Inhibition of in vitro low-density lipoprotein oxidation by oligomeric procyanidins present in chocolate and cocoas.

No abstract is available for this paper.

• Publication year

  2001

• Venue

  Methods in Enzymology

• Publication date

  Unknown publication date

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1016/S0076-6879(01)35257-6PMID 11400384
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Cocoa inhibits platelet activation and function.

  2000cited by this paper
• Caffeinated beverages : health benefits, physiological effects, and chemistry

  2000cited by this paper
• Studies in Polyphenol Chemistry and Bioactivity. 1. Preparation of Building Blocks from (+)-Catechin. Procyanidin Formation. Synthesis of the Cancer Cell Growth Inhibitor, 3- O -Galloyl-(2 R ,3 R )-epicatechin-4β,8-[3- O -galloyl-(2 R ,3 R )-epicatechin]

  1999cited by this paper
• Plasma kinetics in man of epicatechin from black chocolate

  1999cited by this paper
• Protection against peroxynitrite by cocoa polyphenol oligomers

  1999cited by this paper
• High-performance liquid Chromatography/Mass spectrometry analysis of proanthocyanidins in foods and beverages.

  1999cited by this paper
• HPLC method for the quantification of procyanidins in cocoa and chocolate samples and correlation to total antioxidant capacity.

  1999cited by this paper
• Identification of procyanidins in cocoa (Theobroma cacao) and chocolate using high-performance liquid chromatography/mass spectrometry.

  1999cited by this paper
• Procyanidins extracted from pine bark protect α‐tocopherol in ECV 304 endothelial cells challenged by activated RAW 264.7 macrophages: role of nitric oxide and peroxynitrite

  1998cited by this paper
• Oxidants and antioxidants in the pathogenesis of atherosclerosis: implications for the oxidized low density lipoprotein hypothesis.

  1998cited by this paper
• Networking antioxidants in the isolated rat heart are selectively depleted by ischemia-reperfusion.

  1998cited by this paper
• Sparing effect of procyanidins from Vitis vinifera on vitamin E: in vitro studies.

  1998cited by this paper
• Fruit Hydroxycinnamic Acids Inhibit Human Low-Density Lipoprotein Oxidation in Vitro

  1998cited by this paper
• Polyphenols in chocolate, which have antioxidant activity, modulate immune functions in humans in vitro.

  1997cited by this paper
• Inhibition of human low-density lipoprotein oxidation by flavonoids in red wine and grape juice.

  1997cited by this paper
• Inhibition of Human Low-Density Lipoprotein Oxidation in Relation to Composition of Phenolic Antioxidants in Grapes (Vitis vinifera)

  1997cited by this paper
• Licorice extract and its major polyphenol glabridin protect low-density lipoprotein against lipid peroxidation: in vitro and ex vivo studies in humans and in atherosclerotic apolipoprotein E-deficient mice.

  1997cited by this paper
• Effect of tea flavonoid supplementation on the susceptibility of low-density lipoprotein to oxidative modification.

  1997cited by this paper
• Antioxidant flavonols and coronary heart disease risk.

  1997cited by this paper
• Reduced progression of atherosclerosis in apolipoprotein E-deficient mice following consumption of red wine, or its polyphenols quercetin or catechin, is associated with reduced susceptibility of LDL to oxidation and aggregation.

  1997cited by this paper
• Dietary flavonoids, antioxidant vitamins, and incidence of stroke: the Zutphen study.

  1996cited by this paper
• Structure-antioxidant activity relationships of flavonoids and phenolic acids.

  1996cited by this paper
• Procyanidines from Vitis vinifera seeds protect rabbit heart from ischemia/reperfusion injury: antioxidant intervention and/or iron and copper sequestering ability.

  1996cited by this paper
• Inhibition of LDL oxidation by cocoa.

  1996cited by this paper
• Antioxidants in chocolate.

  1996cited by this paper
• Dietary Flavonoids, Antioxidant Vitamins, and Incidence of Stroke: The Zutphen Study

  1996cited by this paper
• Inhibition of LDL oxidation by cocoa

  1996cited by this paper
• Polyphenolic flavanols as scavengers of aqueous phase radicals and as chain-breaking antioxidants.

  1995cited by this paper
• Principal Phenolic Phytochemicals in Selected California Wines and Their Antioxidant Activity in Inhibiting Oxidation of Human Low-Density Lipoproteins

  1995cited by this paper
• Plant Flavonoids, Especially Tea Flavonols, Are Powerful Antioxidants Using an in Vitro Oxidation Model for Heart Disease

  1995cited by this paper
• Flavonoid intake and long-term risk of coronary heart disease and cancer in the seven countries study.

