The Escherichia coli relBE genes belong to a new toxin–antitoxin gene family

No abstract is available for this paper.

• Publication year

  1998

• Venue

  Molecular Microbiology

• Publication date

  1998-08-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1046/j.1365-2958.1998.00993.xPMID 9767574
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• To be or not to be: the ultimate decision of the growth‐arrested bacterial cell

  1998cited by this paper
• The OxyS regulatory RNA represses rpoS translation and binds the Hfq (HF‐I) protein

  1998cited by this paper
• Antisense RNA-regulated programmed cell death.

  1997cited by this paper
• The complete genome sequence of Escherichia coli K-12.

  1997influential reference
• A new plasmid-encoded proteic killer gene system: cloning, sequencing, and analyzing hig locus of plasmid Rts1.

  1996cited by this paper
• Plasmid RK2 toxin protein ParE: purification and interaction with the ParD antitoxin protein

  1996cited by this paper
• An Escherichia coli chromosomal "addiction module" regulated by guanosine [corrected] 3',5'-bispyrophosphate: a model for programmed bacterial cell death.

  1996cited by this paper
• Programmed cell death in bacteria: proteic plasmid stabilization systems

  1995influential reference
• Whole-genome random sequencing and assembly of Haemophilus influenzae Rd.

  1995cited by this paper
• Addiction protein Phd of plasmid prophage P1 is a substrate of the ClpXP serine protease of Escherichia coli.

  1995cited by this paper
• Kid, a small protein of the parD stability system of plasmid R1, is an inhibitor of DNA replication acting at the initiation of DNA synthesis.

  1995cited by this paper
• Identification of high affinity binding sites for LexA which define new DNA damage-inducible genes in Escherichia coli.

  1994cited by this paper
• Lon‐dependent proteolysis of CcdA is the key control for activation of CcdB in plasmid‐free segregant bacteria

  1994cited by this paper
• The parDE operon of the broad-host-range plasmid RK2 specifies growth inhibition associated with plasmid loss.

  1994cited by this paper
• Partitioning of plasmid R1. Ten direct repeats flanking the parA promoter constitute a centromere-like partition site parC, that expresses incompatibility.

  1994cited by this paper
• chpA and chpB, Escherichia coli chromosomal homologs of the pem locus responsible for stable maintenance of plasmid R100

  1993cited by this paper
• Plasmid addiction genes of bacteriophage P1: doc, which causes cell death on curing of prophage, and phd, which prevents host death when prophage is retained.

  1993cited by this paper
• Nucleotide sequence encoding the mannose-fucose-resistant hemagglutinin of Vibrio cholerae O1 and construction of a mutant

  1993cited by this paper
• The F plasmid CcdB protein induces efficient ATP-dependent DNA cleavage by gyrase.

  1993cited by this paper
• Mechanism of post-segregational killing by the hok/sok system of plasmid R1. Sok antisense RNA regulates hok gene expression indirectly through the overlapping mok gene.

  1992cited by this paper
• The stable maintenance system pem of plasmid R100: degradation of PemI protein may allow PemK protein to inhibit cell growth

  1992cited by this paper
• Cell killing by the F plasmid CcdB protein involves poisoning of DNA-topoisomerase II complexes.

  1992cited by this paper
• The hok killer gene family in gram-negative bacteria.

  1990cited by this paper
• Basic local alignment search tool.

  1990cited by this paper
• Nucleotide sequence and replication characteristics of RepFIB, a basic replicon of IncF plasmids

  1989cited by this paper
• The F plasmid ccd autorepressor is a complex of CcdA and CcdB proteins

  1989cited by this paper
• The nucleotide sequence and characterization of the relA gene of Escherichia coli.

  1988cited by this paper
• Promoters largely determine the efficiency of repressor action.

