Presence of functional TLR2 and TLR4 on human adipocytes

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Histochemistry and Cell Biology

• Publication date

  2007-01-18

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1007/s00418-006-0230-1PMID 16988837
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Influence of CD14 on Ligand Interactions between Lipopolysaccharide and Its Receptor Complex1

  2005cited by this paper
• Surface protein expression between human adipose tissue-derived stromal cells and mature adipocytes

  2005influential reference
• TGF-α Regulates TLR Expression and Function on Epidermal Keratinocytes1

  2005cited by this paper
• TGF-alpha regulates TLR expression and function on epidermal keratinocytes.

  2005cited by this paper
• Modulatory effects of sCD14 and LBP on LPS-host cell interactions:

  2005cited by this paper
• Expression of TLR2 and TLR4 Messenger RNA in the Epithelial Cells of the Nasal Airway

  2005cited by this paper
• Modulatory effects of sCD14 and LBP on LPS-host cell interactions

  2005influential reference
• The proatherogenic cytokine interleukin-18 is secreted by human adipocytes.

  2005cited by this paper
• Structure–activity relationship of alginate oligosaccharides in the induction of cytokine production from RAW264.7 cells

  2005cited by this paper
• Innate immunity: an overview.

  2004cited by this paper
• The adipocyte as an endocrine cell.

  2004cited by this paper
• Innate immune functions of the keratinocytes. A review.

  2004cited by this paper
• Toll-Like Receptor (TLR)2 and TLR4 Agonists Regulate CCR Expression in Human Monocytic Cells1

  2004cited by this paper
• Toll-like receptors in innate immunity.

  2004cited by this paper
• Human adipose cells as candidates in defense and tissue remodeling phenomena.

  2003cited by this paper
• Toll‐Like receptor 4 mediates inflammatory signaling by bacterial lipopolysaccharide in human hepatic stellate cells

  2003cited by this paper
• Lipoteichoic Acid (LTA) of Streptococcus pneumoniaeand Staphylococcus aureus Activates Immune Cells via Toll-like Receptor (TLR)-2, Lipopolysaccharide-binding Protein (LBP), and CD14, whereas TLR-4 and MD-2 Are Not Involved*

  2003influential reference
• [Adipose tissue: a storage and secretory organ].

  2002cited by this paper
• Induction of cytokine production in human T cells and monocytes by highly purified lipoteichoic acid: involvement of Toll-like receptors and CD14.

  2002cited by this paper
• Adipose tissues display differential phagocytic and microbicidal activities depending on their localization

  2001cited by this paper
• Toll-like receptors (TLRs) signalling and expression pattern

  2001cited by this paper
• Identification of Toll-like receptor 4 (Tlr4) as the sole conduit for LPS signal transduction: genetic and evolutionary studies

  2001cited by this paper
• Differential roles of Toll-like receptors in the elicitation of proinflammatory responses by macrophages

  2001cited by this paper
• Regulation of innate immune responses by Toll-like receptors.

  2001cited by this paper
• Regulation of Toll-Like Receptors in Human Monocytes and Dendritic Cells1

  2001cited by this paper
• Identification of Toll-like receptor 4 (Tlr4) as the sole conduit for LPS signal transduction: genetic and evolutionary studies.

  2001cited by this paper
• The Lipopolysaccharide-activated Toll-like Receptor (TLR)-4 Induces Synthesis of the Closely Related Receptor TLR-2 in Adipocytes*

  2000influential reference
• Adipose tissue : a storage and secretory organ

  1999cited by this paper
• Regulation of tumour necrosis factor-alpha release from human adipose tissue in vitro.

  1999cited by this paper
• Vancomycin down-regulates lipopolysaccharide-induced tumour necrosis factor alpha (TNF alpha) production and TNF alpha-mRNA accumulation in human blood monocytes.

  1997influential reference
• Vancomycin down-regulates lipopolysaccharide-induced tumour necrosis factor alpha (TNFα) production and TNFa-mRNA accumulation in human blood monocytes

  1997influential reference
• A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

  1997cited by this paper
• The CD38 lymphocyte differentiation marker: new insight into its ectoenzymatic activity and its role as a signal transducer.

  1997cited by this paper
• The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults.

  1996cited by this paper
• Soluble CD14 and lipopolysaccharide‐binding protein from bovine serum enable bacterial lipopolysaccharide‐mediated cytotoxicity and activation of bovine vascular endothelial cells in vitro

  1996cited by this paper
• Purification of lipopolysaccharide-binding protein from bovine serum.

  1996cited by this paper
• Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance.

  1995cited by this paper
• Isolation and structure of a cDNA encoding the B1 (CD20) cell-surface antigen of human B lymphocytes.