  1995cited by this paper
• Comparison of the Inhibitory Effects of Monomeric, Dimeric, and Trimeric Procyanidins on the Biochemical Markers of Skin Tumor Promotion in Mouse Epidermis in vivo

  1994cited by this paper
• The inhibitory effects of tea polyphenols (flavan-3-ol derivatives) on Cu2+ mediated oxidative modification of low density lipoprotein.

  1994cited by this paper
• Mechanisms of copper- and iron-dependent oxidative modification of human low density lipoprotein.

  1993cited by this paper
• Vasodilatory effects of flavonoids in rat aortic smooth muscle. Structure-activity relationships.

  1993cited by this paper
• Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly Study.

  1993cited by this paper
• Synthesis of monohydroxylated fatty acids from linoleic acid by rat aortic smooth muscle cells and tissues: influence on prostacyclin production.

  1993cited by this paper
• Predisposition to LDL oxidation in patients with and without angiographically established coronary artery disease.

  1993cited by this paper
• Susceptibility of low-density lipoproteins to oxidation in coronary bypass patients.

  1992cited by this paper
• Headspace gas chromatography to determine human low density lipoprotein oxidation

  1992cited by this paper
• Oxidative status of lipoproteins in coronary disease patients.

  1992cited by this paper
• Wine, alcohol, platelets, and the French paradox for coronary heart disease

  1992cited by this paper
• Tea consumption. relationship to cholesterol, blood pressure, and coronary and total mortality.

  1992cited by this paper
• The role of lipid peroxidation and antioxidants in oxidative modification of LDL.

  1992cited by this paper
• Susceptibility to low-density lipoprotein oxidation and coronary atherosclerosis in man.

  1992cited by this paper
• The pathogenesis of atherosclerosis: An overview

  1991cited by this paper
• Analyses of fats, oils, and lipoproteins

  1991cited by this paper
• Immunologic aspects of Kawasaki disease: Implications for pathogenesis and therapy

  1991cited by this paper
• Alpha-tocopherol consumption during low-density-lipoprotein oxidation.

  1990cited by this paper
• Activation of soluble guanylate cyclase by nitrovasodilators is inhibited by oxidized low-density lipoprotein.

  1990cited by this paper
• Oxidized low‐density lipoprotein is chemotactic for arterial smooth muscle cells in culture

  1990cited by this paper
• Minimally modified low density lipoprotein stimulates monocyte endothelial interactions.

  1990cited by this paper
• α-tocopherol consumption during low-density-lipoprotein oxidation

  1990cited by this paper
• Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity.

  1989cited by this paper
• Book ReviewAmbulatory Pediatric Care

  1989cited by this paper
• A role for endothelial cell lipoxygenase in the oxidative modification of low density lipoprotein.

  1989cited by this paper
• Chronic antidepressant treatment increases the apomorphine‐induced elevation of plasma corticosterone in rats

  1988cited by this paper
• Screening of the influence of flavonoids on lipoxygenase and cyclooxygenase activity, as well as on nonenzymic lipid oxidation.

  1988cited by this paper
• Oxidatively modified low density lipoproteins: a potential role in recruitment and retention of monocyte/macrophages during atherogenesis.

  1987cited by this paper
• Decrease in Reactive Amino Groups during Oxidation or Endothelial Cell Modification of LDL: Correlation with Changes in Receptor‐Mediated Cataboiism

  1987cited by this paper
• Fruit and vegetable consumption and cardiovascular mortality.

  1985cited by this paper
• Low density lipoprotein cytotoxicity induced by free radical peroxidation of lipid.

  1983cited by this paper
• The role of the monocyte in atherogenesis: I. Transition of blood-borne monocytes into foam cells in fatty lesions.

  1981cited by this paper
• The role of the monocyte in atherogenesis: I. Transition of blood-borne monocytes into foam cells in fatty lesions.

  1981cited by this paper
• The low-density lipoprotein pathway and its relation to atherosclerosis.

  1977cited by this paper
• The flavonoids. A class of semi-essential food components: their role in human nutrition.

  1976cited by this paper
• Protein measurement with the Folin phenol reagent.