  1988influential reference
• Two genes, pemK and pemI, responsible for stable maintenance of resistance plasmid R100

  1988cited by this paper
• Identification of components of a new stability system of plasmid R1, ParD, that is close to the origin of replication of this plasmid

  1987cited by this paper
• Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa.

  1987cited by this paper
• Partitioning of plasmid R1. Structural and functional analysis of the parA locus.

  1986cited by this paper
• Mechanism of postsegregational killing by the hok gene product of the parB system of plasmid R1 and its homology with the relF gene product of the E. coli relB operon.

  1986cited by this paper
• Unique type of plasmid maintenance function: postsegregational killing of plasmid-free cells.

  1986cited by this paper
• Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC19 vectors.

  1985cited by this paper
• A versatile multiple- and single-copy vector system for the in vitro construction of transcriptional fusions to lacZ.

  1985cited by this paper
• Sequence of the relB transcription unit from Escherichia coli and identification of the relB gene.

  1985influential reference
• Stable inheritance of plasmid R1 requires two different loci

  1985cited by this paper
• Mini-F plasmid genes that couple host cell division to plasmid proliferation.

  1983cited by this paper
• The F Plasmid

  1981cited by this paper
• Analysis of gene control signals by DNA fusion and cloning in Escherichia coli.

  1980influential reference
• Construction and characterization of new cloning vehicles. III. Derivatives of plasmid pBR322 carrying unique Eco RI sites for selection of Eco RI generated recombinant DNA molecules.

  1978cited by this paper
• Genetics of the relB locus in Escherichia coli

  1977influential reference
• Isolation of relaxed-control mutants of escherichia coli K-12 which are sensitive to glucose starvation.

  1976cited by this paper
• Experiments in molecular genetics

  1972cited by this paper
• On Stringent Response

  1972cited by this paper
• DNA replication and the division cycle in Escherichia coli

  1967influential reference
• [New mutants for regulation of RNA synthesis].

  1965cited by this paper
• Regulation of ribosomal and transfer RNA synthesis.

  1962cited by this paper
• A genetic locus for the regulation of ribonucleic acid synthesis.

  1961cited by this paper
• STUDIES ON LYSOGENESIS I

  1951influential reference

• The Hok bacterial toxin: diversity, toxicity, distribution and genomic localization

  2026cites this paper
• Poly-immunity arrays associated with Rhs toxins confer wide protection against competitors.

  2025cites this paper
• Importance of chick origin in introducing multidrug-resistant and extended-spectrum beta-lactamase-producing Enterobacteriaceae into an organic broiler farm.

  2025cites this paper
• Widespread deployment of the human CD38 ADP-ribosyl cyclase fold in antibacterial and anti-eukaryotic polymorphic toxins

  2025cites this paper
• Novel oligomerization state of DinJ-YafQ complex from Vibrio cholerae-Structural and biochemical insights.

  2025cites this paper
• Antitoxin control of optimal transcriptional repression in the atypical HigB–HigA toxin–antitoxin system from Proteus vulgaris

  2025cites this paper
• The Escherichia coli RelB antitoxin C terminus is essential for RelE toxin suppression and transcriptional repression

  2025cites this paper
• Secure biosystems design in Saccharomyces cerevisiae establishes effective biocontainment strategies and mechanisms of escape

  2025cites this paper
• Type II toxin-antitoxin systems as stress-responsive survival circuits in archaea and bacteria

  2025cites this paper
• Type II Toxin-Antitoxin Systems in Escherichia coli

  2025cites this paper
• Curli-independent defense against Bdellovibrio bacteriovorus in E. coli

  2025cites this paper
• Mono- and multidomain defense toxins of the RelE/ParE superfamily

  2025cites this paper
• Guided tour through the small protein landscape of Methanosarcina mazei using proteomics and biochemical approaches

  2025cites this paper
• Molecular Basis of Operator Recognition by the DNA-Binding Domain of Escherichia coli HigA Antitoxin.