  1988cited by this paper

• The Role of TLRs in Obesity and Its Related Metabolic Disorders

  2025cites this paper
• Development and characterization of a chicory extract fermented by Akkermansia muciniphila: An in vitro study on its potential to modulate obesity-related inflammation

  2025cites this paper
• Serum levels of Wnt5a in Egyptian women with obesity and their association with toll like receptor 2 Arg753Gln gene polymorphism in a pilot case control study of obesity as a state of metaflammation

  2025cites this paper
• Message Transmission Between Adipocyte and Macrophage in Obesity.

  2024cites this paper
• Links Between Adipose Tissue Gene Expression of Gut Leakage Markers, Circulating Levels, Anthropometrics, and Diet in Patients with Coronary Artery Disease

  2024cites this paper
• Soy Lecithin in High-Fat Diets Exerts Dual Effects on Adipose Tissue vs Ileum.

  2023cites this paper
• On the Immunometabolic Role of NF-κB in Adipocytes

  2022cites this paper
• NUCB2/Nesfatin-1 Reduces Obesogenic Diet Induced Inflammation in Mice Subcutaneous White Adipose Tissue

  2022cites this paper
• Links between Insulin Resistance and Periodontal Bacteria: Insights on Molecular Players and Therapeutic Potential of Polyphenols

  2022cites this paper
• Antimicrobial production by perifollicular dermal preadipocytes is essential to the pathophysiology of acne

  2022cites this paper
• Palmitic acid up regulates Gal-3 and induces insulin resistance in macrophages by mediating the balance between KLF4 and NF-κB

  2021cites this paper
• Regulation of CAMP (cathelicidin antimicrobial peptide) expression in adipocytes by TLR 2 and 4

  2021cites this paper
• Assessment of NF-κB Inhibitor (SN50) Effect on Adipose Tumor Necrosis Factor-Alpha and Angiotensinogen Secretion and Expression

  2021cites this paper
• Impact of thermogenesis induced by chronic β3-adrenergic receptor agonist treatment on inflammatory and infectious response during bacteremia in mice

  2021cites this paper
• Assessment of NF-κB-SN50’s Effect on Adipose Tumor Necrosis Factor-Alpha and Angiotensinogen Secretion and Expression

  2020cites this paper
• Gene expression level of toll-like receptor 4 and insulin receptor substrate 1 in type II diabetic Malay patients and their first-degree relatives.

  2020cites this paper
• Susceptibility rhythm to bacterial endotoxin in myeloid clock-knockout mice

  2019cites this paper
• Human Toll-Like Receptor 4 (hTLR4): Structural and functional dynamics in cancer.

  2019cites this paper
• The Omega-3 Fatty Acids EPA and DHA, as a Part of a Murine High-Fat Diet, Reduced Lipid Accumulation in Brown and White Adipose Tissues

  2019cites this paper
• Substrate structure-activity relationship reveals a limited lipopolysaccharide chemotype range for intestinal alkaline phosphatase

  2019cites this paper
• BIOCHEMICAL STUDIES OF HIPPOCAMPAL GENE EXPRESSION OF BRAIN-DERIVED NEUROTROPIC FACTOR AND TOLL-LIKE RECEPTOR-4 IN DIABETIC RATS EXPOSED TO CHRONIC STRESS: EFFECTS OF ANTIDEPRESSANT DRUGS

  2018cites this paper
• The Impact of Different Obesogenic Diets on the Severity of the Obese Phenotype and Colon Health in Male C57Bl/6 Mice

  2018cites this paper
• Linkage of Infection to Adverse Systemic Complications: Periodontal Disease, Toll-Like Receptors, and Other Pattern Recognition Systems

  2018cites this paper
• Establishment of defined culture conditions for the differentiation, long-term maintenance and co-culture of adipose-derived stem cells for the setup of human vascularized adipose tissue

  2018cites this paper
• Single Nucleotide Polymorphisms in CD 14 and Toll-like Receptor 4 Genes in Patients with Polycystic Ovarian Syndrome

  2018cites this paper
• Adipocyte-Macrophage Cross-Talk in Obesity.

  2017cites this paper
• Secretory leukocyte protease inhibitor promising protective roles in obesity-associated atherosclerosis

  2017cites this paper
• Etiology and Pathophysiology A vicious circle in chronic lymphoedema pathophysiology ?

  2017cites this paper
• Porphyromonas gingivalis lipopolysaccharides act exclusively through TLR4 with a resilience between mouse and human

  2017cites this paper
• Porphyromonas gingivalis lipopolysaccharide induces pro-inflammatory adipokine secretion and oxidative stress by regulating Toll-like receptor-mediated signaling pathways and redox enzymes in adipocytes.