  1951cited by this paper

• Cocoa Polyphenol Extract Inhibits Cellular Senescence via Modulation of SIRT1 and SIRT3 in Auditory Cells

  2023cites this paper
• Recent Developments in Procyanidins on Metabolic Diseases, Their Possible Sources, Pharmacokinetic Profile, and Clinical Outcomes

  2022cites this paper
• Study of Lycium Shawii Phenolic Compounds in Treatment of Hyperlipidemia

  2020cites this paper
• Bioassay-guided isolation of proanthocyanidins with antioxidant activity from peanut (Arachis hypogaea) skin by combination of chromatography techniques.

  2016cites this paper
• Anti-Oxidative Polyphenolic Compounds of Cocoa.

  2015cites this paper
• EFFECT OF POLYPHENOL-RICH DARK CHOCOLATE ON ANTHROPOMETRIC, NUTRITIONAL, BIOCHEMICAL AND PHYSIOLOGICAL MARKERS IN NORMAL WEIGHT AND OVERWEIGHT ADULTS

  2014cites this paper
• Etude chimique de colorants naturels et matériaux résineux traditionnels au Bénin dans le domaine artisanal

  2014cites this paper
• Effect of food matrix interaction between dietary fibre and polyphenols on their metabolism by colonic bacteria

  2014cites this paper
• A Systematic Review and Meta-Analysis of the Effects of Pycnogenol on Plasma Lipids

  2014cites this paper
• The effects of cocoa supplementation , c on oxidative stress markers of brain an

  2013cites this paper
• The effects of cocoa supplementation, caloric restriction, and regular exercise, on oxidative stress markers of brain and memory in the rat model.

  2013cites this paper
• 1 Antioxidants and Radical Scavengers

  2012cites this paper
• Biodiversité, bioactivité et biosynthèse des composés terpéniques volatils des lavandes ailées, Lavandula stoechas sensu lato, un complexe d'espèces méditerranéennes d'intérêt pharmacologique

  2012cites this paper
• Characterization of oligomeric procyanidins and identification of quercetin glucuronide from lotus ( Nelumbo nucifera Gaertn.) seedpod.

  2012cites this paper
• Chocolate and Cocoa: A Comprehensive Review on Cardiovascular Benefits

  2012cites this paper
• Procyanidins in fruit from Sour cherry (Prunus cerasus) differ strongly in chainlength from those in Laurel cherry (Prunus lauracerasus) and Cornelian cherry (Cornus mas)

  2011cites this paper
• Effects of Cocoa Extract and Dark Chocolate on Angiotensin-converting Enzyme and Nitric Oxide in Human Endothelial Cells and Healthy Volunteers–A Nutrigenomics Perspective

  2011cites this paper
• Modulation of platelet function and signaling by flavonoids.

  2011cites this paper
• Study of Middle-Aged and Elderly Women Chocolate Intake and Incidence of Heart Failure: A Population-Based, Prospective

  2010cites this paper
• Chocolate Intake and Incidence of Heart Failure: A Population-Based Prospective Study of Middle-Aged and Elderly Women

  2010cites this paper
• Bioavailability and Recent Advances in the Bioactivity of Flavonoid and Stilbene Compounds

  2010cites this paper
• Efficient isolation of major procyanidin A-type dimers from peanut skins and B-type dimers from grape seeds

  2009cites this paper
• Identification of Phenolic Compounds from Peanut Skin using HPLC-MSn

  2009cites this paper
• Rapid preparation of procyanidins B2 and C1 from Granny Smith apples by using low pressure column chromatography and identification of their oligomeric procyanidins.

  2008cites this paper
• Flavanol-Rich Cocoa: A Cardioprotective Nutriceutical

  2008cites this paper
• Effects of long-term administration of a cocoa polyphenolic extract (Acticoa powder) on cognitive performances in aged rats

  2008cites this paper
• Isolation and structure elucidation of procyanidin oligomers from Saskatoon berries (Amelanchier alnifolia).

  2007cites this paper
• Flavanols: digestion, absorption and bioactivity

  2007cites this paper
• A diet rich in dietary fiber from cocoa improves lipid profile and reduces malondialdehyde in hypercholesterolemic rats.

  2007cites this paper
• From the inside out: the Moisturol story could have taken another twist.

  2007cites this paper
• Immune Effects of Cocoa Procyanidin Oligomers on Peripheral Blood Mononuclear Cells

  2007cites this paper
• Unravelling the total antioxidant capacity of pinotage wines: contribution of phenolic compounds.