  2025cites this paper
• Structural Variations and Rearrangements in Bacterial Type II Toxin-Antitoxin Systems.

  2024cites this paper
• The zoonotic pathogen Wohlfahrtiimonas chitiniclastica – current findings from a clinical and genomic perspective

  2024cites this paper
• A genetically encoded biosensor to monitor dynamic changes of c-di-GMP with high temporal resolution

  2024cites this paper
• Multi-omics analysis elucidates the host-microbiome interplay in severe udder cleft dermatitis lesions in dairy cows

  2024cites this paper
• Time to lysis determines phage sensitivity to a cytidine deaminase toxin/antitoxin bacterial defense system

  2023cites this paper
• Tuning the expression of the bacterial relBE toxin-antitoxin system in Saccharomyces cerevisiae allows characterizing the subsequent growth inhibition.

  2023cites this paper
• Improved cryptic plasmids in probiotic Escherichia coli Nissle 1917 for antibiotic-free pathway engineering

  2023influential citation
• The structural basis of hyperpromiscuity in a core combinatorial network of Type II toxin-antitoxin and related phage defence systems

  2023cites this paper
• An Orphan VrgG Auxiliary Module Related to the Type VI Secretion Systems from Pseudomonas ogarae F113 Mediates Bacterial Killing

  2023cites this paper
• Replication cycle timing determines phage sensitivity to a cytidine deaminase toxin/antitoxin bacterial defense system

  2023cites this paper
• A Wohlfahrtiimonas chitiniclastica with a novel type of blaVEB–1-carrying plasmid isolated from a zebra in China

  2023cites this paper
• Unraveling the evolutionary dynamics of toxin-antitoxin systems in diverse genetic lineages of Escherichia coli including the high-risk clonal complexes

  2023cites this paper
• Type II Toxin–Antitoxin Systems in Pseudomonas aeruginosa

  2023influential citation
• An in-depth investigation of the microbiota and its virulence factors associated 11 with severe udder cleft dermatitis lesions.

  2023influential citation
• Uncovering new families and folds in the natural protein universe

  2023cites this paper
• Diverse genetic contexts of HicA toxin domains propose a role in anti-phage defense

  2023cites this paper
• An Isotope-Labeled Single-Cell Raman Spectroscopy Approach for Tracking the Physiological Evolution Trajectory of Bacteria toward Antibiotic Resistance.

  2023cites this paper
• Structural basis for kinase inhibition in the tripartite E. coli HipBST toxin–antitoxin system

  2022cites this paper
• Toxin–antitoxin systems in pathogenic Vibrio species: a mini review from a structure perspective

  2022cites this paper
• Maintenance of the Shigella sonnei Virulence Plasmid Is Dependent on Its Repertoire and Amino Acid Sequence of Toxin-Antitoxin Systems

  2022cites this paper
• Identification, functional characterization, assembly and structure of ToxIN type III toxin–antitoxin complex from E. coli

  2022cites this paper
• Genome sequencing and comparative analysis of Wolbachia strain wAlbA reveals Wolbachia-associated plasmids are common

  2022cites this paper
• A Novel Biosensor Reveals Dynamic Changes of C-di-GMP in Differentiating Cells with Ultra-High Temporal Resolution

  2022cites this paper
• Intrabacterial Regulation of a Cytotoxic Effector by Its Cognate Metaeffector Promotes Legionella pneumophila Virulence

  2022cites this paper
• Diversity and function of arthropod endosymbiont toxins.

