See Hansson and Mormino (doi:10.1093/brain/awy065) for a scientific commentary on this article. Where should measurements be taken to best capture tau accumulation in ageing and Alzheimer’s disease? Jack et al. report that in clinically symptomatic stages of Alzheimer’s disease, tau accumulation occurs throughout the brain, rather than only in specific areas. Rate measurements from simple meta-regions of interest may be sufficient to capture progressive within-person tau accumulation.
Longitudinal tau PET in ageing and Alzheimer’s disease
C. Jack,H. Wiste,C. Schwarz,V. Lowe,M. Senjem,P. Vemuri,S. Weigand,T. Therneau,D. Knopman,J. Gunter,David T. Jones,J. Graff‐Radford,K. Kantarci,R. Roberts,M. Mielke,M. Machulda,R. Petersen
Published 2018 in Brain : a journal of neurology
ABSTRACT
PUBLICATION RECORD
- Publication year
2018
- Venue
Brain : a journal of neurology
- Publication date
2018-03-12
- Fields of study
Medicine
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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