  2006cites this paper
• Inhibitory Effects of Procyanidin B2 Dimer on Lipid-laden Macrophage Formation

  2006cites this paper
• Identification and Quantification of Flavanols and Methylxanthines in Chocolates with Different Percentages of Chocolate Liquor

  2006cites this paper
• PROMOTION COMMITTEE Fifth meeting London, 8 December 2005 at 3.00 p.m. INVENTORY OF THE HEALTH AND NUTRITIONAL ATTRIBUTES OF COCOA AND CHOCOLATE

  2005cites this paper
• Regular Consumption of a Flavanol-rich Chocolate can Improve Oxidant Stress in Young Soccer Players

  2005cites this paper
• Cocoa antioxidants and cardiovascular health.

  2005cites this paper
• Lipid peroxidation by "free" iron ions and myoglobin as affected by dietary antioxidants in simulated gastric fluids.

  2005cites this paper
• Catechins and procyanidins in berries of vaccinium species and their antioxidant activity.

  2005cites this paper
• Biological Properties of Monomeric and Polymeric Catechins: Green Tea Catechins and Procyanidins

  2004cites this paper
• Pentameric Procyanidins Isolated from Theobroma cacao Seeds Selectively Downregulate ErbB2 in Human Aortic Endothelial Cells

  2004cites this paper
• Characterization and estimation of proanthocyanidins and other phenolics in coffee pulp (Coffea arabica) by thiolysis-high-performance liquid chromatography.

  2004cites this paper
• Major flavonoids in grape seeds and skins: antioxidant capacity of catechin, epicatechin, and gallic acid.

  2004cites this paper
• Cocoa antioxidants and cardiovascular health 1 – 4

  2004cites this paper
• Proanthocyanidins: Biological Activities Associated with Human Health

  2004cites this paper
• Effect of Cocoa and Chocolate Beverage Consumption on Human Cardiovascular Health

  2004cites this paper
• Flavan-3-ols and procyanidins protect liposomes against lipid oxidation and disruption of the bilayer structure.

  2003cites this paper
• Inhibition of angiotensin converting enzyme (ACE) activity by flavan‐3‐ols and procyanidins

  2003cites this paper
• Cocoa Flavonols and Procyanidins Promote Transforming Growth Factor-β1 Homeostasis in Peripheral Blood Mononuclear Cells1

  2003cites this paper
• Dietary flavanols and procyanidin oligomers from cocoa (Theobroma cacao) inhibit platelet function.

  2003cites this paper
• Study of phenolic compounds as natural antioxidants by a fluorescence method.

  2003cites this paper
• Chocolate intake increases urinary excretion of polyphenol-derived phenolic acids in healthy human subjects.

  2003cites this paper
• Flavanol-Rich Foods and Cardiovascular Health

  2003cites this paper
• THE OFFICIAL BULLETIN OF THE INTERNATIONAL ACADEMY OF CARDIOVASCULAR SCIENCES

  2003cites this paper
• Chronic consumption of a flavanol- and procyanindin-rich diet is associated with reduced levels of 8-hydroxy-2'-deoxyguanosine in rat testes.

  2003cites this paper
• Effect of Cocoa Flavanols and Their Related Oligomers on the Secretion of Interleukin-5 in Peripheral Blood Mononuclear Cells

  2002cites this paper
• Cocoa flavanols and cardiovascular health

  2002cites this paper
• Modulation of TNF-α Secretion in Peripheral Blood Mononuclear Cells by Cocoa Flavanols and Procyanidins

  2002cites this paper
• Cocoa procyanidins are stable during gastric transit in humans.

  2002cites this paper
• Inhibitory Effects of Cocoa Flavanols and Procyanidin Oligomers on Free Radical-Induced Erythrocyte Hemolysis

  2002cites this paper
• Procyanidin dimer B2 [epicatechin-(4beta-8)-epicatechin] in human plasma after the consumption of a flavanol-rich cocoa.

  2002cites this paper
• Procyanidin dimer B2 [epicatechin-(4 (cid:2) -8)-epicatechin] in human plasma after the consumption of a flavanol-rich cocoa 1–3

  2002cites this paper
• Influence of flavan-3-ols and procyanidins on UVC-mediated formation of 8-oxo-7,8-dihydro-2'-deoxyguanosine in isolated DNA.

  2002cites this paper
• Cocoa procyanidin chain length does not determine ability to protect LDL from oxidation when monomer units are controlled.

  2002cites this paper
• Chocolate: Food as Medicine/Medicine as Food

  2001cites this paper