  2021cites this paper
• DnaJ and ClpX Are Required for HitRS and HssRS Two-Component System Signaling in Bacillus anthracis

  2021cites this paper
• Photorhabdus antibacterial Rhs polymorphic toxin inhibits translation through ADP-ribosylation of 23S ribosomal RNA

  2021cites this paper
• Gearing up to Unwind: Designing Structured Messenger RNA to Biochemically and Structurally Investigate the Ribosomal mRNA Helicase

  2021cites this paper
• 12/111phiA Prophage Domestication Is Associated with Autoaggregation and Increased Ability to Produce Biofilm in Streptococcus agalactiae

  2021influential citation
• Molecular mechanism regulating transcriptional control of the hig toxin-antitoxin locus of antibiotic-resistance plasmid Rts1 from Proteus vulgaris

  2021cites this paper
• Biological Functions of Type II Toxin-Antitoxin Systems in Bacteria

  2021cites this paper
• Minimalistic mycoplasmas harbor different functional toxin-antitoxin systems

  2021cites this paper
• Proteome Dynamics during Antibiotic Persistence and Resuscitation

  2021cites this paper
• Toxin-antitoxin systems and their medical applications: current status and future perspective

  2021cites this paper
• Degradation of the E. coli antitoxin MqsA by the proteolytic complex ClpXP is regulated by zinc occupancy and oxidation

  2021cites this paper
• PasT of Escherichia coli sustains antibiotic tolerance and aerobic respiration as a bacterial homolog of mitochondrial Coq10

  2020cites this paper
• The role of toxin:antitoxin systems and insertion sequences in the loss of virulence in Shigella sonnei

  2020cites this paper
• Bacterial bug-out bags: outer membrane vesicles and their proteins and functions

  2020cites this paper
• Distinct Morphological Fates of Uropathogenic Escherichia coli Intracellular Bacterial Communities: Dependency on Urine Composition and pH

  2020cites this paper
• The Toxin-Antitoxin Systems of the Opportunistic Pathogen Stenotrophomonas maltophilia of Environmental and Clinical Origin

  2020cites this paper
• Abasy Atlas v2.2: The most comprehensive and up-to-date inventory of meta-curated, historical, bacterial regulatory networks, their completeness and system-level characterization

  2020cites this paper
• Type II and type IV toxin–antitoxin systems show different evolutionary patterns in the global Klebsiella pneumoniae population

  2020cites this paper
• Type II Toxin-Antitoxin Systems: Evolution and Revolutions

  2020cites this paper
• Proteome dynamics in persisting and resuscitating bacterial cells

  2020cites this paper
• Plasmid Vectors for in Vivo Selection-Free Use with the Probiotic E. coli Nissle 1917

  2020cites this paper
• Persistence and β-glucan formation of beer-spoiling lactic acid bacteria in wheat and rye sourdoughs.

  2020cites this paper
• A Novel Plasmid pALWVS1.4 from Acinetobacter lwoffii Strain VS15, Carrying the Chloramphenicol Resistance Gene

  2020cites this paper
• A Novel Plasmid pALWVS1.4 from Acinetobacter lwoffii Strain VS15, Carrying the Chloramphenicol Resistance Gene

  2020cites this paper
• The positively charged active site of the bacterial toxin RelE causes a large shift in the general base pKa.

  2020cites this paper
• Specialised functions of two common plasmid mediated toxin-antitoxin systems, ccdAB and pemIK, in Enterobacteriaceae

  2020cites this paper
• 2.09 Å resolution structure of E. coli HigBA toxin-antitoxin complex reveals an ordered DNA-binding domain and intrinsic dynamics in antitoxin.

  2020cites this paper
• Towards Exploring Toxin-Antitoxin Systems in Geobacillus: A Screen for Type II Toxin-Antitoxin System Families in a Thermophilic Genus

  2019cites this paper
• The molecular basis of HicA dependent binding of HicB to DNA

  2019cites this paper
• Crystal Structure of VapBC-1 from Nontypeable Haemophilus influenzae and the Effect of PIN Domain Mutations on Survival during Infection

  2019cites this paper
• Linking toxin-antitoxin systems with phenotypes: A Staphylococcus aureus viewpoint.

