Extrinsic regulation of hematopoietic stem cells in development, homeostasis and diseases

No abstract is available for this paper.

• Publication year

  2017

• Venue

  Wiley Interdisciplinary Reviews: Developmental Biology

• Publication date

  2017-05-31

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/wdev.279PMID 28561893PMCID PMC5642943
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Numerous niches for hematopoietic stem cells remain empty during homeostasis.

  2017cited by this paper
• Fetal liver hematopoietic stem cell niches associate with portal vessels

  2016cited by this paper
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  2016cited by this paper
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  2016cited by this paper
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  2016cited by this paper
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• Hematopoietic Stem Cells Are the Major Source of Multilineage Hematopoiesis in Adult Animals.

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• Targeting the leukemia–stroma interaction in acute myeloid leukemia: rationale and latest evidence

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• Age-dependent modulation of vascular niches for haematopoietic stem cells

  2016influential reference
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  2016cited by this paper
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  2015cited by this paper
• ROBO4-Mediated Vascular Integrity Regulates the Directionality of Hematopoietic Stem Cell Trafficking

  2015cited by this paper
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  2015influential reference
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  2015cited by this paper
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  2015cited by this paper
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  2015cited by this paper
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  2015influential reference
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• Inflammatory signaling regulates embryonic hematopoietic stem and progenitor cell production

  2014cited by this paper
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  2014cited by this paper
• Cytotoxic CD8+ T cells stimulate hematopoietic progenitors by promoting cytokine release from bone marrow mesenchymal stromal cells.

  2014cited by this paper
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  2014cited by this paper
• Foxc1 is a critical regulator of haematopoietic stem/progenitor cell niche formation

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• Leukemogenesis Induced by an Activating β-catenin mutation in Osteoblasts

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• Neuropathy of haematopoietic stem cell niche is essential for myeloproliferative neoplasms

  2014influential reference
• Regulation of hematopoietic and leukemic stem cells by the immune system

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• Direct measurement of local oxygen concentration in the bone marrow of live animals

  2014cited by this paper
• Notch-dependent repression of miR-155 in the bone marrow niche regulates hematopoiesis in an NF-κB-dependent manner.

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• A Subset of Chondrogenic Cells Provides Early Mesenchymal Progenitors in Growing Bones

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• Myelodysplastic cells in patients reprogram mesenchymal stromal cells to establish a transplantable stem cell niche disease unit.

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• Infection mobilizes hematopoietic stem cells through cooperative NOD-like receptor and Toll-like receptor signaling.

  2014cited by this paper
• The neural crest is a source of mesenchymal stem cells with specialized hematopoietic stem cell niche function

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• Leptin-receptor-expressing mesenchymal stromal cells represent the main source of bone formed by adult bone marrow.

  2014cited by this paper
• Interferon gamma signaling positively regulates hematopoietic stem cell emergence.

  2014cited by this paper
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  2014cited by this paper
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  2014cited by this paper
• Proinflammatory signaling regulates hematopoietic stem cell emergence.

  2014cited by this paper
• Acute myelogenous leukemia-induced sympathetic neuropathy promotes malignancy in an altered hematopoietic stem cell niche.

  2014cited by this paper
• Endothelial Jagged-1 is necessary for homeostatic and regenerative hematopoiesis.

  2013cited by this paper
• PDGFRα and CD51 mark human Nestin+ sphere-forming mesenchymal stem cells capable of hematopoietic progenitor cell expansion

  2013cited by this paper
• Quantitative imaging of haematopoietic stem and progenitor cell localization and hypoxic status in the bone marrow microenvironment

  2013cited by this paper
• Megakaryocytes regulate hematopoietic stem cell quiescence via Cxcl4 secretion

  2013cited by this paper
• TGFβ restores hematopoietic homeostasis after myelosuppressive chemotherapy

  2013cited by this paper
• Megakaryocytes promote murine osteoblastic HSC niche expansion and stem cell engraftment after radioablative conditioning.

  2013cited by this paper
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  2013cited by this paper
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  2013cited by this paper
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• Epidermal Growth Factor Regulates Hematopoietic Regeneration Following Radiation Injury

  2013cited by this paper
• Arteriolar niches maintain haematopoietic stem cell quiescence

  2013cited by this paper
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  2013cited by this paper
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  2013cited by this paper
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  2013cited by this paper
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  2013cited by this paper
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  2013cited by this paper
• Myeloproliferative neoplasia remodels the endosteal bone marrow niche into a self-reinforcing leukemic niche.

  2013cited by this paper
• Osteoblastic N-cadherin is not required for microenvironmental support and regulation of hematopoietic stem and progenitor cells.

  2012cited by this paper
• Trophoblasts regulate the placental hematopoietic niche through PDGF-B signaling.

  2012cited by this paper
• Hematopoietic stem cell heterogeneity takes center stage.

  2012cited by this paper
• Rantes/Ccl5 influences hematopoietic stem cell subtypes and causes myeloid skewing.

  2012cited by this paper
• Altered microenvironmental regulation of leukemic and normal stem cells in chronic myelogenous leukemia.

  2012cited by this paper
• Noncanonical Wnt signaling maintains hematopoietic stem cells in the niche.

  2012cited by this paper
• Identification of a clonally expanding haematopoietic compartment in bone marrow

  2012cited by this paper
• CXCL12 Production by Early Mesenchymal Progenitors is Required for Hematopoietic Stem Cell Maintenance

  2012cited by this paper
• Osteoblastic expansion induced by parathyroid hormone receptor signaling in murine osteocytes is not sufficient to increase hematopoietic stem cells.

  2012cited by this paper
• Origin of blood cells and HSC production in the embryo.

  2012cited by this paper
• Differential regulation of myeloid leukemias by the bone marrow microenvironment

  2012cited by this paper
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  2012cited by this paper
• Chimerism levels after stem cell transplantation are primarily determined by the ratio of donor to host stem cells.

  2011cited by this paper
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  2011cited by this paper
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  2011cited by this paper
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  2011cited by this paper
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  2011cited by this paper
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  2011cited by this paper
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  2011influential reference
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  2011cited by this paper
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  2011cited by this paper
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  2011cited by this paper
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  2011cited by this paper
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  2010cited by this paper
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  2010cited by this paper
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  2010cited by this paper
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  2010cited by this paper
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  2010influential reference
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  2010cited by this paper
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  2010cited by this paper
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  2010cited by this paper
• Regulation of the HIF-1alpha level is essential for hematopoietic stem cells.

  2010cited by this paper
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  2010cited by this paper
• Endothelial cells are essential for the self-renewal and repopulation of Notch-dependent hematopoietic stem cells.

  2010cited by this paper
• Mesenchymal and haematopoietic stem cells form a unique bone marrow niche

  2010cited by this paper

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• Decoding Clonal Hematopoiesis: Emerging Themes and Novel Mechanistic Insights

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• Cellular plasticity of the bone marrow niche promotes hematopoietic stem cell regeneration

  2023cites this paper
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  2022cites this paper
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  2021cites this paper
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• The Role of N6-methyladenosine RNA Methylation in the Regulation of Hematopoietic Stem Cells

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