  2017cites this paper
• Anti‐inflammatory and antioxidant effects of polyphenols extracted from Antirhea borbonica medicinal plant on adipocytes exposed to Porphyromonas gingivalis and Escherichia coli lipopolysaccharides

  2017cites this paper
• Postprandial low-grade inflammation does not specifically require TLR4 activation in the rat

  2017cites this paper
• Particulate matter exposure is associated with inflammatory gene methylation in obese subjects

  2017cites this paper
• Innate Immunity of Adipose Tissue in Rodent Models of Local and Systemic Staphylococcus aureus Infection

  2017cites this paper
• EGF and hydrocortisone as critical factors for the co-culture of adipogenic differentiated ASCs and endothelial cells.

  2017cites this paper
• A vicious circle in chronic lymphoedema pathophysiology? An adipocentric view

  2017cites this paper
• Dietary fatty acids modulate adipocyte TNFa production via regulation of its DNA promoter methylation levels.

  2017cites this paper
• Integrated Immunomodulatory Mechanisms through which Long-Chain n-3 Polyunsaturated Fatty Acids Attenuate Obese Adipose Tissue Dysfunction

  2017influential citation
• TLR4-dependant pro-inflammatory effects of HMGB1 on human adipocyte

  2016cites this paper
• Association of TLR2 S450S and ICAM1 K469E polymorphisms with polycystic ovary syndrome (PCOS) and obesity.

  2016cites this paper
• Pathophysiology of Metabolic Syndrome: Part II—Influence of Inflammatory Status and Oxidative Stress

  2015cites this paper
• Advanced Application of Porcine Intramuscular Adipocytes for Evaluating Anti-Adipogenic and Anti-Inflammatory Activities of Immunobiotics

  2015cites this paper
• Experimental Hyperglycemia Induces an Increase of Monocyte and T-Lymphocyte Content in Adipose Tissue of Healthy Obese Women

  2015cites this paper
• Antioxidant polyphenol-rich extracts from the medicinal plants Antirhea borbonica, Doratoxylon apetalum and Gouania mauritiana protect 3T3-L1 preadipocytes against H2O2, TNFα and LPS inflammatory mediators by regulating the expression of superoxide dismutase and NF-κB genes

  2015cites this paper
• Construction of Escherichia coli Mutant with Decreased Endotoxic Activity by Modifying Lipid A Structure

  2015cites this paper
• Substitution in Amino Acid 70 of Hepatitis C Virus Core Protein Changes the Adipokine Profile via Toll-Like Receptor 2/4 Signaling

  2015cites this paper
• TLR4 signalling in osteoarthritis—finding targets for candidate DMOADs

  2015cites this paper
• The modulation of inflammatory adipokines by n-3 and n-6 polyunsaturated fatty acids using in vitro models that mimic obese adipose tissue

  2015cites this paper
• Long-chain n-3 Polyunsaturated Fatty Acids Mitigate Inflammatory Adipokines Derived from Adipocyte-Macrophage Cross-talk and Ensuing Changes in M1-Macrophage Polarization Markers

  2015cites this paper
• Obesity-Driven Gut Microbiota Inflammatory Pathways to Metabolic Syndrome

  2015cites this paper
• Obesity-related factors involved in endoplasmic reticulum stress induction in adipocytes

  2015cites this paper
• A novel metabolic regulator

  2014cites this paper
• A Comparative Review of Toll-Like Receptor 4 Expression and Functionality in Different Animal Species

  2014cites this paper
• Obesity, Insulin Resistance, and Inflammaging

  2014cites this paper
• Comparison of postprandial endotoxemia in male adolescents and male subjects above 50 years after a fat overload

  2014cites this paper
• Inflammation, advancing age and nutrition

  2014cites this paper
• Pattern Recognition Receptors and Aging

  2014cites this paper
• Crosstalk between adipocytes and immune cells in adipose tissue in an obese inflammatory state: role of contact-mediated signaling

  2013cites this paper
• Toll-like Rezeptor 4 als gemeinsamer Regulator von Energiestoffwechsel und Inflammation bei der Pathogenese des Insulinmangeldiabetes im Tiermodell der non-obese diabetic Maus

  2013cites this paper
• The immune cell transcription factor T-bet

  2013cites this paper
• Adiponectin: merely a bystander or the missing link to cardiovascular disease?

  2013cites this paper
• Influence of Obesity on Neurodegenerative Diseases

  2013cites this paper
• Phytochemicals and their impact on adipose tissue inflammation and diabetes.

