13-lined ground squirrel striated muscle

  2016influential citation
• JAK2/STAT3 Pathway Mediates Protection of Metallothionein Against Doxorubicin-Induced Cytotoxicity in Mouse Cardiomyocytes

  2016cites this paper
• Epac activation inhibits IL-6-induced cardiac myocyte dysfunction

  2016cites this paper
• Renal Nerve-Mediated Erythropoietin Release Confers Cardioprotection During Remote Ischemic Preconditioning.

  2015cites this paper
• INTERLEUKIN-17: A CARDIAC BIOMARKER IN ESTIMATION OF CARDIOPROTECTIVE EFFECTS OF TACROLIMUS IN DOXORUBICIN-INDUCED CARDIOTOXICITY: ANIMAL MODEL STUDY

  2015cites this paper
• Myocardial Hypertrophic Remodeling and Impaired Left Ventricular Function in Mice with a Cardiac-Specific Deletion of Janus Kinase 2.

  2015cites this paper
• Simvastatin prevents isoproterenol-induced cardiac hypertrophy through modulation of the JAK/STAT pathway

  2015cites this paper
• Regulation of signal transducer and activator of transcription 3 and apoptotic pathways by betaine attenuates isoproterenol-induced acute myocardial injury in rats

  2015cites this paper
• Left Ventricular Mid-Cavity Hypertrophic Cardiomyopathy with Myeloproliferative Neoplasm Leading to Multiple Cerebral Emboli.

  2015cites this paper
• ROS generated during early reperfusion contribute to intermittent hypobaric hypoxia-afforded cardioprotection against postischemia-induced Ca(2+) overload and contractile dysfunction via the JAK2/STAT3 pathway.

  2015influential citation
• Role of alpha-ketoglutarate receptor G-protein coupled receptor 99 (GPR99) in cardiac hypertrophy

  2015cites this paper
• Mathematical Modelling of Inter- and Intracellular Signal Transduction: The Regulatory Role of Multisite Interactions

  2015cites this paper
• The Role of Interleukin-10 Family Members in Inflammatory Skin Diseases. Understanding the mechanism of action of interferon lambda and interleukin-22 on human primary keratinocytes and dermal fibroblasts with a focus on healing responses in inflammatory skin diseases

  2015cites this paper