Cytoplasmic phospholipase A2 expression in human colon adenocarcinoma is correlated with cyclooxygenase-2 expression and contributes to prostaglandin E2 production.

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Cancer Letters

• Publication date

  2006-11-18

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/J.CANLET.2005.11.045PMID 16458424
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2002influential reference
• Cyclooxygenase 2- and prostaglandin E(2) receptor EP(2)-dependent angiogenesis in Apc(Delta716) mouse intestinal polyps.

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• Potential role of group X secretory phospholipase A2 in cyclooxygenase‐2‐dependent PGE2 formation during colon tumorigenesis

  2000influential reference
• The expanding superfamily of phospholipase A(2) enzymes: classification and characterization.

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  1998cited by this paper
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  1998cited by this paper
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  1998cited by this paper
• Reduced COX-2 protein in colorectal cancer with defective mismatch repair.

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• Gene expression of cyclooxygenase-2, group II and cytosolic phospholipase A2 in human colorectal cancer.

  1998cited by this paper
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  1998cited by this paper
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  1997cited by this paper
• de la Chapelle, A.

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• High molecular weight phospholipase A2: its occurrence and quantification in human colon cancer and normal mucosa.

  1997influential reference
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• Tumor necrosis factor-α induces the 85-kDa cytosolic phospholipase A2 gene expression in human bronchial epithelial cells

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• High molecular weight phospholipase A2 and fatty acids in human colon tumours and associated normal tissue.

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• Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas.

  1994cited by this paper
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  1994cited by this paper
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