  2013cites this paper
• Staphylococcal Superantigens Stimulate Immortalized Human Adipocytes to Produce Chemokines

  2013cites this paper
• Soluble HMGB1 Is a Novel Adipokine Stimulating IL-6 Secretion through RAGE Receptor in SW872 Preadipocyte Cell Line: Contribution to Chronic Inflammation in Fat Tissue

  2013cites this paper
• Inflammation triggers high mobility group box 1 (HMGB1) secretion in adipose tissue, a potential link to obesity.

  2013cites this paper
• Novel mechanisms regulating inflammatory gene expression in adipocytes

  2012influential citation
• Comparison of blood monocytes and adipose tissue macrophages in a mouse model diet-induced weight gain.

  2012cites this paper
• Toll-like receptors and diabetes: a therapeutic perspective.

  2012cites this paper
• TLR Signalling and Adapter Utilization in Primary Human In vitro Differentiated Adipocytes

  2012cites this paper
• Both inflammatory and classical lipolytic pathways are involved in lipopolysaccharide-induced lipolysis in human adipocytes

  2012cites this paper
• Effects of bitter melon and toll‐like receptor (TLR) 4 on glucose and lipid parameters in mice fed high fat diet

  2012cites this paper
• Fatty acids do not pay the toll: effect of SFA and PUFA on human adipose tissue and mature adipocytes inflammation

  2012cites this paper
• NOD1 activation induces innate immune responses and insulin resistance in human adipocytes.

  2012cites this paper
• Role of innate immune receptors TLR2 and TLR4 as mediators of the inflammatory reaction in human visceral adipose tissue.

  2012influential citation
• Postnatal Overfeeding Leads to Obesity and Exacerbated Febrile Responses to Lipopolysaccharide Throughout Life

  2012cites this paper
• Nucleotide-binding oligomerization domain-1 ligand induces inflammation and attenuates glucose uptake in human adipocytes.

  2012cites this paper
• Altered Subcutaneous Adipose Tissue Response to Systemic LPS Administration in Patients with Type 2 Diabetes

  2012cites this paper
• Immunity as a link between obesity and insulin resistance.

  2012cites this paper
• (n-3) Fatty acids alleviate adipose tissue inflammation and insulin resistance: mechanistic insights.

  2011cites this paper
• Involvement of toll-like receptor 4 in alveolar bone loss and glucose homeostasis in experimental periodontitis.

  2011cites this paper
• High glucose may decrease the innate immune through TLRs in cornea epithelium

  2011cites this paper
• New insights into adipose tissue dysfunction in insulin resistance

  2011cites this paper
• Stearidonic and eicosapentaenoic acids inhibit interleukin-6 expression in ob/ob mouse adipose stem cells via Toll-like receptor-2-mediated pathways.

  2011cites this paper
• Pathogenic obesity and nutraceuticals

  2011cites this paper
• Pregravid Obesity Associates With Increased Maternal Endotoxemia and Metabolic Inflammation

  2011cites this paper
• Toll-like receptors, inflammation, metabolism and obesity

  2011cites this paper
• The role of Ad-36 and its E4orf-1 protein in modulating glycemic control

  2011cites this paper
• Genetic and nutritional studies to elucidate the role of adipose tissue in the pathogenesis of metabolic syndrome

  2011cites this paper
• Inflammation of the adipose tissue (Part 4). Obesity: a new infectious disease? (a literature review)

  2011cites this paper
• PNS1100166 426..438

  2011cites this paper
• Palmitoylethanolamide, adipocytes and obesity-related inflammatory states

  2010cites this paper
• Toll-like Rezeptor 4 als Regulator der Diabetespathogenese im Tiermodell des humanen Typ 1 Diabetes

  2010cites this paper
• Regulation of angiotensinogen in adipocytes by polyunsaturated fatty acids

  2010cites this paper
• Adipokine dysregulation, adipose tissue inflammation and metabolic syndrome.

  2010cites this paper
• TLR4 and Insulin Resistance

  2010cites this paper
• Insulin Resistance and Increased Lipolysis in Bone Marrow Derived Adipocytes Stimulated with Agonists of Toll-like Receptors

  2010cites this paper
• Release of Inflammatory Mediators by Human Adipose Tissue Is Enhanced in Obesity and Primarily by the Nonfat Cells: A Review

  2010cites this paper
• Apolipoprotein CIII Induces Monocyte Chemoattractant Protein-1 and Interleukin 6 Expression Via Toll-Like Receptor 2 Pathway in Mouse Adipocytes: Retracted

  2010cites this paper
• Signaling pathways involved in LPS induced TNFalpha production in human adipocytes

  2010cites this paper