  2019cites this paper
• YtfK activates the stringent response by triggering the alarmone synthetase SpoT in Escherichia coli

  2019cites this paper
• Intramolecular Interactions Dominate the Autoregulation of Escherichia coli Stringent Factor RelA

  2019cites this paper
• Characterization of HicAB toxin-antitoxin module of Sinorhizobium meliloti

  2019cites this paper
• The antitoxin MqsA homologue in Pseudomonas fluorescens 2P24 has a rewired regulatory circuit through evolution

  2019cites this paper
• Robust Stoichiometry of FliW-CsrA Governs Flagellin Homeostasis and Cytoplasmic Organization in Bacillus subtilis

  2019cites this paper
• Persister Formation Driven by TisB-Dependent Membrane Depolarization

  2019cites this paper
• ParT: Prs ADP-ribosylating toxin bound to cognate antitoxin ParS

  2019cites this paper
• Serine-Threonine Kinases Encoded by Split hipA Homologs Inhibit Tryptophanyl-tRNA Synthetase

  2019cites this paper
• Structural and Biochemical Characterization of the Cognate and Heterologous Interactions of the MazEF-mt9 TA System.

  2019cites this paper
• TAome analysis of type-II toxin-antitoxin system from Xenorhabdus nematophila

  2018cites this paper
• Identification of Three Type II Toxin-Antitoxin Systems in Streptococcus suis Serotype 2

  2018cites this paper
• sRNA-dependent control of curli biosynthesis in Escherichia coli: McaS directs endonucleolytic cleavage of csgD mRNA

  2018cites this paper
• Identification and functional characterization of type II toxin/antitoxin systems in Aggregatibacter actinomycetemcomitans

  2018cites this paper
• Toxins, Targets, and Triggers: An Overview of Toxin-Antitoxin Biology.

  2018cites this paper
• ParST is a widespread toxin–antitoxin module that targets nucleotide metabolism

  2018cites this paper
• Toxin-antitoxin systems and regulatory mechanisms in Mycobacterium tuberculosis.

  2018cites this paper
• Diversité et plasticité des petits plasmides d'Aeromonas salmonicida ssp. salmonicida

  2018influential citation
• Structural and biochemical characterization on the cognate and heterologous interactions of the MazEF-mt9 TA system

  2018cites this paper
• A plasmid from an Antarctic haloarchaeon uses specialized membrane vesicles to disseminate and infect plasmid-free cells

  2017cites this paper
• Comparative genomics reveals the presence of putative toxin–antitoxin system in Wolbachia genomes

  2017cites this paper
• The Pseudomonas putida T6SS is a plant warden against phytopathogens

  2017cites this paper
• Importance of the E. coli DinJ antitoxin carboxy terminus for toxin suppression and regulated proteolysis

  2017cites this paper
• The Ssl2245-Sll1130 Toxin-Antitoxin System Mediates Heat-induced Programmed Cell Death in Synechocystis sp. PCC6803*

  2017cites this paper
• Wing phosphorylation is a major functional determinant of the Lrs14‐type biofilm and motility regulator AbfR1 in Sulfolobus acidocaldarius

  2017cites this paper
• Structural basis for maintenance of bacterial outer membrane lipid asymmetry

  2017cites this paper
• Molecular characterization of the pA3J1 plasmid from the psychrotolerant Antarctic bacterium Pseudomonas sp. ANT_J3.

  2017cites this paper
• Commentary: What Is the Link between Stringent Response, Endoribonuclease Encoding Type II Toxin-Antitoxin Systems and Persistence?

  2017cites this paper
• Higher-Order Structure in Bacterial VapBC Toxin-Antitoxin Complexes.

  2017cites this paper
• Re-wiring of energy metabolism promotes viability during hyperreplication stress in E. coli

  2017cites this paper
• A RelE/ParE superfamily toxin in Vibrio parahaemolyticus has DNA nicking endonuclease activity.

  2017cites this paper
• Construction and validation of versatile broad-host range plasmid pBZ 485

  2017cites this paper