The meiosis-specific Cdc20 family-member Ama1 promotes binding of the Ssp2 activator to the Smk1 MAP kinase

Gregory Omerza,Chong Wai Tio,T. Philips,A. Diamond,A. Neiman,E. Winter

Published 2018 in Molecular Biology of the Cell

ABSTRACT

Smk1 is a meiosis-specific MAP kinase that is activated by a binding partner, Ssp2. This study shows that the meiosis-specific Cdc20 homologue, Ama1, triggers Ssp2/Smk1 complex formation at specialized meiotic membranes as nuclear segregation is being completed, thus triggering kinase activity at a specific place and time during this developmental program.

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