Cancer is one of the leading causes of death worldwide. Many treatments have been developed so far, although effective, suffer from severe side effects due to low selectivity. Nanoparticles can improve the therapeutic index of their delivered drugs by specifically transporting them to tumors. However, their exogenous nature usually leads to fast clearance by mononuclear phagocytic system. Recently, cell membrane-camouflaged nanoparticles have been investigated for cancer therapy, taking advantages of excellent biocompatibility and versatile functionality of cell membranes. In this review, we summarized source materials and procedures that have been used for constructing and characterizing biomimetic nanoparticles with a focus on their application in cancer therapy.
Preparation and Application of Cell Membrane-Camouflaged Nanoparticles for Cancer Therapy
Yihui Zhai,Jinghan Su,W. Ran,Pengcheng Zhang,Qi Yin,Zhiwen Zhang,Haijun Yu,Yaping Li
Published 2017 in Theranostics
ABSTRACT
PUBLICATION RECORD
- Publication year
2017
- Venue
Theranostics
- Publication date
2017-06-25
- Fields of study
Medicine, Materials Science, Chemistry
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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